Aliases for FAM163B Gene
Aliases for FAM163B Gene
External Ids for FAM163B Gene
- HGNC: 33277
- Entrez Gene: 642968
- Ensembl: ENSG00000196990
- UniProtKB: P0C2L3
Previous HGNC Symbols for FAM163B Gene
- C9orf166
Previous GeneCards Identifiers for FAM163B Gene
- GC09M135436
- GC09M136444
- GC09M105944
Summaries for FAM163B Gene
GeneCards Summary for FAM163B Gene
FAM163B (Family With Sequence Similarity 163 Member B) is a Protein Coding gene. An important paralog of this gene is FAM163A.
Additional gene information for FAM163B Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM163B Gene
Genomics for FAM163B Gene
GeneHancer (GH) Regulatory Elements for FAM163B Gene
Promoters and enhancers for FAM163B Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH09I133609 | Enhancer | 0.4 | FANTOM5 | 552.2 | -0.2 | -162 | 0.4 | REST EZH2 | FAM163B DBH DBH-AS1 ADAMTSL2 ENSG00000261018 | |
GH09I133505 | Enhancer | 1.2 | Ensembl ENCODE | 10.9 | +103.5 | 103456 | 2 | FOXA2 ARID4B DMAP1 ZNF48 YY1 TCF12 ZNF766 FOS RXRA NCOA1 | ADAMTSL2 MYMK FAM163B LOC102723855 | |
GH09I133508 | Enhancer | 1.2 | Ensembl ENCODE dbSUPER | 10.9 | +100.4 | 100351 | 1.4 | CLOCK FOXA2 KLF17 MZF1 SIN3A FEZF1 YY1 ZNF335 GLIS2 ZSCAN5C | FAM163B CACFD1 LOC102723855 MYMK | |
GH09I133557 | Enhancer | 1 | Ensembl ENCODE | 11.7 | +51.3 | 51290 | 2.5 | INSM2 KLF17 SIN3A EGR1 FOS IKZF2 RUNX3 HDAC8 ZFP69B MEF2D | ENSG00000273249 TSC1 ADAMTSL2 MYMK FAM163B DBH GTF3C5 BRD3 DDX31 | |
GH09I133676 | Enhancer | 0.7 | FANTOM5 ENCODE | 10.9 | -67.4 | -67431 | 1.9 | RXRA IKZF1 NR2F2 | DBH FAM163B DBH-AS1 RPL7A GC09P133683 LOC105376308 SARDH |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around FAM163B on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for FAM163B Gene
Genomic Locations for FAM163B Gene
- chr9:133,577,076-133,609,920
- (GRCh38/hg38)
- Size:
- 32,845 bases
- Orientation:
- Minus strand
- chr9:136,443,537-136,451,319
- (GRCh37/hg19)
Genomic View for FAM163B Gene
Genes around FAM163B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q34.2 by Ensembl
- 9q34.2 by Entrez Gene
- 9q34.2 by HGNC
FAM163B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)


RefSeq DNA sequence for FAM163B Gene
Proteins for FAM163B Gene
-
Protein details for FAM163B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P0C2L3-F163B_HUMAN
- Recommended name:
- Protein FAM163B
- Protein Accession:
- P0C2L3
- B2RUZ5
Protein attributes for FAM163B Gene
- Size:
- 166 amino acids
- Molecular mass:
- 18190 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM163B Gene
Post-translational modifications for FAM163B Gene
No Post-translational modifications
Other Protein References for FAM163B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM163B
- Invitrogen Antibodies for FAM163B
- Search GeneTex for Antibodies for FAM163B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAM163B
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- Novus Biologicals proteins for FAM163B
- Search GeneTex for Proteins for FAM163B
Assay Products
No data available for DME Specific Peptides for FAM163B Gene
Domains & Families for FAM163B Gene
Gene Families for FAM163B Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for FAM163B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P0C2L3- Family:
-
- Belongs to the FAM163 family.
Function for FAM163B Gene
Phenotypes From GWAS Catalog for FAM163B Gene
Phenotypes for FAM163B Gene
- GenomeRNAi human phenotypes for FAM163B:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM163B
-
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM163B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
- Search ViGene Biosciences for FAM163B
CRISPR Products
-
OriGene CRISPR knockouts for FAM163B
- genomics-online: gRNA clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
- Applied Biological Materials CRISPR for FAM163B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM163B
- GenScript: Design CRISPR guide RNA sequences for FAM163B
miRNA for FAM163B Gene
- miRTarBase miRNAs that target FAM163B
miRNA Products
- Search ViGene Biosciences for FAM163B
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FAM163B
- Browse OriGene Inhibitory RNA Products For FAM163B
- genomics-online: shRNA clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM163B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM163B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for FAM163B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for FAM163B
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM163B gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM163B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM163B Gene
Localization for FAM163B Gene
Subcellular locations from UniProtKB/Swiss-Prot for FAM163B Gene
- Membrane; Single-pass membrane protein.
- Cytosol (2)
- Nuclear bodies (2)
- Plasma membrane (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016021 | integral component of membrane | IEA | -- |
Transcripts for FAM163B Gene
mRNA/cDNA for FAM163B Gene
- (8) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM163B Gene
- Family with sequence similarity 163, member B:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for FAM163B
- genomics-online: gRNA clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
- Applied Biological Materials CRISPR for FAM163B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM163B
- GenScript: Design CRISPR guide RNA sequences for FAM163B
miRNA Products
- Search ViGene Biosciences for FAM163B
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FAM163B
- Browse OriGene Inhibitory RNA Products For FAM163B
- genomics-online: shRNA clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM163B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM163B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for FAM163B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for FAM163B Gene
mRNA differential expression in normal tissues according to GTEx for FAM163B Gene
This gene is overexpressed in Brain - Cortex (x13.0), Brain - Frontal Cortex (BA9) (x10.5), Brain - Anterior cingulate cortex (BA24) (x9.5), and Brain - Amygdala (x4.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM163B Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FAM163B Gene:
FAM163BSOURCE GeneReport for Unigene cluster for FAM163B Gene:
Hs.741379Primer Products
-
OriGene qPCR primer pairs for FAM163B
- genomics-online: primer clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM163B Gene
Orthologs for FAM163B Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | FAM163B 33 |
|
||
-- 34 |
|
OneToMany | |||
dog (Canis familiaris) |
Mammalia | FAM163B 33 |
|
||
-- 34 |
|
OneToMany | |||
cow (Bos Taurus) |
Mammalia | FAM163B 33 |
|
||
-- 34 |
|
OneToMany | |||
mouse (Mus musculus) |
Mammalia | Fam163b 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Fam163b 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
chicken (Gallus gallus) |
Aves | LOC100858326 33 |
|
||
-- 34 |
|
OneToMany | |||
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | fam163b 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | LOC100537920 33 |
|
||
fam163b 34 |
|
OneToMany |
- Species where no ortholog for FAM163B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM163B Gene
(1) SIMAP similar genes for FAM163B Gene using alignment to 1 proteins:
Variants for FAM163B Gene
SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000044843 | -- | 133,596,122(-) | G/A | genic_upstream_transcript_variant, intron_variant | |
rs1000143439 | -- | 133,583,399(-) | A/C | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000208791 | -- | 133,602,608(-) | T/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000212374 | -- | 133,582,037(-) | C/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000315124 | -- | 133,603,156(-) | A/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv4157n106 | CNV | deletion | 24896259 |
esv2656927 | CNV | deletion | 23128226 |
esv2739138 | CNV | deletion | 23290073 |
esv2759719 | CNV | gain+loss | 17122850 |
nsv1075278 | CNV | deletion | 25765185 |
nsv1125319 | OTHER | inversion | 24896259 |
nsv428225 | CNV | loss | 18775914 |
nsv951799 | CNV | deletion | 24416366 |
Gene Damage Index Score:
0.68;
14.44% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FAM163B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM163B
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM163B Gene
Disorders for FAM163B Gene
Additional Disease Information for FAM163B
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for FAM163B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM163B Gene
Publications for FAM163B Gene
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58
- Genome-wide meta-analyses identify multiple loci associated with smoking behavior. (PMID: 20418890) Tobacco and Genetics Consortium (Nature genetics 2010) 44 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E … Simpson AJ (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 58
Products for FAM163B Gene
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- Novus Biologicals Antibodies for FAM163B
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- Invitrogen Antibodies for FAM163B
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM163B
- VectorBuilder custom plasmid, inducible vectors for FAM163B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM163B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for FAM163B
- Search GeneTex for Proteins for FAM163B
- ViGene Biosciences adenoviral particle packaged cDNA for FAM163B gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM163B gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM163B gene
- Search ViGene Biosciences for FAM163B
- Horizon Cell Lines for FAM163B
- genomics-online: cdna clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
- orf clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
- genomics-online: gRNA clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
- genomics-online: primer clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
- genomics-online: shRNA clones - Search results for 74 available FAM163B gene related products
- Overview of 74 available FAM163B gene related products
Sources for FAM163B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew