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Aliases for FAM160A1 Gene

Aliases for FAM160A1 Gene

  • Family With Sequence Similarity 160 Member A1 2 3 5
  • Family With Sequence Similarity 160, Member A1 2

External Ids for FAM160A1 Gene

Previous GeneCards Identifiers for FAM160A1 Gene

  • GC04P152549
  • GC04P152330
  • GC04P148055

Summaries for FAM160A1 Gene

GeneCards Summary for FAM160A1 Gene

FAM160A1 (Family With Sequence Similarity 160 Member A1) is a Protein Coding gene. An important paralog of this gene is FAM160A2.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM160A1 Gene

Genomics for FAM160A1 Gene

Regulatory Elements for FAM160A1 Gene

Enhancers for FAM160A1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G151322 1.7 FANTOM5 Ensembl ENCODE 28.9 -84.3 -84326 4.5 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 YY1 FOS ZNF263 SP3 FAM160A1 ENSG00000251455 SH3D19 GC04P151316
GH04G151312 1 Ensembl ENCODE 13.5 -94.0 -93986 5.2 CTCF SAP130 JUN CEBPG ZBTB40 ZNF664 ZNF316 GATA3 FOS MAFK FAM160A1 PRSS48 ENSG00000250350 GATB ENSG00000251455 GC04P151316 RNU6-1282P
GH04G151483 0.9 Ensembl ENCODE 10.7 +75.9 75858 3.5 TEAD1 TEAD4 CHD1 CHD7 JUND PRDM6 HDAC2 POLR2A BCL11A POU5F1 ENSG00000251603 LOC105377486 FAM160A1 GC04M151467
GH04G151284 0.8 ENCODE 9.5 -124.0 -124006 1.4 FOXA2 JUN RBBP5 CHD7 ZNF335 GATA2 EED ZSCAN5C RELB IKZF2 FAM160A1 ENSG00000270681 GC04M151286 ENSG00000250350
GH04G151097 1.2 ENCODE 6.2 -309.1 -309106 4.5 MLX CREB3L1 AGO1 FEZF1 DMAP1 YY1 ZNF143 SP3 NFYC TBX21 RPS3A FAM160A1 SH3D19 ENSG00000270681 GC04P151107 GC04P151106 GC04P151105 GC04P151100 SNORD73B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM160A1 on UCSC Golden Path with GeneCards custom track

Promoters for FAM160A1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for FAM160A1 Gene

151,409,156 bp from pter
151,670,503 bp from pter
261,348 bases
Plus strand

Genomic View for FAM160A1 Gene

Genes around FAM160A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM160A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM160A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM160A1 Gene

Proteins for FAM160A1 Gene

  • Protein details for FAM160A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM160A1
    Protein Accession:
    Secondary Accessions:
    • Q6ZUS2

    Protein attributes for FAM160A1 Gene

    1040 amino acids
    Molecular mass:
    116621 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH14937.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH14937.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAC86147.1; Type=Frameshift; Positions=859, 986; Evidence={ECO:0000305}; Sequence=BAC86147.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305};

neXtProt entry for FAM160A1 Gene

Post-translational modifications for FAM160A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM160A1 Gene

Domains & Families for FAM160A1 Gene

Protein Domains for FAM160A1 Gene


Suggested Antigen Peptide Sequences for FAM160A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0518 family.
  • Belongs to the UPF0518 family.
genes like me logo Genes that share domains with FAM160A1: view

No data available for Gene Families for FAM160A1 Gene

Function for FAM160A1 Gene

Phenotypes for FAM160A1 Gene

genes like me logo Genes that share phenotypes with FAM160A1: view

Animal Models for FAM160A1 Gene

MGI Knock Outs for FAM160A1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FAM160A1 Gene

Localization for FAM160A1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM160A1 gene
Compartment Confidence
cytosol 3
nucleus 2
plasma membrane 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM160A1 Gene

Pathways & Interactions for FAM160A1 Gene

SuperPathways for FAM160A1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM160A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM160A1 Gene

Drugs & Compounds for FAM160A1 Gene

No Compound Related Data Available

Transcripts for FAM160A1 Gene

mRNA/cDNA for FAM160A1 Gene

(9) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM160A1 Gene

Family with sequence similarity 160, member A1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM160A1 Gene

No ASD Table

Relevant External Links for FAM160A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM160A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM160A1 Gene

mRNA differential expression in normal tissues according to GTEx for FAM160A1 Gene

This gene is overexpressed in Muscle - Skeletal (x7.4), Skin - Sun Exposed (Lower leg) (x5.0), Skin - Not Sun Exposed (Suprapubic) (x4.9), and Esophagus - Mucosa (x4.6).

Protein differential expression in normal tissues from HIPED for FAM160A1 Gene

This gene is overexpressed in Monocytes (25.9), Neutrophil (13.5), Tlymphocyte (9.9), and Fetal gut (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM160A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM160A1 Gene:


SOURCE GeneReport for Unigene cluster for FAM160A1 Gene:

genes like me logo Genes that share expression patterns with FAM160A1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM160A1 Gene

Orthologs for FAM160A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM160A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM160A1 34 35
  • 99.46 (n)
(Canis familiaris)
Mammalia FAM160A1 34 35
  • 85.87 (n)
(Bos Taurus)
Mammalia FAM160A1 34 35
  • 83.64 (n)
(Mus musculus)
Mammalia Fam160a1 34 16 35
  • 83.28 (n)
(Rattus norvegicus)
Mammalia Fam160a1 34
  • 81.22 (n)
(Monodelphis domestica)
Mammalia FAM160A1 35
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia FAM160A1 35
  • 66 (a)
(Gallus gallus)
Aves FAM160A1 35
  • 72 (a)
(Anolis carolinensis)
Reptilia FAM160A1 35
  • 71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam160a1 34
  • 65.98 (n)
(Danio rerio)
Actinopterygii fam160a1 34 35
  • 60.59 (n)
FAM160A1 (2 of 2) 35
  • 48 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3558 35
  • 26 (a)
(Caenorhabditis elegans)
Secernentea C05D11.8 35
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10656 35
  • 32 (a)
Species where no ortholog for FAM160A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM160A1 Gene

Gene Tree for FAM160A1 (if available)
Gene Tree for FAM160A1 (if available)

Paralogs for FAM160A1 Gene

Paralogs for FAM160A1 Gene

(1) SIMAP similar genes for FAM160A1 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with FAM160A1: view

Variants for FAM160A1 Gene

Sequence variations from dbSNP and Humsavar for FAM160A1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000011589 -- 151,474,321(+) TGCTC(A/G)TTATG intron-variant
rs10000281 -- 151,599,338(+) CAAGG(C/G)TGAAT intron-variant
rs1000039283 -- 151,541,486(+) CCAAT(A/G)ATATT intron-variant
rs1000040417 -- 151,500,276(+) TTCTA(C/G)GCCTC intron-variant
rs1000064233 -- 151,427,882(+) TGGGC(A/G)TTCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM160A1 Gene

Variant ID Type Subtype PubMed ID
dgv2919n106 CNV deletion 24896259
esv2051581 CNV deletion 18987734
esv2611953 CNV deletion 19546169
esv2670825 CNV deletion 23128226
esv2728537 CNV deletion 23290073
esv2728538 CNV deletion 23290073
esv3564796 CNV deletion 23714750
esv3564797 CNV deletion 23714750
esv3602685 CNV loss 21293372
esv3602687 CNV loss 21293372
esv3602688 CNV gain 21293372
esv3602690 CNV loss 21293372
esv3948 CNV loss 18987735
nsv1028814 CNV gain 25217958
nsv1074228 CNV deletion 25765185
nsv1147606 CNV deletion 26484159
nsv4551 CNV deletion 18451855
nsv474145 CNV novel sequence insertion 20440878
nsv508321 CNV deletion 20534489
nsv822774 CNV gain 20364138
nsv830114 CNV loss 17160897
nsv955629 CNV deletion 24416366

Variation tolerance for FAM160A1 Gene

Gene Damage Index Score: 3.84; 58.71% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM160A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM160A1 Gene

Disorders for FAM160A1 Gene

Relevant External Links for FAM160A1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM160A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM160A1 Gene

Publications for FAM160A1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64

Products for FAM160A1 Gene

Sources for FAM160A1 Gene

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