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Aliases for FAM185A Gene

Aliases for FAM185A Gene

  • Family With Sequence Similarity 185 Member A 2 3 5
  • Family With Sequence Similarity 185, Member A 2

External Ids for FAM185A Gene

Previous GeneCards Identifiers for FAM185A Gene

  • GC07P102177
  • GC07P102389
  • GC07P096751

Summaries for FAM185A Gene

GeneCards Summary for FAM185A Gene

FAM185A (Family With Sequence Similarity 185 Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM185A Gene

Genomics for FAM185A Gene

Regulatory Elements for FAM185A Gene

Promoters for FAM185A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM185A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM185A Gene

Chromosome:
7
Start:
102,748,944 bp from pter
End:
102,912,918 bp from pter
Size:
163,975 bases
Orientation:
Plus strand

Genomic View for FAM185A Gene

Genes around FAM185A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM185A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM185A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM185A Gene

Proteins for FAM185A Gene

  • Protein details for FAM185A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N0U4-F185A_HUMAN
    Recommended name:
    Protein FAM185A
    Protein Accession:
    Q8N0U4
    Secondary Accessions:
    • A8MUR7
    • B4DQD3
    • C9IZ91

    Protein attributes for FAM185A Gene

    Size:
    392 amino acids
    Molecular mass:
    42301 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM185A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM185A Gene

Proteomics data for FAM185A Gene at MOPED

Post-translational modifications for FAM185A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM185A Gene

No data available for DME Specific Peptides for FAM185A Gene

Domains & Families for FAM185A Gene

Protein Domains for FAM185A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM185A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM185A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FAM185A Gene

Function for FAM185A Gene

Phenotypes for FAM185A Gene

GenomeRNAi human phenotypes for FAM185A:
genes like me logo Genes that share phenotypes with FAM185A: view

Animal Model Products

CRISPR Products

miRNA for FAM185A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM185A Gene

Localization for FAM185A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM185A Gene COMPARTMENTS Subcellular localization image for FAM185A gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM185A Gene

Pathways & Interactions for FAM185A Gene

SuperPathways for FAM185A Gene

No Data Available

Interacting Proteins for FAM185A Gene

Gene Ontology (GO) - Biological Process for FAM185A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM185A Gene

Drugs & Compounds for FAM185A Gene

No Compound Related Data Available

Transcripts for FAM185A Gene

Unigene Clusters for FAM185A Gene

Family with sequence similarity 185, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM185A Gene

No ASD Table

Relevant External Links for FAM185A Gene

GeneLoc Exon Structure for
FAM185A
ECgene alternative splicing isoforms for
FAM185A

Expression for FAM185A Gene

mRNA expression in normal human tissues for FAM185A Gene

Protein differential expression in normal tissues from HIPED for FAM185A Gene

This gene is overexpressed in Heart (29.5), Peripheral blood mononuclear cells (24.2), and Liver (10.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for FAM185A Gene



SOURCE GeneReport for Unigene cluster for FAM185A Gene Hs.202543

genes like me logo Genes that share expression patterns with FAM185A: view

Protein tissue co-expression partners for FAM185A Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM185A Gene

Orthologs for FAM185A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM185A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM185A 35
  • 99.4 (n)
  • 98.98 (a)
FAM185A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM185A 36
  • 78 (a)
OneToOne
FAM185A 35
  • 87.21 (n)
  • 79.9 (a)
dog
(Canis familiaris)
Mammalia FAM185A 35
  • 86.15 (n)
  • 77.23 (a)
FAM185A 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam185a 16
Fam185a 35
  • 79.78 (n)
  • 74.39 (a)
Fam185a 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM185A 36
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM185A 36
  • 49 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam185a 35
  • 75.5 (n)
  • 69 (a)
chicken
(Gallus gallus)
Aves FAM185A 36
  • 60 (a)
OneToOne
FAM185A 35
  • 68.45 (n)
  • 59.55 (a)
lizard
(Anolis carolinensis)
Reptilia FAM185A 36
  • 46 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.4927 35
tropical clawed frog
(Silurana tropicalis)
Amphibia fam185a 35
  • 62.13 (n)
  • 50.3 (a)
zebrafish
(Danio rerio)
Actinopterygii FAM185A 36
  • 36 (a)
OneToOne
LOC100332968 35
  • 50.66 (n)
  • 39.76 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8187 36
  • 19 (a)
OneToOne
Species with no ortholog for FAM185A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM185A Gene

ENSEMBL:
Gene Tree for FAM185A (if available)
TreeFam:
Gene Tree for FAM185A (if available)

Paralogs for FAM185A Gene

Pseudogenes.org Pseudogenes for FAM185A Gene

genes like me logo Genes that share paralogs with FAM185A: view

No data available for Paralogs for FAM185A Gene

Variants for FAM185A Gene

Sequence variations from dbSNP and Humsavar for FAM185A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
VAR_039356 -

Structural Variations from Database of Genomic Variants (DGV) for FAM185A Gene

Variant ID Type Subtype PubMed ID
nsv888845 CNV Gain 21882294
dgv23n31 CNV Duplication 19718026
nsv469620 CNV Loss 16826518
nsv888922 CNV Loss 21882294
esv2752138 CNV Loss 17911159
nsv470382 CNV Loss 18288195

Variation tolerance for FAM185A Gene

Gene Damage Index Score: 7.48; 82.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM185A Gene

HapMap Linkage Disequilibrium report
FAM185A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM185A Gene

Disorders for FAM185A Gene

Relevant External Links for FAM185A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM185A

No disorders were found for FAM185A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM185A Gene

Publications for FAM185A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM185A Gene

Sources for FAM185A Gene

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