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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FAM182B Gene

pseudogene GIFtS: 28
GCID: GC20M025744

family with sequence similarity 182, member B

Search for FAM182B
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Family With Sequence Similarity 182, Member B¹ ²

External Ids:	HGNC: 34503¹	Entrez Gene: 728882²	Ensembl: ENSG00000175170⁷	UniProtKB: Q5T319³

ORGUL members:
	NONCODE:n383881

Export aliases for FAM182B gene to outside databases

Previous GC identifer: GC20M025692

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011387.8

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for FAM182B
Other transcription factors

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Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM182B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.1 Ensembl cytogenetic band: 20p11.1 HGNC cytogenetic band: 20p11.1

FAM182B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM182B gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M025744: view genomic region (about GC identifiers)

Start:	25,744,102 bp from pter	End:	25,848,861 bp from pter
Size:	104,760 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: F182B_HUMAN, Q5T319 (See protein sequence)

Recommended Name: Protein FAM182B

Size: 152 amino acids; 15775 Da

Secondary accessions: Q4G0Q1

Alternative splicing: 2 isoforms: Q5T319-1 Q5T319-2 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for FAM182B: NX_Q5T319

FAM182B Protein expression data from MOPED and PaxDb: About this image

ENSEMBL proteins:

ENSP00000365585 ENSP00000464534 ENSP00000365586

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q5T319

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FAM182B

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM182B
Search CenterWatch for drugs/clinical trials and news about FAM182B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for FAM182B:

Family with sequence similarity 182, member B

Hs.682103 [show with all ESTs]

Unigene Representative Sequence: NR_026714

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000478164(uc010zth.1 uc010zti.2) ENST00000453481 ENST00000376403(uc002wve.3)

ENST00000485279 ENST00000584071 ENST00000582267 ENST00000584356 ENST00000376404(uc002wvd.1)

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Additional cDNA sequence:

AK054844.1 AL096727.1 NR_026714.2 NR_027061.2

10 DOTS entries:

DT.208399 DT.120803187 DT.100682559 DT.120803206 DT.70102742 DT.208398 DT.75127200 DT.100689640

DT.92019358 DT.120803226

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAM182B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
See FAM182B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM182B

SOURCE GeneReport for Unigene cluster: Hs.682103

SABiosciences Custom PCR Arrays for FAM182B

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for FAM182B (if available)
TreeFam Gene Tree for FAM182B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FAM182B gene

FAM182A²

1 SIMAP similar gene for FAM182B using alignment to 3 protein entries: F182B_HUMAN (see all proteins):

FAM182A

FAM182B for paralogs About GeneDecksing

4 Pseudogenes.org Pseudogenes for FAM182B
PGOHUM00000236984 PGOHUM00000232767 PGOHUM00000233309 PGOHUM00000260603

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2258302^1,2	C,F	--	25743673(+)	`CTGGGG/AGTCAC`	1	--	ds500¹		2		NA	6
rs78104209^1,2	F	--	25743711(+)	`AATACG/AGAAGT`	1	--	ds500¹		2		NA	6
rs188250682^1,2		--	25743796(+)	`TTCCAA/GTAGAC`	1	--	ds500¹		0	--	--	--	--
rs6115281^1,2	C,	--	25743798(+)	`CCAATA/GGACTC`	1	--	ds500¹		2		NA	4
rs191799124^1,2	C	--	25743832(+)	`GTTGAA/CCCAGT`	1	--	ds500¹		0	--	--	--	--
rs183857247^1,2	C	--	25743841(+)	`GTGAAA/CCATAG`	1	--	ds500¹		0	--	--	--	--
rs4447666^1,2	C,H,	--	25743845(+)	`ACCATA/GGCCAG`	1	--	ds500¹		3		NS EA	298
rs182078362^1,2		--	25743880(+)	`AAGAAA/CAATGA`	1	--	ds500¹		0	--	--	--	--
rs188352865^1,2	C	--	25743928(+)	`TGCACC/TCCCAA`	1	--	ds500¹		0	--	--	--	--
rs192984455^1,2	C	--	25743958(+)	`CATATA/GTACCT`	1	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FAM182B (25744102 - 25848861 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for FAM182B
14 CNVs: 73491 79160 79159 4098 90520 73492 90517 79161 29708 73494 90519 73493 32416 90518
1 Inversion: 37229

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FAM182B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM182B)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 728882	HGNC: 34503	Ensembl:ENSG00000175170	euGenes: HUgn728882	ECgene: FAM182B
H-InvDB: FAM182B

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAM182B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAM182B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FAM182B gene:
Search GeneIP for patents involving FAM182B

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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FAM182B Gene

family with sequence similarity 182, member B

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FAM182B Gene

family with sequence similarity 182, member B

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