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FAM172A Gene

protein-coding   GIFtS: 51
GCID: GC05M092981

Family With Sequence Similarity 172, Member A

(Previous name: chromosome 5 open reading frame 21)
(Previous symbol: C5orf21)
  See FAM172A-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 172, Member A1 2
C5orf211 2 3
Chromosome 5 Open Reading Frame 211
Protein FAM172A2

External Ids:    HGNC: 253651   Entrez Gene: 839892   Ensembl: ENSG000001133917   UniProtKB: Q8WUF83   

Export aliases for FAM172A gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM172A Gene:
FAM172A (family with sequence similarity 172, member A) is a protein-coding gene. Diseases associated with FAM172A include diabetic angiopathy.

Gene Wiki entry for FAM172A (C5orf21) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_034772.7  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM172A gene promoter:
         STAT1   p300   STAT1beta   STAT1alpha   AREB6   CP2   FOXJ2 (long isoform)   STAT3   PPAR-gamma2   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM172A promoter sequence
   Search Chromatin IP Primers for FAM172A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM172A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q15   Ensembl cytogenetic band:  5q15   HGNC cytogenetic band: 5q15

FAM172A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM172A gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M092981:  view genomic region     (about GC identifiers)

Start:
92,953,431 bp from pter      End:
93,447,404 bp from pter
Size:
493,974 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: F172A_HUMAN, Q8WUF8 (See protein sequence)
Recommended Name: Protein FAM172A precursor  
Size: 416 amino acids; 47972 Da
Secondary accessions: B2R7C6 B4DJ14 B4DLG5 Q9H0U8
Alternative splicing: 4 isoforms:  Q8WUF8-1   Q8WUF8-2   Q8WUF8-3   Q8WUF8-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM172A: NX_Q8WUF8

Explore proteomics data for FAM172A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys35, Lys333
  • Modification sites at PhosphoSitePlus

  • See FAM172A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001156889.1  NP_001156890.1  NP_114431.2  

    ENSEMBL proteins: 
     ENSP00000379294   ENSP00000426284   ENSP00000421834   ENSP00000423841   ENSP00000424097  

    FAM172A Human Recombinant Protein Products:

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    Novus Biologicals FAM172A Lysate
    Browse Sino Biological Recombinant Proteins
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM172A

     
    Search eBioscience for Proteins for FAM172A 

     
    antibodies-online proteins for FAM172A (8 products) 

     
    antibodies-online peptides for FAM172A

    FAM172A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    LSBio Antibodies in human, mouse, rat for FAM172A
    antibodies-online antibodies for FAM172A (7 products) 

    FAM172A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for FAM172A
    Cloud-Clone Corp. CLIAs for FAM172A
    Search eBioscience for ELISAs for FAM172A 
    antibodies-online kits for FAM172A (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019154 Arb2_domain

    Graphical View of Domain Structure for InterPro Entry Q8WUF8

    ProtoNet protein and cluster: Q8WUF8

    UniProtKB/Swiss-Prot: F172A_HUMAN, Q8WUF8
    Similarity: Belongs to the UPF0528 family


    Find genes that share domains with FAM172A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM172A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM172A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM172A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM172A

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM172A:
    hsa-mir-421 (MIRT039397)

    Block miRNA regulation of human, mouse, rat FAM172A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM172A (see all 40):
    hsa-miR-576-3p hsa-miR-1914* hsa-miR-513a-5p hsa-miR-128 hsa-miR-218 hsa-miR-548l hsa-miR-3171 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidFAM172A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM172A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM172A

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for FAM172A

    Clone
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    OriGene clones in human, mouse for FAM172A (see all 20)
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    GenScript: all cDNA clones in your preferred vector (see all 3): FAM172A (NM_032042)
    Sino Biological Human cDNA Clone for FAM172A
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM172A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM172A

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM172A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    F172A_HUMAN, Q8WUF8: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    extracellular3
    cytosol1
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005783endoplasmic reticulum IDA--

    Find genes that share ontologies with FAM172A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM172A
    Interactions:

        Search GeneGlobe Interaction Network for FAM172A

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for FAM172A (Q8WUF83 ENSP000003792944) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    B4GALT1P152913I2D: score=1 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM172A (F172A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM172A gene (3 alternative transcripts): 
    NM_001163417.1  NM_001163418.1  NM_032042.5  

    Unigene Cluster for FAM172A:

    Family with sequence similarity 172, member A
    Hs.600086  [show with all ESTs]
    Unigene Representative Sequence: NM_032042
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000395965(uc010jbd.3 uc011cuf.2 uc011cug.2 uc011cuh.2 uc011cui.2 uc011cuj.2)
    ENST00000505869 ENST00000509739 ENST00000509163 ENST00000502503 ENST00000511139
    ENST00000510445 ENST00000506398(uc003kkm.4) ENST00000504768
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM172A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM172A (see all 40):
    hsa-miR-576-3p hsa-miR-1914* hsa-miR-513a-5p hsa-miR-128 hsa-miR-218 hsa-miR-548l hsa-miR-3171 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidFAM172A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM172A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM172A
    Clone
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    OriGene clones in human, mouse for FAM172A (see all 20)
    OriGene ORF clones in mouse, rat for FAM172A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): FAM172A (NM_032042)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM172A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM172A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAM172A
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM172A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM172A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM172A
      QuantiFast Probe-based Assays in human, mouse, rat FAM172A

    Additional mRNA sequence: 

    AF070617.1 AK295127.1 AK295879.1 AK296683.1 AK296986.1 AK297471.1 AK309742.1 AK312930.1 
    AL136630.1 BC012007.1 BC020584.2 NR_028080.1 

    13 DOTS entries:

    DT.100025788  DT.114145  DT.95158760  DT.100788474  DT.120876442  DT.40227808  DT.100718923  DT.100788469 
    DT.120876360  DT.120876435  DT.91754400  DT.91754401  DT.97815055 

    Selected AceView cDNA sequences (see all 147):

    AA947660 BQ929402 BC020584 AA133896 BM801927 AI554298 BM676590 BM980381 
    CB215800 BQ188207 BM789633 CB052434 AI637652 BX425619 BX279883 BI916568 
    AI868466 BX280740 AW958085 AI224844 CR605117 BM555117 BQ720126 AA603316 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for FAM172A    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                    -     -                 -                                         -         
    SP2:                                                                                                
    SP3:                                                                                                
    SP4:                                                                                                


    ECgene alternative splicing isoforms for FAM172A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM172A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCTTTAAT
    FAM172A Expression
    About this image

    FAM172A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM172A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.600086
        Custom PCR Arrays for FAM172A
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat FAM172A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM172A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM172A gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam172a1 , 5 family with sequence similarity 172, member A1, 5 89.63(n)1
    93.33(a)1
      13 (41.29 cM)5
    686751  NM_138312.11  NP_612185.11 
     777086905 
    chicken
    (Gallus gallus)
    Aves FAM172A1 family with sequence similarity 172, member A 82.76(n)
    89.11(a)
      427109  NM_001006574.1  NP_001006574.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM172A6
    family with sequence similarity 172, member A
    86(a)
    1 ↔ 1
    2(24977991-25165110)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fam172a1 family with sequence similarity 172, member A 76.58(n)
    83.25(a)
      448398  NM_001004971.1  NP_001004971.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc641882 hypothetical protein MGC64188 77.07(n)   393390  BC054635.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG100381 CG10038 47.07(n)
    41.2(a)
      41495  NM_169460.2  NP_731685.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y75B8A.311 CELE_Y75B8A.31 48.93(n)
    40.38(a)
      176658  NM_067203.5  NP_499604.1 


    ENSEMBL Gene Tree for FAM172A (if available)
    TreeFam Gene Tree for FAM172A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM172A gene
    1 SIMAP similar gene for FAM172A using alignment to 3 protein entries:     F172A_HUMAN (see all proteins):
    FAM172BP

    Find genes that share paralogs with FAM172A           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for FAM172A
    PGOHUM00000250295


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM172A (see all 7152)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs586199121,2
    C--88170434(+) AAAAA-/AA/AAA
            
    TCACA
    4 -- int11NA 2
    rs347844231,2
    C,F--88621726(+) CAGTT-/AAAGTCA 4 -- us2k13Minor allele frequency- AA:0.33NA CSA 6
    rs1460085671,2
    --92953148(+) TACTCG/TTTCTT 4 -- ds50010--------
    rs1487360781,2
    --92953176(+) AGACAC/GCAACA 4 -- ds50010--------
    rs1414752221,2
    --92953198(+) GTTTAC/TAGTAA 4 -- ds50010--------
    rs1152553271,2
    F--92953231(+) CACACG/ATGTTT 4 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1851497521,2
    --92953240(+) TTGGAC/TTGAAC 4 -- ds50010--------
    rs614293251,2
    C,F--92953248(+) AACCGC/TAGATA 4 -- ds50018Minor allele frequency- T:0.19WA NA CSA EA 367
    rs1508130041,2
    --92953353(+) GAAATA/GTAAGT 4 -- ds50010--------
    rs747159841,2
    C--92953468(+) TTCAAC/GTGTAT 4 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for FAM172A (92953431 - 93203431 bp, first 250kb of FAM172A)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for FAM172A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2730468CNV Deletion23290073
    esv2730469CNV Deletion23290073
    esv2664180CNV Deletion23128226
    esv2730466CNV Deletion23290073
    esv2730467CNV Deletion23290073
    nsv823133CNV Loss20364138
    nsv830405CNV Loss17160897
    nsv830404CNV Loss17160897
    nsv882384CNV Loss21882294
    dgv954n67CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM172A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM172A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for FAM172A:    
    About MalaCards
    diabetic angiopathy

    1 disease from the University of Copenhagen DISEASES database for FAM172A:
    Diabetic angiopathy

    Find genes that share disorders with FAM172A           About GenesLikeMe

    Genetic Association Database (GAD): FAM172A
    Human Genome Epidemiology (HuGE) Navigator: FAM172A (1 document)

    Export disorders for FAM172A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM172A gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with FAM172A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    5. [Effect of FAM172A protein on apoptosis and proliferation in HEK293 cells]. (PubMed id 21092515)1 Li L.X....Hu R.M. (Zhonghua Yi Xue Za Zhi 2010)
    6. Identification of the novel protein FAM172A, and its up-regulation by high glucose in human aortic smooth muscle cells. (PubMed id 20818486)1 Li L....Hu R. (Int. J. Mol. Med. 2010)
    7. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    9. [Molecular cloning of a novel gene, C5orf21 gene and its roles in diabetic macroangiopathy]. (PubMed id 20137623)1 Li L.X....Hu R.M. (Zhonghua Yi Xue Za Zhi 2009)
    10. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83989 HGNC: 25365 AceView: DKFZP564D172 Ensembl:ENSG00000113391 euGenes: HUgn83989
    ECgene: FAM172A H-InvDB: FAM172A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM172A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM172A gene:
    Search GeneIP for patents involving FAM172A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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