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Aliases for FAM157B Gene

Aliases for FAM157B Gene

  • Family With Sequence Similarity 157, Member B 2 3

External Ids for FAM157B Gene

Summaries for FAM157B Gene

GeneCards Summary for FAM157B Gene

FAM157B (Family With Sequence Similarity 157, Member B) is a Protein Coding gene. An important paralog of this gene is FAM157A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM157B Gene

Genomics for FAM157B Gene

Genomic Location for FAM157B Gene

Start:
138,216,187 bp from pter
End:
138,252,994 bp from pter
Size:
36,808 bases
Orientation:
Plus strand

Genomic View for FAM157B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM157B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM157B Gene

Regulatory Elements for FAM157B Gene

Transcription factor binding sites by QIAGEN in the FAM157B gene promoter:

Proteins for FAM157B Gene

  • Protein details for FAM157B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG42-F157B_HUMAN
    Recommended name:
    Putative protein FAM157B
    Protein Accession:
    P0CG42
    Secondary Accessions:

    Protein attributes for FAM157B Gene

    Size:
    384 amino acids
    Molecular mass:
    43129 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM157B Gene

Proteomics data for FAM157B Gene at MOPED

Post-translational modifications for FAM157B Gene

No Post-translational modifications

Other Protein References for FAM157B Gene

REFSEQ proteins:

No data available for DME Specific Peptides for FAM157B Gene

Domains for FAM157B Gene

Protein Domains for FAM157B Gene

ProtoNet:

UniProtKB/Swiss-Prot:

F157B_HUMAN
Family:
  • Belongs to the FAM157 family.:
    • P0CG42
genes like me logo Genes that share domains with FAM157B: view

No data available for Gene Families for FAM157B Gene

Function for FAM157B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM157B Gene

Localization for FAM157B Gene

No data available for Gene Ontology (GO) - Cellular Components for FAM157B Gene

Pathways for FAM157B Gene

SuperPathways for FAM157B Gene

No Data Available

Interacting Proteins for FAM157B Gene

Gene Ontology (GO) - Biological Process for FAM157B Gene

None

No data available for Pathways by source for FAM157B Gene

Transcripts for FAM157B Gene

mRNA/cDNA for FAM157B Gene

(8) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM157B Gene

No ASD Table

Relevant External Links for FAM157B Gene

GeneLoc Exon Structure for
FAM157B
ECgene alternative splicing isoforms for
FAM157B

Expression for FAM157B Gene

mRNA expression in normal human tissues for FAM157B Gene

mRNA differential expression in normal tissues according to GTEx for FAM157B Gene

This gene is overexpressed in Whole Blood (30.8).

SOURCE GeneReport for Unigene cluster for FAM157B Gene Hs.741123

genes like me logo Genes that share expressions with FAM157B: view

Orthologs for FAM157B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM157B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100615675 36
  • 96.41 (n)
  • 91.71 (a)
Species with no ortholog for FAM157B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM157B Gene

ENSEMBL:
Gene Tree for FAM157B (if available)
TreeFam:
Gene Tree for FAM157B (if available)

Paralogs for FAM157B Gene

Paralogs for FAM157B Gene

Selected SIMAP similar genes for FAM157B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM157B: view

Variants for FAM157B Gene

Sequence variations from dbSNP and Humsavar for FAM157B Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs4335077 -- 138,231,877(-) AGATC(A/G)GTGAT intron-variant
rs4410858 -- 138,231,212(-) CCAAA(C/T)AGTGA intron-variant
rs4916937 -- 138,231,884(-) GTGGA(C/T)TAGAT intron-variant
rs7389790 -- 138,214,649(+) AGTGC(G/T)ATTTC upstream-variant-2KB
rs7848839 -- 138,219,333(+) TGCTT(C/T)GGTCC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for FAM157B Gene

Variant ID Type Subtype PubMed ID
dgv2429e1 CNV Complex 17122850
nsv894683 CNV Gain 21882294
esv27764 CNV Gain+Loss 19812545
dgv8465n71 CNV Gain 21882294
dgv2430e1 CNV Complex 17122850
nsv8590 CNV Gain+Loss 18304495
esv33178 CNV Gain 17666407
esv1009101 CNV Deletion 20482838

Relevant External Links for FAM157B Gene

HapMap Linkage Disequilibrium report
FAM157B

Disorders for FAM157B Gene

No disorders were found for FAM157B Gene.

No data available for UniProtKB/Swiss-Prot for FAM157B Gene

Publications for FAM157B Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for FAM157B Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM157B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM157B
    • Block miRNA regulation of FAM157B using miScript Target Protectors

    Sources for FAM157B Gene

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