FAM171A1 Gene
protein-coding GIFtS: 44
GCID: GC10M015254
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family with sequence similarity 171, member A1(Previous name: chromosome 10 open reading frame 38 )
(Previous symbol: C10orf38)
| |
Aliases
for FAM171A1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 171, Member A11 2 | | Astroprincin3 | | C10orf381 2 3 | | Protein FAM171A12 | | FLJ128841 | | Astroprincin3 | | Chromosome 10 Open Reading Frame 381 | | |
Export aliases for FAM171A1 gene to outside databasesPrevious GC identifers: GC10M015294 GC10M015167 |
Summaries
for FAM171A1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM171A1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM171A1 gene promoter:
Egr-3 HNF-3beta AP-2gamma NF-AT MEF-2A NF-AT2 NF-AT3 Sox9 aMEF-2 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM171A1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM171A1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p13 Ensembl cytogenetic band: 10p13 HGNC cytogenetic band: 10p13FAM171A1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M015254: view genomic region
(about GC identifiers)
Start:
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15,253,642 bp from pter |
End:
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15,413,061 bp from pter |
Size:
|
159,420 bases |
Orientation:
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minus strand |
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Proteins
for FAM171A1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F1711_HUMAN, Q5VUB5 (See
protein sequence)Recommended Name: Protein FAM171A1 precursor Size: 890 amino acids; 97854 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: D3DRT9 Q32M49 Q8N4I0Explore the universe of human proteins at neXtProt for FAM171A1: NX_Q5VUB5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5VUB5
FAM171A1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001010924.1
ENSEMBL proteins: ENSP00000367356 ENSP00000407796
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
FAM171A1 for ontologies About GeneDecksing
FAM171A1 Antibody Products:
Assay Products for FAM171A1: |
Protein
Domains /
Families
for FAM171A1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM171A1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5VUB5ProtoNet protein and cluster: Q5VUB5 UniProtKB/Swiss-Prot: F1711_HUMAN, Q5VUB5Similarity: Belongs to the FAM171 family |
Function
for FAM171A1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM171A1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM171A1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM171A1 (NM_001010924) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM171A1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM171A1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM171A1 |
|
Pathways & Interactions
for FAM171A1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM171A1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/9 Interacting proteins for FAM171A1 (Q5VUB53 ENSP000003673564) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
|
Drugs & Compounds
for FAM171A1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM171A1
Search CenterWatch for drugs/clinical trials and news about FAM171A1 / F1711
|
Transcripts
for FAM171A1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM171A1 gene: NM_001010924.1 Unigene Cluster for FAM171A1: Family with sequence similarity 171, member A1 Hs.66762 [show with all ESTs]Unigene Representative Sequence: AY6830033 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000378116(uc001iob.3) ENST00000477161 ENST00000455654
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM171A1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM171A1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM171A1 (NM_001010924) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM171A1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM171A1 |
Additional cDNA sequence: AK022946.1 AL050367.1 AY683003.1 BC034232.1 BC089427.1 BC109302.1 BC109303.1 10 DOTS entries: DT.315902 DT.121263523 DT.100035970 DT.121263471 DT.100764189 DT.121263494 DT.121263518 DT.434859 DT.95171018 DT.91880414 24/147 AceView cDNA sequences (see all 147): AU130409 AI476280 AI378812 BM663588 AA029581 BM052718 AA404359 AA035775 AA056336 BI913133 CB143172 AL038660 AI022579 AI565123 BE504865 AW235877 BM052992 BE883250 BQ644435 AK022946 CK903934 BF448756 BM052713 BE677452
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for FAM171A1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b |
|---|
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| SP1: | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM171A1
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Expression
for FAM171A1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM171A1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTAACGTGG
About this image
See FAM171A1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM171A1
SOURCE GeneReport for Unigene cluster: Hs.66762
SABiosciences Custom PCR Arrays for FAM171A1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM171A1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM171A1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM171A1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM171A1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM171A1 |
Orthologs
for FAM171A1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM171A1 gene from 5/12 species (see all 12) About this table
ENSEMBL Gene Tree for FAM171A1 (if available)
TreeFam Gene Tree for FAM171A1 (if available) |
Paralogs
for FAM171A1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM171A1 gene
- FAM171B2 FAM171A22
4 SIMAP similar genes for FAM171A1 using alignment to 3 protein entries: F1711_HUMAN (see all proteins):C10orf38 FAM171B KIAA1946 FAM171A2
FAM171A1 for paralogs About GeneDecksing
|
Genomic Variants
for FAM171A1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM171A1 (15253642 - 15413061 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for FAM171A1
1 CNV: 100874
3 Indels: 44710 24434 42019 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM171A1 |
|
Disorders
/ Diseases
for FAM171A1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM171A1 for disorders About MalaCards
FAM171A1 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: FAM171A1 (1 document)
Export disorders for FAM171A1 gene to outside databases
|
Publications
for FAM171A1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM171A1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM171A1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
- Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography. (PubMed id 18318008)2 Han G.... Gu J. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for FAM171A1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM171A1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM171A1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM171A1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM171A1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM171A1 gene:
Search GeneIP for patents involving FAM171A1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM171A1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM171A1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM171A1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM171A1 | | | OriGene Protein Over-expression Lysate for FAM171A1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM171A1 | | OriGene 3'-UTR Clone for FAM171A1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM171A1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM171A1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM171A1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM171A1 | | OriGene Custom Protein Services for FAM171A1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM171A1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM171A1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM171A1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM171A1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM171A1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM171A1 |
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 | | | FAM171A1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM171A1 |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM171A1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM171A1 |
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