Aliases for FAM163B Gene
Aliases for FAM163B Gene
External Ids for FAM163B Gene
- HGNC: 33277
- Entrez Gene: 642968
- Ensembl: ENSG00000196990
- UniProtKB: P0C2L3
Previous HGNC Symbols for FAM163B Gene
- C9orf166
Previous GeneCards Identifiers for FAM163B Gene
- GC09M135436
- GC09M136444
- GC09M105944
Summaries for FAM163B Gene
GeneCards Summary for FAM163B Gene
FAM163B (Family With Sequence Similarity 163 Member B) is a Protein Coding gene. An important paralog of this gene is FAM163A.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM163B Gene
Genomics for FAM163B Gene
Regulatory Elements for FAM163B Gene
Enhancers for FAM163B Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH09G133508 | 1.4 | Ensembl ENCODE dbSUPER | 10.8 | +100.4 | 100351 | 1.4 | FOXA2 SIN3A KLF17 FEZF1 YY1 GLIS2 ZSCAN5C EGR2 ZBTB11 ZNF843 | FAM163B CACFD1 LOC102723855 MYMK |
| GH09G133505 | 1.3 | Ensembl ENCODE | 10.8 | +103.5 | 103456 | 2.0 | FOXA2 AGO1 ARID4B SIN3A DMAP1 YY1 ZNF766 FOS ZNF263 SP5 | ADAMTSL2 MYMK WDR5 REXO4 FAM163B GTF3C4 LOC102723855 |
| GH09G133557 | 1.1 | Ensembl ENCODE | 11.7 | +51.3 | 51291 | 2.5 | INSM2 SIN3A KLF17 GATA2 EGR1 FOS JUNB HDAC8 MEF2D ZFP69B | ENSG00000273249 TSC1 ADAMTSL2 MYMK FAM163B DBH |
| GH09G133676 | 1 | FANTOM5 ENCODE | 10.9 | -67.4 | -67431 | 1.9 | CTCF SREBF2 NR2F2 HIC1 GLIS2 POLR2A IKZF1 GLIS1 SCRT2 ZBTB33 | DBH FAM163B DBH-AS1 RPL7A GC09P133683 LOC105376308 |
| GH09G133507 | 1 | ENCODE | 10.8 | +102.1 | 102052 | 0.1 | ATF1 CREB3L1 AGO1 ZFP64 SIN3A ARID4B DMAP1 ZNF121 ZNF263 SP5 | FAM163B LOC102723855 MYMK |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM163B on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM163B gene promoter:
Regulatory Element Products
Genomic Location for FAM163B Gene
- Chromosome:
- 9
- Start:
- 133,577,076 bp from pter
- End:
- 133,609,920 bp from pter
- Size:
- 32,845 bases
- Orientation:
- Minus strand
Genomic View for FAM163B Gene
Genes around FAM163B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q34.2 by Ensembl
- 9q34.2 by Entrez Gene
- 9q34.2 by HGNC
FAM163B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM163B Gene
Proteins for FAM163B Gene
-
Protein details for FAM163B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P0C2L3-F163B_HUMAN
- Recommended name:
- Protein FAM163B
- Protein Accession:
- P0C2L3
- B2RUZ5
Protein attributes for FAM163B Gene
- Size:
- 166 amino acids
- Molecular mass:
- 18190 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM163B Gene
Post-translational modifications for FAM163B Gene
Other Protein References for FAM163B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM163B
- Invitrogen Antibodies for FAM163B
- Search GeneTex for Antibodies for FAM163B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAM163B
- Origene Custom Protein Services for FAM163B
- Novus Biologicals proteins for FAM163B
- Search GeneTex for Proteins for FAM163B
Assay Products
No data available for DME Specific Peptides for FAM163B Gene
Domains & Families for FAM163B Gene
Suggested Antigen Peptide Sequences for FAM163B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P0C2L3- Family:
-
- Belongs to the FAM163 family.
No data available for Gene Families for FAM163B Gene
Function for FAM163B Gene
Phenotypes for FAM163B Gene
- GenomeRNAi human phenotypes for FAM163B:
Animal Model Products
-
Taconic Biosciences Mouse Models for FAM163B
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM163B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
- Search ViGene Biosciences for FAM163B
CRISPR Products
-
OriGene CRISPR knockouts for FAM163B
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM163B
- GenScript: Design CRISPR guide RNA sequences for FAM163B
miRNA for FAM163B Gene
- miRTarBase miRNAs that target FAM163B
miRNA Products
- Search ViGene Biosciences for FAM163B
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for FAM163B
- Browse OriGene Inhibitory RNA Products For FAM163B
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
Clone Products
-
OriGene ORF clones in human for FAM163B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM163B
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM163B gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM163B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM163B Gene
Localization for FAM163B Gene
Subcellular locations from UniProtKB/Swiss-Prot for FAM163B Gene
- Membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 1 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016021 | integral component of membrane | IEA | -- |
Transcripts for FAM163B Gene
mRNA/cDNA for FAM163B Gene
- (8) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM163B Gene
- Family with sequence similarity 163, member B:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for FAM163B
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM163B
- GenScript: Design CRISPR guide RNA sequences for FAM163B
miRNA Products
- Search ViGene Biosciences for FAM163B
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for FAM163B
- Browse OriGene Inhibitory RNA Products For FAM163B
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
Clone Products
-
OriGene ORF clones in human for FAM163B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM163B Gene
mRNA differential expression in normal tissues according to GTEx for FAM163B Gene
This gene is overexpressed in Brain - Cortex (x13.0), Brain - Frontal Cortex (BA9) (x10.5), Brain - Anterior cingulate cortex (BA24) (x9.5), and Brain - Amygdala (x4.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM163B Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FAM163B Gene:
FAM163BSOURCE GeneReport for Unigene cluster for FAM163B Gene:
Hs.741379Primer Products
-
OriGene qPCR primer pairs for FAM163B
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM163B Gene
Orthologs for FAM163B Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM163B 34 |
|
||
| -- 35 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | FAM163B 34 |
|
||
| -- 35 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | FAM163B 34 |
|
||
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Fam163b 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam163b 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | LOC100858326 34 |
|
||
| -- 35 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam163b 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100537920 34 |
|
||
| fam163b 35 |
|
OneToMany |
- Species where no ortholog for FAM163B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM163B Gene
(1) SIMAP similar genes for FAM163B Gene using alignment to 1 proteins:
Variants for FAM163B Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000044843 | -- | 133,596,122(+) | GAGGT(A/G)GTGGG | intron-variant | |
| rs1000143439 | -- | 133,583,399(+) | GGCTA(A/C)ACCCC | intron-variant, upstream-variant-2KB | |
| rs1000208791 | -- | 133,602,608(+) | TTTTT(G/T)TTTTT | intron-variant, upstream-variant-2KB | |
| rs1000212374 | -- | 133,582,037(+) | ATCAT(C/G)TGTGT | intron-variant, upstream-variant-2KB | |
| rs1000315124 | -- | 133,603,156(+) | CGCCA(A/G)CTGGA | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4157n106 | CNV | deletion | 24896259 |
| esv2656927 | CNV | deletion | 23128226 |
| esv2739138 | CNV | deletion | 23290073 |
| esv2759719 | CNV | gain+loss | 17122850 |
| nsv1075278 | CNV | deletion | 25765185 |
| nsv1125319 | OTHER | inversion | 24896259 |
| nsv428225 | CNV | loss | 18775914 |
| nsv951799 | CNV | deletion | 24416366 |
Gene Damage Index Score:
0.68;
14.44% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM163B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM163B
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM163B Gene
Disorders for FAM163B Gene
Relevant External Links for FAM163B
No disorders were found for FAM163B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM163B Gene
Publications for FAM163B Gene
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
- Genome-wide meta-analyses identify multiple loci associated with smoking behavior. (PMID: 20418890) (Nat. Genet. 2010) 46 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 64
Products for FAM163B Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
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- Browse Cell Selection and Detection Kits
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- Custom Antibody Services
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- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAM163B
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM163B
- Browse OriGene Inhibitory RNA Products For FAM163B
- OriGene qPCR primer pairs for FAM163B
- OriGene CRISPR knockouts for FAM163B
- OriGene ORF clones in human for FAM163B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for FAM163B in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM163B
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- GenScript Custom overexpressing Cell Line Services for FAM163B
- GenScript: Design CRISPR guide RNA sequences for FAM163B
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM163B
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FAM163B
- Novus Biologicals proteins for FAM163B
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for FAM163B
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- ViGene Biosciences adenoviral particle packaged cDNA for FAM163B gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM163B gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
- Search ViGene Biosciences for FAM163B
- Horizon Cell Lines for FAM163B
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM163B
- VectorBuilder custom plasmid, inducible vectors for FAM163B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM163B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM163B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer