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Aliases for FAM153C Gene

Aliases for FAM153C Gene

  • Family With Sequence Similarity 153 Member C 2 5
  • Family With Sequence Similarity 153, Member C 2 3
  • Family With Sequence Similarity 153, Member C, Pseudogene 3
  • NY-REN-7-Like 3

External Ids for FAM153C Gene

Previous GeneCards Identifiers for FAM153C Gene

  • GC05P177369
  • GC05P177435
  • GC05P172169
  • GC05P177437
  • GC05P177440
  • GC05P177445
  • GC05P177448
  • GC05P177451

Summaries for FAM153C Gene

GeneCards Summary for FAM153C Gene

FAM153C (Family With Sequence Similarity 153 Member C) is a Pseudogene. An important paralog of this gene is FAM153B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM153C Gene

Genomics for FAM153C Gene

Regulatory Elements for FAM153C Gene

Enhancers for FAM153C Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM153C on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM153C Gene

178,006,405 bp from pter
178,055,559 bp from pter
49,155 bases
Plus strand

Genomic View for FAM153C Gene

Genes around FAM153C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM153C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM153C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM153C Gene

Proteins for FAM153C Gene

  • Protein details for FAM153C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM153C
    Protein Accession:
    Secondary Accessions:
    • A4IF33
    • B2RUV5
    • B7ZW12

    Protein attributes for FAM153C Gene

    144 amino acids
    Molecular mass:
    16640 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM153C Gene


neXtProt entry for FAM153C Gene

Proteomics data for FAM153C Gene at MOPED

Post-translational modifications for FAM153C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM153C Gene

No data available for DME Specific Peptides for FAM153C Gene

Domains & Families for FAM153C Gene

Protein Domains for FAM153C Gene


Suggested Antigen Peptide Sequences for FAM153C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM153 family.
  • Belongs to the FAM153 family.
genes like me logo Genes that share domains with FAM153C: view

No data available for Gene Families for FAM153C Gene

Function for FAM153C Gene

Phenotypes for FAM153C Gene

GenomeRNAi human phenotypes for FAM153C:
genes like me logo Genes that share phenotypes with FAM153C: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM153C Gene

Localization for FAM153C Gene

Subcellular locations from

Jensen Localization Image for FAM153C Gene COMPARTMENTS Subcellular localization image for FAM153C gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM153C Gene

Pathways & Interactions for FAM153C Gene

SuperPathways for FAM153C Gene

No Data Available

Interacting Proteins for FAM153C Gene

Selected Interacting proteins: Q494X1-F153C_HUMAN for FAM153C Gene via UniProtKB

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM153C Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM153C Gene

Drugs & Compounds for FAM153C Gene

No Compound Related Data Available

Transcripts for FAM153C Gene

mRNA/cDNA for FAM153C Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM153C Gene

Family with sequence similarity 153, member C, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM153C Gene

No ASD Table

Relevant External Links for FAM153C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM153C Gene

mRNA expression in normal human tissues for FAM153C Gene

mRNA differential expression in normal tissues according to GTEx for FAM153C Gene

This gene is overexpressed in Brain - Cerebellum (x8.7), Brain - Cerebellar Hemisphere (x8.0), Testis (x5.2), and Pituitary (x5.0).

SOURCE GeneReport for Unigene cluster for FAM153C Gene Hs.652193

genes like me logo Genes that share expression patterns with FAM153C: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM153C Gene

Orthologs for FAM153C Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM153C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 35 (a)
-- 36
  • 97 (a)
Species with no ortholog for FAM153C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM153C Gene

Gene Tree for FAM153C (if available)
Gene Tree for FAM153C (if available)

Paralogs for FAM153C Gene

Paralogs for FAM153C Gene

(2) SIMAP similar genes for FAM153C Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM153C: view

Variants for FAM153C Gene

Sequence variations from dbSNP and Humsavar for FAM153C Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs6601201 -- 178,037,447(+) AACAT(A/G)GAGAA intron-variant
rs6860804 -- 178,039,529(+) TGAAT(C/G)AGGAC intron-variant
rs6866401 -- 178,042,411(+) gtaat(C/T)ccagc intron-variant
rs6866556 -- 178,042,496(+) ccatc(G/T)ctcct intron-variant
rs4077782 -- 178,044,164(-) CATAC(G/T)GGAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM153C Gene

Variant ID Type Subtype PubMed ID
nsv883184 CNV Gain 21882294
nsv509105 CNV Insertion 20534489
nsv883186 CNV Gain 21882294
nsv883188 CNV Gain 21882294

Variation tolerance for FAM153C Gene

Gene Damage Index Score: 0.07; 1.61% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM153C Gene

Disorders for FAM153C Gene

Relevant External Links for FAM153C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM153C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM153C Gene

Publications for FAM153C Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM153C Gene

Sources for FAM153C Gene