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Aliases for FAM173A Gene

Aliases for FAM173A Gene

  • Family With Sequence Similarity 173 Member A 2 3 5
  • Family With Sequence Similarity 173, Member A 2 3
  • C16orf24 3 4
  • Chromosome 16 Open Reading Frame 24 2

External Ids for FAM173A Gene

Previous HGNC Symbols for FAM173A Gene

  • C16orf24

Previous GeneCards Identifiers for FAM173A Gene

  • GC16P000713
  • GC16P000771
  • GC16P000693
  • GC16P000770
  • GC16P000819
  • GC16P000863

Summaries for FAM173A Gene

GeneCards Summary for FAM173A Gene

FAM173A (Family With Sequence Similarity 173 Member A) is a Protein Coding gene. An important paralog of this gene is FAM173B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM173A Gene

Genomics for FAM173A Gene

Regulatory Elements for FAM173A Gene

Enhancers for FAM173A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM173A on UCSC Golden Path with GeneCards custom track

Promoters for FAM173A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM173A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM173A Gene

720,581 bp from pter
722,601 bp from pter
2,021 bases
Plus strand

Genomic View for FAM173A Gene

Genes around FAM173A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM173A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM173A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM173A Gene

Proteins for FAM173A Gene

  • Protein details for FAM173A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM173A
    Protein Accession:
    Secondary Accessions:
    • A2IDD4

    Protein attributes for FAM173A Gene

    235 amino acids
    Molecular mass:
    25130 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM173A Gene

Proteomics data for FAM173A Gene at MOPED

Post-translational modifications for FAM173A Gene

  • Glycosylation at Asn 144
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM173A Gene

No data available for DME Specific Peptides for FAM173A Gene

Domains & Families for FAM173A Gene

Protein Domains for FAM173A Gene


Suggested Antigen Peptide Sequences for FAM173A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM173 family.
  • Belongs to the FAM173 family.
genes like me logo Genes that share domains with FAM173A: view

No data available for Gene Families for FAM173A Gene

Function for FAM173A Gene

genes like me logo Genes that share phenotypes with FAM173A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM173A Gene

Localization for FAM173A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM173A Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FAM173A Gene COMPARTMENTS Subcellular localization image for FAM173A gene
Compartment Confidence
cytosol 3
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for FAM173A Gene

Pathways & Interactions for FAM173A Gene

SuperPathways for FAM173A Gene

No Data Available

Interacting Proteins for FAM173A Gene

Gene Ontology (GO) - Biological Process for FAM173A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM173A Gene

Drugs & Compounds for FAM173A Gene

No Compound Related Data Available

Transcripts for FAM173A Gene

Unigene Clusters for FAM173A Gene

Family with sequence similarity 173, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM173A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c
SP1: - - -
SP2: - - - -
SP3: - -
SP4: - - -
SP5: -
SP6: -
SP7: - -

Relevant External Links for FAM173A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM173A Gene

mRNA expression in normal human tissues for FAM173A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM173A Gene

SOURCE GeneReport for Unigene cluster for FAM173A Gene Hs.166244

genes like me logo Genes that share expression patterns with FAM173A: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM173A Gene

Orthologs for FAM173A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM173A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM173A 35
  • 86.61 (n)
  • 88.39 (a)
FAM173A 36
  • 88 (a)
(Mus musculus)
Mammalia Fam173a 35
  • 78.37 (n)
  • 81.33 (a)
Fam173a 16
Fam173a 36
  • 79 (a)
(Pan troglodytes)
Mammalia FAM173A 35
  • 98.87 (n)
  • 97.45 (a)
FAM173A 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Fam173a 35
  • 79.73 (n)
  • 84.68 (a)
(Monodelphis domestica)
Mammalia FAM173A 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia FAM173A 36
  • 67 (a)
(Gallus gallus)
Aves FAM173A 35
  • 66.67 (n)
  • 60.7 (a)
FAM173A 36
  • 57 (a)
(Anolis carolinensis)
Reptilia FAM173A 36
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam173a 35
  • 66.5 (n)
  • 66.33 (a)
(Danio rerio)
Actinopterygii fam173a 35
  • 55.56 (n)
  • 57.75 (a)
fam173a 36
  • 57 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3337 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea Y39A1A.21 36
  • 33 (a)
Species with no ortholog for FAM173A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM173A Gene

Gene Tree for FAM173A (if available)
Gene Tree for FAM173A (if available)

Paralogs for FAM173A Gene

Paralogs for FAM173A Gene

(1) SIMAP similar genes for FAM173A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM173A: view

Variants for FAM173A Gene

Sequence variations from dbSNP and Humsavar for FAM173A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs743987 -- 719,566(+) AGGCC(C/G)AGGCA upstream-variant-2KB
rs763206 -- 720,103(+) GTCTG(C/G)GGCAT upstream-variant-2KB
rs62032513 -- 720,487(+) CTTCT(C/T)GGGCC upstream-variant-2KB
rs62032514 -- 721,817(+) CCACA(G/T)GTGCG nc-transcript-variant, reference, missense
rs9935634 -- 720,601(+) GGAGG(A/G)AAATG nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM173A Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
nsv904707 CNV Loss 21882294
nsv526903 CNV Loss 19592680
dgv2475n71 CNV Loss 21882294
dgv2479n71 CNV Loss 21882294
nsv471063 CNV Loss 18288195
dgv2485n71 CNV Loss 21882294
nsv904759 CNV Loss 21882294
nsv516590 CNV Loss 19592680
dgv2488n71 CNV Loss 21882294
nsv904781 CNV Gain 21882294
nsv471065 CNV Gain 18288195
dgv2490n71 CNV Loss 21882294
nsv9321 CNV Gain+Loss 18304495
dgv2491n71 CNV Loss 21882294
nsv904796 CNV Loss 21882294
nsv904797 CNV Loss 21882294
dgv2492n71 CNV Loss 21882294
nsv457311 CNV Loss 19166990
dgv2495n71 CNV Loss 21882294
nsv904812 CNV Loss 21882294
dgv2496n71 CNV Loss 21882294
dgv2497n71 CNV Loss 21882294

Variation tolerance for FAM173A Gene

Gene Damage Index Score: 3.27; 52.94% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM173A Gene

Disorders for FAM173A Gene

Relevant External Links for FAM173A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM173A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM173A Gene

Publications for FAM173A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 3

Products for FAM173A Gene

Sources for FAM173A Gene