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Aliases for FAM162B Gene

Aliases for FAM162B Gene

  • Family With Sequence Similarity 162, Member B 2 3
  • C6orf189 3 4
  • Chromosome 6 Open Reading Frame 189 2
  • Protein FAM162B 3
  • BA86F4.2 3

External Ids for FAM162B Gene

Previous Symbols for FAM162B Gene

  • C6orf189

Summaries for FAM162B Gene

GeneCards Summary for FAM162B Gene

FAM162B (Family With Sequence Similarity 162, Member B) is a Protein Coding gene. An important paralog of this gene is FAM162A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM162B Gene

Genomics for FAM162B Gene

Genomic Location for FAM162B Gene

Start:
116,752,197 bp from pter
End:
116,765,723 bp from pter
Size:
13,527 bases
Orientation:
Minus strand

Genomic View for FAM162B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM162B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM162B Gene

Regulatory Elements for FAM162B Gene

Proteins for FAM162B Gene

  • Protein details for FAM162B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T6X4-F162B_HUMAN
    Recommended name:
    Protein FAM162B
    Protein Accession:
    Q5T6X4
    Secondary Accessions:
    • Q8IXW8

    Protein attributes for FAM162B Gene

    Size:
    162 amino acids
    Molecular mass:
    17685 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH38997.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FAM162B Gene

Proteomics data for FAM162B Gene at MOPED

Post-translational modifications for FAM162B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM162B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM162B Gene

Domains for FAM162B Gene

Protein Domains for FAM162B Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F162B_HUMAN
Family:
  • Belongs to the UPF0389 family.:
    • Q5T6X4
genes like me logo Genes that share domains with FAM162B: view

No data available for Gene Families for FAM162B Gene

Function for FAM162B Gene

Phenotypes for FAM162B Gene

GenomeRNAi human phenotypes for FAM162B:
genes like me logo Genes that share phenotypes with FAM162B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM162B Gene

Localization for FAM162B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM162B Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM162B Gene COMPARTMENTS Subcellular localization image for FAM162B gene
Compartment Confidence
mitochondrion 3
cytosol 2
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FAM162B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM162B: view

Pathways for FAM162B Gene

SuperPathways for FAM162B Gene

No Data Available

Interacting Proteins for FAM162B Gene

Gene Ontology (GO) - Biological Process for FAM162B Gene

None

No data available for Pathways by source for FAM162B Gene

Transcripts for FAM162B Gene

mRNA/cDNA for FAM162B Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM162B Gene

Family with sequence similarity 162, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM162B Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4
SP1:
SP2: -

Relevant External Links for FAM162B Gene

GeneLoc Exon Structure for
FAM162B
ECgene alternative splicing isoforms for
FAM162B

Expression for FAM162B Gene

mRNA expression in normal human tissues for FAM162B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM162B Gene

SOURCE GeneReport for Unigene cluster for FAM162B Gene Hs.126712

genes like me logo Genes that share expressions with FAM162B: view

Orthologs for FAM162B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM162B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM162B 36
  • 99.79 (n)
  • 100 (a)
FAM162B 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM162B 36
  • 80.48 (n)
  • 75.66 (a)
FAM162B 37
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM162B 36
  • 87.53 (n)
  • 82.11 (a)
FAM162B 37
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam162b 36
  • 74.6 (n)
  • 68.03 (a)
Fam162b 16
Fam162b 37
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM162B 36
  • 65.31 (n)
  • 66.67 (a)
FAM162B 37
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM162B 37
  • 58 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734027 36
  • 66.99 (n)
  • 67.31 (a)
zebrafish
(Danio rerio)
Actinopterygii fam162a 37
  • 42 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9231 37
  • 25 (a)
OneToMany
Species with no ortholog for FAM162B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM162B Gene

ENSEMBL:
Gene Tree for FAM162B (if available)
TreeFam:
Gene Tree for FAM162B (if available)

Paralogs for FAM162B Gene

Paralogs for FAM162B Gene

Selected SIMAP similar genes for FAM162B Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for FAM162B Gene

genes like me logo Genes that share paralogs with FAM162B: view

Variants for FAM162B Gene

Sequence variations from dbSNP and Humsavar for FAM162B Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs548101 -- 116,762,557(-) GCATG(C/T)GAAGG intron-variant
rs590022 -- 116,763,767(-) AATAA(A/G)TAAGC intron-variant
rs590572 -- 116,763,598(-) ATAAT(G/T)TAATT intron-variant
rs590991 -- 116,761,419(-) AACTC(A/G)ATTAG intron-variant
rs603540 -- 116,763,083(-) TAGAT(A/G)GGAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM162B Gene

Variant ID Type Subtype PubMed ID
nsv523972 CNV Gain 19592680

Relevant External Links for FAM162B Gene

HapMap Linkage Disequilibrium report
FAM162B

Disorders for FAM162B Gene

Relevant External Links for FAM162B

Genetic Association Database (GAD)
FAM162B
Human Genome Epidemiology (HuGE) Navigator
FAM162B
genes like me logo Genes that share disorders with FAM162B: view

No data available for UniProtKB/Swiss-Prot for FAM162B Gene

Publications for FAM162B Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer. (PMID: 21460395) Gu J. … Wu X. (Cancer Prev Res (Phila) 2011) 3 49
  5. Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier L.D. … Marra M. (Genome Res. 1996) 3

Products for FAM162B Gene

Sources for FAM162B Gene

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