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Aliases for FAM183A Gene

Aliases for FAM183A Gene

  • Family With Sequence Similarity 183 Member A 2 3 5
  • Family With Sequence Similarity 183, Member A 2
  • Protein FAM183A 3
  • HCG23177 3

External Ids for FAM183A Gene

Previous GeneCards Identifiers for FAM183A Gene

  • GC01P043383
  • GC01P043610
  • GC01P041733

Summaries for FAM183A Gene

GeneCards Summary for FAM183A Gene

FAM183A (Family With Sequence Similarity 183 Member A) is a Protein Coding gene.

Additional gene information for FAM183A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM183A Gene

Genomics for FAM183A Gene

Regulatory Elements for FAM183A Gene

Enhancers for FAM183A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H043120 1.2 Ensembl ENCODE 24.8 -21.7 -21700 1 ATF1 FEZF1 ZNF2 ZNF121 FOS KLF7 ATF7 SP3 YY2 REST FAM183A CFAP57 EBNA1BP2 ENSG00000277513
GH01H043072 1.2 Ensembl ENCODE 16.7 -69.7 -69665 1 HDGF ATF1 ARNT ARID4B ZNF2 ZNF766 ZNF143 ATF7 ZC3H11A NCOA1 FAM183A RNU6-880P CFAP57 ZNF691 ENSG00000228192 EBNA1BP2 RNU6-536P ENSG00000236180 SZT2 GC01P043068
GH01H042923 1.6 Ensembl ENCODE dbSUPER 10 -218.2 -218227 3 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF143 FOXJ3 SZT2 HYI MKRN8P HNRNPFP1 PPIH P3H1 RNU6-880P CCDC30 ZNF691
GH01H043293 1.7 FANTOM5 Ensembl ENCODE dbSUPER 9.4 +152.1 152094 3 HDGF FOXA2 KLF17 RAD21 YY1 ATF7 ETV6 RUNX3 IKZF2 USF2 MED8 EBNA1BP2 MPL LOC105378687 CDC20 ELOVL1 ENSG00000229431 SZT2 FAM183A ATP6V0B
GH01H043069 1 Ensembl ENCODE 15.1 -73.2 -73205 1 SOX13 SAP130 DMAP1 RAD21 ZIC2 TEAD3 ZFHX2 PATZ1 GATAD2A NFIA FAM183A RNU6-880P GC01P043068 ENSG00000277513
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM183A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM183A Gene

43,142,979 bp from pter
43,156,396 bp from pter
13,418 bases
Plus strand

Genomic View for FAM183A Gene

Genes around FAM183A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM183A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM183A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM183A Gene

Proteins for FAM183A Gene

  • Protein details for FAM183A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM183A
    Protein Accession:
    Secondary Accessions:
    • B7ZBL8

    Protein attributes for FAM183A Gene

    134 amino acids
    Molecular mass:
    15996 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM183A Gene

Post-translational modifications for FAM183A Gene

No Post-translational modifications

Other Protein References for FAM183A Gene

No data available for DME Specific Peptides for FAM183A Gene

Domains & Families for FAM183A Gene

Gene Families for FAM183A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM183A Gene


Suggested Antigen Peptide Sequences for FAM183A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM183 family.
  • Belongs to the FAM183 family.
genes like me logo Genes that share domains with FAM183A: view

Function for FAM183A Gene

Phenotypes From GWAS Catalog for FAM183A Gene

genes like me logo Genes that share phenotypes with FAM183A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for FAM183A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM183A Gene

Localization for FAM183A Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM183A gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM183A Gene

Pathways & Interactions for FAM183A Gene

SuperPathways for FAM183A Gene

No Data Available

Interacting Proteins for FAM183A Gene

Gene Ontology (GO) - Biological Process for FAM183A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM183A Gene

Drugs & Compounds for FAM183A Gene

No Compound Related Data Available

Transcripts for FAM183A Gene

Unigene Clusters for FAM183A Gene

Family with sequence similarity 183, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for FAM183A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for FAM183A Gene

No ASD Table

Relevant External Links for FAM183A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM183A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM183A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM183A Gene

This gene is overexpressed in Fallopian Tube (x7.5), Pituitary (x7.2), Brain - Hypothalamus (x4.3), and Cervix - Endocervix (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of FAM183A Gene:


SOURCE GeneReport for Unigene cluster for FAM183A Gene:


Evidence on tissue expression from TISSUES for FAM183A Gene

  • Nervous system(2.2)
genes like me logo Genes that share expression patterns with FAM183A: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM183A Gene

Orthologs for FAM183A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM183A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM183A 34 33
  • 100 (n)
(Bos Taurus)
Mammalia FAM183A 34
  • 87 (a)
(Mus musculus)
Mammalia Fam183b 34
  • 77 (a)
(Canis familiaris)
Mammalia -- 34
  • 75 (a)
-- 34
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 70 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 69 (a)
(Gallus gallus)
Aves FAM183A 34
  • 53 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 49 (a)
(Danio rerio)
Actinopterygii FAM183B 34
  • 44 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 45 (a)
Species where no ortholog for FAM183A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM183A Gene

Gene Tree for FAM183A (if available)
Gene Tree for FAM183A (if available)

Paralogs for FAM183A Gene

(2) SIMAP similar genes for FAM183A Gene using alignment to 5 proteins: Pseudogenes for FAM183A Gene

genes like me logo Genes that share paralogs with FAM183A: view

No data available for Paralogs for FAM183A Gene

Variants for FAM183A Gene

Sequence variations from dbSNP and Humsavar for FAM183A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000486698 -- 43,151,714(+) TCCCC(G/T)CTACC intron-variant
rs1000669947 -- 43,146,750(+) ATGAA(C/T)GAAGT intron-variant, upstream-variant-2KB
rs1000763138 -- 43,146,658(+) AATCC(A/T)ATTAA intron-variant, upstream-variant-2KB
rs1000928324 -- 43,147,097(+) GCCTC(A/G)GCCTC intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1001192168 -- 43,152,224(+) AATCC(A/G)TCTGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM183A Gene

Variant ID Type Subtype PubMed ID
nsv829693 CNV loss 17160897

Variation tolerance for FAM183A Gene

Residual Variation Intolerance Score: 81.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.06; 21.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM183A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM183A Gene

Disorders for FAM183A Gene

Relevant External Links for FAM183A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM183A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM183A Gene

Publications for FAM183A Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 60
  2. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 2 3 60
  3. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PMID: 18854154) König R … Chanda SK (Cell 2008) 3 60

Products for FAM183A Gene

Sources for FAM183A Gene

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