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Aliases for FAM168A Gene

Aliases for FAM168A Gene

  • Family With Sequence Similarity 168, Member A 2 3
  • Tongue Cancer Chemotherapy Resistance-Associated Protein 1 2 3 4
  • KIAA0280 2 3 4
  • TCRP1 3 4
  • Protein FAM168A 3

External Ids for FAM168A Gene

Previous HGNC Symbols for FAM168A Gene

  • KIAA0280

Previous GeneCards Identifiers for FAM168A Gene

  • GC11U901028
  • GC11M072795
  • GC11M073117
  • GC11M069412
  • GC11M073111

Summaries for FAM168A Gene

GeneCards Summary for FAM168A Gene

FAM168A (Family With Sequence Similarity 168, Member A) is a Protein Coding gene. Diseases associated with FAM168A include tongue cancer. An important paralog of this gene is FAM168B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM168A Gene

Genomics for FAM168A Gene

Regulatory Elements for FAM168A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM168A Gene

73,400,478 bp from pter
73,598,189 bp from pter
197,712 bases
Minus strand

Genomic View for FAM168A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM168A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM168A Gene

Proteins for FAM168A Gene

  • Protein details for FAM168A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM168A
    Protein Accession:
    Secondary Accessions:
    • A2ICY2
    • A2ID81
    • Q86UG2

    Protein attributes for FAM168A Gene

    244 amino acids
    Molecular mass:
    26184 Da
    Quaternary structure:
    • May interact with FAM168B
    • Sequence=BAA13408.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM168A Gene


neXtProt entry for FAM168A Gene

Proteomics data for FAM168A Gene at MOPED

Post-translational modifications for FAM168A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM168A Gene

No data available for DME Specific Peptides for FAM168A Gene

Domains for FAM168A Gene

Protein Domains for FAM168A Gene


Suggested Antigen Peptide Sequences for FAM168A Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM168 family.
  • Belongs to the FAM168 family.
genes like me logo Genes that share domains with FAM168A: view

No data available for Gene Families for FAM168A Gene

Function for FAM168A Gene

Gene Ontology (GO) - Molecular Function for FAM168A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with FAM168A: view
genes like me logo Genes that share phenotypes with FAM168A: view

Animal Model Products

CRISPR Products

miRNA for FAM168A Gene

miRTarBase miRNAs that target FAM168A

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM168A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM168A Gene

Localization for FAM168A Gene

Subcellular locations from

Jensen Localization Image for FAM168A Gene COMPARTMENTS Subcellular localization image for FAM168A gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM168A Gene

Pathways for FAM168A Gene

SuperPathways for FAM168A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM168A Gene


No data available for Pathways by source for FAM168A Gene

Transcripts for FAM168A Gene

Unigene Clusters for FAM168A Gene

Family with sequence similarity 168, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM168A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM168A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1: -
SP2: - -

Relevant External Links for FAM168A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM168A Gene

mRNA expression in normal human tissues for FAM168A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for FAM168A Gene

This gene is overexpressed in Fetal Brain (24.9), Retina (16.8), Prostate (12.3), and Frontal cortex (6.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM168A Gene

SOURCE GeneReport for Unigene cluster for FAM168A Gene Hs.475334

genes like me logo Genes that share expressions with FAM168A: view

Expression partners for FAM168A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM168A Gene

Orthologs for FAM168A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM168A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM168A 35
  • 95.32 (n)
  • 99.57 (a)
FAM168A 36
  • 93 (a)
(Canis familiaris)
Mammalia FAM168A 35
  • 95.63 (n)
  • 99.59 (a)
FAM168A 36
  • 96 (a)
(Mus musculus)
Mammalia Fam168a 35
  • 94.89 (n)
  • 100 (a)
Fam168a 16
Fam168a 36
  • 100 (a)
(Pan troglodytes)
Mammalia FAM168A 35
  • 99.73 (n)
  • 100 (a)
FAM168A 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Fam168a 35
  • 94.95 (n)
  • 99.59 (a)
(Monodelphis domestica)
Mammalia FAM168A 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia FAM168A 36
  • 85 (a)
(Gallus gallus)
Aves FAM168A 35
  • 81.28 (n)
  • 94.89 (a)
FAM168A 36
  • 94 (a)
(Anolis carolinensis)
Reptilia FAM168A 36
  • 93 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam168a 35
  • 80.43 (n)
  • 91.49 (a)
Str.4204 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.13176 35
(Danio rerio)
Actinopterygii fam168a 35
  • 75.21 (n)
  • 83.76 (a)
wufc28c05 35
fam168a 36
  • 79 (a)
Species with no ortholog for FAM168A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM168A Gene

Gene Tree for FAM168A (if available)
Gene Tree for FAM168A (if available)

Paralogs for FAM168A Gene

Paralogs for FAM168A Gene

(1) SIMAP similar genes for FAM168A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM168A: view

Variants for FAM168A Gene

Sequence variations from dbSNP and Humsavar for FAM168A Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs478770 -- 73,489,724(-) agacc(A/C)gccca intron-variant
rs485339 -- 73,475,585(+) GGAAC(A/C)AAGTG intron-variant
rs487958 -- 73,486,163(+) ACTCA(A/C)AACAC intron-variant
rs490772 -- 73,506,140(-) GGTTT(G/T)GATAA intron-variant
rs492293 -- 73,472,159(+) ggacc(G/T)ctCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM168A Gene

Variant ID Type Subtype PubMed ID
esv2677115 CNV Deletion 23128226
nsv508641 CNV Loss 20534489
nsv520130 CNV Gain 19592680
nsv389 CNV Insertion 18451855
nsv38888 CNV Insertion 16902084
esv271125 CNV Insertion 20981092
esv22737 CNV Loss 19812545

Relevant External Links for FAM168A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM168A Gene

Disorders for FAM168A Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for FAM168A Gene in MalaCards »

(1) Disease for FAM168A Gene

(1) University of Copenhagen DISEASES for FAM168A Gene

genes like me logo Genes that share disorders with FAM168A: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for FAM168A Gene

Publications for FAM168A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T. … Nomura N. (DNA Res. 1996) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for FAM168A Gene

Sources for FAM168A Gene

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