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Aliases for FAM185A Gene

Aliases for FAM185A Gene

  • Family With Sequence Similarity 185, Member A 2 3

External Ids for FAM185A Gene

Previous GeneCards Identifiers for FAM185A Gene

  • GC07P102177
  • GC07P102389
  • GC07P096751

Summaries for FAM185A Gene

GeneCards Summary for FAM185A Gene

FAM185A (Family With Sequence Similarity 185, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM185A Gene

Genomics for FAM185A Gene

Regulatory Elements for FAM185A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM185A Gene

102,748,949 bp from pter
102,850,008 bp from pter
101,060 bases
Plus strand

Genomic View for FAM185A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM185A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM185A Gene

Proteins for FAM185A Gene

  • Protein details for FAM185A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM185A
    Protein Accession:
    Secondary Accessions:
    • A8MUR7
    • B4DQD3
    • C9IZ91

    Protein attributes for FAM185A Gene

    392 amino acids
    Molecular mass:
    42301 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM185A Gene


neXtProt entry for FAM185A Gene

Proteomics data for FAM185A Gene at MOPED

Post-translational modifications for FAM185A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM185A Gene

No data available for DME Specific Peptides for FAM185A Gene

Domains for FAM185A Gene

Protein Domains for FAM185A Gene


Suggested Antigen Peptide Sequences for FAM185A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM185A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FAM185A Gene

Function for FAM185A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM185A Gene

Localization for FAM185A Gene

Subcellular locations from

Jensen Localization Image for FAM185A Gene COMPARTMENTS Subcellular localization image for FAM185A gene
Compartment Confidence
cytosol 4
nucleus 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FAM185A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with FAM185A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM185A Gene

Pathways for FAM185A Gene

SuperPathways for FAM185A Gene

No Data Available

Interacting Proteins for FAM185A Gene

Gene Ontology (GO) - Biological Process for FAM185A Gene


No data available for Pathways by source for FAM185A Gene

Transcripts for FAM185A Gene

Unigene Clusters for FAM185A Gene

Family with sequence similarity 185, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM185A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM185A Gene

No ASD Table

Relevant External Links for FAM185A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM185A Gene

mRNA expression in normal human tissues for FAM185A Gene

Protein differential expression in normal tissues for FAM185A Gene

This gene is overexpressed in Heart (29.5), Peripheral blood mononuclear cells (24.2), and Liver (10.0).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for FAM185A Gene

SOURCE GeneReport for Unigene cluster for FAM185A Gene Hs.202543

genes like me logo Genes that share expressions with FAM185A: view

Expression partners for FAM185A Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM185A Gene

Orthologs for FAM185A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM185A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM185A 35
  • 87.21 (n)
  • 79.9 (a)
FAM185A 36
  • 78 (a)
(Canis familiaris)
Mammalia FAM185A 35
  • 86.15 (n)
  • 77.23 (a)
FAM185A 36
  • 77 (a)
(Mus musculus)
Mammalia Fam185a 35
  • 79.78 (n)
  • 74.39 (a)
Fam185a 16
Fam185a 36
  • 72 (a)
(Pan troglodytes)
Mammalia FAM185A 35
  • 99.4 (n)
  • 98.98 (a)
FAM185A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam185a 35
  • 75.5 (n)
  • 69 (a)
(Monodelphis domestica)
Mammalia FAM185A 36
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia FAM185A 36
  • 49 (a)
(Gallus gallus)
Aves FAM185A 35
  • 68.45 (n)
  • 59.55 (a)
FAM185A 36
  • 60 (a)
(Anolis carolinensis)
Reptilia FAM185A 36
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam185a 35
  • 62.13 (n)
  • 50.3 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.4927 35
(Danio rerio)
Actinopterygii LOC100332968 35
  • 50.66 (n)
  • 39.76 (a)
FAM185A 36
  • 36 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8187 36
  • 19 (a)
Species with no ortholog for FAM185A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM185A Gene

Gene Tree for FAM185A (if available)
Gene Tree for FAM185A (if available)

Paralogs for FAM185A Gene Pseudogenes for FAM185A Gene

genes like me logo Genes that share paralogs with FAM185A: view

No data available for Paralogs for FAM185A Gene

Variants for FAM185A Gene

Sequence variations from dbSNP and Humsavar for FAM185A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1029914 -- 102,753,626(-) caatc(A/G)ttctc intron-variant
rs2261257 -- 102,771,914(-) GATAG(A/G)AATAA intron-variant
rs2430066 -- 102,797,078(-) AGTTT(C/T)AATGA intron-variant
rs2430067 -- 102,796,988(-) AAGTA(C/T)ACAAT intron-variant
rs2430068 -- 102,796,957(-) ATAAT(A/C)GTAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM185A Gene

Variant ID Type Subtype PubMed ID
nsv888845 CNV Gain 21882294
dgv23n31 CNV Duplication 19718026
nsv469620 CNV Loss 16826518
nsv888922 CNV Loss 21882294
esv2752138 CNV Loss 17911159
nsv470382 CNV Loss 18288195

Relevant External Links for FAM185A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM185A Gene

Disorders for FAM185A Gene

No disorders were found for FAM185A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM185A Gene

Publications for FAM185A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4

Products for FAM185A Gene

Sources for FAM185A Gene

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