FAM179A Gene
protein-coding GIFtS: 40
GCID: GC02P029179
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|
family with sequence similarity 179, member A
| |
Aliases
for FAM179A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 179, Member A1 2 | | FLJ432491 | | LOC1651861 | | Protein FAM179A2 |
Export aliases for FAM179A gene to outside databasesPrevious GC identifer: GC02P029032 |
Summaries
for FAM179A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM179A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM179A gene promoter:
GR Pbx1a p53 GR-beta AREB6 FOXO1a GR-alpha Pax-4a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM179A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM179A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p23.2 Ensembl cytogenetic band: 2p23.2 HGNC cytogenetic band: 2p23.2FAM179A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P029179: view genomic region
(about GC identifiers)
Start:
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29,179,477 bp from pter |
End:
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29,275,096 bp from pter |
Size:
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95,620 bases |
Orientation:
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plus strand |
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Proteins
for FAM179A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F179A_HUMAN, Q6ZUX3 (See
protein sequence)Recommended Name: Protein FAM179A Size: 1019 amino acids; 111153 Da
Secondary accessions: Q6ZUF5Alternative splicing: 3 isoforms: Q6ZUX3-1 Q6ZUX3-2 Q6ZUX3-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM179A: NX_Q6ZUX3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZUX3
FAM179A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_954974.2
ENSEMBL proteins: ENSP00000384897 ENSP00000402415 ENSP00000368876 ENSP00000396739 ENSP00000384699
Human Recombinant Protein Products:
FAM179A Antibody Products:
Assay Products for FAM179A: |
Protein
Domains /
Families
for FAM179A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM179A for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6ZUX3ProtoNet protein and cluster: Q6ZUX3 1 Blocks protein family: IPB000357 HEAT repeat
UniProtKB/Swiss-Prot: F179A_HUMAN, Q6ZUX3Similarity: Belongs to the FAM179 family |
Function
for FAM179A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM179A (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM179A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM179A (NM_199280) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM179A | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM179A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM179A |
1 GenomeRNAi human phenotype for FAM179A:
|
Pathways & Interactions
for FAM179A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM179A
|
Drugs & Compounds
for FAM179A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM179A
Search CenterWatch for drugs/clinical trials and news about FAM179A / F179A
|
Transcripts
for FAM179A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM179A gene: NM_199280.2 Unigene Cluster for FAM179A: Family with sequence similarity 179, member A Hs.525977 [show with all ESTs]Unigene Representative Sequence: NM_1992808 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000401723 ENST00000420297 ENST00000379558(uc010ezl.3 uc010ymm.2 uc002rmr.4)
ENST00000465300 ENST00000440012 ENST00000460951 ENST00000475900(uc002rms.1)
ENST00000403861
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM179A (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM179A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM179A (NM_199280) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM179A | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM179A |
Additional cDNA sequence: AK125239.1 AK296977.1 5 DOTS entries: DT.100016081 DT.101976405 DT.121035204 DT.91963696 DT.95086536 18 AceView cDNA sequences: BQ772038 BU101516 AK125744 AI632621 BU687028 AI799168 NM_199280 BG656432 AW002821 AK125239 BI828991 AI657079 AI860547 BM686358 BG656126 BE159786 N53431 BE159784
GeneLoc Exon Structure
|
Expression
for FAM179A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM179A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTATATTTTG
About this image
See FAM179A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM179A
SOURCE GeneReport for Unigene cluster: Hs.525977
SABiosciences Custom PCR Arrays for FAM179A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM179A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM179A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM179A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM179A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM179A |
Orthologs
for FAM179A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FAM179A gene from 4/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM179A6 |
Uncharacterized protein |
59(a) |
1 ↔ 1 |
3(8466063-8483222) |
lizard
(Anolis carolinensis) |
Reptilia |
FAM179A6 |
-- |
57(a) |
1 ↔ 1 |
1(248474139-248491764) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG423996 |
-- |
6(a) |
1 → many |
2L(144231-153288) |
worm
(Caenorhabditis elegans) |
Secernentea |
che-126 |
abnormal CHEmotaxis family member (che-12) |
12(a) |
possible ortholog |
V(10299448-10307329) |
ENSEMBL Gene Tree for FAM179A (if available)
TreeFam Gene Tree for FAM179A (if available) |
Paralogs
for FAM179A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM179A gene
- FAM179B2
1 SIMAP similar gene for FAM179A using alignment to 5 protein entries: F179A_HUMAN (see all proteins):FAM179B
FAM179A for paralogs About GeneDecksing
|
Genomic Variants
for FAM179A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM179A (29179477 - 29275096 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for FAM179A
4 CNVs: 61755 2374 43237 8366 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM179A |
|
Disorders
/ Diseases
for FAM179A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM179A for disorders About GeneDecksing
2  diseases for FAM179A: About MalaCardsmajor depressive disorder neuronitis
Export disorders for FAM179A gene to outside databases
|
Publications
for FAM179A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM179A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM179A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1, 3 Kimura K.... Sugano S. (2006)
- Genome-wide association study of recurrent early-onse t major depressive disorder. (PubMed id 20125088)1 Shi J....Levinson D.F. (2010)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for FAM179A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM179A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM179A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM179A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM179A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM179A gene:
Search GeneIP for patents involving FAM179A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM179A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM179A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM179A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM179A | | | OriGene Protein Over-expression Lysate for FAM179A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM179A | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM179A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM179A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM179A | | OriGene Custom Protein Services for FAM179A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM179A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM179A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM179A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM179A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM179A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM179A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM179A |
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 | | | FAM179A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM179A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM179A |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM179A |
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