Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM180A Gene

Aliases for FAM180A Gene

  • Family With Sequence Similarity 180 Member A 2 3 5
  • Family With Sequence Similarity 180, Member A 2 3
  • HWKM1940 3
  • UNQ1940 3

External Ids for FAM180A Gene

Previous GeneCards Identifiers for FAM180A Gene

  • GC07M135065
  • GC07M135413
  • GC07M129717

Summaries for FAM180A Gene

GeneCards Summary for FAM180A Gene

FAM180A (Family With Sequence Similarity 180 Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM180A Gene

Genomics for FAM180A Gene

Regulatory Elements for FAM180A Gene

Enhancers for FAM180A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM180A on UCSC Golden Path with GeneCards custom track

Promoters for FAM180A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM180A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM180A Gene

Chromosome:
7
Start:
135,728,348 bp from pter
End:
135,748,867 bp from pter
Size:
20,520 bases
Orientation:
Minus strand

Genomic View for FAM180A Gene

Genes around FAM180A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM180A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM180A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM180A Gene

Proteins for FAM180A Gene

  • Protein details for FAM180A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UWF9-F180A_HUMAN
    Recommended name:
    Protein FAM180A
    Protein Accession:
    Q6UWF9
    Secondary Accessions:
    • B2RP85

    Protein attributes for FAM180A Gene

    Size:
    173 amino acids
    Molecular mass:
    19733 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM180A Gene

Proteomics data for FAM180A Gene at MOPED

Post-translational modifications for FAM180A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM180A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM180A Gene

Domains & Families for FAM180A Gene

Protein Domains for FAM180A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM180A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UWF9

UniProtKB/Swiss-Prot:

F180A_HUMAN :
  • Belongs to the FAM180 family.
Family:
  • Belongs to the FAM180 family.
genes like me logo Genes that share domains with FAM180A: view

No data available for Gene Families for FAM180A Gene

Function for FAM180A Gene

Phenotypes for FAM180A Gene

genes like me logo Genes that share phenotypes with FAM180A: view

Animal Model Products

  • Taconic Biosciences Mouse Models for FAM180A

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM180A Gene

Localization for FAM180A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM180A Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM180A Gene COMPARTMENTS Subcellular localization image for FAM180A gene
Compartment Confidence
extracellular 4
cytosol 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for FAM180A Gene

Pathways & Interactions for FAM180A Gene

SuperPathways for FAM180A Gene

No Data Available

Interacting Proteins for FAM180A Gene

Gene Ontology (GO) - Biological Process for FAM180A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM180A Gene

Drugs & Compounds for FAM180A Gene

No Compound Related Data Available

Transcripts for FAM180A Gene

mRNA/cDNA for FAM180A Gene

Unigene Clusters for FAM180A Gene

Family with sequence similarity 180, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM180A Gene

No ASD Table

Relevant External Links for FAM180A Gene

GeneLoc Exon Structure for
FAM180A
ECgene alternative splicing isoforms for
FAM180A

Expression for FAM180A Gene

mRNA expression in normal human tissues for FAM180A Gene

mRNA differential expression in normal tissues according to GTEx for FAM180A Gene

This gene is overexpressed in Artery - Aorta (x12.9).

Protein differential expression in normal tissues from HIPED for FAM180A Gene

This gene is overexpressed in Serum (22.7), Bone (15.2), Esophagus (13.0), Bone marrow mesenchymal stem cell (9.9), and Lung (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM180A Gene



SOURCE GeneReport for Unigene cluster for FAM180A Gene Hs.55200

genes like me logo Genes that share expression patterns with FAM180A: view

Protein tissue co-expression partners for FAM180A Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for FAM180A Gene

Orthologs for FAM180A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM180A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM180A 35
  • 86.32 (n)
  • 83.82 (a)
FAM180A 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM180A 35
  • 87.67 (n)
  • 83.24 (a)
FAM180A 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam180a 35
  • 79.73 (n)
  • 79.53 (a)
Fam180a 16
Fam180a 36
  • 79 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM180A 35
  • 99.61 (n)
  • 99.42 (a)
FAM180A 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam180a 35
  • 81.09 (n)
  • 81.29 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM180A 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM180A 36
  • 75 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM180A 35
  • 72.97 (n)
  • 70.12 (a)
FAM180A 36
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM180A 36
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam180a 35
  • 63.83 (n)
  • 56.21 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100538098 35
  • 51.3 (n)
  • 41.84 (a)
CABZ01068473.1 36
  • 35 (a)
OneToOne
Species with no ortholog for FAM180A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM180A Gene

ENSEMBL:
Gene Tree for FAM180A (if available)
TreeFam:
Gene Tree for FAM180A (if available)

Paralogs for FAM180A Gene

No data available for Paralogs for FAM180A Gene

Variants for FAM180A Gene

Sequence variations from dbSNP and Humsavar for FAM180A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs3112374 - 135,734,211(+) GATGA(A/C/T)GTTGT reference, missense
rs6958210 -- 135,735,199(+) ACCCC(A/G)AGCCA intron-variant
rs6963905 -- 135,736,688(+) GCCAG(A/G)CAGCA intron-variant
rs6963912 -- 135,736,663(+) GAAAC(A/C)CAGCT intron-variant
rs13221513 -- 135,745,361(+) GCATA(A/T)TTCAT intron-variant

Variation tolerance for FAM180A Gene

Residual Variation Intolerance Score: 83.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.17; 51.78% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FAM180A Gene

Disorders for FAM180A Gene

Relevant External Links for FAM180A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM180A

No disorders were found for FAM180A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM180A Gene

Publications for FAM180A Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 2 3 4 67
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3
  3. Genome-wide association study of chronic periodontitis in a general German population. (PMID: 24024966) Teumer A. … Kocher T. (J. Clin. Periodontol. 2013) 3
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM180A Gene

Sources for FAM180A Gene

Content