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Aliases for FAM167B Gene

Aliases for FAM167B Gene

  • Family With Sequence Similarity 167, Member B 2 3
  • C1orf90 3 4
  • Chromosome 1 Open Reading Frame 90 2

External Ids for FAM167B Gene

Previous HGNC Symbols for FAM167B Gene

  • C1orf90

Previous GeneCards Identifiers for FAM167B Gene

  • GC01P032487
  • GC01P032712
  • GC01P030829

Summaries for FAM167B Gene

GeneCards Summary for FAM167B Gene

FAM167B (Family With Sequence Similarity 167, Member B) is a Protein Coding gene. An important paralog of this gene is FAM167A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM167B Gene

Genomics for FAM167B Gene

Regulatory Elements for FAM167B Gene

Genomic Location for FAM167B Gene

32,247,217 bp from pter
32,248,860 bp from pter
1,644 bases
Plus strand

Genomic View for FAM167B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM167B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM167B Gene

Proteins for FAM167B Gene

  • Protein details for FAM167B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM167B
    Protein Accession:
    Secondary Accessions:
    • Q5TDH6

    Protein attributes for FAM167B Gene

    163 amino acids
    Molecular mass:
    18414 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM167B Gene

Proteomics data for FAM167B Gene at MOPED

Post-translational modifications for FAM167B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM167B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM167B Gene

Domains & Families for FAM167B Gene

Protein Domains for FAM167B Gene


Suggested Antigen Peptide Sequences for FAM167B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM167 (SEC) family.
  • Belongs to the FAM167 (SEC) family.
genes like me logo Genes that share domains with FAM167B: view

No data available for Gene Families for FAM167B Gene

Function for FAM167B Gene

genes like me logo Genes that share phenotypes with FAM167B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM167B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM167B Gene

Localization for FAM167B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM167B Gene

Pathways & Interactions for FAM167B Gene

SuperPathways for FAM167B Gene

No Data Available

Interacting Proteins for FAM167B Gene

Gene Ontology (GO) - Biological Process for FAM167B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM167B Gene

Drugs & Compounds for FAM167B Gene

No Compound Related Data Available

Transcripts for FAM167B Gene

mRNA/cDNA for FAM167B Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM167B Gene

Family with sequence similarity 167, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM167B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM167B Gene

No ASD Table

Relevant External Links for FAM167B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM167B Gene

mRNA expression in normal human tissues for FAM167B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM167B Gene

This gene is overexpressed in Kidney - Cortex (x4.7).

SOURCE GeneReport for Unigene cluster for FAM167B Gene Hs.18449

genes like me logo Genes that share expression patterns with FAM167B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM167B Gene

Orthologs for FAM167B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM167B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM167B 35
  • 90.12 (n)
  • 90.12 (a)
FAM167B 36
  • 90 (a)
(Canis familiaris)
Mammalia FAM167B 35
  • 90.39 (n)
  • 90.8 (a)
FAM167B 36
  • 90 (a)
(Mus musculus)
Mammalia Fam167b 35
  • 84.16 (n)
  • 86.42 (a)
Fam167b 16
Fam167b 36
  • 85 (a)
(Pan troglodytes)
Mammalia FAM167B 35
  • 99.8 (n)
  • 100 (a)
FAM167B 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam167b 35
  • 87.04 (n)
  • 89.51 (a)
(Monodelphis domestica)
Mammalia FAM167B 36
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia FAM167B 36
  • 56 (a)
(Gallus gallus)
Aves FAM167B 35
  • 66.05 (n)
  • 54.94 (a)
FAM167B 36
  • 48 (a)
(Anolis carolinensis)
Reptilia FAM167B 36
  • 51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100497502 35
  • 55.62 (n)
  • 52.76 (a)
(Danio rerio)
Actinopterygii FAM167B 36
  • 45 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 17 (a)
CSA.10625 36
  • 31 (a)
Species with no ortholog for FAM167B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM167B Gene

Gene Tree for FAM167B (if available)
Gene Tree for FAM167B (if available)

Paralogs for FAM167B Gene

Paralogs for FAM167B Gene

(1) SIMAP similar genes for FAM167B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM167B: view

Variants for FAM167B Gene

Sequence variations from dbSNP and Humsavar for FAM167B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs669538 -- 32,245,759(+) GAAGG(C/T)ATATA upstream-variant-2KB
rs2291063 -- 32,247,598(-) TTGGC(C/T)TGGGC reference, synonymous-codon
rs3954186 -- 32,249,206(-) gtggc(C/T)gcctg downstream-variant-500B
rs11567839 -- 32,247,640(+) GGTTT(C/G/T)GACTC reference, missense, synonymous-codon
rs11567840 -- 32,247,709(+) GCTTT(G/T)CCCAG intron-variant

Variation tolerance for FAM167B Gene

Residual Variation Intolerance Score: 75.91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.63; 31.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM167B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM167B Gene

Disorders for FAM167B Gene

Relevant External Links for FAM167B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM167B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM167B Gene

Publications for FAM167B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 67
  3. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 67
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for FAM167B Gene

Sources for FAM167B Gene

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