Aliases for FAM162A Gene
External Ids for FAM162A Gene
Previous Symbols for FAM162A Gene
GeneCards Summary for FAM162A Gene
FAM162A (Family With Sequence Similarity 162, Member A) is a Protein Coding gene. An important paralog of this gene is FAM162B.
UniProtKB/Swiss-Prot for FAM162A Gene
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly.