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Aliases for FAM182B Gene

Subcategory (RNA class) for FAM182B Gene


Quality Score for this RNA gene is


Aliases for FAM182B Gene

  • Family With Sequence Similarity 182 Member B 2 3 5
  • Family With Sequence Similarity 182, Member B 2

External Ids for FAM182B Gene

Previous GeneCards Identifiers for FAM182B Gene

  • GC20M025692

Summaries for FAM182B Gene

GeneCards Summary for FAM182B Gene

FAM182B (Family With Sequence Similarity 182 Member B) is an RNA Gene, and is affiliated with the ncRNA class.

Additional gene information for FAM182B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM182B Gene

Genomics for FAM182B Gene

Regulatory Elements for FAM182B Gene

Enhancers for FAM182B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20H026009 1 ENCODE 36.6 -141.8 -141786 1.8 HDGF ARID4B SIN3A DMAP1 BRCA1 ZNF2 ZBTB7B TCF12 GLIS2 ZNF143 FAM182B NCOR1P1 ABHD12 NANP NINL ZNF337 LOC100134868 ENSG00000231081
GH20H025987 0.7 Ensembl 49.5 -119.1 -119076 0.6 CTCF ZSCAN18 ZSCAN4 ZNF76 THRB ZEB1 ZNF366 PRDM10 ZNF687 MAZ FAM182B NINL PIR33096 LINC01733
GH20H025857 0.9 FANTOM5 Ensembl 38.1 +9.9 9936 0.7 ATM ZBTB2 NRF1 ZSCAN4 FAM182B ZNF337 PIR36382
GH20H025861 1 FANTOM5 29.9 +6.5 6535 0.2 ELF3 RB1 ARID4B SIN3A DMAP1 DNMT3B RAD21 THAP11 HCFC1 ZBTB2 FAM182B ZNF337 PIR36382
GH20H025853 0.9 Ensembl 30.4 +14.4 14425 1.6 ZFP64 ARID4B SIN3A DMAP1 RAD21 YY1 SLC30A9 MIXL1 THAP11 HCFC1 FAM182B LOC101926935 GC20M025850
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM182B on UCSC Golden Path with GeneCards custom track

Promoters for FAM182B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000135897 -76 600 NRF1

Genomic Locations for FAM182B Gene

Genomic Locations for FAM182B Gene
104,760 bases
Minus strand

Genomic View for FAM182B Gene

Genes around FAM182B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM182B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM182B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM182B Gene

Proteins for FAM182B Gene

  • Protein details for FAM182B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM182B
    Protein Accession:
    Secondary Accessions:
    • Q4G0Q1

    Protein attributes for FAM182B Gene

    152 amino acids
    Molecular mass:
    15775 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM182B Gene


neXtProt entry for FAM182B Gene

Post-translational modifications for FAM182B Gene

No Post-translational modifications

Other Protein References for FAM182B Gene

No data available for DME Specific Peptides for FAM182B Gene

Domains & Families for FAM182B Gene

Gene Families for FAM182B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM182B Gene


Suggested Antigen Peptide Sequences for FAM182B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM182B: view

No data available for UniProtKB/Swiss-Prot for FAM182B Gene

Function for FAM182B Gene

Phenotypes From GWAS Catalog for FAM182B Gene

Phenotypes for FAM182B Gene

GenomeRNAi human phenotypes for FAM182B:
genes like me logo Genes that share phenotypes with FAM182B: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM182B Gene

Localization for FAM182B Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM182B gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM182B Gene

Pathways & Interactions for FAM182B Gene

SuperPathways for FAM182B Gene

No Data Available

Interacting Proteins for FAM182B Gene

Gene Ontology (GO) - Biological Process for FAM182B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM182B Gene

Drugs & Compounds for FAM182B Gene

No Compound Related Data Available

Transcripts for FAM182B Gene

mRNA/cDNA for FAM182B Gene

(4) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM182B Gene

Family with sequence similarity 182, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM182B Gene

No ASD Table

Relevant External Links for FAM182B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM182B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM182B Gene

mRNA differential expression in normal tissues according to GTEx for FAM182B Gene

This gene is overexpressed in Testis (x6.5).

NURSA nuclear receptor signaling pathways regulating expression of FAM182B Gene:


SOURCE GeneReport for Unigene cluster for FAM182B Gene:


Evidence on tissue expression from TISSUES for FAM182B Gene

  • Lung(4.8)
  • Nervous system(3.8)
  • Liver(3.5)
  • Eye(2)
genes like me logo Genes that share expression patterns with FAM182B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM182B Gene

Orthologs for FAM182B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM182B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 86 (a)
-- 34
  • 84 (a)
Species where no ortholog for FAM182B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM182B Gene

Gene Tree for FAM182B (if available)
Gene Tree for FAM182B (if available)

Paralogs for FAM182B Gene

(1) SIMAP similar genes for FAM182B Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM182B: view

No data available for Paralogs for FAM182B Gene

Variants for FAM182B Gene

Sequence variations from dbSNP and Humsavar for FAM182B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000520333 -- 25,773,931(+) TTCAT(C/T)TCTGG intron-variant, nc-transcript-variant
rs1001197638 -- 25,774,299(+) TAAAA(C/T)CTTTC intron-variant
rs1001801140 -- 25,776,312(+) AAAGC(C/G)TAATT intron-variant
rs1003212155 -- 25,778,732(+) GTTCT(C/T)ATAAC intron-variant
rs1003694035 -- 25,764,464(+) GTGGG(A/G)CTGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM182B Gene

Variant ID Type Subtype PubMed ID
nsv979422 CNV duplication 23825009
nsv9794 CNV loss 18304495
nsv953010 CNV duplication 24416366
nsv820681 CNV duplication 20802225
nsv7340 OTHER inversion 18451855
nsv585749 CNV loss 21841781
nsv522873 CNV gain 19592680
nsv510784 CNV deletion 20534489
nsv470545 CNV gain 18288195
nsv1153810 OTHER inversion 26484159
nsv1152348 CNV duplication 26484159
nsv1147282 CNV duplication 26484159
nsv1145771 CNV duplication 26484159
nsv1141963 OTHER inversion 24896259
nsv1138935 CNV deletion 24896259
nsv1115600 CNV duplication 24896259
nsv1115599 CNV duplication 24896259
nsv1110366 CNV duplication 24896259
nsv1110365 CNV duplication 24896259
nsv1078481 CNV duplication 25765185
nsv1078480 CNV duplication 25765185
nsv1078479 CNV duplication 25765185
nsv1062442 CNV gain 25217958
esv990797 CNV gain 20482838
esv3575367 CNV gain 25503493
esv3449831 CNV duplication 20981092
esv3429256 CNV duplication 20981092
esv3388004 CNV duplication 20981092
esv3364413 CNV duplication 20981092
esv3352879 CNV duplication 20981092
esv3352094 CNV duplication 20981092
esv2758790 CNV gain+loss 17122850
esv23664 CNV gain+loss 19812545
dgv7521n54 CNV loss 21841781
dgv4291n100 CNV gain 25217958
dgv2416e59 CNV duplication 20981092
dgv2415e59 CNV duplication 20981092
dgv2231n106 CNV duplication 24896259

Variation tolerance for FAM182B Gene

Gene Damage Index Score: 0.85; 17.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM182B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM182B Gene

Disorders for FAM182B Gene

Relevant External Links for FAM182B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM182B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM182B Gene

Publications for FAM182B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 60
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for FAM182B Gene

Sources for FAM182B Gene

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