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Aliases for FAM160B1 Gene

Aliases for FAM160B1 Gene

  • Family With Sequence Similarity 160, Member B1 2 3
  • KIAA1600 2 3 4
  • Protein FAM160B1 3
  • BA106M7.3 3

External Ids for FAM160B1 Gene

Previous HGNC Symbols for FAM160B1 Gene

  • KIAA1600

Previous GeneCards Identifiers for FAM160B1 Gene

  • GC10P116572
  • GC10P110207

Summaries for FAM160B1 Gene

GeneCards Summary for FAM160B1 Gene

FAM160B1 (Family With Sequence Similarity 160, Member B1) is a Protein Coding gene. An important paralog of this gene is FAM160B2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM160B1 Gene

Genomics for FAM160B1 Gene

Regulatory Elements for FAM160B1 Gene

Genomic Location for FAM160B1 Gene

Start:
114,821,744 bp from pter
End:
114,899,832 bp from pter
Size:
78,089 bases
Orientation:
Plus strand

Genomic View for FAM160B1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM160B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM160B1 Gene

Proteins for FAM160B1 Gene

  • Protein details for FAM160B1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5W0V3-F16B1_HUMAN
    Recommended name:
    Protein FAM160B1
    Protein Accession:
    Q5W0V3
    Secondary Accessions:
    • Q5H9P7
    • Q5W0V2
    • Q8IY76
    • Q9HCH2

    Protein attributes for FAM160B1 Gene

    Size:
    765 amino acids
    Molecular mass:
    86558 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM160B1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM160B1 Gene

Proteomics data for FAM160B1 Gene at MOPED

Post-translational modifications for FAM160B1 Gene

  • Ubiquitination at Lys163
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM160B1 Gene

No data available for DME Specific Peptides for FAM160B1 Gene

Domains for FAM160B1 Gene

Protein Domains for FAM160B1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM160B1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5W0V3

UniProtKB/Swiss-Prot:

F16B1_HUMAN :
  • Q5W0V3
Family:
  • Belongs to the UPF0518 family.
genes like me logo Genes that share domains with FAM160B1: view

No data available for Gene Families for FAM160B1 Gene

Function for FAM160B1 Gene

Phenotypes for FAM160B1 Gene

GenomeRNAi human phenotypes for FAM160B1:
genes like me logo Genes that share phenotypes with FAM160B1: view

Animal Model Products

CRISPR Products

miRNA for FAM160B1 Gene

miRTarBase miRNAs that target FAM160B1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM160B1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM160B1 Gene

Localization for FAM160B1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM160B1 Gene COMPARTMENTS Subcellular localization image for FAM160B1 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM160B1 Gene

Pathways for FAM160B1 Gene

SuperPathways for FAM160B1 Gene

No Data Available

Interacting Proteins for FAM160B1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000358251%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000250416%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: Q5W0V3-F16B1_HUMAN ENSP00000358251 for FAM160B1 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for FAM160B1 Gene

None

No data available for Pathways by source for FAM160B1 Gene

Transcripts for FAM160B1 Gene

mRNA/cDNA for FAM160B1 Gene

Unigene Clusters for FAM160B1 Gene

Family with sequence similarity 160, member B1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM160B1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM160B1
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM160B1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
SP1:
SP2:

Relevant External Links for FAM160B1 Gene

GeneLoc Exon Structure for
FAM160B1
ECgene alternative splicing isoforms for
FAM160B1

Expression for FAM160B1 Gene

mRNA expression in normal human tissues for FAM160B1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM160B1 Gene

SOURCE GeneReport for Unigene cluster for FAM160B1 Gene Hs.192619

genes like me logo Genes that share expressions with FAM160B1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM160B1 Gene

Orthologs for FAM160B1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM160B1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM160B1 35
  • 99.55 (n)
  • 99.73 (a)
FAM160B1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM160B1 35
  • 90.68 (n)
  • 94.9 (a)
FAM160B1 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM160B1 35
  • 89.85 (n)
  • 93.46 (a)
FAM160B1 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam160b1 35
  • 83.94 (n)
  • 92.93 (a)
Fam160b1 16
Fam160b1 36
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM160B1 36
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM160B1 36
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam160b1 35
  • 84.38 (n)
  • 92.8 (a)
chicken
(Gallus gallus)
Aves FAM160B1 35
  • 81.33 (n)
  • 90.58 (a)
FAM160B1 36
  • 89 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM160B1 36
  • 86 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.13748 35
tropical clawed frog
(Silurana tropicalis)
Amphibia fam160b1 35
  • 71.28 (n)
  • 84.86 (a)
Str.20259 35
zebrafish
(Danio rerio)
Actinopterygii fam160b1 35
  • 67.74 (n)
  • 77.76 (a)
fam160b1 36
  • 77 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003125 35
  • 45.35 (n)
  • 36.04 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4709 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
OneToMany
Species with no ortholog for FAM160B1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM160B1 Gene

ENSEMBL:
Gene Tree for FAM160B1 (if available)
TreeFam:
Gene Tree for FAM160B1 (if available)

Paralogs for FAM160B1 Gene

Paralogs for FAM160B1 Gene

Selected SIMAP similar genes for FAM160B1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM160B1: view

Variants for FAM160B1 Gene

Sequence variations from dbSNP and Humsavar for FAM160B1 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs749649 -- 114,882,240(+) TCAGC(A/G)AAGAA intron-variant
rs758585 -- 114,822,801(-) CTCTG(G/T)GCTCG intron-variant
rs765173 -- 114,841,916(+) GCTAA(C/T)AATTT intron-variant
rs765174 -- 114,842,129(+) CACAG(C/T)TCACC intron-variant
rs808270 -- 114,821,727(-) ccgca(A/G)cccgg upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM160B1 Gene

Variant ID Type Subtype PubMed ID
nsv7211 OTHER Inversion 18451855
nsv518081 CNV Loss 19592680
nsv831996 CNV Gain 17160897

Relevant External Links for FAM160B1 Gene

HapMap Linkage Disequilibrium report
FAM160B1
Human Gene Mutation Database (HGMD)
FAM160B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM160B1 Gene

Disorders for FAM160B1 Gene

Relevant External Links for FAM160B1

Genetic Association Database (GAD)
FAM160B1
genes like me logo Genes that share disorders with FAM160B1: view

No data available for UniProtKB/Swiss-Prot for FAM160B1 Gene

Publications for FAM160B1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for FAM160B1 Gene

Sources for FAM160B1 Gene

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