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Aliases for FAM160A1 Gene

Aliases for FAM160A1 Gene

  • Family With Sequence Similarity 160 Member A1 2 3 5
  • Family With Sequence Similarity 160, Member A1 2

External Ids for FAM160A1 Gene

Previous GeneCards Identifiers for FAM160A1 Gene

  • GC04P152549
  • GC04P152330
  • GC04P148055

Summaries for FAM160A1 Gene

GeneCards Summary for FAM160A1 Gene

FAM160A1 (Family With Sequence Similarity 160 Member A1) is a Protein Coding gene. An important paralog of this gene is FAM160B2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM160A1 Gene

Genomics for FAM160A1 Gene

Regulatory Elements for FAM160A1 Gene

Enhancers for FAM160A1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM160A1 on UCSC Golden Path with GeneCards custom track

Promoters for FAM160A1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM160A1 on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM160A1 Gene

151,409,156 bp from pter
151,670,503 bp from pter
261,348 bases
Plus strand

Genomic View for FAM160A1 Gene

Genes around FAM160A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM160A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM160A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM160A1 Gene

Proteins for FAM160A1 Gene

  • Protein details for FAM160A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM160A1
    Protein Accession:
    Secondary Accessions:
    • Q6ZUS2

    Protein attributes for FAM160A1 Gene

    1040 amino acids
    Molecular mass:
    116621 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH14937.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH14937.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAC86147.1; Type=Frameshift; Positions=859, 986; Evidence={ECO:0000305}; Sequence=BAC86147.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305};

neXtProt entry for FAM160A1 Gene

Proteomics data for FAM160A1 Gene at MOPED

Post-translational modifications for FAM160A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM160A1 Gene

No data available for DME Specific Peptides for FAM160A1 Gene

Domains & Families for FAM160A1 Gene

Protein Domains for FAM160A1 Gene


Suggested Antigen Peptide Sequences for FAM160A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0518 family.
  • Belongs to the UPF0518 family.
genes like me logo Genes that share domains with FAM160A1: view

No data available for Gene Families for FAM160A1 Gene

Function for FAM160A1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM160A1 Gene

Localization for FAM160A1 Gene

Subcellular locations from

Jensen Localization Image for FAM160A1 Gene COMPARTMENTS Subcellular localization image for FAM160A1 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM160A1 Gene

Pathways & Interactions for FAM160A1 Gene

SuperPathways for FAM160A1 Gene

No Data Available

Interacting Proteins for FAM160A1 Gene

Selected Interacting proteins: Q05DH4-F16A1_HUMAN for FAM160A1 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM160A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM160A1 Gene

Drugs & Compounds for FAM160A1 Gene

No Compound Related Data Available

Transcripts for FAM160A1 Gene

mRNA/cDNA for FAM160A1 Gene

(7) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM160A1 Gene

Family with sequence similarity 160, member A1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM160A1 Gene

No ASD Table

Relevant External Links for FAM160A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM160A1 Gene

mRNA expression in normal human tissues for FAM160A1 Gene

mRNA differential expression in normal tissues according to GTEx for FAM160A1 Gene

This gene is overexpressed in Muscle - Skeletal (x7.4), Skin - Sun Exposed (Lower leg) (x5.0), Skin - Not Sun Exposed (Suprapubic) (x4.9), and Esophagus - Mucosa (x4.6).

Protein differential expression in normal tissues from HIPED for FAM160A1 Gene

This gene is overexpressed in Monocytes (25.9), Neutrophil (13.5), Tlymphocyte (9.9), and Fetal gut (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for FAM160A1 Gene

SOURCE GeneReport for Unigene cluster for FAM160A1 Gene Hs.633810

genes like me logo Genes that share expression patterns with FAM160A1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM160A1 Gene

Orthologs for FAM160A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM160A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM160A1 35
  • 83.64 (n)
  • 83.61 (a)
FAM160A1 36
  • 82 (a)
(Canis familiaris)
Mammalia FAM160A1 35
  • 85.87 (n)
  • 86.51 (a)
FAM160A1 36
  • 84 (a)
(Mus musculus)
Mammalia Fam160a1 35
  • 83.28 (n)
  • 84.85 (a)
Fam160a1 16
Fam160a1 36
  • 77 (a)
(Pan troglodytes)
Mammalia FAM160A1 35
  • 99.46 (n)
  • 99.42 (a)
FAM160A1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam160a1 35
  • 81.22 (n)
  • 81.14 (a)
(Monodelphis domestica)
Mammalia FAM160A1 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia FAM160A1 36
  • 66 (a)
(Gallus gallus)
Aves FAM160A1 36
  • 72 (a)
(Anolis carolinensis)
Reptilia FAM160A1 36
  • 71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam160a1 35
  • 65.98 (n)
  • 64.49 (a)
(Danio rerio)
Actinopterygii fam160a1 35
  • 60.59 (n)
  • 59.92 (a)
fam160a1 36
  • 55 (a)
FAM160A1 (2 of 2) 36
  • 48 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3558 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea C05D11.8 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10656 36
  • 32 (a)
Species with no ortholog for FAM160A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM160A1 Gene

Gene Tree for FAM160A1 (if available)
Gene Tree for FAM160A1 (if available)

Paralogs for FAM160A1 Gene

Paralogs for FAM160A1 Gene

(1) SIMAP similar genes for FAM160A1 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with FAM160A1: view

Variants for FAM160A1 Gene

Sequence variations from dbSNP and Humsavar for FAM160A1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs875667 -- 151,604,325(+) TCCCT(A/G)CTCTT intron-variant
rs875668 -- 151,604,509(+) TTTGG(C/T)ATGAA intron-variant
rs718800 -- 151,628,155(-) CTCAG(A/T)CATTC intron-variant
rs718801 -- 151,628,095(-) ATATA(C/T)AGCAA intron-variant
rs727313 -- 151,580,008(+) tgtta(C/T)tgtac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM160A1 Gene

Variant ID Type Subtype PubMed ID
nsv880262 CNV Gain 21882294
nsv881526 CNV Gain 21882294
nsv880624 CNV Loss 21882294
nsv822774 CNV Gain 20364138
esv2611953 CNV Deletion 19546169
esv2051581 CNV Deletion 18987734
esv3948 CNV Deletion 18987735
esv2728537 CNV Deletion 23290073
esv2670825 CNV Deletion 23128226
esv2728538 CNV Deletion 23290073
nsv881342 CNV Loss 21882294
nsv830114 CNV Loss 17160897
nsv508321 CNV Loss 20534489
nsv4551 CNV Loss 18451855

Variation tolerance for FAM160A1 Gene

Gene Damage Index Score: 3.84; 58.71% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM160A1 Gene

Disorders for FAM160A1 Gene

Relevant External Links for FAM160A1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM160A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM160A1 Gene

Publications for FAM160A1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3

Products for FAM160A1 Gene

Sources for FAM160A1 Gene