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FAM175B Gene

protein-coding   GIFtS: 50
GCID: GC10P126481

Family With Sequence Similarity 175, Member B

(Previous name: KIAA0157)
(Previous symbol: KIAA0157)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 175, Member B1 2     Abraxas Brother1
KIAA01571 2 3 5     Abraxas Brother 12
ABRO12 3 5     BRISC Complex Subunit Abro12
Abraxas Brother Protein 12 3     Protein FAM175B3

External Ids:    HGNC: 289751   Entrez Gene: 231722   Ensembl: ENSG000001656607   OMIM: 6111445   UniProtKB: Q150183   

Export aliases for FAM175B gene to outside databases

Previous GC identifer: GC10P120177


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM175B Gene:
FAM175B (family with sequence similarity 175, member B) is a protein-coding gene. GO annotations related to this gene include polyubiquitin binding. An important paralog of this gene is FAM175A.

UniProtKB/Swiss-Prot: F175B_HUMAN, Q15018
Function: Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked
ubiquitin. May act as a central scaffold protein that assembles the various components of the BRISC complex

Gene Wiki entry for FAM175B (KIAA0157) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM175B gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   E2F   E2F-1   POU2F1   FOXO4   POU2F1a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM175B promoter sequence
   Search Chromatin IP Primers for FAM175B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM175B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.13   Ensembl cytogenetic band:  10q26.13   HGNC cytogenetic band: 10q26.2

FAM175B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM175B gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P126481:  view genomic region     (about GC identifiers)

Start:
126,490,354 bp from pter      End:
126,525,239 bp from pter
Size:
34,886 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: F175B_HUMAN, Q15018 (See protein sequence)
Recommended Name: BRISC complex subunit Abro1  
Size: 415 amino acids; 46901 Da
Subunit: Component of the BRISC complex, at least composed of the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and
BABAM1/NBA1. Does not interact with BRCA1. Binds polyubiquitin
Caution: Although strongly related to the FAM175A/CCDC98 protein, lacks the C-terminal pSXXF that constitutes a
specific recognition motif for the BRCT domain of BRCA1
Sequence caution: Sequence=BAA09927.1; Type=Erroneous initiation;
Secondary accessions: B4DKR2 Q96H11

Explore the universe of human proteins at neXtProt for FAM175B: NX_Q15018

Explore proteomics data for FAM175B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM175B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115558.3  
    ENSEMBL proteins: 
     ENSP00000298492  

    FAM175B Human Recombinant Protein Products:

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    Novus Biologicals FAM175B Protein
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    Cloud-Clone Corp. Proteins for FAM175B

     
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    LSBio Antibodies in human, mouse, rat for FAM175B

    FAM175B Assay Products:

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    Cloud-Clone Corp. ELISAs for FAM175B
    Cloud-Clone Corp. CLIAs for FAM175B
    Search eBioscience for ELISAs for FAM175B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR023240 FAM175_BRISC_cplx_Abro1_su
     IPR023238 FAM175

    Graphical View of Domain Structure for InterPro Entry Q15018

    ProtoNet protein and cluster: Q15018

    UniProtKB/Swiss-Prot: F175B_HUMAN, Q15018
    Domain: The MPN-like region is similar to the MPN (JAB/Mov34) domain
    Similarity: Belongs to the FAM175 family. Abro1 subfamily


    Find genes that share domains with FAM175B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: F175B_HUMAN, Q15018
    Function: Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked
    ubiquitin. May act as a central scaffold protein that assembles the various components of the BRISC complex

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031593polyubiquitin binding IDA19261749
         
    Find genes that share ontologies with FAM175B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FAM175B:
     Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM175B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM175B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM175B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM175B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM175B:
    hsa-mir-124-3p (MIRT022599), hsa-mir-183-5p (MIRT047107)

    Block miRNA regulation of human, mouse, rat FAM175B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM175B (see all 57):
    hsa-miR-520e hsa-miR-302d hsa-miR-411 hsa-miR-301a hsa-miR-449a hsa-miR-519a hsa-miR-218 hsa-miR-372
    SwitchGear 3'UTR luciferase reporter plasmidFAM175B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM175B

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: FAM175B (NM_032182)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM175B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM175B
    Addgene plasmids for FAM175B 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM175B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1
    extracellular1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070552BRISC complex IDA19214193

    Find genes that share ontologies with FAM175B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM175B
    Interactions:

        Search GeneGlobe Interaction Network for FAM175B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for FAM175B (Q150182, 3 ENSP000002984924) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMURF2Q9HAU42, 3MINT-61798 I2D: score=3 
    BREQ9NXR73, ENSP000003434124I2D: score=3 STRING: ENSP00000343412
    BABAM1Q9NWV83, ENSP000003524084I2D: score=2 STRING: ENSP00000352408
    UIMC1Q96RL13, ENSP000003664344I2D: score=2 STRING: ENSP00000366434
    BRCC3P467363, ENSP000003819984I2D: score=2 STRING: ENSP00000381998
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM175B (F175B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM175B gene: 
    NM_032182.3  

    Unigene Cluster for FAM175B:

    Family with sequence similarity 175, member B
    Hs.280695  [show with all ESTs]
    Unigene Representative Sequence: NM_032182
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000298492(uc001lib.4)
    miRNA
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    Block miRNA regulation of human, mouse, rat FAM175B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM175B (see all 57):
    hsa-miR-520e hsa-miR-302d hsa-miR-411 hsa-miR-301a hsa-miR-449a hsa-miR-519a hsa-miR-218 hsa-miR-372
    SwitchGear 3'UTR luciferase reporter plasmidFAM175B 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for FAM175B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM175B
    Clone
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    GenScript: all cDNA clones in your preferred vector: FAM175B (NM_032182)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM175B
    Addgene plasmids for FAM175B 
    Primer
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    OriGene qPCR primer pairs and template standards for FAM175B
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM175B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM175B
      QuantiTect SYBR Green Assays in human, mouse, rat FAM175B
      QuantiFast Probe-based Assays in human, mouse, rat FAM175B

    Additional mRNA sequence: 

    AK025991.1 AK296677.1 BC008999.1 D63877.1 

    6 DOTS entries:

    DT.316831  DT.95166138  DT.102823957  DT.40203606  DT.92018776  DT.95182665 

    Selected AceView cDNA sequences (see all 136):

    CA390149 BM728970 BU176241 D31384 R96624 AU122659 NM_032182 CB215227 
    BI063476 BQ440855 AA453925 BX425308 AA361800 BU170386 CN481607 AI431779 
    AA278200 AW949485 BG110364 AI537680 BC008999 BP342101 AA700670 BX280523 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM175B (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9
    SP1:        -           -           -                                             
    SP2:        -           -           -                                             
    SP3:        -           -     -     -                                             
    SP4:                    -           -                                             
    SP5:                                -                                             


    ECgene alternative splicing isoforms for FAM175B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM175B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAGGAGTG
    FAM175B Expression
    About this image

    FAM175B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM175B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.280695
        Custom PCR Arrays for FAM175B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM175B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FAM175B gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam175b1 , 5 family with sequence similarity 175, member B1, 5 90.44(n)1
    93.49(a)1
      7 (76.32 cM)5
    1093591  NM_198017.31  NP_932134.31 
     1328592255 
    chicken
    (Gallus gallus)
    Aves FAM175B1 family with sequence similarity 175, member B 81.74(n)
    85.51(a)
      423954  NM_001031241.1  NP_001026412.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM175B6
    family with sequence similarity 175, member B
    76(a)
    1 ↔ 1
    3(62148168-62185825)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC3947642 hypothetical protein LOC394764 76.77(n)    BC063225.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005383401 BRISC complex subunit Abro1-like 67.26(n)
    70.41(a)
      100538340  XM_003200355.2  XP_003200403.1 


    ENSEMBL Gene Tree for FAM175B (if available)
    TreeFam Gene Tree for FAM175B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM175B gene
    FAM175A2  
    1 SIMAP similar gene for FAM175B using alignment to 1 protein entry:     F175B_HUMAN:
    FAM175A

    Find genes that share paralogs with FAM175B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM175B (see all 678)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1925427351,2
    --120175342(+) GCACTC/GTAAGA 1 -- us2k10--------
    rs1141084261,2
    C,F--120175348(+) TAAGAC/TGTTTA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1457715951,2
    --120175359(+) GCCACC/TTCTCT 1 -- us2k10--------
    rs1836037881,2
    --120175440(+) CATTGC/TCACAT 1 -- us2k10--------
    rs1883676831,2
    --120175455(+) TTTTGA/GGAGGC 1 -- us2k10--------
    rs1481868921,2
    --120175472(+) GCCACC/GAGTTC 1 -- us2k10--------
    rs1415859431,2
    C--120175518(+) GAGAGA/GGATGA 1 -- us2k10--------
    rs109018231,2
    C,F,A,H--120175595(+) AAAGTG/AATTGT 1 -- us2k125Minor allele frequency- A:0.46NS EA NA WA 2706
    rs1811379921,2
    --120175799(+) CATGCC/TTCAGC 1 -- us2k10--------
    rs1849134631,2
    --120175966(+) CATATA/CCCCTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FAM175B (126490354 - 126525239 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FAM175B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660881CNV Deletion23128226
    nsv832014CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM175B
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM175B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611144    OMIM disorders: --


    Find genes that share disorders with FAM175B           About GenesLikeMe

    Genetic Association Database (GAD): FAM175B

    Export disorders for FAM175B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM175B gene, integrated from 10 sources (see all 32):
    (articles sorted by number of sources associating them with FAM175B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2, 3 Nagase T.... Nomura N. (DNA Res. 1995)
    2. NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. (PubMed id 19261749)1, 2 Wang B.... Elledge S.J. (Genes Dev. 2009)
    3. K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1. (PubMed id 19214193)1, 2 Cooper E.M....Cohen R.E. (EMBO J. 2009)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (Anal. Chem. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    8. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (EMBO J. 2013)
    9. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23172 HGNC: 28975 AceView: KIAA0157 Ensembl:ENSG00000165660 euGenes: HUgn23172
    ECgene: FAM175B H-InvDB: FAM175B

    (According to HUGE)
    About This Section

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    HUGE: KIAA0157

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FAM175B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FAM175B gene:
    Search GeneIP for patents involving FAM175B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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