Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM159B Gene

Aliases for FAM159B Gene

  • Family With Sequence Similarity 159, Member B 2 3

External Ids for FAM159B Gene

Summaries for FAM159B Gene

GeneCards Summary for FAM159B Gene

FAM159B (Family With Sequence Similarity 159, Member B) is a Protein Coding gene. An important paralog of this gene is FAM159A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM159B Gene

Genomics for FAM159B Gene

Genomic Location for FAM159B Gene

Start:
64,690,308 bp from pter
End:
64,718,190 bp from pter
Size:
27,883 bases
Orientation:
Plus strand

Genomic View for FAM159B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM159B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM159B Gene

Regulatory Elements for FAM159B Gene

Proteins for FAM159B Gene

  • Protein details for FAM159B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NKW6-F159B_HUMAN
    Recommended name:
    Membrane protein FAM159B
    Protein Accession:
    A6NKW6
    Secondary Accessions:

    Protein attributes for FAM159B Gene

    Size:
    160 amino acids
    Molecular mass:
    17663 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM159B Gene

Proteomics data for FAM159B Gene at MOPED

Post-translational modifications for FAM159B Gene

No Post-translational modifications

Other Protein References for FAM159B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM159B Gene

Domains for FAM159B Gene

Protein Domains for FAM159B Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F159B_HUMAN
Family:
  • Belongs to the FAM159 family.:
    • A6NKW6
genes like me logo Genes that share domains with FAM159B: view

No data available for Gene Families for FAM159B Gene

Function for FAM159B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM159B Gene

Localization for FAM159B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM159B Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM159B Gene COMPARTMENTS Subcellular localization image for FAM159B gene
Compartment Confidence
plasma membrane 3
extracellular 2

Gene Ontology (GO) - Cellular Components for FAM159B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM159B: view

Pathways for FAM159B Gene

SuperPathways for FAM159B Gene

No Data Available

Interacting Proteins for FAM159B Gene

Gene Ontology (GO) - Biological Process for FAM159B Gene

None

No data available for Pathways by source for FAM159B Gene

Transcripts for FAM159B Gene

mRNA/cDNA for FAM159B Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM159B Gene

Family with sequence similarity 159, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM159B Gene

ExUns: 1a · 1b ^ 2 ^ 3
SP1:
SP2: -

Relevant External Links for FAM159B Gene

GeneLoc Exon Structure for
FAM159B
ECgene alternative splicing isoforms for
FAM159B

Expression for FAM159B Gene

mRNA expression in normal human tissues for FAM159B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM159B Gene

This gene is overexpressed in Pancreas (21.5) and Brain - Hypothalamus (13.6).

SOURCE GeneReport for Unigene cluster for FAM159B Gene Hs.591776

genes like me logo Genes that share expressions with FAM159B: view

Orthologs for FAM159B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM159B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM159B 36
  • 99.58 (n)
  • 100 (a)
FAM159B 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM159B 36
  • 91.04 (n)
  • 90.62 (a)
FAM159B 37
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM159B 36
  • 85.83 (n)
  • 80 (a)
FAM159B 37
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam159b 36
  • 87.05 (n)
  • 85.99 (a)
Fam159b 16
Fam159b 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM159B 37
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM159B 37
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam159b 36
  • 88.61 (n)
  • 88.61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam159b 36
  • 63.49 (n)
  • 61.9 (a)
Species with no ortholog for FAM159B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM159B Gene

ENSEMBL:
Gene Tree for FAM159B (if available)
TreeFam:
Gene Tree for FAM159B (if available)

Paralogs for FAM159B Gene

Paralogs for FAM159B Gene

Selected SIMAP similar genes for FAM159B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM159B: view

Variants for FAM159B Gene

Sequence variations from dbSNP and Humsavar for FAM159B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs182149 -- 64,697,362(-) AATCT(A/G)GTCAA intron-variant
rs183917 -- 64,716,253(-) CAAAT(A/G)ATGCA intron-variant
rs192456 -- 64,711,343(+) attta(C/T)tgatt intron-variant
rs275813 -- 64,711,455(+) ttgag(C/G)atttt intron-variant
rs275814 -- 64,713,398(+) ttctg(C/T)caaga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM159B Gene

Variant ID Type Subtype PubMed ID
dgv6083n71 CNV Gain 21882294
nsv881748 CNV Gain 21882294
esv2752074 CNV Gain 17911159

Relevant External Links for FAM159B Gene

HapMap Linkage Disequilibrium report
FAM159B

Disorders for FAM159B Gene

No disorders were found for FAM159B Gene.

No data available for UniProtKB/Swiss-Prot for FAM159B Gene

Publications for FAM159B Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4

Products for FAM159B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM159B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM159B
    • Block miRNA regulation of FAM159B using miScript Target Protectors

    Sources for FAM159B Gene

    Back to Top

    Content