Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM166A Gene

Aliases for FAM166A Gene

  • Family With Sequence Similarity 166 Member A 2 3 5
  • Family With Sequence Similarity 166, Member A 2 3
  • HSD46 3

External Ids for FAM166A Gene

Previous GeneCards Identifiers for FAM166A Gene

  • GC09M139258
  • GC09M140138
  • GC09M109597

Summaries for FAM166A Gene

GeneCards Summary for FAM166A Gene

FAM166A (Family With Sequence Similarity 166 Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM166A Gene

Genomics for FAM166A Gene

Regulatory Elements for FAM166A Gene

Genomic Location for FAM166A Gene

Chromosome:
9
Start:
137,243,583 bp from pter
End:
137,251,193 bp from pter
Size:
7,611 bases
Orientation:
Minus strand

Genomic View for FAM166A Gene

Genes around FAM166A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM166A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM166A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM166A Gene

Proteins for FAM166A Gene

  • Protein details for FAM166A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6J272-F166A_HUMAN
    Recommended name:
    Protein FAM166A
    Protein Accession:
    Q6J272
    Secondary Accessions:
    • A6NND9
    • Q8N830

    Protein attributes for FAM166A Gene

    Size:
    317 amino acids
    Molecular mass:
    36165 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM166A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM166A Gene

Proteomics data for FAM166A Gene at MOPED

Post-translational modifications for FAM166A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM166A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM166A Gene

Domains & Families for FAM166A Gene

Protein Domains for FAM166A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM166A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6J272

UniProtKB/Swiss-Prot:

F166A_HUMAN :
  • Belongs to the UPF0605 family.
Family:
  • Belongs to the UPF0605 family.
genes like me logo Genes that share domains with FAM166A: view

No data available for Gene Families for FAM166A Gene

Function for FAM166A Gene

genes like me logo Genes that share phenotypes with FAM166A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM166A Gene

Localization for FAM166A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM166A Gene COMPARTMENTS Subcellular localization image for FAM166A gene
Compartment Confidence
nucleus 5
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM166A Gene

Pathways & Interactions for FAM166A Gene

SuperPathways for FAM166A Gene

No Data Available

Interacting Proteins for FAM166A Gene

Gene Ontology (GO) - Biological Process for FAM166A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM166A Gene

Drugs & Compounds for FAM166A Gene

No Compound Related Data Available

Transcripts for FAM166A Gene

Unigene Clusters for FAM166A Gene

Family with sequence similarity 166, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM166A Gene

No ASD Table

Relevant External Links for FAM166A Gene

GeneLoc Exon Structure for
FAM166A
ECgene alternative splicing isoforms for
FAM166A

Expression for FAM166A Gene

mRNA expression in normal human tissues for FAM166A Gene

mRNA differential expression in normal tissues according to GTEx for FAM166A Gene

This gene is overexpressed in Testis (x39.3).

SOURCE GeneReport for Unigene cluster for FAM166A Gene Hs.522530

genes like me logo Genes that share expression patterns with FAM166A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM166A Gene

Orthologs for FAM166A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM166A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM166A 35
  • 98.21 (n)
  • 97.47 (a)
FAM166A 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM166A 36
  • 76 (a)
OneToOne
FAM166A 35
  • 82.49 (n)
  • 77.22 (a)
dog
(Canis familiaris)
Mammalia FAM166A 35
  • 83.49 (n)
  • 78.46 (a)
FAM166A 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam166a 16
Fam166a 36
  • 78 (a)
OneToOne
Fam166a 35
  • 80.79 (n)
  • 78.98 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM166A 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM166A 36
  • 48 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam166a 35
  • 80.49 (n)
  • 78.48 (a)
chicken
(Gallus gallus)
Aves FAM166A 35
  • 57.01 (n)
  • 46.13 (a)
FAM166A 36
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM166A 36
  • 49 (a)
OneToOne
Species with no ortholog for FAM166A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM166A Gene

ENSEMBL:
Gene Tree for FAM166A (if available)
TreeFam:
Gene Tree for FAM166A (if available)

Paralogs for FAM166A Gene

genes like me logo Genes that share paralogs with FAM166A: view

No data available for Paralogs for FAM166A Gene

Variants for FAM166A Gene

Sequence variations from dbSNP and Humsavar for FAM166A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs4073074 -- 137,244,732(-) GGCTA(C/T)GCTGG intron-variant, downstream-variant-500B, reference, synonymous-codon
rs9775264 -- 137,245,305(+) TGGCT(A/G)CCTGG splice-donor-variant
rs9695671 -- 137,246,970(+) CTGGC(A/G)TTTGC intron-variant
rs9697109 -- 137,248,112(+) TGGCT(C/T)GAGTC intron-variant, upstream-variant-2KB
rs9330201 -- 137,247,847(+) CACCT(C/T)GCTAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM166A Gene

Variant ID Type Subtype PubMed ID
nsv894387 CNV Gain 21882294
esv2422220 CNV Deletion 17116639
dgv8412n71 CNV Loss 21882294
dgv8416n71 CNV Loss 21882294
nsv524322 CNV Loss 19592680
dgv8423n71 CNV Loss 21882294
nsv894502 CNV Loss 21882294
nsv894506 CNV Gain 21882294
nsv894521 CNV Loss 21882294
dgv8437n71 CNV Gain 21882294
dgv8442n71 CNV Loss 21882294
dgv8445n71 CNV Loss 21882294
dgv8446n71 CNV Loss 21882294
dgv8447n71 CNV Loss 21882294
dgv8450n71 CNV Loss 21882294
nsv894603 CNV Gain+Loss 21882294
dgv8451n71 CNV Loss 21882294
dgv8452n71 CNV Gain+Loss 21882294
dgv8453n71 CNV Gain 21882294
dgv8454n71 CNV Gain 21882294
dgv8455n71 CNV Gain+Loss 21882294
nsv894631 CNV Loss 21882294
dgv8457n71 CNV Gain 21882294
nsv894637 CNV Loss 21882294
nsv894640 CNV Loss 21882294
nsv894641 CNV Loss 21882294
nsv894642 CNV Loss 21882294

Variation tolerance for FAM166A Gene

Residual Variation Intolerance Score: 82.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.82; 58.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM166A Gene

HapMap Linkage Disequilibrium report
FAM166A
Human Gene Mutation Database (HGMD)
FAM166A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM166A Gene

Disorders for FAM166A Gene

Relevant External Links for FAM166A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM166A

No disorders were found for FAM166A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM166A Gene

Publications for FAM166A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM166A Gene

Sources for FAM166A Gene

Back to Top

Content