FAM173A Gene
protein-coding GIFtS: 40
GCID: GC16P000770
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family with sequence similarity 173, member A(Previous name: chromosome 16 open reading frame 24 )
(Previous symbol: C16orf24)
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Aliases
for FAM173A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 173, Member A1 2 | | C16orf241 2 3 | | MGC24941 | | Chromosome 16 Open Reading Frame 241 | | Protein FAM173A2 |
Export aliases for FAM173A gene to outside databasesPrevious GC identifers: GC16P000713 GC16P000771 GC16P000693 |
Summaries
for FAM173A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM173A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM173A gene promoter:
USF1 FOXF2 AML1a AP-1 XBP-1 c-Ets-1 USF-1 Zic1 c-Myb Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM173A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM173A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3FAM173A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P000770: view genomic region
(about GC identifiers)
Start:
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770,581 bp from pter |
End:
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772,601 bp from pter |
Size:
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2,021 bases |
Orientation:
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plus strand |
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Proteins
for FAM173A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F173A_HUMAN, Q9BQD7 (See
protein sequence)Recommended Name: Protein FAM173A Size: 235 amino acids; 25130 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: A2IDD4Explore the universe of human proteins at neXtProt for FAM173A: NX_Q9BQD7
FAM173A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001258214.1 NP_076422.1
ENSEMBL proteins: ENSP00000454380 ENSP00000455283 ENSP00000219535 ENSP00000455962
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
FAM173A for ontologies About GeneDecksing
FAM173A Antibody Products:
Assay Products for FAM173A: |
Protein
Domains /
Families
for FAM173A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM173A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BQD7ProtoNet protein and cluster: Q9BQD7 UniProtKB/Swiss-Prot: F173A_HUMAN, Q9BQD7Similarity: Belongs to the FAM173 family |
Function
for FAM173A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM173A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM173A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM173A (NM_023933) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM173A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM173A |
1 GenomeRNAi human phenotype for FAM173A:
|
Pathways & Interactions
for FAM173A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM173A
5/10 Interacting proteins for FAM173A (Q9BQD73) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
|
Drugs & Compounds
for FAM173A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM173A
Search CenterWatch for drugs/clinical trials and news about FAM173A / F173A
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Transcripts
for FAM173A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM173A gene (2 alternative transcripts): NM_001271285.1 NM_023933.2 Unigene Cluster for FAM173A: Family with sequence similarity 173, member A Hs.166244 [show with all ESTs]Unigene Representative Sequence: BM9236668 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000566525 ENST00000569529(uc002cje.3) ENST00000564000 ENST00000219535
ENST00000564640 ENST00000566437 ENST00000568916 ENST00000570237
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM173A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM173A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM173A (NM_023933) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM173A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM173A |
Additional cDNA sequence: AK123186.1 BC001181.1 BC002624.2 9 DOTS entries: DT.435614 DT.101977247 DT.95166073 DT.95166076 DT.92423317 DT.92423316 DT.92423320 DT.92423318 DT.95166078 24/70 AceView cDNA sequences (see all 70): BM311593 BF444999 BC002624 CK821575 BM924050 BE302688 AK123186 BE207519 CK821576 AW614069 AI655597 BE504113 AI816922 AI703441 BE797298 BX454559 BF981749 BE389922 BE619405 BU632070 BI838160 AI952735 CA432424 BI836832
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FAM173A (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | · | 4c |
|---|
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| SP1: | | | | | | | | | - | | | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | - | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM173A
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Expression
for FAM173A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM173A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGCAGGACG
About this image
See FAM173A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM173A
SOURCE GeneReport for Unigene cluster: Hs.166244
SABiosciences Custom PCR Arrays for FAM173A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM173A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM173A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM173A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM173A |
Orthologs
for FAM173A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FAM173A gene from 5/20 species (see all 20) About this table
ENSEMBL Gene Tree for FAM173A (if available)
TreeFam Gene Tree for FAM173A (if available) |
Paralogs
for FAM173A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM173A gene
- FAM173B2
1 SIMAP similar gene for FAM173A using alignment to 4 protein entries: F173A_HUMAN (see all proteins):FAM173B
FAM173A for paralogs About GeneDecksing
|
Genomic Variants
for FAM173A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM173A (770581 - 772601 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for FAM173A
9 CNVs: 49738 49727 29986 49728 3987 29982 5329 30732 29983 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM173A |
|
Disorders
/ Diseases
for FAM173A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM173A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM173A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM173A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (2001)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM173A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM173A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM173A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM173A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM173A | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM173A gene:
Search GeneIP for patents involving FAM173A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM173A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM173A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM173A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM173A | | | OriGene Protein Over-expression Lysate for FAM173A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM173A | | OriGene 3'-UTR Clone for FAM173A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM173A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM173A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM173A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM173A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM173A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM173A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM173A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM173A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM173A |
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 | | | FAM173A Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for FAM173A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM173A |
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