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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAM178A Gene

protein-coding   GIFtS: 46
GCID: GC10P102663

Family With Sequence Similarity 178, Member A

(Previous name: chromosome 10 open reading frame 6)
(Previous symbol: C10orf6)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Family With Sequence Similarity 178, Member A1 2
C10orf61 2 3 5
Chromosome 10 Open Reading Frame 61
Protein FAM178A2

External Ids:    HGNC: 178141   Entrez Gene: 557192   Ensembl: ENSG000001199067   OMIM: 6103485   UniProtKB: Q8IX213   

Export aliases for FAM178A gene to outside databases

Previous GC identifer: GC10P096300


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FAM178A Gene: 
FAM178A (family with sequence similarity 178, member A) is a protein-coding gene. Diseases associated with FAM178A include infantile onset spinocerebellar ataxia, and spinocerebellar ataxia. An important paralog of this gene is FAM178B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM178A gene promoter:
         Sp1   FOXO3   Nkx5-1   FOXO3b   Egr-2   CREB   deltaCREB   FOXO3a   ZIC2/Zic2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAM178A promoter sequence
   Search SABiosciences Chromatin IP Primers for FAM178A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM178A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.31   Ensembl cytogenetic band:  10q24.31   HGNC cytogenetic band: 10q24.31

FAM178A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM178A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P102663:  view genomic region     (about GC identifiers)

Start:
102,672,326 bp from pter      End:
102,724,893 bp from pter
Size:
52,568 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: F178A_HUMAN, Q8IX21 (See protein sequence)
Recommended Name: Protein FAM178A  
Size: 1173 amino acids; 131873 Da
Miscellaneous: Localized in the locus associated with inherited infantile onset spinocerebellar ataxia (IOSCA). No
mutation were found associated with IOSCA compared to control subjects. The expression level in the brain was not
different between the 2 populations
Sequence caution: Sequence=BAA91657.1; Type=Erroneous initiation;
Secondary accessions: A8K950 B1AL17 Q5W0L8 Q9NPE8
Alternative splicing: 2 isoforms:  Q8IX21-1   Q8IX21-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM178A: NX_Q8IX21

Explore proteomics data for FAM178A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IX21

  • FAM178A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FAM178A Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001129595.1  NP_001230699.1  NP_060591.3  

    ENSEMBL proteins: 
     ENSP00000359294   ENSP00000238961   ENSP00000359292  

    Human Recombinant Protein Products for FAM178A: 
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    OriGene Custom Protein Services for FAM178A
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM178A 


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    Novus Biologicals FAM178A Antibody
    Search for Antibodies for FAM178A at Abcam
    Cloud-Clone Corp. Antibodies for FAM178A 
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    Search LSBio for Antibodies for FAM178A 

    Assay Products for FAM178A: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for FAM178A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FAM178A 
    Cloud-Clone Corp. CLIAs for FAM178A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026161 FAM178

    Graphical View of Domain Structure for InterPro Entry Q8IX21

    ProtoNet protein and cluster: Q8IX21

    UniProtKB/Swiss-Prot: F178A_HUMAN, Q8IX21
    Similarity: Belongs to the FAM178 family


    FAM178A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FAM178A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAM178A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM178A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM178A 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM178A
    8/105 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM178A (see all 105):
    hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-4254 hsa-miR-631 hsa-miR-371-5p hsa-miR-519a hsa-miR-629* hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidFAM178A 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FAM178A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM178A

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for FAM178A
    Sirion Biotech Customized adenovirus for overexpression of FAM178A

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for FAM178A (see all 11)
    OriGene ORF clones in mouse, rat for FAM178A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): FAM178A (NM_018121)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM178A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM178A
    Sirion Biotech Customized lentivirus for stable overexpression of FAM178A 
                         Customized lentivirus expression plasmids for stable overexpression of FAM178A 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAM178A
    Search LifeMap BioReagents cell lines for FAM178A
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM178A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM178A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/7 Interacting proteins for FAM178A (Q8IX212, 3 ENSP000003592924) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    OPTNQ96CV93I2D: score=1 
    SCHIP1Q9P0W53I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAM178A (F178A)

    Search CenterWatch for drugs/clinical trials and news about FAM178A / F178A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAM178A gene (4 alternative transcripts): 
    NM_144592.1  NM_001136123.1  NM_001243770.1  NM_018121.3  

    Unigene Cluster for FAM178A:

    Family with sequence similarity 178, member A
    Hs.447458  [show with all ESTs]
    Unigene Representative Sequence: NM_018121
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370271(uc001krr.1 uc001kru.1) ENST00000238961(uc001krt.4)
    ENST00000370269(uc001krs.3) ENST00000481654

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM178A
    8/105 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM178A (see all 105):
    hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-4254 hsa-miR-631 hsa-miR-371-5p hsa-miR-519a hsa-miR-629* hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidFAM178A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FAM178A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM178A
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM178A (see all 11)
    OriGene ORF clones in mouse, rat for FAM178A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): FAM178A (NM_018121)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM178A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM178A
    Sirion Biotech Customized lentivirus for stable overexpression of FAM178A 
                         Customized lentivirus expression plasmids for stable overexpression of FAM178A 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM178A
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM178A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM178A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM178A

    Additional mRNA sequence: 

    AF460991.1 AF460992.1 AK001374.1 AK024283.1 AK292565.1 AL832343.1 AL832383.1 AL833126.1 
    BC015131.1 BC020915.1 BC030565.1 BC047715.1 BC064526.1 BC073832.1 

    13 DOTS entries:

    DT.447779  DT.100024753  DT.403630  DT.428704  DT.121266513  DT.121266531  DT.91816894  DT.92067167 
    DT.100669050  DT.121266456  DT.121266517  DT.100644001  DT.95176762 

    24/203 AceView cDNA sequences (see all 203):

    AU132172 AA570100 NM_018121 BC047715 AI523516 AA379912 AA757128 CK826320 
    BC015131 AU127141 AF460992 CD722156 BQ050508 BF438800 CB045246 W87812 
    AA327526 AA737563 AI951781 AI218321 BM666132 CA390090 AA295307 BC030565 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FAM178A (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^
    SP1:                                                                                      -     -     -                                               -         
    SP2:                                                                                      -     -     -                                               -         
    SP3:                                                                                                  -                                                         
    SP4:                    -     -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 21a · 21b · 21c ^ 22a · 22b · 22c
    SP1:  -           -                     
    SP2:  -                                 
    SP3:                                    
    SP4:                                    
    SP5:  -           -                     


    ECgene alternative splicing isoforms for FAM178A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAM178A expression in normal human tissues (normalized intensities)      FAM178A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAGTGTCG
    FAM178A Expression
    About this image


    FAM178A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Blood (Respiratory System)    fully expand to see all 2 entries
             monocyte-derived macrophage   
     
     Kidney (Urinary System)
             renal vesicle e12.5   
     
     Bone (Muscoskeletal System)
             mandibular prominence tissue e12.5   
     
     Gonad
             XY Germ Cells Testis Cord
     
     Head Mesenchyme (Muscoskeletal System)
             mandibular prominence tissue e12.5   

    See FAM178A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAM178A

    SOURCE GeneReport for Unigene cluster: Hs.447458

    UniProtKB/Swiss-Prot: F178A_HUMAN, Q8IX21
    Tissue specificity: Widely expressed. Expressed at higher level in skeletal muscle and at slightly lower level in
    brain, liver and heart, than in lung, kidney, spleen and thymus

        SABiosciences Custom PCR Arrays for FAM178A
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM178A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM178A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FAM178A gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam178a1 , 5 family with sequence similarity 178, member A1, 5 88(n)1
    85.7(a)1
      19 (38.16 cM)5
    2261511  NM_001081225.11  NP_001074694.11 
     449311195 
    chicken
    (Gallus gallus)
    Aves FAM178A1 family with sequence similarity 178, member A 63.53(n)
    53.36(a)
      423858  XM_421726.3  XP_421726.3 
    lizard
    (Anolis carolinensis)
    Reptilia FAM178A6
    Uncharacterized protein
    29(a)
    1 ↔ 1
    3(39515962-39561966)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.322972 Xenopus laevis transcribed sequences 77.23(n)    BJ098634.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam178a1 family with sequence similarity 178, member A 45.83(n)
    35.08(a)
      100320914  XM_002664123.2  XP_002664169.2 


    ENSEMBL Gene Tree for FAM178A (if available)
    TreeFam Gene Tree for FAM178A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAM178A gene
    FAM178B2  

    FAM178A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/969 SNPs in FAM178A are shown (see all 969)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1468921791,2
    C--102670347(+) CTACAA/TATTGA 3 -- us2k10--------
    rs1168336961,2
    F--102670440(+) GATATA/GAACAC 3 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1880742751,2
    --102670644(+) AAGAAA/GATATT 3 -- us2k10--------
    rs1908164131,2
    --102670822(+) GTACTA/GTAATC 3 -- us2k10--------
    rs1407178661,2
    --102670825(+) CTATAA/TTCCAA 3 -- us2k10--------
    rs1821346561,2
    --102670908(+) TGAATA/CGGATT 3 -- us2k10--------
    rs1879704921,2
    --102670942(+) TTATAC/GTACAG 3 -- us2k10--------
    rs780890081,2
    C,F--102671093(+) TTCTCC/TGCTAT 3 -- us2k11Minor allele frequency- T:0.03NA 120
    rs768419591,2
    C,F--102671118(+) TACCCT/ACTATT 3 -- us2k11Minor allele frequency- A:0.01WA 118
    rs1925986211,2
    --102671191(+) GTGAAC/TGTGAA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for FAM178A (102672326 - 102724893 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for FAM178A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv467443CNV Loss19166990
    nsv831965CNV Loss17160897
    nsv515627CNV Gain+Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM178A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM178A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610348    OMIM disorders: --

    4 diseases for FAM178A:    About MalaCards
    infantile onset spinocerebellar ataxia    spinocerebellar ataxia    ataxia    alzheimer's disease


    FAM178A for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): FAM178A
    Human Genome Epidemiology (HuGE) Navigator: FAM178A (1 document)

    Export disorders for FAM178A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAM178A gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with FAM178A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia. (PubMed id 12459258)1, 2, 3, 9 Nikali K.... Peltonen L. (2002)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
    10. Scanning the human proteome for calmodulin-binding pr oteins. (PubMed id 15840729)1 Shen X....Liu R. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55719 HGNC: 17814 AceView: C10orf6 Ensembl:ENSG00000119906 euGenes: HUgn55719
    ECgene: FAM178A H-InvDB: FAM178A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAM178A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FAM178A gene:
    Search GeneIP for patents involving FAM178A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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