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Aliases for FAM160B2 Gene

Aliases for FAM160B2 Gene

  • Family With Sequence Similarity 160, Member B2 2 3
  • Retinoic Acid-Induced Protein 16 3 4
  • Retinoic Acid Induced 16 2 3
  • RAI16 3 4
  • Protein FAM160B2 3

External Ids for FAM160B2 Gene

Previous HGNC Symbols for FAM160B2 Gene

  • RAI16

Previous GeneCards Identifiers for FAM160B2 Gene

  • GC08P022003
  • GC08P020466
  • GC08P021947

Summaries for FAM160B2 Gene

GeneCards Summary for FAM160B2 Gene

FAM160B2 (Family With Sequence Similarity 160, Member B2) is a Protein Coding gene. An important paralog of this gene is FAM160B1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM160B2 Gene

Genomics for FAM160B2 Gene

Regulatory Elements for FAM160B2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM160B2 Gene

Start:
22,089,159 bp from pter
End:
22,104,898 bp from pter
Size:
15,740 bases
Orientation:
Plus strand

Genomic View for FAM160B2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM160B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM160B2 Gene

Proteins for FAM160B2 Gene

  • Protein details for FAM160B2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86V87-F16B2_HUMAN
    Recommended name:
    Protein FAM160B2
    Protein Accession:
    Q86V87
    Secondary Accessions:
    • B2RDQ5
    • B3KNX1
    • Q2M211
    • Q71JB5
    • Q7L3J6
    • Q969T0
    • Q9H6W4

    Protein attributes for FAM160B2 Gene

    Size:
    743 amino acids
    Molecular mass:
    82340 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH52237.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI12148.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAI12148.2; Type=Frameshift; Positions=291; Evidence={ECO:0000305}; Sequence=AAQ06676.1; Type=Frameshift; Positions=258, 727; Evidence={ECO:0000305}; Sequence=BAB15137.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG38002.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG51483.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FAM160B2 Gene

Proteomics data for FAM160B2 Gene at MOPED

Post-translational modifications for FAM160B2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM160B2 Gene

No data available for DME Specific Peptides for FAM160B2 Gene

Domains for FAM160B2 Gene

Protein Domains for FAM160B2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM160B2 Gene

Graphical View of Domain Structure for InterPro Entry

Q86V87

UniProtKB/Swiss-Prot:

F16B2_HUMAN :
  • Q86V87
Family:
  • Belongs to the UPF0518 family.
genes like me logo Genes that share domains with FAM160B2: view

No data available for Gene Families for FAM160B2 Gene

Function for FAM160B2 Gene

Animal Model Products

CRISPR Products

miRNA for FAM160B2 Gene

miRTarBase miRNAs that target FAM160B2

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM160B2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM160B2 Gene

Localization for FAM160B2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM160B2 Gene COMPARTMENTS Subcellular localization image for FAM160B2 gene
Compartment Confidence
cytosol 2
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM160B2 Gene

Pathways for FAM160B2 Gene

SuperPathways for FAM160B2 Gene

No Data Available

Interacting Proteins for FAM160B2 Gene

Gene Ontology (GO) - Biological Process for FAM160B2 Gene

None

No data available for Pathways by source for FAM160B2 Gene

Transcripts for FAM160B2 Gene

Unigene Clusters for FAM160B2 Gene

Family with sequence similarity 160, member B2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM160B2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM160B2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM160B2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b · 16c ^ 17a ·
SP1: - - -
SP2:
SP3:
SP4:
SP5:
SP6: -
SP7:
SP8:
SP9: -
SP10:

ExUns: 17b · 17c · 17d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for FAM160B2 Gene

GeneLoc Exon Structure for
FAM160B2
ECgene alternative splicing isoforms for
FAM160B2

Expression for FAM160B2 Gene

mRNA expression in normal human tissues for FAM160B2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for FAM160B2 Gene

SOURCE GeneReport for Unigene cluster for FAM160B2 Gene Hs.491223

genes like me logo Genes that share expressions with FAM160B2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM160B2 Gene

Orthologs for FAM160B2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM160B2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM160B2 35
  • 99.46 (n)
  • 98.98 (a)
FAM160B2 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM160B2 35
  • 85.98 (n)
  • 84.53 (a)
FAM160B2 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM160B2 35
  • 84.93 (n)
  • 84.63 (a)
FAM160B2 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam160b2 35
  • 83.89 (n)
  • 86.27 (a)
Fam160b2 16
Fam160b2 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM160B2 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM160B2 36
  • 66 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam160b2 35
  • 83.49 (n)
  • 85.33 (a)
chicken
(Gallus gallus)
Aves FAM160B2 36
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM160B2 36
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam160b2 35
  • 58.36 (n)
  • 52.97 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5399 35
zebrafish
(Danio rerio)
Actinopterygii fam160b2 35
  • 55.9 (n)
  • 52.05 (a)
fam160b2 36
  • 49 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 34 (a)
OneToMany
Species with no ortholog for FAM160B2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM160B2 Gene

ENSEMBL:
Gene Tree for FAM160B2 (if available)
TreeFam:
Gene Tree for FAM160B2 (if available)

Paralogs for FAM160B2 Gene

Paralogs for FAM160B2 Gene

Selected SIMAP similar genes for FAM160B2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM160B2: view

Variants for FAM160B2 Gene

Sequence variations from dbSNP and Humsavar for FAM160B2 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1456 -- 22,094,715(-) CCGGC(A/G)GCTAA intron-variant, utr-variant-5-prime, upstream-variant-2KB
rs7490 -- 22,104,323(+) ACTTT(A/C/G/T)GCATT utr-variant-3-prime, nc-transcript-variant
rs11352 -- 22,097,605(+) AGCGT(C/T)CACAG reference, synonymous-codon, nc-transcript-variant
rs716008 -- 22,095,339(-) AGCCC(C/T)GCGCA intron-variant, upstream-variant-2KB
rs1127961 -- 22,102,310(+) TGTTG(G/T)TGAGG reference, missense, downstream-variant-500B, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM160B2 Gene

Variant ID Type Subtype PubMed ID
essv19243 CNV CNV 17122850
essv21913 CNV CNV 17122850
dgv7756n71 CNV Loss 21882294
nsv831263 CNV Loss 17160897
nsv528590 CNV Loss 19592680
dgv7757n71 CNV Loss 21882294
nsv890654 CNV Loss 21882294
nsv465613 CNV Loss 19166990
dgv7758n71 CNV Loss 21882294
nsv890657 CNV Loss 21882294
esv1008033 CNV Deletion 20482838
nsv831264 CNV Gain+Loss 17160897
dgv450n21 CNV Loss 19592680
dgv881n27 CNV Loss 19166990
nsv470204 CNV Loss 18288195
esv2736745 CNV Deletion 23290073

Relevant External Links for FAM160B2 Gene

HapMap Linkage Disequilibrium report
FAM160B2
Human Gene Mutation Database (HGMD)
FAM160B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM160B2 Gene

Disorders for FAM160B2 Gene

No disorders were found for FAM160B2 Gene.

No data available for UniProtKB/Swiss-Prot for FAM160B2 Gene

Publications for FAM160B2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Are gene expression microarray analyses reliable? A review of studies of retinoic acid responsive genes. (PMID: 15626329) van der Spek P.J. … Walker M.G. (Genomics Proteomics Bioinformatics 2003) 2 3
  3. Retinoic acid induced 16 enhances tumorigenesis and serves as a novel tumor marker for hepatocellular carcinoma. (PMID: 22971576) Wang W. … Qi Z.T. (Carcinogenesis 2012) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 4

Products for FAM160B2 Gene

Sources for FAM160B2 Gene

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