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Aliases for FAM155B Gene

Aliases for FAM155B Gene

  • Family With Sequence Similarity 155 Member B 2 3 5
  • Transmembrane Protein 28 2 3 4
  • Family With Sequence Similarity 155, Member B 2 3
  • TMEM28 3 4
  • TED 3 4
  • Chromosome X Open Reading Frame 63 2
  • BB57D9.1 (TED Protein) 3
  • Protein TED 4
  • BB57D9.1 3
  • CXorf63 3

External Ids for FAM155B Gene

Previous HGNC Symbols for FAM155B Gene

  • TMEM28
  • CXorf63

Previous GeneCards Identifiers for FAM155B Gene

  • GC0XP068643
  • GC0XP062546
  • GC0XP068725

Summaries for FAM155B Gene

Entrez Gene Summary for FAM155B Gene

  • This gene encodes a product belonging to a family of proteins with unknown function. The presence of two transmembrane domains suggests that this protein is a multi-pass membrane protein. [provided by RefSeq, Sep 2011]

GeneCards Summary for FAM155B Gene

FAM155B (Family With Sequence Similarity 155 Member B) is a Protein Coding gene. Diseases associated with FAM155B include Enterobiasis and Marantic Endocarditis. An important paralog of this gene is FAM155A.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM155B Gene

Genomics for FAM155B Gene

Regulatory Elements for FAM155B Gene

Enhancers for FAM155B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM155B on UCSC Golden Path with GeneCards custom track

Promoters for FAM155B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM155B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM155B Gene

Chromosome:
X
Start:
69,505,201 bp from pter
End:
69,532,508 bp from pter
Size:
27,308 bases
Orientation:
Plus strand

Genomic View for FAM155B Gene

Genes around FAM155B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM155B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM155B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM155B Gene

Proteins for FAM155B Gene

  • Protein details for FAM155B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75949-F155B_HUMAN
    Recommended name:
    Transmembrane protein FAM155B
    Protein Accession:
    O75949
    Secondary Accessions:
    • B1ALV6
    • B9EGK1
    • D3DVU1

    Protein attributes for FAM155B Gene

    Size:
    473 amino acids
    Molecular mass:
    52605 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM155B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM155B Gene

Proteomics data for FAM155B Gene at MOPED

Post-translational modifications for FAM155B Gene

  • Glycosylation at Asn 120 and Asn 193
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM155B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM155B Gene

Domains & Families for FAM155B Gene

Protein Domains for FAM155B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM155B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75949

UniProtKB/Swiss-Prot:

F155B_HUMAN :
  • Belongs to the FAM155 family.
Family:
  • Belongs to the FAM155 family.
genes like me logo Genes that share domains with FAM155B: view

No data available for Gene Families for FAM155B Gene

Function for FAM155B Gene

Phenotypes for FAM155B Gene

genes like me logo Genes that share phenotypes with FAM155B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM155B Gene

Localization for FAM155B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM155B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM155B Gene COMPARTMENTS Subcellular localization image for FAM155B gene
Compartment Confidence
extracellular 3
endoplasmic reticulum 1
golgi apparatus 1
lysosome 1
plasma membrane 1
vacuole 1

No data available for Gene Ontology (GO) - Cellular Components for FAM155B Gene

Pathways & Interactions for FAM155B Gene

SuperPathways for FAM155B Gene

No Data Available

Interacting Proteins for FAM155B Gene

Gene Ontology (GO) - Biological Process for FAM155B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM155B Gene

Drugs & Compounds for FAM155B Gene

No Compound Related Data Available

Transcripts for FAM155B Gene

mRNA/cDNA for FAM155B Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM155B Gene

Family with sequence similarity 155, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM155B Gene

No ASD Table

Relevant External Links for FAM155B Gene

GeneLoc Exon Structure for
FAM155B
ECgene alternative splicing isoforms for
FAM155B

Expression for FAM155B Gene

mRNA expression in normal human tissues for FAM155B Gene

mRNA differential expression in normal tissues according to GTEx for FAM155B Gene

This gene is overexpressed in Heart - Atrial Appendage (x17.8) and Heart - Left Ventricle (x12.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM155B Gene



SOURCE GeneReport for Unigene cluster for FAM155B Gene Hs.87619

genes like me logo Genes that share expression patterns with FAM155B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM155B Gene

Orthologs for FAM155B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM155B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM155B 35
  • 93.56 (n)
  • 91.72 (a)
FAM155B 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM155B 35
  • 93.93 (n)
  • 93.86 (a)
FAM155B 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem28 35
  • 93.56 (n)
  • 94.06 (a)
Tmem28 16
Tmem28 36
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam155b 35
  • 93.63 (n)
  • 94.27 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM155B 36
  • 53 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM155B 35
  • 67.9 (n)
  • 58.46 (a)
FAM155B 36
  • 48 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam155b 35
  • 64.25 (n)
  • 58.55 (a)
zebrafish
(Danio rerio)
Actinopterygii fam155b 35
  • 54.89 (n)
  • 44.86 (a)
fam155b 36
  • 41 (a)
OneToOne
Species with no ortholog for FAM155B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM155B Gene

ENSEMBL:
Gene Tree for FAM155B (if available)
TreeFam:
Gene Tree for FAM155B (if available)

Paralogs for FAM155B Gene

Paralogs for FAM155B Gene

genes like me logo Genes that share paralogs with FAM155B: view

Variants for FAM155B Gene

Sequence variations from dbSNP and Humsavar for FAM155B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1171942 - 69,505,797(+) CTCCC(C/T)TTCCC nc-transcript-variant, reference, missense
rs747824084 -- 69,529,535(+) CTCCC(C/T)GAGCA intron-variant
rs747844935 -- 69,529,191(+) AGAGG(C/G)AGGAG intron-variant
rs747878590 -- 69,519,899(+) CACCA(A/T)AATGA intron-variant
rs748014661 -- 69,513,637(+) ATCTT(-/ATA)ATAAT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM155B Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER Inversion 17803354
esv25466 CNV Loss 19812545
esv23322 CNV Gain 19812545

Variation tolerance for FAM155B Gene

Residual Variation Intolerance Score: 44.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.42; 42.72% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM155B Gene

Disorders for FAM155B Gene

MalaCards: The human disease database

(2) MalaCards diseases for FAM155B Gene - From: DISEASES

Disorder Aliases PubMed IDs
enterobiasis
  • enterobius vermicularis infection
marantic endocarditis
  • non-bacterial thrombotic endocarditis
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for FAM155B

Genetic Association Database (GAD)
FAM155B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM155B
genes like me logo Genes that share disorders with FAM155B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FAM155B Gene

Publications for FAM155B Gene

  1. Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. (PMID: 20195514) Pillas D. … Jarvelin M.R. (PLoS Genet. 2010) 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM155B Gene

Sources for FAM155B Gene

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