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Aliases for FAM181B Gene

Aliases for FAM181B Gene

  • Family With Sequence Similarity 181, Member B 2 3

External Ids for FAM181B Gene

Previous GeneCards Identifiers for FAM181B Gene

  • GC11M082122
  • GC11M082443
  • GC11M078740

Summaries for FAM181B Gene

GeneCards Summary for FAM181B Gene

FAM181B (Family With Sequence Similarity 181, Member B) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM181B Gene

Genomics for FAM181B Gene

Regulatory Elements for FAM181B Gene

Genomic Location for FAM181B Gene

Start:
82,729,941 bp from pter
End:
82,733,864 bp from pter
Size:
3,924 bases
Orientation:
Minus strand

Genomic View for FAM181B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM181B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM181B Gene

Proteins for FAM181B Gene

  • Protein details for FAM181B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NEQ2-F181B_HUMAN
    Recommended name:
    Protein FAM181B
    Protein Accession:
    A6NEQ2
    Secondary Accessions:
    • B2RWP1

    Protein attributes for FAM181B Gene

    Size:
    426 amino acids
    Molecular mass:
    42657 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM181B Gene

Proteomics data for FAM181B Gene at MOPED

Post-translational modifications for FAM181B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM181B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM181B Gene

Domains for FAM181B Gene

Protein Domains for FAM181B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM181B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NEQ2

UniProtKB/Swiss-Prot:

F181B_HUMAN :
  • A6NEQ2
Family:
  • Belongs to the FAM181 family.
genes like me logo Genes that share domains with FAM181B: view

No data available for Gene Families for FAM181B Gene

Function for FAM181B Gene

Phenotypes for FAM181B Gene

genes like me logo Genes that share phenotypes with FAM181B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM181B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM181B Gene

Localization for FAM181B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM181B Gene COMPARTMENTS Subcellular localization image for FAM181B gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM181B Gene

Pathways for FAM181B Gene

SuperPathways for FAM181B Gene

No Data Available

Interacting Proteins for FAM181B Gene

Gene Ontology (GO) - Biological Process for FAM181B Gene

None

No data available for Pathways by source for FAM181B Gene

Transcripts for FAM181B Gene

mRNA/cDNA for FAM181B Gene

(32) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM181B Gene

Family with sequence similarity 181, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM181B

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM181B
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM181B Gene

No ASD Table

Relevant External Links for FAM181B Gene

GeneLoc Exon Structure for
FAM181B
ECgene alternative splicing isoforms for
FAM181B

Expression for FAM181B Gene

mRNA expression in normal human tissues for FAM181B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM181B Gene

This gene is overexpressed in Brain - Amygdala (4.7), Brain - Substantia nigra (4.3), Brain - Spinal cord (cervical c-1) (4.1), and Brain - Hippocampus (4.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM181B Gene

SOURCE GeneReport for Unigene cluster for FAM181B Gene Hs.448218

genes like me logo Genes that share expressions with FAM181B: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM181B Gene

Orthologs for FAM181B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM181B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM181B 36
  • 99 (a)
OneToOne
LOC748983 35
  • 99.3 (n)
  • 99.06 (a)
cow
(Bos Taurus)
Mammalia FAM181B 35
  • 87.43 (n)
  • 84.96 (a)
FAM181B 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM181B 35
  • 83.76 (n)
  • 81.41 (a)
FAM181B 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam181b 35
  • 80 (n)
  • 78.55 (a)
Fam181b 16
oppossum
(Monodelphis domestica)
Mammalia FAM181B 36
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam181b 35
  • 78.87 (n)
  • 76.56 (a)
chicken
(Gallus gallus)
Aves FAM181B 35
  • 70.56 (n)
  • 67.5 (a)
FAM181B 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM181B 36
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam181b 35
  • 54.01 (n)
  • 47.15 (a)
zebrafish
(Danio rerio)
Actinopterygii CR538726.1 36
  • 46 (a)
OneToOne
LOC101883805 35
  • 52.8 (n)
  • 47.94 (a)
Species with no ortholog for FAM181B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM181B Gene

ENSEMBL:
Gene Tree for FAM181B (if available)
TreeFam:
Gene Tree for FAM181B (if available)

Paralogs for FAM181B Gene

No data available for Paralogs for FAM181B Gene

Variants for FAM181B Gene

Sequence variations from dbSNP and Humsavar for FAM181B Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs3780 -- 82,732,375(+) TTCTT(C/T)AGATT utr-variant-3-prime
rs986096 -- 82,733,184(-) CCGGC(G/T)GGGGG reference, synonymous-codon
rs986097 - 82,733,174(-) GTGAG(C/G)TGGCT missense, reference
rs2291793 -- 82,732,775(-) ACCTA(C/T)TGTAC reference, synonymous-codon
rs6592081 - 82,732,630(+) GGCCC(C/G)GCCCG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for FAM181B Gene

Variant ID Type Subtype PubMed ID
esv33531 CNV Loss 17666407
nsv413 CNV Insertion 18451855

Relevant External Links for FAM181B Gene

HapMap Linkage Disequilibrium report
FAM181B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM181B Gene

Disorders for FAM181B Gene

No disorders were found for FAM181B Gene.

No data available for UniProtKB/Swiss-Prot for FAM181B Gene

Publications for FAM181B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for FAM181B Gene

Sources for FAM181B Gene

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