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FAM178A Gene

protein-coding   GIFtS: 50
GCID: GC10P102663

Family With Sequence Similarity 178, Member A

(Previous name: chromosome 10 open reading frame 6)
(Previous symbol: C10orf6)
  See FAM178A-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 178, Member A1 2
C10orf61 2 3 5
Chromosome 10 Open Reading Frame 61
Protein FAM178A2

External Ids:    HGNC: 178141   Entrez Gene: 557192   Ensembl: ENSG000001199067   OMIM: 6103485   UniProtKB: Q8IX213   

Export aliases for FAM178A gene to outside databases

Previous GC identifer: GC10P096300


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM178A Gene:
FAM178A (family with sequence similarity 178, member A) is a protein-coding gene. Diseases associated with FAM178A include infantile onset spinocerebellar ataxia. An important paralog of this gene is FAM178B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM178A gene promoter:
         Sp1   FOXO3   Nkx5-1   FOXO3b   Egr-2   CREB   deltaCREB   FOXO3a   ZIC2/Zic2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAM178A promoter sequence
   Search Chromatin IP Primers for FAM178A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM178A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.31   Ensembl cytogenetic band:  10q24.31   HGNC cytogenetic band: 10q24.31

FAM178A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM178A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P102663:  view genomic region     (about GC identifiers)

Start:
102,672,326 bp from pter      End:
102,724,893 bp from pter
Size:
52,568 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: F178A_HUMAN, Q8IX21 (See protein sequence)
Recommended Name: Protein FAM178A  
Size: 1173 amino acids; 131873 Da
Miscellaneous: Localized in the locus associated with inherited infantile onset spinocerebellar ataxia (IOSCA). No
mutation were found associated with IOSCA compared to control subjects. The expression level in the brain was not
different between the 2 populations
Sequence caution: Sequence=BAA91657.1; Type=Erroneous initiation;
Secondary accessions: A8K950 B1AL17 Q5W0L8 Q9NPE8
Alternative splicing: 2 isoforms:  Q8IX21-1   Q8IX21-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM178A: NX_Q8IX21

Explore proteomics data for FAM178A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM178A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001129595.1  NP_001230699.1  NP_060591.3  

    ENSEMBL proteins: 
     ENSP00000238961   ENSP00000359294   ENSP00000359292   ENSP00000476379  

    FAM178A Human Recombinant Protein Products:

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    OriGene Custom Protein Services for FAM178A
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM178A

     
    Search eBioscience for Proteins for FAM178A 

     
    Search antibodies-online for proteins for FAM178A 

     
    Search antibodies-online for peptides for FAM178A

    FAM178A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for FAM178A
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    antibodies-online antibodies for FAM178A 

    FAM178A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for FAM178A
    Cloud-Clone Corp. CLIAs for FAM178A
    Search eBioscience for ELISAs for FAM178A 
    antibodies-online kits for FAM178A (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026161 FAM178

    Graphical View of Domain Structure for InterPro Entry Q8IX21

    ProtoNet protein and cluster: Q8IX21

    UniProtKB/Swiss-Prot: F178A_HUMAN, Q8IX21
    Similarity: Belongs to the FAM178 family


    Find genes that share domains with FAM178A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FAM178A

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM178A:
    hsa-mir-215-5p (MIRT024507), hsa-mir-192-5p (MIRT026889), hsa-let-7b-5p (MIRT051982)

    Block miRNA regulation of human, mouse, rat FAM178A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM178A (see all 105):
    hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-4254 hsa-miR-631 hsa-miR-371-5p hsa-miR-519a hsa-miR-629* hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidFAM178A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM178A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM178A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FAM178A

    Clone
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    OriGene clones in human, mouse for FAM178A (see all 12)
    OriGene ORF clones in mouse, rat for FAM178A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): FAM178A (NM_018121)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM178A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM178A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAM178A
    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM178A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM178A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    golgi apparatus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--

    Find genes that share ontologies with FAM178A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM178A
    Interactions:

        Search GeneGlobe Interaction Network for FAM178A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    Selected Interacting proteins for FAM178A (Q8IX212, 3 ENSP000003592924) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    OPTNQ96CV93I2D: score=1 
    SCHIP1Q9P0W53I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM178A (F178A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM178A gene (4 alternative transcripts): 
    NM_144592.1  NM_001136123.1  NM_001243770.1  NM_018121.3  

    Unigene Cluster for FAM178A:

    Family with sequence similarity 178, member A
    Hs.447458  [show with all ESTs]
    Unigene Representative Sequence: NM_018121
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000238961(uc001krt.4) ENST00000370271(uc001krr.1 uc001kru.1)
    ENST00000370269(uc001krs.3) ENST00000609386 ENST00000481654
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM178A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM178A (see all 105):
    hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-4254 hsa-miR-631 hsa-miR-371-5p hsa-miR-519a hsa-miR-629* hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidFAM178A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM178A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM178A
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM178A (see all 12)
    OriGene ORF clones in mouse, rat for FAM178A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): FAM178A (NM_018121)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM178A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM178A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM178A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM178A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM178A
      QuantiFast Probe-based Assays in human, mouse, rat FAM178A

    Additional mRNA sequence: 

    AF460991.1 AF460992.1 AK001374.1 AK024283.1 AK292565.1 AL832343.1 AL832383.1 AL833126.1 
    BC015131.1 BC020915.1 BC030565.1 BC047715.1 BC064526.1 BC073832.1 

    13 DOTS entries:

    DT.447779  DT.100024753  DT.403630  DT.428704  DT.121266513  DT.121266531  DT.91816894  DT.92067167 
    DT.100669050  DT.121266456  DT.121266517  DT.100644001  DT.95176762 

    Selected AceView cDNA sequences (see all 203):

    AA570100 NM_018121 BC047715 AI523516 AA379912 AA757128 CK826320 BC015131 
    AU127141 AF460992 CD722156 BQ050508 BF438800 CB045246 W87812 BM463515 
    BM699473 BM478882 AA721345 W87420 AK001374 CA406897 AA343965 AA279837 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM178A (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^
    SP1:                                                                                      -     -     -                                               -         
    SP2:                                                                                      -     -     -                                               -         
    SP3:                                                                                                  -                                                         
    SP4:                    -     -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 21a · 21b · 21c ^ 22a · 22b · 22c
    SP1:  -           -                     
    SP2:  -                                 
    SP3:                                    
    SP4:                                    
    SP5:  -           -                     


    ECgene alternative splicing isoforms for FAM178A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM178A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAGTGTCG
    FAM178A Expression
    About this image


    FAM178A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Gonad
             XY Germ Cells Testis Cord
    FAM178A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM178A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.447458

    UniProtKB/Swiss-Prot: F178A_HUMAN, Q8IX21
    Tissue specificity: Widely expressed. Expressed at higher level in skeletal muscle and at slightly lower level in
    brain, liver and heart, than in lung, kidney, spleen and thymus

        Custom PCR Arrays for FAM178A
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat FAM178A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM178A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FAM178A gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam178a1 , 5 family with sequence similarity 178, member A1, 5 88(n)1
    85.7(a)1
      19 (38.16 cM)5
    2261511  NM_001081225.11  NP_001074694.11 
     449311195 
    chicken
    (Gallus gallus)
    Aves C10ORF61 family with sequence similarity 178, member A 66.11(n)
    57.34(a)
      423858  XM_421726.4  XP_421726.4 
    lizard
    (Anolis carolinensis)
    Reptilia FAM178A6
    family with sequence similarity 178, member A
    31(a)
    1 ↔ 1
    3(39515962-39561966)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.322972 Xenopus laevis transcribed sequences 77.23(n)    BJ098634.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam178a6
    family with sequence similarity 178, member A
    22(a)
    1 ↔ 1
    13(8982107-9021722) ENSDARG00000003328


    ENSEMBL Gene Tree for FAM178A (if available)
    TreeFam Gene Tree for FAM178A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM178A gene
    FAM178B2  

    Find genes that share paralogs with FAM178A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM178A (see all 969)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1468921791,2
    C--102670347(+) CTACAA/TATTGA 3 -- us2k10--------
    rs1168336961,2
    F--102670440(+) GATATA/GAACAC 3 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1880742751,2
    --102670644(+) AAGAAA/GATATT 3 -- us2k10--------
    rs1908164131,2
    --102670822(+) GTACTA/GTAATC 3 -- us2k10--------
    rs1407178661,2
    --102670825(+) CTATAA/TTCCAA 3 -- us2k10--------
    rs1821346561,2
    --102670908(+) TGAATA/CGGATT 3 -- us2k10--------
    rs1879704921,2
    --102670942(+) TTATAC/GTACAG 3 -- us2k10--------
    rs780890081,2
    C,F--102671093(+) TTCTCC/TGCTAT 3 -- us2k11Minor allele frequency- T:0.03NA 120
    rs768419591,2
    C,F--102671118(+) TACCCT/ACTATT 3 -- us2k11Minor allele frequency- A:0.01WA 118
    rs1925986211,2
    --102671191(+) GTGAAC/TGTGAA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for FAM178A (102672326 - 102724893 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for FAM178A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv467443CNV Loss19166990
    nsv831965CNV Loss17160897
    nsv515627CNV Gain+Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM178A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM178A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610348    OMIM disorders: --

    1 disease for FAM178A:    
    About MalaCards
    infantile onset spinocerebellar ataxia


    Find genes that share disorders with FAM178A           About GenesLikeMe

    Genetic Association Database (GAD): FAM178A
    Human Genome Epidemiology (HuGE) Navigator: FAM178A (1 document)

    Export disorders for FAM178A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM178A gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with FAM178A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia. (PubMed id 12459258)1, 2, 3, 9 Nikali K.... Peltonen L. (Gene 2002)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PubMed id 20195357)1 Miyamoto-Sato E....Yanagawa H. (PLoS ONE 2010)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    10. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (Cell 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55719 HGNC: 17814 AceView: C10orf6 Ensembl:ENSG00000119906 euGenes: HUgn55719
    ECgene: FAM178A H-InvDB: FAM178A

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FAM178A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM178A gene:
    Search GeneIP for patents involving FAM178A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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