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Aliases for FAM185A Gene

Aliases for FAM185A Gene

  • Family With Sequence Similarity 185 Member A 2 3 5
  • Family With Sequence Similarity 185, Member A 2

External Ids for FAM185A Gene

Previous GeneCards Identifiers for FAM185A Gene

  • GC07P102177
  • GC07P102389
  • GC07P096751

Summaries for FAM185A Gene

GeneCards Summary for FAM185A Gene

FAM185A (Family With Sequence Similarity 185 Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM185A Gene

Genomics for FAM185A Gene

Regulatory Elements for FAM185A Gene

Enhancers for FAM185A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around FAM185A on UCSC Golden Path with GeneCards custom track

Promoters for FAM185A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for FAM185A Gene

102,748,944 bp from pter
102,912,918 bp from pter
163,975 bases
Plus strand

Genomic View for FAM185A Gene

Genes around FAM185A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM185A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM185A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM185A Gene

Proteins for FAM185A Gene

  • Protein details for FAM185A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM185A
    Protein Accession:
    Secondary Accessions:
    • A8MUR7
    • B4DQD3
    • C9IZ91

    Protein attributes for FAM185A Gene

    392 amino acids
    Molecular mass:
    42301 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM185A Gene


neXtProt entry for FAM185A Gene

Post-translational modifications for FAM185A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM185A Gene

No data available for DME Specific Peptides for FAM185A Gene

Domains & Families for FAM185A Gene

Protein Domains for FAM185A Gene


Suggested Antigen Peptide Sequences for FAM185A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM185A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FAM185A Gene

Function for FAM185A Gene

Phenotypes for FAM185A Gene

GenomeRNAi human phenotypes for FAM185A:
genes like me logo Genes that share phenotypes with FAM185A: view

Animal Model Products

CRISPR Products

miRNA for FAM185A Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM185A Gene

Localization for FAM185A Gene

Subcellular locations from

Jensen Localization Image for FAM185A Gene COMPARTMENTS Subcellular localization image for FAM185A gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FAM185A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with FAM185A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM185A Gene

Pathways & Interactions for FAM185A Gene

SuperPathways for FAM185A Gene

No Data Available

Interacting Proteins for FAM185A Gene

Gene Ontology (GO) - Biological Process for FAM185A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM185A Gene

Drugs & Compounds for FAM185A Gene

No Compound Related Data Available

Transcripts for FAM185A Gene

Unigene Clusters for FAM185A Gene

Family with sequence similarity 185, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM185A Gene

No ASD Table

Relevant External Links for FAM185A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM185A Gene

mRNA expression in normal human tissues for FAM185A Gene

Protein differential expression in normal tissues from HIPED for FAM185A Gene

This gene is overexpressed in Heart (29.5), Peripheral blood mononuclear cells (24.2), and Liver (10.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FAM185A Gene

Protein tissue co-expression partners for FAM185A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM185A Gene:


SOURCE GeneReport for Unigene cluster for FAM185A Gene:

genes like me logo Genes that share expression patterns with FAM185A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM185A Gene

Orthologs for FAM185A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM185A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM185A 34
  • 87.21 (n)
  • 79.9 (a)
FAM185A 35
  • 78 (a)
(Canis familiaris)
Mammalia FAM185A 34
  • 86.15 (n)
  • 77.23 (a)
FAM185A 35
  • 77 (a)
(Mus musculus)
Mammalia Fam185a 34
  • 79.78 (n)
  • 74.39 (a)
Fam185a 16
Fam185a 35
  • 72 (a)
(Pan troglodytes)
Mammalia FAM185A 34
  • 99.4 (n)
  • 98.98 (a)
FAM185A 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam185a 34
  • 75.5 (n)
  • 69 (a)
(Monodelphis domestica)
Mammalia FAM185A 35
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia FAM185A 35
  • 49 (a)
(Gallus gallus)
Aves FAM185A 34
  • 68.45 (n)
  • 59.55 (a)
FAM185A 35
  • 60 (a)
(Anolis carolinensis)
Reptilia FAM185A 35
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam185a 34
  • 62.13 (n)
  • 50.3 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.4927 34
(Danio rerio)
Actinopterygii LOC100332968 34
  • 50.66 (n)
  • 39.76 (a)
FAM185A 35
  • 36 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8187 35
  • 19 (a)
Species where no ortholog for FAM185A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM185A Gene

Gene Tree for FAM185A (if available)
Gene Tree for FAM185A (if available)

Paralogs for FAM185A Gene Pseudogenes for FAM185A Gene

genes like me logo Genes that share paralogs with FAM185A: view

No data available for Paralogs for FAM185A Gene

Variants for FAM185A Gene

Sequence variations from dbSNP and Humsavar for FAM185A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
VAR_039356 -

Structural Variations from Database of Genomic Variants (DGV) for FAM185A Gene

Variant ID Type Subtype PubMed ID
dgv23n31 CNV gain 19718026
dgv6538n100 CNV gain 25217958
dgv6540n100 CNV gain 25217958
dgv6541n100 CNV gain 25217958
dgv6543n100 CNV loss 25217958
esv2752138 CNV loss 17911159
esv2761100 CNV gain+loss 21179565
esv3614357 CNV gain 21293372
esv3614358 CNV gain 21293372
nsv1034233 CNV loss 25217958
nsv1153843 CNV duplication 26484159
nsv469620 CNV loss 16826518
nsv470382 CNV loss 18288195
nsv608057 CNV loss 21841781
nsv966870 CNV duplication 23825009
nsv966871 CNV duplication 23825009
nsv970564 CNV duplication 23825009

Variation tolerance for FAM185A Gene

Gene Damage Index Score: 7.48; 82.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM185A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM185A Gene

Disorders for FAM185A Gene

Relevant External Links for FAM185A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM185A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM185A Gene

Publications for FAM185A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 65
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 65
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65

Products for FAM185A Gene

Sources for FAM185A Gene

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