FAM169B Gene
protein-coding GIFtS: 36
GCID: GC15M098980
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|
family with sequence similarity 169, member B
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Aliases
for FAM169B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 169, Member B1 2 | | KIAA0888L1 3 | | FLJ397431 | | Protein FAM169B2 |
Export aliases for FAM169B gene to outside databasesPrevious GC identifers: GC15M096797 GC15M075108 |
Summaries
for FAM169B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM169B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM169B gene promoter:
AML1a FOXD3 Tal-1beta NF-kappaB E47 GATA-1 Evi-1 FOXJ2 NF-kappaB1 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM169B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM169B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.3 Ensembl cytogenetic band: 15q26.3 HGNC cytogenetic band: 15q26.3FAM169B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M098980: view genomic region
(about GC identifiers)
Start:
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98,980,391 bp from pter |
End:
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99,057,611 bp from pter |
Size:
|
77,221 bases |
Orientation:
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minus strand |
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Proteins
for FAM169B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F169B_HUMAN, Q8N8A8 (See
protein sequence)Recommended Name: Protein FAM169B Size: 192 amino acids; 21411 Da
Secondary accessions: B5MDL8Explore the universe of human proteins at neXtProt for FAM169B: NX_Q8N8A8
FAM169B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_872368.2
ENSEMBL proteins: ENSP00000453554 ENSP00000332615
Human Recombinant Protein Products:
FAM169B Antibody Products:
Assay Products for FAM169B: |
Protein
Domains /
Families
for FAM169B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8N8A8 UniProtKB/Swiss-Prot: F169B_HUMAN, Q8N8A8Similarity: Belongs to the FAM169 family |
Function
for FAM169B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM169B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM169B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM169B (NM_182562) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM169B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM169B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM169B |
3 GenomeRNAi human phenotypes for FAM169B:
|
Pathways & Interactions
for FAM169B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM169B
|
Drugs & Compounds
for FAM169B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM169B
Search CenterWatch for drugs/clinical trials and news about FAM169B / F169B
|
Transcripts
for FAM169B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM169B gene: NM_182562.2 Unigene Cluster for FAM169B: Family with sequence similarity 169, member B Hs.668070 [show with all ESTs]Unigene Representative Sequence: AK0970622 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000558256(uc002buk.1) ENST00000332908
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM169B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM169B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM169B (NM_182562) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM169B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM169B |
Additional cDNA sequence: AK097062.1 1 DOTS entry: DT.75120813 3 AceView cDNA sequences: AI239516 AK097062 NM_182562
GeneLoc Exon Structure
|
Expression
for FAM169B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM169B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM169B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM169B
SOURCE GeneReport for Unigene cluster: Hs.668070
SABiosciences Custom PCR Arrays for FAM169B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM169B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM169B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM169B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM169B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM169B |
Orthologs
for FAM169B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM169B gene from 3/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM169B6 |
Uncharacterized protein |
27(a) |
1 ↔ 1 |
10(18615748-18661637) |
lizard
(Anolis carolinensis) |
Reptilia |
FAM169B6 |
-- |
43(a) |
1 ↔ 1 |
GL343363.1(1116855-1122983) |
zebrafish
(Danio rerio) |
Actinopterygii |
fam169b6 |
family with sequence similarity 169, member B |
21(a) |
1 ↔ 1 |
18(20840686-20845433) |
ENSEMBL Gene Tree for FAM169B (if available)
TreeFam Gene Tree for FAM169B (if available) |
Paralogs
for FAM169B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM169B gene
- FAM169A2
1 SIMAP similar gene for FAM169B using alignment to 1 protein entry: F169B_HUMAN:FAM169A
FAM169B for paralogs About GeneDecksing
|
Genomic Variants
for FAM169B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM169B (98980391 - 99057611 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM169B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM169B |
|
Disorders
/ Diseases
for FAM169B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM169B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM169B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM169B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genome-wide association analysis of juvenile idiopathi c arthritis identifies a new susceptibility locus at chromosomal region 3q13. (PubMed id 22354554)1 Thompson S.D....Glass D.N. (2012)
- Genome-wide population-based association study of extr emely overweight young adults--the GOYA study. (PubMed id 21935397)1 Paternoster L....Sorensen T.I. (2011)
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
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External Searches for FAM169B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM169B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM169B gene
(According to HUGE)
About This Section
| |
Specialized Databases showing FAM169B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM169B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM169B gene:
Search GeneIP for patents involving FAM169B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM169B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM169B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM169B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM169B | | | OriGene Protein Over-expression Lysate for FAM169B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM169B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM169B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM169B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM169B | | OriGene Custom Protein Services for FAM169B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM169B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM169B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM169B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM169B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM169B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM169B |
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| | | | Search Tocris compounds for FAM169B |
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 | | | FAM169B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM169B |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM169B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM169B |
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