Aliases
for FAM166A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Family With Sequence Similarity 166, Member A1 2 | | Protein FAM166A2 |
| External Ids: | HGNC: 338181 | Entrez Gene: 4015652 | Ensembl: ENSG000001881637 | UniProtKB: Q6J2723 |
Export aliases for FAM166A gene to outside databasesPrevious GC identifers: GC09M139258 GC09M109597
|---|
Summaries
for FAM166A gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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GeneCards Summary for FAM166A Gene:
FAM166A (family with sequence similarity 166, member A) is a protein-coding gene.
|
Genomic Views
for FAM166A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | RefSeq DNA sequence:- NC_000009.12 NT_008470.20 NC_018920.2
Regulatory elements:
 Regulatory transcription factor binding sites in the FAM166A gene promoter:
SRF RFX1 GATA-3 p53 CP2 Pbx1a Pax-5 SRF (504 AA) XBP-1 C/EBPalpha
Other transcription factors
Search Chromatin IP Primers for FAM166A
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM166A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.3 Ensembl cytogenetic band: 9q34.3 HGNC cytogenetic band: 9q34.3FAM166A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M140138: view genomic region
(about GC identifiers)
Start:
|
140,138,036 bp from pter |
End:
|
140,142,222 bp from pter |
Size:
|
4,187 bases |
Orientation:
|
minus strand |
|
Proteins
for FAM166A gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
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UniProtKB/Swiss-Prot: F166A_HUMAN, Q6J272 (See
protein sequence)Recommended Name: Protein FAM166A Size: 317 amino acids; 36165 Da
Secondary accessions: A6NND9 Q8N830Alternative splicing: 2 isoforms: Q6J272-1 Q6J272-2 Explore the universe of human proteins at neXtProt for FAM166A: NX_Q6J272
Explore proteomics data for FAM166A at MOPED
See FAM166A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB
REFSEQ proteins: NP_001001710.1
ENSEMBL proteins: ENSP00000419151 ENSP00000344729 ENSP00000420741 ENSP00000373584
FAM166A Human Recombinant
Protein Products:FAM166A Antibody
Products:FAM166A Assay Products: |
Domains /
Families
for FAM166A gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | 1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q6J272 ProtoNet protein and cluster: Q6J272 UniProtKB/Swiss-Prot: F166A_HUMAN, Q6J272Similarity: Belongs to the UPF0605 family
FAM166A for domains About GeneDecksing
|
Function
for FAM166A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Phenotypes:
1 GenomeRNAi human phenotype for FAM166A:
Animal Models:
Inhib. RNA
Products: |  | OriGene RNAi products in human, mouse, rat for FAM166A
| | | Predesigned siRNA for gene silencing in human, mouse, rat FAM166A |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for FAM166A | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for FAM166A  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM166A |
Localization
for FAM166A gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Subcellular locations from COMPARTMENTS:
| Compartment | Confidence |
|---|
|
| cytosol | 2 | | nucleus | 2 | | extracellular | 1 | | mitochondrion | 1 |
|
Pathways & Interactions
for FAM166A gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
About This Section
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM166A
Interactions:
Search GeneGlobe Interaction Network for FAM166A
|
Drugs & Compounds
for FAM166A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
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 Browse compounds at ApexBio
 Browse Tocris compounds for FAM166A (F166A)
|
Transcripts
for FAM166A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
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REFSEQ mRNAs for FAM166A gene: NM_001001710.2 Unigene Cluster for FAM166A: Family with sequence similarity 166, member A Hs.522530 [show with all ESTs]Unigene Representative Sequence: AK0974194 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000471784 ENST00000344774(uc004cmi.1) ENST00000484720 ENST00000388932
Inhib. RNA
Products: | | OriGene RNAi products in human, mouse, rat for FAM166A
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat FAM166A |
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for FAM166A
| | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM166A | | | QuantiTect SYBR Green Assays in human, mouse, rat FAM166A | | | QuantiFast Probe-based Assays in human, mouse, rat FAM166A |
Additional mRNA sequence: AK097419.1 AY604177.1 BC132916.1 BC132918.1 14 DOTS entries: DT.95361033 DT.100059985 DT.100893018 DT.121210450 DT.100059989 DT.121210387 DT.87002174 DT.95360983 DT.121307030 DT.91779006 DT.91779055 DT.91994133 DT.92009164 DT.95361034 Selected AceView cDNA sequences (see all 86): NM_001001710 BF838536 AI001929 AY604177 T12649 BQ360314 BF838538 AK097419 CD621885 AI026681 AW242362 AA352446 CD621898 BE926604 BG938763 BX445177 CD621903 BX411826 BQ375830 BF870534 BE698093 BE940286 CD621878 BQ940167
GeneLoc Exon Structure
|
Expression
for FAM166A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
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FAM166A expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GATGTGGACA
About this image FAM166A Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  About this image
SOURCE GeneReport for Unigene cluster: Hs.522530
Custom PCR Arrays for FAM166A
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for FAM166A
| | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM166A | | | QuantiTect SYBR Green Assays in human, mouse, rat FAM166A | | | QuantiFast Probe-based Assays in human, mouse, rat FAM166A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM166A |
Orthologs
for FAM166A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for FAM166A gene from Selected species (see all 9) About this table
ENSEMBL Gene Tree for FAM166A (if available)
TreeFam Gene Tree for FAM166A (if available) |
Paralogs
for FAM166A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | Paralogs for FAM166A gene
FAM166A for paralogs About GeneDecksing
Selected Pseudogenes.org Pseudogenes for FAM166A (see all 15)
PGOHUM00000238663 PGOHUM00000239410 PGOHUM00000239737 PGOHUM00000234966 PGOHUM00000243875
|
Genomic Variants
for FAM166A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM166A (140138036 - 140142222 bp)
Structural Variations
Database of Genomic Variants (DGV) Selected variations for FAM166A (see all 27): About this table
Human Gene Mutation Database (HGMD): FAM166A
| | Site Specific Mutation Identification with PCR Assays |
| | SeqTarget long-range PCR primers for resequencing FAM166A |
|
Disorders
/ Diseases
for FAM166A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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FAM166A for disorders About GeneDecksing
Export disorders for FAM166A gene to outside databases
|
Publications
for FAM166A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
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PubMed articles for FAM166A gene integrated from 10 sources:
(articles sorted by number of sources associating them with FAM166A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (Nature 2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
|
External Searches for FAM166A gene (in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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|
Genome Databases showing FAM166A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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|
Other Databases showing FAM166A gene
(According to HUGE)
About This Section
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Specialized Databases showing FAM166A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for FAM166A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
TryGeneCards Plus | Patent Information for FAM166A gene:
Search GeneIP for patents involving FAM166A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM166A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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 | |
 |
| | | | |
 |
 |
|  | Block miRNA regulation of human, mouse, rat FAM166A using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing FAM166A | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM166A | | Predesigned siRNA for gene silencing in human, mouse, rat FAM166A | | | QuantiFast Probe-based Assays in human, mouse, rat FAM166A | | QuantiTect SYBR Green Assays in human, mouse, rat FAM166A | | | Custom PCR Arrays for FAM166A | | Search Chromatin IP Primers for FAM166A | | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM166A | | Search GeneGlobe Interaction Network for FAM166A | | | Regulatory tfbs in FAM166A promoter |
| |
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| | | |  |  |  |
 | | | | |
 |
 |
 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM166A |
| |  |  |  |  | | | Search ThermoFisher Antibodies for FAM166A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM166A |
| | | | LSBio Antibodies in human, mouse, rat for FAM166A |
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