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Aliases for FAM184B Gene

Aliases for FAM184B Gene

  • Family With Sequence Similarity 184 Member B 2 3 5
  • Family With Sequence Similarity 184, Member B 2
  • KIAA1276 4

External Ids for FAM184B Gene

Previous GeneCards Identifiers for FAM184B Gene

  • GC04M017242
  • GC04M016988

Summaries for FAM184B Gene

GeneCards Summary for FAM184B Gene

FAM184B (Family With Sequence Similarity 184 Member B) is a Protein Coding gene. An important paralog of this gene is FAM184A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM184B Gene

Genomics for FAM184B Gene

Regulatory Elements for FAM184B Gene

Enhancers for FAM184B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM184B on UCSC Golden Path with GeneCards custom track

Promoters for FAM184B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM184B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM184B Gene

Chromosome:
4
Start:
17,629,306 bp from pter
End:
17,781,527 bp from pter
Size:
152,222 bases
Orientation:
Minus strand

Genomic View for FAM184B Gene

Genes around FAM184B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM184B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM184B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM184B Gene

Proteins for FAM184B Gene

  • Protein details for FAM184B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9ULE4-F184B_HUMAN
    Recommended name:
    Protein FAM184B
    Protein Accession:
    Q9ULE4

    Protein attributes for FAM184B Gene

    Size:
    1060 amino acids
    Molecular mass:
    121044 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA86590.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for FAM184B Gene

Proteomics data for FAM184B Gene at MOPED

Post-translational modifications for FAM184B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM184B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM184B Gene

Domains & Families for FAM184B Gene

Protein Domains for FAM184B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM184B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9ULE4

UniProtKB/Swiss-Prot:

F184B_HUMAN :
  • Belongs to the FAM184 family.
Family:
  • Belongs to the FAM184 family.
genes like me logo Genes that share domains with FAM184B: view

No data available for Gene Families for FAM184B Gene

Function for FAM184B Gene

Phenotypes for FAM184B Gene

genes like me logo Genes that share phenotypes with FAM184B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM184B Gene

Localization for FAM184B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM184B Gene COMPARTMENTS Subcellular localization image for FAM184B gene
Compartment Confidence
cytosol 2
nucleus 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM184B Gene

Pathways & Interactions for FAM184B Gene

SuperPathways for FAM184B Gene

No Data Available

Interacting Proteins for FAM184B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000265018%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000265018 Q9ULE4-F184B_HUMAN for FAM184B Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM184B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM184B Gene

Drugs & Compounds for FAM184B Gene

No Compound Related Data Available

Transcripts for FAM184B Gene

mRNA/cDNA for FAM184B Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(25) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM184B Gene

Family with sequence similarity 184, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM184B Gene

No ASD Table

Relevant External Links for FAM184B Gene

GeneLoc Exon Structure for
FAM184B
ECgene alternative splicing isoforms for
FAM184B

Expression for FAM184B Gene

mRNA expression in normal human tissues for FAM184B Gene

Protein differential expression in normal tissues from HIPED for FAM184B Gene

This gene is overexpressed in Fetal testis (40.9), Bone (12.4), and Liver, secretome (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for FAM184B Gene



SOURCE GeneReport for Unigene cluster for FAM184B Gene Hs.744951

genes like me logo Genes that share expression patterns with FAM184B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM184B Gene

Orthologs for FAM184B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM184B Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia FAM184B 35
  • 87.23 (n)
  • 85.28 (a)
FAM184B 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM184B 35
  • 98.36 (n)
  • 97.58 (a)
FAM184B 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM184B 36
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM184B 36
  • 57 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam184b 36
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM184B 36
  • 44 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM184B 35
  • 57.85 (n)
  • 48.08 (a)
FAM184B 36
  • 31 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM184B 36
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488800 35
  • 53.51 (n)
  • 40.03 (a)
zebrafish
(Danio rerio)
Actinopterygii fam184b 36
  • 23 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea tag-278 36
  • 12 (a)
OneToMany
Species with no ortholog for FAM184B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM184B Gene

ENSEMBL:
Gene Tree for FAM184B (if available)
TreeFam:
Gene Tree for FAM184B (if available)

Paralogs for FAM184B Gene

Paralogs for FAM184B Gene

genes like me logo Genes that share paralogs with FAM184B: view

Variants for FAM184B Gene

Sequence variations from dbSNP and Humsavar for FAM184B Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs16895365 - 17,635,043(+) GAGGA(C/T)TGAAA reference, missense
rs6825562 - 17,632,590(+) GCTGG(A/G)CTTCT reference, missense
rs16343 -- 17,633,937(-) AATGC(-/TTTAT)TTTGT intron-variant
rs979822 -- 17,698,695(-) tagag(C/T)agaat intron-variant
rs979823 -- 17,698,553(-) GTTGA(C/T)TCTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM184B Gene

Variant ID Type Subtype PubMed ID
esv997752 CNV Deletion 20482838
nsv527339 CNV Loss 19592680
nsv878721 CNV Loss 21882294
nsv289646 CNV Loss 16902084
esv271490 CNV Insertion 20981092
esv272317 CNV Insertion 20981092

Variation tolerance for FAM184B Gene

Gene Damage Index Score: 5.37; 70.97% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM184B Gene

Disorders for FAM184B Gene

Relevant External Links for FAM184B

Genetic Association Database (GAD)
FAM184B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM184B

No disorders were found for FAM184B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM184B Gene

Publications for FAM184B Gene

  1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4 67
  2. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. (PMID: 25429064) He M. … Qi L. (Hum. Mol. Genet. 2015) 3
  3. Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X. … Seielstad M. (PLoS ONE 2013) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for FAM184B Gene

Sources for FAM184B Gene

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