FAM160B2 Gene
protein-coding GIFtS: 41
GCID: GC08P021947
|
|
family with sequence similarity 160, member B2(Previous name: retinoic acid induced 16 )
(Previous symbol: RAI16)
| |
Aliases
for FAM160B2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 160, Member B21 2 | | RAI161 2 3 | | Retinoic Acid Induced 161 2 | | Retinoic Acid-Induced Protein 162 3 | | FLJ218011 | | Protein FAM160B22 |
Export aliases for FAM160B2 gene to outside databasesPrevious GC identifers: GC08P022003 GC08P020466 |
Summaries
for FAM160B2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM160B2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM160B2 gene promoter:
ER-alpha Spz1 AML1a MyoD C/EBPalpha CREB PPAR-alpha deltaCREB ZIC2/Zic2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM160B2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM160B2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p21.3 Ensembl cytogenetic band: 8p21.3 HGNC cytogenetic band: 8p21.3FAM160B2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P021947: view genomic region
(about GC identifiers)
Start:
|
21,946,670 bp from pter |
End:
|
21,962,232 bp from pter |
Size:
|
15,563 bases |
Orientation:
|
plus strand |
|
Proteins
for FAM160B2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F16B2_HUMAN, Q86V87 (See
protein sequence)Recommended Name: Protein FAM160B2 Size: 743 amino acids; 82340 Da
Sequence caution: Sequence=AAH52237.1; Type=Erroneous initiation; Sequence=AAI12148.2; Type=Erroneous initiation;Note=Translation N-terminally shortened; Sequence=AAI12148.2; Type=Frameshift; Positions=291; Sequence=AAQ06676.1;Type=Frameshift; Positions=258, 727; Sequence=BAB15137.1; Type=Erroneous initiation; Sequence=BAG38002.1;Type=Erroneous initiation; Sequence=BAG51483.1; Type=Erroneous initiation;
Secondary accessions: B2RDQ5 B3KNX1 Q2M211 Q71JB5 Q7L3J6 Q969T0 Q9H6W4Explore the universe of human proteins at neXtProt for FAM160B2: NX_Q86V87
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86V87
FAM160B2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_073586.5
ENSEMBL proteins: ENSP00000395477 ENSP00000403288 ENSP00000289921
Human Recombinant Protein Products:
FAM160B2 Antibody Products:
Assay Products for FAM160B2: |
Protein
Domains /
Families
for FAM160B2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM160B2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86V87ProtoNet protein and cluster: Q86V87 UniProtKB/Swiss-Prot: F16B2_HUMAN, Q86V87Similarity: Belongs to the UPF0518 family |
Function
for FAM160B2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM160B2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM160B2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM160B2 (NM_022749) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM160B2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM160B2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM160B2 |
|
Pathways & Interactions
for FAM160B2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM160B2
|
Drugs & Compounds
for FAM160B2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM160B2
Search CenterWatch for drugs/clinical trials and news about FAM160B2 / F16B2
|
Transcripts
for FAM160B2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM160B2 gene: NM_022749.5 Unigene Cluster for FAM160B2: Family with sequence similarity 160, member B2 Hs.491223 [show with all ESTs]Unigene Representative Sequence: NM_02274912 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498344 ENST00000427751 ENST00000488968(uc011kyw.1) ENST00000450006(uc011kyy.2)
ENST00000289921(uc011kyx.2) ENST00000464226 ENST00000474579 ENST00000462914
ENST00000491733 ENST00000477614 ENST00000496599 ENST00000523633
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM160B2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM160B2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM160B2 (NM_022749) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM160B2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM160B2 |
Additional cDNA sequence: AF318332.1 AF495722.1 AK001987.2 AK025411.1 AK025454.1 AK055191.1 AK294646.1 AK315634.1 BC012865.1 BC013350.2 BC112147.1 15 DOTS entries: DT.414734 DT.309991 DT.91760405 DT.75139806 DT.91653112 DT.120633252 DT.95179919 DT.91640117 DT.100791095 DT.100791096 DT.120633237 DT.120633249 DT.40264666 DT.92418649 DT.100746080 24/214 AceView cDNA sequences (see all 214): AW204785 CD515723 AA488863 BU740077 BM686932 AA488940 BM701599 AI919069 AK001987 CA454980 BM664655 BI827998 BU620979 AI183844 BM695719 BE675390 AK095924 CF272374 BM753996 AI418504 BC012865 AI923659 AI830925 AI743567
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for FAM160B2 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17b | · | 17c | · | 17d |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for FAM160B2
|
Expression
for FAM160B2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM160B2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGTGCACA
About this image
See FAM160B2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM160B2
SOURCE GeneReport for Unigene cluster: Hs.491223
SABiosciences Custom PCR Arrays for FAM160B2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM160B2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM160B2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM160B2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM160B2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM160B2 |
Orthologs
for FAM160B2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FAM160B2 gene from 3/15 species (see all 15) About this table
ENSEMBL Gene Tree for FAM160B2 (if available)
TreeFam Gene Tree for FAM160B2 (if available) |
Paralogs
for FAM160B2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM160B2 gene
- FAM160A12 FAM160B12 FAM160A22
1 SIMAP similar gene for FAM160B2 using alignment to 2 protein entries: F16B2_HUMAN (see all proteins):FAM160B1
FAM160B2 for paralogs About GeneDecksing
|
Genomic Variants
for FAM160B2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM160B2 (21946670 - 21962232 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for FAM160B2
5 CNVs: 2746 30283 53638 3726 4586 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM160B2 |
|
Disorders
/ Diseases
for FAM160B2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM160B2 for disorders About GeneDecksing
1  disease for FAM160B2: About MalaCardshypotrichosis
Export disorders for FAM160B2 gene to outside databases
|
Publications
for FAM160B2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM160B2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM160B2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Retinoic acid induced 16 enhances tumorigenesis and se rves as a novel tumor marker for hepatocellular carcinoma. (PubMed id 22971576)1, 3 Wang W....Qi Z.T. (2012)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Are gene expression microarray analyses reliable? A re view of studies of retinoic acid responsive genes. (PubMed id 15626329)1, 3 van der Spek P.J....Walker M.G. (2003)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis. (PubMed id 19122663)1 Wen Y.... Zhang X. (2009)
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)2 Wan D....Gu J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM160B2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM160B2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM160B2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM160B2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM160B2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM160B2 gene:
Search GeneIP for patents involving FAM160B2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM160B2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM160B2 | | | OriGene Protein Over-expression Lysate for FAM160B2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM160B2 | | OriGene 3'-UTR Clone for FAM160B2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM160B2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM160B2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM160B2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM160B2 | | OriGene Custom Protein Services for FAM160B2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM160B2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM160B2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM160B2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM160B2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM160B2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM160B2 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | FAM160B2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM160B2 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM160B2 |
|
|
|
|
