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Aliases for FAM161B Gene

Aliases for FAM161B Gene

  • Family With Sequence Similarity 161, Member B 2 3
  • C14orf44 3 4
  • Chromosome 14 Open Reading Frame 44 2
  • Protein FAM161B 3
  • C14_5547 3

External Ids for FAM161B Gene

Previous HGNC Symbols for FAM161B Gene

  • C14orf44

Previous GeneCards Identifiers for FAM161B Gene

  • GC14M073471
  • GC14M074400
  • GC14M054567

Summaries for FAM161B Gene

GeneCards Summary for FAM161B Gene

FAM161B (Family With Sequence Similarity 161, Member B) is a Protein Coding gene. Diseases associated with FAM161B include retinitis pigmentosa 28 and retinitis pigmentosa. An important paralog of this gene is FAM161A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM161B Gene

Genomics for FAM161B Gene

Regulatory Elements for FAM161B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM161B Gene

Start:
73,931,501 bp from pter
End:
73,950,414 bp from pter
Size:
18,914 bases
Orientation:
Minus strand

Genomic View for FAM161B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM161B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM161B Gene

Proteins for FAM161B Gene

  • Protein details for FAM161B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MY7-F161B_HUMAN
    Recommended name:
    Protein FAM161B
    Protein Accession:
    Q96MY7
    Secondary Accessions:
    • B7Z882
    • J3KNA2

    Protein attributes for FAM161B Gene

    Size:
    647 amino acids
    Molecular mass:
    73647 Da
    Quaternary structure:
    • Interacts with FAM161A.

    Alternative splice isoforms for FAM161B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM161B Gene

Proteomics data for FAM161B Gene at MOPED

Post-translational modifications for FAM161B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM161B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM161B Gene

Domains for FAM161B Gene

Protein Domains for FAM161B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM161B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96MY7

UniProtKB/Swiss-Prot:

F161B_HUMAN :
  • Q96MY7
Family:
  • Belongs to the FAM161 family.
genes like me logo Genes that share domains with FAM161B: view

No data available for Gene Families for FAM161B Gene

Function for FAM161B Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM161B Gene

Localization for FAM161B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM161B Gene COMPARTMENTS Subcellular localization image for FAM161B gene
Compartment Confidence
nucleus 3
cytosol 2
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM161B Gene

Pathways for FAM161B Gene

SuperPathways for FAM161B Gene

No Data Available

Interacting Proteins for FAM161B Gene

Selected Interacting proteins: Q96MY7-F161B_HUMAN for FAM161B Gene via MINT I2D

Symbol External ID(s) Details
SMAD2

Gene Ontology (GO) - Biological Process for FAM161B Gene

None

No data available for Pathways by source for FAM161B Gene

Transcripts for FAM161B Gene

mRNA/cDNA for FAM161B Gene

Unigene Clusters for FAM161B Gene

Family with sequence similarity 161, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM161B

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM161B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM161B Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7
SP1:
SP2: -
SP3:
SP4:

Relevant External Links for FAM161B Gene

GeneLoc Exon Structure for
FAM161B
ECgene alternative splicing isoforms for
FAM161B

Expression for FAM161B Gene

mRNA expression in normal human tissues for FAM161B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM161B Gene

SOURCE GeneReport for Unigene cluster for FAM161B Gene Hs.550547

mRNA Expression by UniProt/SwissProt for FAM161B Gene

Q96MY7-F161B_HUMAN
Tissue specificity: Ubiquitously expressed.
genes like me logo Genes that share expressions with FAM161B: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for FAM161B Gene

Orthologs for FAM161B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM161B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM161B 35
  • 99.15 (n)
  • 99.01 (a)
FAM161B 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM161B 35
  • 83.98 (n)
  • 77.59 (a)
FAM161B 36
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM161B 35
  • 85.57 (n)
  • 78.21 (a)
FAM161B 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam161b 35
  • 81.77 (n)
  • 78.36 (a)
Fam161b 16
Fam161b 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM161B 36
  • 56 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM161B 35
  • 61.49 (n)
  • 52.62 (a)
FAM161B 36
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM161B 36
  • 47 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam161b 35
  • 49.85 (n)
  • 42.12 (a)
zebrafish
(Danio rerio)
Actinopterygii fam161b 36
  • 33 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
OneToMany
Species with no ortholog for FAM161B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM161B Gene

ENSEMBL:
Gene Tree for FAM161B (if available)
TreeFam:
Gene Tree for FAM161B (if available)

Paralogs for FAM161B Gene

Paralogs for FAM161B Gene

genes like me logo Genes that share paralogs with FAM161B: view

Variants for FAM161B Gene

Sequence variations from dbSNP and Humsavar for FAM161B Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs740506 -- 73,942,329(-) TGCGG(C/T)CTGAA intron-variant
rs740507 -- 73,941,520(+) CTCAA(A/G)TTTCA intron-variant
rs740508 -- 73,941,500(+) TAAGG(C/T)AAGGA intron-variant
rs758241 -- 73,943,960(-) CCTTC(A/G)TCCTG intron-variant
rs758242 -- 73,942,171(-) TAAAA(A/G)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM161B Gene

Variant ID Type Subtype PubMed ID
esv274934 CNV Gain+Loss 21479260

Relevant External Links for FAM161B Gene

HapMap Linkage Disequilibrium report
FAM161B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM161B Gene

Disorders for FAM161B Gene

MalaCards: The human disease database

MalaCards: The human disease database. (2) Diseases for FAM161B Gene including...

Search for FAM161B Gene in MalaCards »

Relevant External Links for FAM161B

Genetic Association Database (GAD)
FAM161B
genes like me logo Genes that share disorders with FAM161B: view

No data available for UniProtKB/Swiss-Prot for FAM161B Gene

Publications for FAM161B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4
  4. The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule association. (PMID: 22791751) Zach F. … Stohr H. (Hum. Mol. Genet. 2012) 4
  5. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3

Products for FAM161B Gene

Sources for FAM161B Gene

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