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Aliases for FAM180A Gene

Aliases for FAM180A Gene

  • Family With Sequence Similarity 180, Member A 2 3
  • Protein FAM180A 3
  • HWKM1940 3
  • UNQ1940 3

External Ids for FAM180A Gene

Previous GeneCards Identifiers for FAM180A Gene

  • GC07M135065
  • GC07M135413
  • GC07M129717

Summaries for FAM180A Gene

GeneCards Summary for FAM180A Gene

FAM180A (Family With Sequence Similarity 180, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM180A Gene

Genomics for FAM180A Gene

Regulatory Elements for FAM180A Gene

Genomic Location for FAM180A Gene

135,728,348 bp from pter
135,748,868 bp from pter
20,521 bases
Minus strand

Genomic View for FAM180A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM180A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM180A Gene

Proteins for FAM180A Gene

  • Protein details for FAM180A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM180A
    Protein Accession:
    Secondary Accessions:
    • B2RP85

    Protein attributes for FAM180A Gene

    173 amino acids
    Molecular mass:
    19733 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM180A Gene

Proteomics data for FAM180A Gene at MOPED

Post-translational modifications for FAM180A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM180A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM180A Gene

Domains for FAM180A Gene

Protein Domains for FAM180A Gene


Suggested Antigen Peptide Sequences for FAM180A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM180 family.
  • Belongs to the FAM180 family.
genes like me logo Genes that share domains with FAM180A: view

No data available for Gene Families for FAM180A Gene

Function for FAM180A Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM180A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM180A Gene

Localization for FAM180A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM180A Gene


Subcellular locations from

Jensen Localization Image for FAM180A Gene COMPARTMENTS Subcellular localization image for FAM180A gene
Compartment Confidence
extracellular 3
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for FAM180A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM180A: view

Pathways for FAM180A Gene

SuperPathways for FAM180A Gene

No Data Available

Interacting Proteins for FAM180A Gene

Gene Ontology (GO) - Biological Process for FAM180A Gene


No data available for Pathways by source for FAM180A Gene

Transcripts for FAM180A Gene

mRNA/cDNA for FAM180A Gene

Unigene Clusters for FAM180A Gene

Family with sequence similarity 180, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM180A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM180A Gene

No ASD Table

Relevant External Links for FAM180A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM180A Gene

mRNA expression in normal human tissues for FAM180A Gene

mRNA differential expression in normal tissues according to GTEx for FAM180A Gene

This gene is overexpressed in Artery - Aorta (12.9).

Protein differential expression in normal tissues for FAM180A Gene

This gene is overexpressed in Serum (22.7), Bone (15.2), Esophagus (13.0), Bone marrow mesenchymal stem cell (9.9), and Lung (8.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM180A Gene

SOURCE GeneReport for Unigene cluster for FAM180A Gene Hs.55200

genes like me logo Genes that share expressions with FAM180A: view

Expression partners for FAM180A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM180A Gene

Orthologs for FAM180A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM180A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM180A 35
  • 86.32 (n)
  • 83.82 (a)
FAM180A 36
  • 84 (a)
(Canis familiaris)
Mammalia FAM180A 35
  • 87.67 (n)
  • 83.24 (a)
FAM180A 36
  • 83 (a)
(Mus musculus)
Mammalia Fam180a 35
  • 79.73 (n)
  • 79.53 (a)
Fam180a 16
Fam180a 36
  • 79 (a)
(Pan troglodytes)
Mammalia FAM180A 35
  • 99.61 (n)
  • 99.42 (a)
FAM180A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam180a 35
  • 81.09 (n)
  • 81.29 (a)
(Monodelphis domestica)
Mammalia FAM180A 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia FAM180A 36
  • 75 (a)
(Gallus gallus)
Aves FAM180A 35
  • 72.97 (n)
  • 70.12 (a)
FAM180A 36
  • 67 (a)
(Anolis carolinensis)
Reptilia FAM180A 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam180a 35
  • 63.83 (n)
  • 56.21 (a)
(Danio rerio)
Actinopterygii LOC100538098 35
  • 51.3 (n)
  • 41.84 (a)
CABZ01068473.1 36
  • 35 (a)
Species with no ortholog for FAM180A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM180A Gene

Gene Tree for FAM180A (if available)
Gene Tree for FAM180A (if available)

Paralogs for FAM180A Gene

No data available for Paralogs for FAM180A Gene

Variants for FAM180A Gene

Sequence variations from dbSNP and Humsavar for FAM180A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs3110819 -- 135,731,770(+) CTTCC(A/T)GTGTC intron-variant, utr-variant-3-prime
rs3110820 -- 135,733,878(+) GTAAG(A/T)GTTTT utr-variant-3-prime, intron-variant
rs3112371 -- 135,730,280(+) CTCAC(A/G)CCTGT utr-variant-3-prime, intron-variant
rs3112372 -- 135,732,036(+) CCAGA(C/T)GCTCG intron-variant, utr-variant-3-prime
rs3112373 -- 135,732,565(+) gtgcg(C/T)gccta intron-variant, utr-variant-3-prime

Relevant External Links for FAM180A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM180A Gene

Disorders for FAM180A Gene

No disorders were found for FAM180A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM180A Gene

Publications for FAM180A Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 2 3 4
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  4. Genome-wide association study of chronic periodontitis in a general German population. (PMID: 24024966) Teumer A. … Kocher T. (J. Clin. Periodontol. 2013) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for FAM180A Gene

Sources for FAM180A Gene

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