Aliases for FAM166A Gene
Aliases for FAM166A Gene
External Ids for FAM166A Gene
- HGNC: 33818
- Entrez Gene: 401565
- Ensembl: ENSG00000188163
- UniProtKB: Q6J272
Previous GeneCards Identifiers for FAM166A Gene
- GC09M139258
- GC09M140138
- GC09M109597
Summaries for FAM166A Gene
GeneCards Summary for FAM166A Gene
FAM166A (Family With Sequence Similarity 166 Member A) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM166A Gene
Genomics for FAM166A Gene
Regulatory Elements for FAM166A Gene
Enhancers for FAM166A Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH09G136514 | 1.3 | Ensembl ENCODE dbSUPER | 5.7 | +732.7 | 732737 | 7.2 | BCOR TFAP4 SAP130 ARID4B MAX ZMYM3 ZIC2 RAD21 BCL11B RARA | SNAPC4 NALT1 FAM166A SEC16A SLC34A3 MIR4673 |
| GH09G137386 | 1.2 | Ensembl ENCODE dbSUPER | 4.9 | -136.8 | -136801 | 2.7 | TFAP4 SAP130 NR2F1 ZFHX2 NCOR1 ZBTB48 EGR1 POLR2A PATZ1 KLF9 | LOC101928932 FAM166A EXD3 GC09M137332 |
| GH09G137417 | 1.2 | FANTOM5 Ensembl dbSUPER | 3.1 | -166.5 | -166509 | 1.0 | MXI1 USF1 BHLHE40 MAX USF2 GATAD2B POLR2A KDM6A MYC RBFOX2 | FAM166A STPG3 ABCA2 LCNL1 EXD3 GC09M137332 |
| GH09G137369 | 0.5 | ENCODE | 5.8 | -119.4 | -119449 | 1.3 | POLR2A SMARCA4 SCRT2 EZH2 | FAM166A GC09M137332 EXD3 |
| GH09G137569 | 0.5 | FANTOM5 | 3.7 | -318.2 | -318187 | 0.4 | ZFHX2 ZNF366 ZNF670 EGR2 | EHMT1 FAM166A STPG3 DPH7 MRPL41 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM166A on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM166A gene promoter:
Regulatory Element Products
Genomic Location for FAM166A Gene
- Chromosome:
- 9
- Start:
- 137,243,583 bp from pter
- End:
- 137,251,193 bp from pter
- Size:
- 7,611 bases
- Orientation:
- Minus strand
Genomic View for FAM166A Gene
Genes around FAM166A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q34.3 by Ensembl
- 9q34.3 by Entrez Gene
- 9q34.3 by HGNC
FAM166A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM166A Gene
Proteins for FAM166A Gene
-
Protein details for FAM166A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6J272-F166A_HUMAN
- Recommended name:
- Protein FAM166A
- Protein Accession:
- Q6J272
- A6NND9
- Q8N830
Protein attributes for FAM166A Gene
- Size:
- 317 amino acids
- Molecular mass:
- 36165 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for FAM166A Gene
Other Protein References for FAM166A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM166A
-
Abcam antibodies for FAM166A
- Invitrogen Antibodies for FAM166A
- Search GeneTex for Antibodies for FAM166A
Protein Products
-
OriGene Purified Proteins for FAM166A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM166A
- Origene Custom Protein Services for FAM166A
- Search GeneTex for Proteins for FAM166A
No data available for DME Specific Peptides for FAM166A Gene
Domains & Families for FAM166A Gene
Protein Domains for FAM166A Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM166A Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6J272- Family:
-
- Belongs to the UPF0605 family.
No data available for Gene Families for FAM166A Gene
Function for FAM166A Gene
Phenotypes for FAM166A Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM166A
-
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM166A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM166A gene
- Search ViGene Biosciences for FAM166A
CRISPR Products
-
OriGene CRISPR knockouts for FAM166A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM166A
- GenScript: Design CRISPR guide RNA sequences for FAM166A
miRNA Products
- Search ViGene Biosciences for FAM166A
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM166A
- Browse OriGene Inhibitory RNA Products For FAM166A
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM166A gene
Clone Products
-
OriGene ORF clones in human for FAM166A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM166A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM166A
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for FAM166A
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM166A gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM166A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM166A gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM166A Gene
Localization for FAM166A Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 21630459 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM166A Gene
Transcripts for FAM166A Gene
mRNA/cDNA for FAM166A Gene
- (7) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (86) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM166A Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM166A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM166A
- GenScript: Design CRISPR guide RNA sequences for FAM166A
miRNA Products
- Search ViGene Biosciences for FAM166A
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM166A
- Browse OriGene Inhibitory RNA Products For FAM166A
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM166A gene
Clone Products
-
OriGene ORF clones in human for FAM166A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM166A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM166A
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for FAM166A Gene
mRNA differential expression in normal tissues according to GTEx for FAM166A Gene
This gene is overexpressed in Testis (x39.3).
NURSA nuclear receptor signaling pathways regulating expression of FAM166A Gene:
FAM166ASOURCE GeneReport for Unigene cluster for FAM166A Gene:
Hs.522530Evidence on tissue expression from TISSUES for FAM166A Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for FAM166A
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM166A Gene
Orthologs for FAM166A Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM166A 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM166A 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM166A 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam166a 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam166a 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAM166A 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM166A 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FAM166A 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FAM166A 35 |
|
OneToOne |
- Species where no ortholog for FAM166A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM166A Gene
Pseudogenes.org Pseudogenes for FAM166A Gene
No data available for Paralogs for FAM166A Gene
Variants for FAM166A Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000357207 | -- | 137,250,582(+) | GCTCC(A/G)GAGAC | nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1000801398 | -- | 137,249,230(+) | CATAC(A/G)TGCTG | intron-variant, upstream-variant-2KB | |
| rs1001148781 | -- | 137,249,393(+) | GAAGC(C/T)GTCTG | intron-variant, upstream-variant-2KB | |
| rs1001153927 | -- | 137,243,959(+) | CTTGG(C/G)GCTCG | intron-variant, downstream-variant-500B | |
| rs1001431152 | -- | 137,247,210(+) | AACCT(C/G)GGAGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv13009n54 | CNV | loss | 21841781 |
| dgv13011n54 | CNV | loss | 21841781 |
| esv2422220 | CNV | deletion | 17116639 |
| nsv1161918 | CNV | duplication | 26073780 |
| nsv524322 | CNV | loss | 19592680 |
| nsv951207 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
82.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.82;
58.51% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM166A Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM166A Gene
Disorders for FAM166A Gene
Relevant External Links for FAM166A
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM166A
No disorders were found for FAM166A Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM166A Gene
Publications for FAM166A Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3 64
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for FAM166A Gene
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- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Assay Services
- OriGene Purified Proteins for FAM166A
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM166A
- Browse OriGene Inhibitory RNA Products For FAM166A
- OriGene qPCR primer pairs for FAM166A
- OriGene CRISPR knockouts for FAM166A
- OriGene ORF clones in human for FAM166A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for FAM166A in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM166A
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- GenScript: Design CRISPR guide RNA sequences for FAM166A
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- CloneReady with Over 120,000 Genes
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- Novus Biologicals Antibodies for FAM166A
- Novus Biologicals proteins and lysates for FAM166A
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for FAM166A
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for FAM166A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Search GeneTex for Antibodies for FAM166A
- Search GeneTex for Proteins for FAM166A
- ViGene Biosciences adenoviral particle packaged cDNA for FAM166A gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM166A gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM166A gene
- Search ViGene Biosciences for FAM166A
- Horizon Cell Lines for FAM166A
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM166A
- VectorBuilder custom plasmid, inducible vectors for FAM166A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM166A
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM166A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer