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Aliases for FAM184A Gene

Aliases for FAM184A Gene

  • Family With Sequence Similarity 184 Member A 2 3 5
  • Family With Sequence Similarity 184, Member A 2 3
  • C6orf60 3 4
  • Chromosome 6 Open Reading Frame 60 2

External Ids for FAM184A Gene

Previous HGNC Symbols for FAM184A Gene

  • C6orf60

Previous GeneCards Identifiers for FAM184A Gene

  • GC06M119323
  • GC06M116863
  • GC06M119280

Summaries for FAM184A Gene

GeneCards Summary for FAM184A Gene

FAM184A (Family With Sequence Similarity 184 Member A) is a Protein Coding gene. An important paralog of this gene is FAM184B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM184A Gene

Genomics for FAM184A Gene

Regulatory Elements for FAM184A Gene

Enhancers for FAM184A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM184A on UCSC Golden Path with GeneCards custom track

Promoters for FAM184A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM184A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM184A Gene

118,959,763 bp from pter
119,149,387 bp from pter
189,625 bases
Minus strand

Genomic View for FAM184A Gene

Genes around FAM184A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM184A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM184A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM184A Gene

Proteins for FAM184A Gene

  • Protein details for FAM184A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM184A
    Protein Accession:
    Secondary Accessions:
    • B9DI75
    • F8W8D6
    • Q5TBS9
    • Q7Z323
    • Q96GY8
    • Q9H0J8
    • Q9H851

    Protein attributes for FAM184A Gene

    1140 amino acids
    Molecular mass:
    132965 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14769.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC03719.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM184A Gene


neXtProt entry for FAM184A Gene

Proteomics data for FAM184A Gene at MOPED

Post-translational modifications for FAM184A Gene

  • Ubiquitination at Lys 1110
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for FAM184A Gene

Domains & Families for FAM184A Gene

Protein Domains for FAM184A Gene


Suggested Antigen Peptide Sequences for FAM184A Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM184 family.
  • Belongs to the FAM184 family.
genes like me logo Genes that share domains with FAM184A: view

No data available for Gene Families for FAM184A Gene

Function for FAM184A Gene

genes like me logo Genes that share phenotypes with FAM184A: view

Animal Model Products

CRISPR Products

miRNA for FAM184A Gene

miRTarBase miRNAs that target FAM184A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM184A Gene

Localization for FAM184A Gene

Subcellular locations from

Jensen Localization Image for FAM184A Gene COMPARTMENTS Subcellular localization image for FAM184A gene
Compartment Confidence
extracellular 5
cytosol 3
cytoskeleton 2
nucleus 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM184A Gene

Pathways & Interactions for FAM184A Gene

SuperPathways for FAM184A Gene

No Data Available

Interacting Proteins for FAM184A Gene

Gene Ontology (GO) - Biological Process for FAM184A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM184A Gene

Drugs & Compounds for FAM184A Gene

No Compound Related Data Available

Transcripts for FAM184A Gene

Unigene Clusters for FAM184A Gene

Family with sequence similarity 184, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM184A Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b · 18c · 18d ^
SP1: - - -
SP2: - - - - -
SP3: - - - - - - -
SP4: - -
SP6: - -

ExUns: 19 ^ 20
SP1: -
SP2: -
SP3: -
SP6: -
SP7: -

Relevant External Links for FAM184A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM184A Gene

mRNA expression in normal human tissues for FAM184A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for FAM184A Gene

This gene is overexpressed in Synovial fluid (28.7), Bone (22.0), and Plasma (9.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM184A Gene

SOURCE GeneReport for Unigene cluster for FAM184A Gene Hs.443789

genes like me logo Genes that share expression patterns with FAM184A: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM184A Gene

Orthologs for FAM184A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM184A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM184A 35
  • 91.96 (n)
  • 94.51 (a)
FAM184A 36
  • 93 (a)
(Canis familiaris)
Mammalia FAM184A 35
  • 93.25 (n)
  • 94.21 (a)
FAM184A 36
  • 94 (a)
(Mus musculus)
Mammalia Fam184a 35
  • 86.02 (n)
  • 88.95 (a)
Fam184a 16
Fam184a 36
  • 89 (a)
(Pan troglodytes)
Mammalia FAM184A 35
  • 99.71 (n)
  • 99.56 (a)
FAM184A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam184a 35
  • 83.63 (n)
  • 87.85 (a)
(Monodelphis domestica)
Mammalia FAM184A 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 77 (a)
-- 36
  • 81 (a)
-- 36
  • 84 (a)
(Gallus gallus)
Aves FAM184A 35
  • 79.2 (n)
  • 80.9 (a)
FAM184A 36
  • 77 (a)
(Anolis carolinensis)
Reptilia FAM184A 36
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam184a 35
  • 70.95 (n)
  • 69.37 (a)
Str.19321 35
(Danio rerio)
Actinopterygii fam184a 36
  • 57 (a)
FAM184A (1 of 2) 36
  • 52 (a)
(Caenorhabditis elegans)
Secernentea tag-278 36
  • 18 (a)
Species with no ortholog for FAM184A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM184A Gene

Gene Tree for FAM184A (if available)
Gene Tree for FAM184A (if available)

Paralogs for FAM184A Gene

Paralogs for FAM184A Gene

genes like me logo Genes that share paralogs with FAM184A: view

Variants for FAM184A Gene

Sequence variations from dbSNP and Humsavar for FAM184A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs34681930 - 119,024,451(-) GGACA(A/C/G)CTTCA reference, synonymous-codon, missense
rs34977570 - 119,024,443(-) TCAAG(G/T)ACAGT reference, missense
rs17827619 - 119,006,467(+) AGCAT(C/T)CTTGG reference, missense
rs1068588 -- 119,049,166(+) acata(C/G)gccag intron-variant
rs1068680 -- 119,133,849(+) acaag(A/G)tctca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM184A Gene

Variant ID Type Subtype PubMed ID
esv1571689 CNV Insertion 17803354
esv2666219 CNV Deletion 23128226
nsv528632 CNV Loss 19592680
esv270541 CNV Insertion 20981092
esv273077 CNV Insertion 20981092
esv2763 CNV Deletion 18987735
esv2732625 CNV Deletion 23290073
nsv349001 CNV Loss 16902084
esv7449 CNV Loss 19470904
esv1008585 CNV Deletion 20482838
esv1686491 CNV Deletion 17803354
esv272161 CNV Insertion 20981092
esv269182 CNV Insertion 20981092
esv2524990 CNV Deletion 19546169
esv1958583 CNV Deletion 18987734
esv2670982 CNV Deletion 23128226
nsv886570 CNV Gain 21882294

Variation tolerance for FAM184A Gene

Residual Variation Intolerance Score: 35.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.32; 70.62% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM184A Gene

Disorders for FAM184A Gene

Relevant External Links for FAM184A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM184A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM184A Gene

Publications for FAM184A Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Promyelocytic Leukemia protein (PML) interacts with ASC to limit Inflammasome Activation. (PMID: 24407287) Dowling J.K. … O'Neill L.A. (J. Biol. Chem. 2014) 3
  4. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. (PMID: 25184681) Hill S.J. … Livingston D.M. (Genes Dev. 2014) 3
  5. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. (PMID: 25260751) Charlaftis N. … Gallagher E. (EMBO J. 2014) 3

Products for FAM184A Gene

Sources for FAM184A Gene