FAM178B Gene

Aliases
for FAM178B gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Previous GC identifers: GC02M096906 GC02M091501

Summaries
for FAM178B gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Genomic Views
for FAM178B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence at NCBI GenBank:

NC_000002.11  NT_005403.18  NC_018913.2  

SwitchGear Promoter luciferase reporter plasmid: FAM178B promoter sequence

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM178B

FAM178B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M097541:  view genomic region     (about GC identifiers)

Proteins
for FAM178B gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

Explore the universe of human proteins at neXtProt for FAM178B: NX_Q8IXR5

Explore proteomics data for FAM178B at MOPED


See FAM178B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

FAM178B Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for FAM178B OriGene Custom MassSpec OriGene Custom Protein Services for FAM178B
	GenScript Custom Purified and Recombinant Proteins Services for FAM178B
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for FAM178B
	Search eBioscience for Proteins for FAM178B
	Search GeneTex for Proteins for FAM178B
	Search antibodies-online for proteins for FAM178B
	Search antibodies-online for peptides for FAM178B

FAM178B Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for FAM178B
	Novus Biologicals FAM178B Antibodies
	Search for Antibodies for FAM178B at Abcam
	Cloud-Clone Corp. Antibodies for FAM178B
	Search ThermoFisher Antibodies for FAM178B
	antibodies-online antibodies for FAM178B (2 products)

FAM178B Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for FAM178B
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for FAM178B
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for FAM178B Cloud-Clone Corp. CLIAs for FAM178B
	Search eBioscience for ELISAs for FAM178B
	antibodies-online kits for FAM178B (4 products)

Domains /
Families
for FAM178B gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
About This Section

ProtoNet protein and cluster: Q8IXR5

Find genes that share domains with FAM178B           About GenesLikeMe

Function
for FAM178B gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Localization
for FAM178B gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Pathways & Interactions
for FAM178B gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Drugs & Compounds
for FAM178B gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
About This Section

Transcripts
for FAM178B gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

Expression
for FAM178B gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAM178B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CTGACCAGCC

About this image

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for FAM178B
		Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM178B
		QuantiTect SYBR Green Assays in human, mouse, rat FAM178B
		QuantiFast Probe-based Assays in human, mouse, rat FAM178B

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM178B

Orthologs
for FAM178B gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

Paralogs
for FAM178B gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
About This Section

Paralogs for FAM178B gene

FAM178A²  

Find genes that share paralogs with FAM178B           About GenesLikeMe


2 Pseudogenes.org Pseudogenes for FAM178B
PGOHUM00000240205 PGOHUM00000240797

Genomic Variants
for FAM178B gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

Selected SNPs for FAM178B (see all 2168)    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs788745981,2	C,F	--	97541180(+)	ATGAAC/TTCATC	3	--	int1		2		WA NA	238
rs75817641,2	C,F,A,H	--	97541238(+)	TGAACC/TGCCCC	3	--	int1		25		NS EA NA WA CSA	2348
rs1916561161,2		--	97541239(+)	GAACTA/GCCCCC	3	--	int1		0	--	--	--	--
rs1390179371,2		--	97541297(+)	TTAAGA/TGTAAT	3	--	int1		0	--	--	--	--
rs1406958791,2		--	97541333(+)	TGTGCA/GTCCTC	3	--	int1		0	--	--	--	--
rs1841992321,2		--	97541335(+)	TGCGTC/TCTCCT	3	--	int1		0	--	--	--	--
rs2018356821,2		--	97541452(+)	CCCCT-/CCCCGG	3	--	int1		0	--	--	--	--
rs1880951561,2		--	97541580(+)	CATGAA/GCCCTC	3	--	int1		0	--	--	--	--
rs1810512961,2	C	--	97541601(+)	CTGAAA/GGAAGT	3	--	int1		0	--	--	--	--
rs1412202641,2		--	97541602(+)	TGAAGG/TAAGTG	3	--	int1		0	--	--	--	--

HapMap Linkage Disequilibrium report for FAM178B (97541619 - 97684175 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10 variations for FAM178B:    About this table    

Variant ID	Type	Subtype	PubMed ID
dgv650e201	CNV	Deletion	23290073
nsv512773	CNV	Insertion	21212237
dgv4249n71	CNV	Loss	21882294
nsv874680	CNV	Loss	21882294
nsv526313	CNV	Loss	19592680
nsv874677	CNV	Loss	21882294
esv32727	CNV	Gain+Loss	17666407
esv718	CNV	CNV	17122850
essv10696	CNV	CNV	17122850
esv5003	CNV	Complex	18987735

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing FAM178B

DNA2.0 Custom Variant and Variant Library Synthesis for FAM178B

Disorders / Diseases
for FAM178B gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
About This Section

Publications
for FAM178B gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2, 3} Zhang Q.-H.... Chen Z. (Genome Res. 2000)
2. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)¹ Zhou H....Espeseth A.S. (amp 2008)
3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (Genome Res. 2006)
4. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (Cell 2005)
5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)² Hillier L.W.... Wilson R.K. (Nature 2005)
6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S.... Malek J. (Genome Res. 2004)
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

External Searches for FAM178B gene

Genome Databases showing FAM178B gene

Other Databases showing FAM178B gene

Specialized Databases showing FAM178B gene

Products
for FAM178B gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
About This Section