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Aliases for FAM184A Gene

Aliases for FAM184A Gene

  • Family With Sequence Similarity 184, Member A 2 3
  • C6orf60 3 4
  • Chromosome 6 Open Reading Frame 60 2
  • Protein FAM184A 3

External Ids for FAM184A Gene

Previous Symbols for FAM184A Gene

  • C6orf60

Summaries for FAM184A Gene

GeneCards Summary for FAM184A Gene

FAM184A (Family With Sequence Similarity 184, Member A) is a Protein Coding gene. An important paralog of this gene is FAM184B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM184A Gene

Genomics for FAM184A Gene

Genomic Location for FAM184A Gene

Start:
118,959,763 bp from pter
End:
119,149,387 bp from pter
Size:
189,625 bases
Orientation:
Minus strand

Genomic View for FAM184A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM184A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM184A Gene

Regulatory Elements for FAM184A Gene

Proteins for FAM184A Gene

  • Protein details for FAM184A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NB25-F184A_HUMAN
    Recommended name:
    Protein FAM184A
    Protein Accession:
    Q8NB25
    Secondary Accessions:
    • B9DI75
    • F8W8D6
    • Q5TBS9
    • Q7Z323
    • Q96GY8
    • Q9H0J8
    • Q9H851

    Protein attributes for FAM184A Gene

    Size:
    1140 amino acids
    Molecular mass:
    132965 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14769.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC03719.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM184A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM184A Gene

Proteomics data for FAM184A Gene at MOPED

Post-translational modifications for FAM184A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys1110

No data available for DME Specific Peptides for FAM184A Gene

Domains for FAM184A Gene

Protein Domains for FAM184A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F184A_HUMAN
Family:
  • Belongs to the FAM184 family.:
    • Q8NB25
genes like me logo Genes that share domains with FAM184A: view

No data available for Gene Families for FAM184A Gene

Function for FAM184A Gene

Gene Ontology (GO) - Molecular Function for FAM184A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 24407287
genes like me logo Genes that share ontologies with FAM184A: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM184A Gene

Localization for FAM184A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM184A Gene COMPARTMENTS Subcellular localization image for FAM184A gene
Compartment Confidence
cytosol 2
nucleus 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for FAM184A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
genes like me logo Genes that share ontologies with FAM184A: view

Pathways for FAM184A Gene

SuperPathways for FAM184A Gene

No Data Available

Interacting Proteins for FAM184A Gene

Gene Ontology (GO) - Biological Process for FAM184A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with FAM184A: view

No data available for Pathways by source for FAM184A Gene

Transcripts for FAM184A Gene

Unigene Clusters for FAM184A Gene

Family with sequence similarity 184, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM184A Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b · 18c · 18d ^
SP1: - - -
SP2: - - - - -
SP3: - - - - - - -
SP4: - -
SP5:
SP6: - -
SP7:

ExUns: 19 ^ 20
SP1: -
SP2: -
SP3: -
SP4:
SP5:
SP6: -
SP7: -

Relevant External Links for FAM184A Gene

GeneLoc Exon Structure for
FAM184A
ECgene alternative splicing isoforms for
FAM184A

Expression for FAM184A Gene

mRNA expression in normal human tissues for FAM184A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM184A Gene

SOURCE GeneReport for Unigene cluster for FAM184A Gene Hs.443789

genes like me logo Genes that share expressions with FAM184A: view

Orthologs for FAM184A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM184A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM184A 36
  • 99.71 (n)
  • 99.56 (a)
FAM184A 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM184A 36
  • 91.96 (n)
  • 94.51 (a)
FAM184A 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM184A 36
  • 93.25 (n)
  • 94.21 (a)
FAM184A 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam184a 36
  • 86.02 (n)
  • 88.95 (a)
Fam184a 16
Fam184a 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM184A 37
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 77 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
-- 37
  • 84 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam184a 36
  • 83.63 (n)
  • 87.85 (a)
chicken
(Gallus gallus)
Aves FAM184A 36
  • 79.2 (n)
  • 80.9 (a)
FAM184A 37
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM184A 37
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam184a 36
  • 70.95 (n)
  • 69.37 (a)
Str.19321 36
zebrafish
(Danio rerio)
Actinopterygii fam184a 37
  • 57 (a)
OneToMany
FAM184A (1 of 2) 37
  • 52 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea tag-278 37
  • 18 (a)
OneToMany
Species with no ortholog for FAM184A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM184A Gene

ENSEMBL:
Gene Tree for FAM184A (if available)
TreeFam:
Gene Tree for FAM184A (if available)

Paralogs for FAM184A Gene

Paralogs for FAM184A Gene

Selected SIMAP similar genes for FAM184A Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with FAM184A: view

Variants for FAM184A Gene

Sequence variations from dbSNP and Humsavar for FAM184A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs586708 -- 119,050,203(+) gagaa(A/G)aggga intron-variant
rs589865 -- 119,050,899(+) aggaa(A/G)agaaa intron-variant
rs590004 -- 119,052,034(+) CTGAA(C/T)ATCTC intron-variant
rs591328 -- 119,076,839(-) AGGAA(A/G)ATCTA intron-variant
rs593386 -- 119,136,006(+) gggcg(C/T)ggtgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM184A Gene

Variant ID Type Subtype PubMed ID
esv1571689 CNV Insertion 17803354
esv2666219 CNV Deletion 23128226
nsv528632 CNV Loss 19592680
esv270541 CNV Insertion 20981092
esv273077 CNV Insertion 20981092
esv2763 CNV Deletion 18987735
esv2732625 CNV Deletion 23290073
nsv349001 CNV Loss 16902084
esv7449 CNV Loss 19470904
esv1008585 CNV Deletion 20482838
esv1686491 CNV Deletion 17803354
esv272161 CNV Insertion 20981092
esv269182 CNV Insertion 20981092
esv2524990 CNV Deletion 19546169
esv1958583 CNV Deletion 18987734
esv2670982 CNV Deletion 23128226
nsv886570 CNV Gain 21882294

Relevant External Links for FAM184A Gene

HapMap Linkage Disequilibrium report
FAM184A

Disorders for FAM184A Gene

Relevant External Links for FAM184A

Genetic Association Database (GAD)
FAM184A
Human Genome Epidemiology (HuGE) Navigator
FAM184A
genes like me logo Genes that share disorders with FAM184A: view

No data available for UniProtKB/Swiss-Prot for FAM184A Gene

Publications for FAM184A Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for FAM184A Gene

Sources for FAM184A Gene

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