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Aliases for FAM184B Gene

Aliases for FAM184B Gene

  • Family With Sequence Similarity 184 Member B 2 3 5
  • Family With Sequence Similarity 184, Member B 2
  • KIAA1276 4

External Ids for FAM184B Gene

Previous GeneCards Identifiers for FAM184B Gene

  • GC04M017242
  • GC04M016988

Summaries for FAM184B Gene

GeneCards Summary for FAM184B Gene

FAM184B (Family With Sequence Similarity 184 Member B) is a Protein Coding gene. An important paralog of this gene is FAM184A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM184B Gene

Genomics for FAM184B Gene

Regulatory Elements for FAM184B Gene

Enhancers for FAM184B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F017640 0.9 FANTOM5 10.9 +141.0 140986 0.0 LAP3 FAM184B CLRN2 GC04P017652 PIR38754
GH04F017636 0.2 ENCODE 10.9 +144.8 144753 0.8 CTCF ZNF654 TRIM22 ZNF384 REST ZNF48 ZIC2 RAD21 SMARCA4 POLR2A LAP3 FAM184B GC04P017652 PIR38754
GH04F017623 0.2 ENCODE 9.7 +157.9 157915 0.2 LAP3 DCAF16 NCAPG FAM184B PIR38754 GC04P017652
GH04F017624 0.7 ENCODE 9.7 +156.5 156515 0.2 LAP3 DCAF16 NCAPG FAM184B PIR38754 GC04P017652
GH04F017781 0.6 Ensembl 0.8 +0.0 27 1.0 ZNF202 ZNF687 RNF2 BHLHE40 ZBTB8A ZIC2 ZFHX2 ZBTB26 EZH2 EGR2 DCAF16 MED28 FAM184B GC04M017719
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around FAM184B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM184B Gene

17,629,306 bp from pter
17,781,527 bp from pter
152,222 bases
Minus strand

Genomic View for FAM184B Gene

Genes around FAM184B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM184B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM184B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM184B Gene

Proteins for FAM184B Gene

  • Protein details for FAM184B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM184B
    Protein Accession:

    Protein attributes for FAM184B Gene

    1060 amino acids
    Molecular mass:
    121044 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA86590.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for FAM184B Gene

Post-translational modifications for FAM184B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM184B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM184B Gene

Domains & Families for FAM184B Gene

Protein Domains for FAM184B Gene


Suggested Antigen Peptide Sequences for FAM184B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM184 family.
  • Belongs to the FAM184 family.
genes like me logo Genes that share domains with FAM184B: view

No data available for Gene Families for FAM184B Gene

Function for FAM184B Gene

Phenotypes for FAM184B Gene

genes like me logo Genes that share phenotypes with FAM184B: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM184B Gene

Localization for FAM184B Gene

Subcellular locations from

Jensen Localization Image for FAM184B Gene COMPARTMENTS Subcellular localization image for FAM184B gene
Compartment Confidence
cytosol 2
nucleus 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM184B Gene

Pathways & Interactions for FAM184B Gene

SuperPathways for FAM184B Gene

No Data Available

Interacting Proteins for FAM184B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000265018 Q9ULE4-F184B_HUMAN for FAM184B Gene via STRING IID

Gene Ontology (GO) - Biological Process for FAM184B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM184B Gene

Transcripts for FAM184B Gene

mRNA/cDNA for FAM184B Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(25) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM184B Gene

Family with sequence similarity 184, member B:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM184B Gene

No ASD Table

Relevant External Links for FAM184B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM184B Gene

mRNA expression in normal human tissues for FAM184B Gene

Protein differential expression in normal tissues from HIPED for FAM184B Gene

This gene is overexpressed in Fetal testis (40.9), Bone (12.4), and Liver, secretome (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FAM184B Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM184B Gene:


SOURCE GeneReport for Unigene cluster for FAM184B Gene:

genes like me logo Genes that share expression patterns with FAM184B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM184B Gene

Orthologs for FAM184B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM184B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM184B 34 35
  • 98.36 (n)
(Canis familiaris)
Mammalia FAM184B 34 35
  • 87.23 (n)
(Bos Taurus)
Mammalia FAM184B 35
  • 82 (a)
(Mus musculus)
Mammalia Fam184b 35
  • 75 (a)
(Monodelphis domestica)
Mammalia FAM184B 35
  • 57 (a)
(Ornithorhynchus anatinus)
Mammalia FAM184B 35
  • 44 (a)
(Gallus gallus)
Aves FAM184B 34 35
  • 57.85 (n)
(Anolis carolinensis)
Reptilia FAM184B 35
  • 39 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488800 34
  • 53.51 (n)
(Danio rerio)
Actinopterygii fam184b 35
  • 23 (a)
(Caenorhabditis elegans)
Secernentea tag-278 35
  • 12 (a)
Species where no ortholog for FAM184B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM184B Gene

Gene Tree for FAM184B (if available)
Gene Tree for FAM184B (if available)

Paralogs for FAM184B Gene

Paralogs for FAM184B Gene

genes like me logo Genes that share paralogs with FAM184B: view

Variants for FAM184B Gene

Sequence variations from dbSNP and Humsavar for FAM184B Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs10002848 -- 17,669,572(+) CTAAT(A/G)AGACC intron-variant
rs10006317 -- 17,700,902(+) TTTGG(A/G)AATTG intron-variant
rs10009541 -- 17,680,595(+) TCAAC(C/T)CAATT intron-variant
rs10009933 -- 17,668,484(+) TTGAA(G/T)TTCCC intron-variant
rs10011865 -- 17,644,087(+) GCGAA(A/G)GCCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM184B Gene

Variant ID Type Subtype PubMed ID
esv3307214 CNV mobile element insertion 20981092
esv3308043 CNV mobile element insertion 20981092
esv3348759 CNV insertion 20981092
esv3361618 CNV insertion 20981092
esv3373372 CNV insertion 20981092
esv3599781 CNV loss 21293372
esv3599782 CNV gain 21293372
esv997752 CNV deletion 20482838
nsv1006981 CNV loss 25217958
nsv289646 CNV deletion 16902084
nsv476179 CNV novel sequence insertion 20440878
nsv527339 CNV loss 19592680
nsv949806 CNV duplication 24416366

Variation tolerance for FAM184B Gene

Gene Damage Index Score: 5.37; 70.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM184B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM184B Gene

Disorders for FAM184B Gene

Relevant External Links for FAM184B

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM184B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM184B Gene

Publications for FAM184B Gene

  1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4 64
  2. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. (PMID: 25429064) He M. … Qi L. (Hum. Mol. Genet. 2015) 3 64
  3. Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X. … Seielstad M. (PLoS ONE 2013) 3 64
  4. A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. (PMID: 20189936) Okada Y. … Kamatani N. (Hum. Mol. Genet. 2010) 46 64
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64

Products for FAM184B Gene

Sources for FAM184B Gene

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