FAM166A Gene
protein-coding GIFtS: 36
GCID: GC09M140138 (predicted)
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Family With Sequence Similarity 166, Member A
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Aliases
for FAM166A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
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| Aliases |
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| Family With Sequence Similarity 166, Member A1 2 | | Protein FAM166A2 |
Export aliases for FAM166A gene to outside databasesPrevious GC identifers: GC09M139258 GC09M109597 |
Summaries
for FAM166A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for FAM166A Gene: 
FAM166A (family with sequence similarity 166, member A) is a protein-coding gene.
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Genomic Views
for FAM166A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NT_024000.16 NC_018920.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM166A gene promoter:
SRF RFX1 GATA-3 p53 CP2 Pbx1a Pax-5 SRF (504 AA) XBP-1 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM166A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM166A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.3 Ensembl cytogenetic band: 9q34.3 HGNC cytogenetic band: 9q34.3FAM166A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M140138: view genomic region
(about GC identifiers)
Start:
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140,138,036 bp from pter |
End:
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140,142,222 bp from pter |
Size:
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4,187 bases |
Orientation:
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minus strand |
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Proteins
for FAM166A gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: F166A_HUMAN, Q6J272 (See
protein sequence)Recommended Name: Protein FAM166A Size: 317 amino acids; 36165 Da
Secondary accessions: A6NND9 Q8N830Alternative splicing: 2 isoforms: Q6J272-1 Q6J272-2 Explore the universe of human proteins at neXtProt for FAM166A: NX_Q6J272
Explore proteomics data for FAM166A at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q6J272
FAM166A Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins: NP_001001710.1
ENSEMBL proteins: ENSP00000419151 ENSP00000344729 ENSP00000420741 ENSP00000373584
Human Recombinant Protein Products for FAM166A:
FAM166A Antibody Products:
Assay Products for FAM166A: |
Protein
Domains /
Families
for FAM166A gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| 1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q6J272 ProtoNet protein and cluster: Q6J272 UniProtKB/Swiss-Prot: F166A_HUMAN, Q6J272Similarity: Belongs to the UPF0605 family
FAM166A for domains About GeneDecksing
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Function
for FAM166A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for FAM166A:
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for FAM166A | |  | Search LifeMap BioReagents cell lines for FAM166A | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM166A |
Pathways & Interactions
for FAM166A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM166A
|
Drugs & Compounds
for FAM166A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM166A (F166A)
Search CenterWatch for drugs/clinical trials and news about FAM166A / F166A
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Transcripts
for FAM166A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM166A gene: NM_001001710.1 Unigene Cluster for FAM166A: Family with sequence similarity 166, member A Hs.522530 [show with all ESTs]Unigene Representative Sequence: AK0974194 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000471784 ENST00000344774(uc004cmi.1) ENST00000484720 ENST00000388932
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for FAM166A
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM166A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM166A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM166A |
Additional mRNA sequence: AK097419.1 AY604177.1 BC132916.1 BC132918.1 14 DOTS entries: DT.95361033 DT.100059985 DT.100893018 DT.121210450 DT.100059989 DT.121210387 DT.87002174 DT.95360983 DT.121307030 DT.91779006 DT.91779055 DT.91994133 DT.92009164 DT.95361034 24/86 AceView cDNA sequences (see all 86): AY604177 AI001929 NM_001001710 AK097419 BF838538 BF838536 T12649 BQ360314 BE698093 CD621898 BE926604 BX411826 BQ940167 BF870534 AW242362 BE940286 BX445177 AI026681 AA352446 CD621878 BX406886 BQ375830 CD621885 BG938763
GeneLoc Exon Structure
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Expression
for FAM166A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM166A expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GATGTGGACA
About this image
See FAM166A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM166A
SOURCE GeneReport for Unigene cluster: Hs.522530
SABiosciences Custom PCR Arrays for FAM166A
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for FAM166A
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM166A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM166A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM166A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM166A |
Orthologs
for FAM166A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for FAM166A gene from 5/12 species (see all 12) About this table
ENSEMBL Gene Tree for FAM166A (if available)
TreeFam Gene Tree for FAM166A (if available) |
Paralogs
for FAM166A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM166A gene
FAM166A for paralogs About GeneDecksing
5/15 Pseudogenes.org Pseudogenes for FAM166A (see all 15)
PGOHUM00000238663 PGOHUM00000239410 PGOHUM00000239737 PGOHUM00000234966 PGOHUM00000243875
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Genomic Variants
for FAM166A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FAM166A (140138036 - 140142222 bp)
Structural Variations
Database of Genomic Variants (DGV) 10/27 variations for FAM166A (see all 27): About this table
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM166A |
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Disorders
/ Diseases
for FAM166A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM166A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM166A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM166A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM166A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM166A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM166A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM166A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM166A | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM166A gene:
Search GeneIP for patents involving FAM166A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM166A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM166A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM166A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM166A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM166A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM166A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM166A |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM166A |
|  |  |  |  | | | | Search ThermoFisher Antibodies for FAM166A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM166A |
| |  |  |  | | | | LSBio Antibodies in human, mouse, rat for FAM166A |
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