FAM163B Gene
protein-coding GIFtS: 33
GCID: GC09M136444
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Family With Sequence Similarity 163, Member B(Previous name: chromosome 9 open reading frame 166)
(Previous symbol: C9orf166)
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Aliases
for FAM163B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 163, Member B1 2 | | C9orf1661 2 3 | | Chromosome 9 Open Reading Frame 1661 | | Protein FAM163B2 |
Export aliases for FAM163B gene to outside databasesPrevious GC identifers: GC09M135436 GC09M105944 |
Summaries
for FAM163B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for FAM163B Gene: 
FAM163B (family with sequence similarity 163, member B) is a protein-coding gene. An important paralog of this gene is LOC100996390.
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Genomic Views
for FAM163B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NT_035014.4 NC_018920.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM163B gene promoter:
Tal-1 MyoD Tal-1beta AP-2gamma E47 Arnt AP-2beta AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM163B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM163B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.2 Ensembl cytogenetic band: 9q34.2 HGNC cytogenetic band: 9q34.2FAM163B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M136444: view genomic region
(about GC identifiers)
Start:
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136,443,537 bp from pter |
End:
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136,451,319 bp from pter |
Size:
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7,783 bases |
Orientation:
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minus strand |
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Proteins
for FAM163B gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: F163B_HUMAN, P0C2L3 (See
protein sequence)Recommended Name: Protein FAM163B Size: 166 amino acids; 18190 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: B2RUZ5Explore the universe of human proteins at neXtProt for FAM163B: NX_P0C2L3
Explore proteomics data for FAM163B at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_P0C2L3
FAM163B Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins: NP_001073984.1
ENSEMBL proteins: ENSP00000419867 ENSP00000349336
Human Recombinant Protein Products for FAM163B:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0016021 | integral to membrane |
IEA | -- |
FAM163B for ontologies About GeneDecksing
FAM163B Antibody Products:
Assay Products for FAM163B: |
Protein
Domains /
Families
for FAM163B gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: P0C2L3 UniProtKB/Swiss-Prot: F163B_HUMAN, P0C2L3Similarity: Belongs to the FAM163 family |
Function
for FAM163B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
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Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM163B |
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Pathways & Interactions
for FAM163B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM163B
|
Drugs & Compounds
for FAM163B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
IUPHAR,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM163B (F163B)
Search CenterWatch for drugs/clinical trials and news about FAM163B / F163B
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Transcripts
for FAM163B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM163B gene: NM_001080515.2 Unigene Cluster for FAM163B: Family with sequence similarity 163, member B Hs.741379 [show with all ESTs]Unigene Representative Sequence: NM_0010805152 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000496132 ENST00000356873(uc011mdm.2)
Additional mRNA sequence: BC146946.1 BC146961.1 2 DOTS entries: DT.100844524 DT.121151588
GeneLoc Exon Structure
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Expression
for FAM163B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM163B expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CGGGAGGCCT
About this image
See FAM163B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM163B
SOURCE GeneReport for Unigene cluster: Hs.741379
SABiosciences Custom PCR Arrays for FAM163B
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for FAM163B
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM163B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM163B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM163B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM163B |
Orthologs
for FAM163B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for FAM163B gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for FAM163B (if available)
TreeFam Gene Tree for FAM163B (if available) |
Paralogs
for FAM163B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM163B gene
- LOC1009963902 FAM163A2
1 SIMAP similar gene for FAM163B using alignment to 1 protein entry: F163B_HUMAN:FAM163A
FAM163B for paralogs About GeneDecksing
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Genomic Variants
for FAM163B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FAM163B (136443537 - 136451319 bp)
Structural Variations
Database of Genomic Variants (DGV) 10/13 variations for FAM163B (see all 13): About this table
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM163B |
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Disorders
/ Diseases
for FAM163B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM163B for disorders About MalaCards
FAM163B for disorders About GeneDecksing
Genetic Association Database (GAD): FAM163B
Export disorders for FAM163B gene to outside databases
|
Publications
for FAM163B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM163B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM163B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- Genome-wide meta-analyses identify multiple loci asso ciated with smoking behavior. (PubMed id 20418890)4 (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (2000)
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External Searches for FAM163B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM163B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM163B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM163B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM163B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM163B gene:
Search GeneIP for patents involving FAM163B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM163B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM163B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM163B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM163B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM163B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM163B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM163B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM163B |
|  |  |  |  | | | | Search ThermoFisher Antibodies for FAM163B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM163B |
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