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Aliases for FAM157A Gene

Aliases for FAM157A Gene

  • Family With Sequence Similarity 157, Member A 2 3

External Ids for FAM157A Gene

Previous GeneCards Identifiers for FAM157A Gene

  • GC03P199364
  • GC03P197879

Summaries for FAM157A Gene

GeneCards Summary for FAM157A Gene

FAM157A (Family With Sequence Similarity 157, Member A) is a Protein Coding gene. An important paralog of this gene is FAM157B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM157A Gene

Genomics for FAM157A Gene

Regulatory Elements for FAM157A Gene

Transcription factor binding sites by QIAGEN in the FAM157A gene promoter:

Genomic Location for FAM157A Gene

198,151,974 bp from pter
198,211,810 bp from pter
59,837 bases
Plus strand

Genomic View for FAM157A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for FAM157A Gene

Proteins for FAM157A Gene

  • Protein details for FAM157A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative protein FAM157A
    Protein Accession:

    Protein attributes for FAM157A Gene

    383 amino acids
    Molecular mass:
    42896 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM157A Gene

Proteomics data for FAM157A Gene at MOPED

Post-translational modifications for FAM157A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM157A Gene

REFSEQ proteins:

No data available for DME Specific Peptides for FAM157A Gene

Domains & Families for FAM157A Gene

Protein Domains for FAM157A Gene


Suggested Antigen Peptide Sequences for FAM157A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM157 family.
  • Belongs to the FAM157 family.
genes like me logo Genes that share domains with FAM157A: view

No data available for Gene Families for FAM157A Gene

Function for FAM157A Gene

Phenotypes for FAM157A Gene

GenomeRNAi human phenotypes for FAM157A:
genes like me logo Genes that share phenotypes with FAM157A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM157A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM157A Gene

Localization for FAM157A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM157A Gene

Pathways & Interactions for FAM157A Gene

SuperPathways for FAM157A Gene

No Data Available

Interacting Proteins for FAM157A Gene

Gene Ontology (GO) - Biological Process for FAM157A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM157A Gene

Drugs & Compounds for FAM157A Gene

No Compound Related Data Available

Transcripts for FAM157A Gene

mRNA/cDNA for FAM157A Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM157A Gene

Family with sequence similarity 157, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM157A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM157A Gene

No ASD Table

Relevant External Links for FAM157A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM157A Gene

mRNA expression in normal human tissues for FAM157A Gene

mRNA differential expression in normal tissues according to GTEx for FAM157A Gene

This gene is overexpressed in Whole Blood (x25.1).

Protein differential expression in normal tissues from HIPED for FAM157A Gene

This gene is overexpressed in Urine (57.2) and Adipocyte (11.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM157A Gene

SOURCE GeneReport for Unigene cluster for FAM157A Gene Hs.744675

genes like me logo Genes that share expression patterns with FAM157A: view

Protein tissue co-expression partners for FAM157A Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM157A Gene

Orthologs for FAM157A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM157A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC100615675 35
  • 96.4 (n)
  • 91.97 (a)
Species with no ortholog for FAM157A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM157A Gene

Gene Tree for FAM157A (if available)
Gene Tree for FAM157A (if available)

Paralogs for FAM157A Gene

Paralogs for FAM157A Gene

(2) SIMAP similar genes for FAM157A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM157A: view

Variants for FAM157A Gene

Sequence variations from dbSNP and Humsavar for FAM157A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs940483 -- 198,152,987(-) ACTGA(C/G)GATCC intron-variant
rs1052171 -- 198,171,670(+) gagcc(A/C)ttagc intron-variant
rs1132104 -- 198,171,734(+) gacac(C/G)cagct intron-variant
rs2021178 -- 198,153,348(-) TTTGC(A/G)AGGCC reference, missense
rs2257852 -- 198,163,944(-) AAAAG(A/G)AGCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM157A Gene

Variant ID Type Subtype PubMed ID
esv33797 CNV Gain+Loss 17666407
dgv5381n71 CNV Gain 21882294
dgv1562e1 CNV Complex 17122850
dgv5383n71 CNV Gain 21882294
esv26652 CNV Gain+Loss 19812545
nsv820948 CNV Duplication 20802225
nsv10407 CNV Gain 18304495
nsv471429 CNV Duplication 19718026
nsv482085 CNV Gain 20164927
nsv10408 CNV Gain+Loss 18304495
esv6783 CNV Loss 19470904

Relevant External Links for FAM157A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM157A Gene

Disorders for FAM157A Gene

Relevant External Links for FAM157A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM157A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM157A Gene

Publications for FAM157A Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 67

Products for FAM157A Gene

Sources for FAM157A Gene

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