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Aliases for FAM169B Gene

Aliases for FAM169B Gene

  • Family With Sequence Similarity 169, Member B 2 3
  • KIAA0888L 4

External Ids for FAM169B Gene

Previous GeneCards Identifiers for FAM169B Gene

  • GC15M096797
  • GC15M098980
  • GC15M075108

Summaries for FAM169B Gene

GeneCards Summary for FAM169B Gene

FAM169B (Family With Sequence Similarity 169, Member B) is a Protein Coding gene. An important paralog of this gene is FAM169A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM169B Gene

Genomics for FAM169B Gene

Regulatory Elements for FAM169B Gene

Genomic Location for FAM169B Gene

98,437,162 bp from pter
98,514,382 bp from pter
77,221 bases
Minus strand

Genomic View for FAM169B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM169B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM169B Gene

Proteins for FAM169B Gene

  • Protein details for FAM169B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM169B
    Protein Accession:
    Secondary Accessions:
    • B5MDL8

    Protein attributes for FAM169B Gene

    192 amino acids
    Molecular mass:
    21411 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM169B Gene

Proteomics data for FAM169B Gene at MOPED

Post-translational modifications for FAM169B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM169B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM169B Gene

Domains for FAM169B Gene

Protein Domains for FAM169B Gene


Suggested Antigen Peptide Sequences for FAM169B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM169 family.
  • Belongs to the FAM169 family.
genes like me logo Genes that share domains with FAM169B: view

No data available for Gene Families for FAM169B Gene

Function for FAM169B Gene

Phenotypes for FAM169B Gene

genes like me logo Genes that share phenotypes with FAM169B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM169B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM169B Gene

Localization for FAM169B Gene

Subcellular locations from

Jensen Localization Image for FAM169B Gene COMPARTMENTS Subcellular localization image for FAM169B gene
Compartment Confidence
extracellular 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM169B Gene

Pathways for FAM169B Gene

SuperPathways for FAM169B Gene

No Data Available

Interacting Proteins for FAM169B Gene

Gene Ontology (GO) - Biological Process for FAM169B Gene


No data available for Pathways by source for FAM169B Gene

Transcripts for FAM169B Gene

mRNA/cDNA for FAM169B Gene

(1) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM169B Gene

Family with sequence similarity 169, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM169B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM169B Gene

No ASD Table

Relevant External Links for FAM169B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM169B Gene

mRNA expression in normal human tissues for FAM169B Gene

mRNA differential expression in normal tissues according to GTEx for FAM169B Gene

This gene is overexpressed in Liver (16.9) and Pancreas (7.2).

Protein differential expression in normal tissues for FAM169B Gene

This gene is overexpressed in Lung (38.7) and Peripheral blood mononuclear cells (24.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM169B Gene

SOURCE GeneReport for Unigene cluster for FAM169B Gene Hs.668070

genes like me logo Genes that share expressions with FAM169B: view

Expression partners for FAM169B Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM169B Gene

Orthologs for FAM169B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM169B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM169B 35
  • 97.92 (n)
  • 95.31 (a)
FAM169B 36
  • 95 (a)
(Mus musculus)
Mammalia Fam169b 16
(Bos Taurus)
Mammalia FAM169B 36
  • 35 (a)
(Canis familiaris)
Mammalia FAM169B 36
  • 24 (a)
(Monodelphis domestica)
Mammalia FAM169B 36
  • 26 (a)
(Gallus gallus)
Aves FAM169B 36
  • 26 (a)
(Anolis carolinensis)
Reptilia FAM169B 36
  • 40 (a)
(Danio rerio)
Actinopterygii fam169b 36
  • 20 (a)
Species with no ortholog for FAM169B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM169B Gene

Gene Tree for FAM169B (if available)
Gene Tree for FAM169B (if available)

Paralogs for FAM169B Gene

Paralogs for FAM169B Gene

(1) SIMAP similar genes for FAM169B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM169B: view

Variants for FAM169B Gene

Sequence variations from dbSNP and Humsavar for FAM169B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs881096 -- 98,513,428(-) CCAGG(A/G)ACAAT intron-variant
rs933809 -- 98,512,779(+) AGGTT(C/T)CAAGT intron-variant
rs933810 -- 98,512,938(+) GATGA(A/G)AGCCA intron-variant
rs1319864 -- 98,507,361(+) ATTTT(A/G)TATTC intron-variant
rs1319870 -- 98,505,142(+) AAAGA(C/T)GCTAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM169B Gene

Variant ID Type Subtype PubMed ID
nsv904539 CNV Loss 21882294
nsv1685 CNV Insertion 18451855
esv990309 CNV Deletion 20482838

Relevant External Links for FAM169B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM169B Gene

Disorders for FAM169B Gene

Relevant External Links for FAM169B

Genetic Association Database (GAD)

No disorders were found for FAM169B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM169B Gene

Publications for FAM169B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13. (PMID: 22354554) Thompson S.D. … Glass D.N. (Arthritis Rheum. 2012) 3 48
  3. Genome-wide population-based association study of extremely overweight young adults--the GOYA study. (PMID: 21935397) Paternoster L. … rensen T.I. (PLoS ONE 2011) 3
  4. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for FAM169B Gene

Sources for FAM169B Gene

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