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Aliases for FAM160A2 Gene

Aliases for FAM160A2 Gene

  • Family With Sequence Similarity 160, Member A2 2 3
  • C11orf56 3 4
  • FHIP 3 4
  • Chromosome 11 Open Reading Frame 56 2
  • FTS And Hook-Interacting Protein 3
  • Protein FAM160A2 4
  • KIAA1759 4

External Ids for FAM160A2 Gene

Previous HGNC Symbols for FAM160A2 Gene

  • C11orf56

Previous GeneCards Identifiers for FAM160A2 Gene

  • GC11M006192
  • GC11M005892

Summaries for FAM160A2 Gene

GeneCards Summary for FAM160A2 Gene

FAM160A2 (Family With Sequence Similarity 160, Member A2) is a Protein Coding gene. An important paralog of this gene is FAM160A1.

UniProtKB/Swiss-Prot for FAM160A2 Gene

  • Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).

Gene Wiki entry for FAM160A2 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM160A2 Gene

Genomics for FAM160A2 Gene

Regulatory Elements for FAM160A2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM160A2 Gene

6,211,334 bp from pter
6,234,711 bp from pter
23,378 bases
Minus strand

Genomic View for FAM160A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM160A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM160A2 Gene

Proteins for FAM160A2 Gene

  • Protein details for FAM160A2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    FTS and Hook-interacting protein
    Protein Accession:
    Secondary Accessions:
    • Q9C0A4
    • Q9H0N3
    • Q9H624

    Protein attributes for FAM160A2 Gene

    972 amino acids
    Molecular mass:
    105568 Da
    Quaternary structure:
    • Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. The FHF complex associates with the homotypic vesicular sorting complex (the HOPS complex).
    • Sequence=BAB21850.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM160A2 Gene


neXtProt entry for FAM160A2 Gene

Proteomics data for FAM160A2 Gene at MOPED

Post-translational modifications for FAM160A2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM160A2 Gene

No data available for DME Specific Peptides for FAM160A2 Gene

Domains for FAM160A2 Gene

Protein Domains for FAM160A2 Gene


Suggested Antigen Peptide Sequences for FAM160A2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8N612
  • Belongs to the UPF0518 family.
genes like me logo Genes that share domains with FAM160A2: view

No data available for Gene Families for FAM160A2 Gene

Function for FAM160A2 Gene

Molecular function for FAM160A2 Gene

UniProtKB/Swiss-Prot Function: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).

Gene Ontology (GO) - Molecular Function for FAM160A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with FAM160A2: view

Phenotypes for FAM160A2 Gene

GenomeRNAi human phenotypes for FAM160A2:
genes like me logo Genes that share phenotypes with FAM160A2: view

Animal Model Products

CRISPR Products

miRNA for FAM160A2 Gene

miRTarBase miRNAs that target FAM160A2

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM160A2 Gene

Localization for FAM160A2 Gene

Subcellular locations from

Jensen Localization Image for FAM160A2 Gene COMPARTMENTS Subcellular localization image for FAM160A2 gene
Compartment Confidence
cytosol 2
nucleus 2
endosome 1
mitochondrion 1
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for FAM160A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070695 FHF complex IDA 18799622
genes like me logo Genes that share ontologies with FAM160A2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM160A2 Gene

Pathways for FAM160A2 Gene

SuperPathways for FAM160A2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM160A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007032 endosome organization IMP 18799622
GO:0007040 lysosome organization IMP 18799622
GO:0008333 endosome to lysosome transport IMP 18799622
GO:0015031 protein transport IEA --
GO:0045022 early endosome to late endosome transport IMP 18799622
genes like me logo Genes that share ontologies with FAM160A2: view

No data available for Pathways by source for FAM160A2 Gene

Transcripts for FAM160A2 Gene

Unigene Clusters for FAM160A2 Gene

Family with sequence similarity 160, member A2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM160A2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM160A2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM160A2 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c ^ 14a · 14b ^ 15
SP2: - -
SP3: -
SP4: -
SP6: -
SP8: -

Relevant External Links for FAM160A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM160A2 Gene

mRNA expression in normal human tissues for FAM160A2 Gene

mRNA differential expression in normal tissues according to GTEx for FAM160A2 Gene

This gene is overexpressed in Whole Blood (4.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM160A2 Gene

SOURCE GeneReport for Unigene cluster for FAM160A2 Gene Hs.501793

genes like me logo Genes that share expressions with FAM160A2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM160A2 Gene

Orthologs for FAM160A2 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM160A2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM160A2 35
  • 96.42 (n)
  • 95.52 (a)
FAM160A2 36
  • 99 (a)
(Bos Taurus)
Mammalia FAM160A2 35
  • 92.63 (n)
  • 94.44 (a)
FAM160A2 36
  • 94 (a)
(Canis familiaris)
Mammalia FAM160A2 35
  • 92.41 (n)
  • 95.47 (a)
FAM160A2 36
  • 96 (a)
(Mus musculus)
Mammalia Fam160a2 35
  • 90.53 (n)
  • 93.82 (a)
Fam160a2 16
Fam160a2 36
  • 93 (a)
(Monodelphis domestica)
Mammalia FAM160A2 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia FAM160A2 36
  • 54 (a)
(Rattus norvegicus)
Mammalia Fam160a2 35
  • 91.13 (n)
  • 94.01 (a)
(Gallus gallus)
Aves FAM160A2 35
  • 67.94 (n)
  • 67.55 (a)
FAM160A2 36
  • 63 (a)
(Anolis carolinensis)
Reptilia FAM160A2 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam160a2 35
  • 66.23 (n)
  • 67.45 (a)
Str.17354 35
(Danio rerio)
Actinopterygii fam160a2 35
  • 62.16 (n)
  • 63.76 (a)
fam160a2 36
  • 45 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3558 36
  • 27 (a)
(Caenorhabditis elegans)
Secernentea C05D11.8 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10656 36
  • 35 (a)
Species with no ortholog for FAM160A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM160A2 Gene

Gene Tree for FAM160A2 (if available)
Gene Tree for FAM160A2 (if available)

Paralogs for FAM160A2 Gene

Paralogs for FAM160A2 Gene

Selected SIMAP similar genes for FAM160A2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM160A2: view

Variants for FAM160A2 Gene

Sequence variations from dbSNP and Humsavar for FAM160A2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs170524 -- 6,222,408(-) CCTGG(A/T)TGACC intron-variant
rs178966 -- 6,231,673(-) acaac(A/G)acaat intron-variant
rs325606 -- 6,222,752(-) CAGTG(A/C)CAGGA intron-variant
rs325607 -- 6,224,285(-) TATCA(A/G)TTTAG intron-variant
rs325608 -- 6,224,325(-) TCCCA(A/G)CCTTC intron-variant

Relevant External Links for FAM160A2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM160A2 Gene

Disorders for FAM160A2 Gene

No disorders were found for FAM160A2 Gene.

No data available for UniProtKB/Swiss-Prot for FAM160A2 Gene

Publications for FAM160A2 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex. (PMID: 18799622) Xu L. … Harper J.W. (Mol. Biol. Cell 2008) 3 4

Products for FAM160A2 Gene

Sources for FAM160A2 Gene

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