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Aliases for FAM166B Gene

Aliases for FAM166B Gene

  • Family With Sequence Similarity 166 Member B 2 3 5
  • Family With Sequence Similarity 166, Member B 2

External Ids for FAM166B Gene

Summaries for FAM166B Gene

GeneCards Summary for FAM166B Gene

FAM166B (Family With Sequence Similarity 166 Member B) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM166B Gene

Genomics for FAM166B Gene

Regulatory Elements for FAM166B Gene

Enhancers for FAM166B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around FAM166B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM166B Gene

35,561,830 bp from pter
35,563,899 bp from pter
2,070 bases
Minus strand

Genomic View for FAM166B Gene

Genes around FAM166B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM166B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM166B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM166B Gene

Proteins for FAM166B Gene

  • Protein details for FAM166B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM166B
    Protein Accession:
    Secondary Accessions:
    • A1L3B2
    • B7ZBJ0

    Protein attributes for FAM166B Gene

    275 amino acids
    Molecular mass:
    30575 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM166B Gene


neXtProt entry for FAM166B Gene

Post-translational modifications for FAM166B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM166B Gene

No data available for DME Specific Peptides for FAM166B Gene

Domains & Families for FAM166B Gene

Protein Domains for FAM166B Gene


Suggested Antigen Peptide Sequences for FAM166B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0605 family.
  • Belongs to the UPF0605 family.
genes like me logo Genes that share domains with FAM166B: view

No data available for Gene Families for FAM166B Gene

Function for FAM166B Gene

Phenotypes for FAM166B Gene

genes like me logo Genes that share phenotypes with FAM166B: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM166B Gene

Localization for FAM166B Gene

Subcellular locations from

Jensen Localization Image for FAM166B Gene COMPARTMENTS Subcellular localization image for FAM166B gene
Compartment Confidence
mitochondrion 2
cytosol 1
extracellular 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM166B Gene

Pathways & Interactions for FAM166B Gene

SuperPathways for FAM166B Gene

No Data Available

Interacting Proteins for FAM166B Gene

Gene Ontology (GO) - Biological Process for FAM166B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM166B Gene

Drugs & Compounds for FAM166B Gene

No Compound Related Data Available

Transcripts for FAM166B Gene

mRNA/cDNA for FAM166B Gene

(5) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM166B Gene

Family with sequence similarity 166, member B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM166B Gene

No ASD Table

Relevant External Links for FAM166B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM166B Gene

mRNA expression in normal human tissues for FAM166B Gene

mRNA differential expression in normal tissues according to GTEx for FAM166B Gene

This gene is overexpressed in Adrenal Gland (x30.1) and Muscle - Skeletal (x13.0).

Protein differential expression in normal tissues from HIPED for FAM166B Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM166B Gene

Protein tissue co-expression partners for FAM166B Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM166B Gene:


SOURCE GeneReport for Unigene cluster for FAM166B Gene:

genes like me logo Genes that share expression patterns with FAM166B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM166B Gene

Orthologs for FAM166B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM166B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM166B 34
  • 84.86 (n)
  • 81.32 (a)
FAM166B 35
  • 80 (a)
(Canis familiaris)
Mammalia FAM166B 34
  • 84.61 (n)
  • 81.09 (a)
FAM166B 35
  • 69 (a)
(Mus musculus)
Mammalia Fam166b 34
  • 81.15 (n)
  • 74.59 (a)
Fam166b 16
Fam166b 35
  • 42 (a)
(Rattus norvegicus)
Mammalia Fam166b 34
  • 78.35 (n)
  • 74.68 (a)
(Monodelphis domestica)
Mammalia FAM166B 35
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia FAM166B 35
  • 48 (a)
(Pan troglodytes)
Mammalia FAM166B 35
  • 98 (a)
(Anolis carolinensis)
Reptilia FAM166B 35
  • 37 (a)
(Danio rerio)
Actinopterygii fam166b 35
  • 36 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG18335 35
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 27 (a)
-- 35
  • 25 (a)
Species where no ortholog for FAM166B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM166B Gene

Gene Tree for FAM166B (if available)
Gene Tree for FAM166B (if available)

Paralogs for FAM166B Gene

No data available for Paralogs for FAM166B Gene

Variants for FAM166B Gene

Sequence variations from dbSNP and Humsavar for FAM166B Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs755774 -- 35,562,552(-) CCCTG(C/T)GCCCG intron-variant, reference, synonymous-codon
rs117738302 -- 35,565,125(+) GACAC(C/T)ATCAC upstream-variant-2KB
rs139187940 -- 35,564,653(+) CTCTG(A/G)GCCGG upstream-variant-2KB
rs139298236 -- 35,565,824(+) CAAGC(A/G)TGGTG upstream-variant-2KB
rs139337875 -- 35,563,065(+) ACTGT(A/G)CCCGG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for FAM166B Gene

Variant ID Type Subtype PubMed ID
esv3620379 CNV gain 21293372
nsv1125318 OTHER inversion 24896259
nsv527028 CNV loss 19592680
nsv528256 CNV loss 19592680
nsv951701 CNV deletion 24416366

Variation tolerance for FAM166B Gene

Residual Variation Intolerance Score: 85.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.54; 77.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM166B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM166B Gene

Disorders for FAM166B Gene

Relevant External Links for FAM166B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM166B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM166B Gene

Publications for FAM166B Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3 65

Products for FAM166B Gene

Sources for FAM166B Gene

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