Aliases for FAM153C Gene
Aliases for FAM153C Gene
External Ids for FAM153C Gene
- HGNC: 33936
- Entrez Gene: 653316
- Ensembl: ENSG00000204677
- UniProtKB: Q494X1
Previous GeneCards Identifiers for FAM153C Gene
- GC05P177369
- GC05P177435
- GC05P172169
- GC05P177437
- GC05P177440
- GC05P177445
- GC05P177448
- GC05P177451
Summaries for FAM153C Gene
GeneCards Summary for FAM153C Gene
FAM153C (Family With Sequence Similarity 153 Member C) is a Pseudogene. An important paralog of this gene is FAM153B.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM153C Gene
Genomics for FAM153C Gene
Regulatory Elements for FAM153C Gene
Enhancers for FAM153C Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH05G177591 | 1.1 | ENCODE | 17.2 | -414.0 | -413975 | 1.8 | CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF207 ZNF143 ZNF263 | FAM153C TMED9 B4GALT7 |
| GH05G177606 | 0.9 | ENCODE | 18.5 | -398.9 | -398944 | 1.9 | RB1 ARID4B SIN3A KLF17 ZNF2 ZNF48 RAD21 SCRT2 ZNF143 MIXL1 | B4GALT7 FAM153C LOC202181 FAM153A TMED9 ENSG00000247679 |
| GH05G178077 | 1.1 | Ensembl ENCODE | 10.1 | +72.0 | 72002 | 1.2 | HDGF PKNOX1 NFIB AGO1 SIN3A ZBTB7B EGR1 FOS RCOR1 HCFC1 | RMND5B N4BP3 FAM153C RPL19P9 CLK4 LOC105377754 PIR41367 |
| GH05G178086 | 1.1 | ENCODE dbSUPER | 7.8 | +80.1 | 80109 | 0.7 | HDGF PKNOX1 NFIB SIN3A ZBTB7B ELK1 EGR1 HSF1 FOS RCOR1 | N4BP3 RMND5B FAM153C RPL19P9 LOC105377754 PIR41367 |
| GH05G177615 | 0.4 | FANTOM5 | 19.4 | -390.5 | -390514 | 0.6 | FAM153C ENSG00000247679 B4GALT7 TMED9 NSD1 FAM193B PIR49975 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM153C on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FAM153C Gene
- Chromosome:
- 5
- Start:
- 178,006,405 bp from pter
- End:
- 178,055,559 bp from pter
- Size:
- 49,155 bases
- Orientation:
- Plus strand
Genomic View for FAM153C Gene
Genes around FAM153C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q35.3 by Ensembl
- 5q35.3 by Entrez Gene
- 5q35.3 by HGNC
FAM153C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM153C Gene
Proteins for FAM153C Gene
-
Protein details for FAM153C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q494X1-F153C_HUMAN
- Recommended name:
- Protein FAM153C
- Protein Accession:
- Q494X1
- A4IF33
- B2RUV5
- B7ZW12
Protein attributes for FAM153C Gene
- Size:
- 144 amino acids
- Molecular mass:
- 16640 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for FAM153C Gene
Other Protein References for FAM153C Gene
- ENSEMBL proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FAM153C
-
Abcam antibodies for FAM153C
- Search GeneTex for Antibodies for FAM153C
Protein Products
-
OriGene Purified Proteins for FAM153C
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No data available for DME Specific Peptides for FAM153C Gene
Domains & Families for FAM153C Gene
Suggested Antigen Peptide Sequences for FAM153C Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q494X1- Family:
-
- Belongs to the FAM153 family.
No data available for Gene Families for FAM153C Gene
Function for FAM153C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for FAM153C Gene
- GenomeRNAi human phenotypes for FAM153C:
Animal Model Products
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-
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CRISPR Products
-
OriGene CRISPR knockouts for FAM153C
-
Applied Biological Materials CRISPR for FAM153C
miRNA Products
- Search ViGene Biosciences for FAM153C
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM153C
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Clone Products
-
OriGene ORF clones in human for FAM153C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM153C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM153C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM153C Gene
Localization for FAM153C Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| extracellular | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM153C Gene
Transcripts for FAM153C Gene
mRNA/cDNA for FAM153C Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM153C Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM153C
-
Applied Biological Materials CRISPR for FAM153C
miRNA Products
- Search ViGene Biosciences for FAM153C
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM153C
- Browse OriGene Inhibitory RNA Products For FAM153C
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Clone Products
-
OriGene ORF clones in human for FAM153C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM153C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM153C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for FAM153C Gene
mRNA differential expression in normal tissues according to GTEx for FAM153C Gene
This gene is overexpressed in Brain - Cerebellum (x8.7), Brain - Cerebellar Hemisphere (x8.0), Testis (x5.2), and Pituitary (x5.0).
NURSA nuclear receptor signaling pathways regulating expression of FAM153C Gene:
FAM153CSOURCE GeneReport for Unigene cluster for FAM153C Gene:
Hs.652193Primer Products
-
OriGene qPCR primer pairs for FAM153C
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM153C Gene
Orthologs for FAM153C Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany |
- Species where no ortholog for FAM153C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM153C Gene
(2) SIMAP similar genes for FAM153C Gene using alignment to 4 proteins:
Variants for FAM153C Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000040781 | -- | 178,024,758(+) | TTGCC(G/T)GTTCA | intron-variant | |
| rs1000300940 | -- | 178,044,264(+) | GCCAA(A/G)AGTCT | intron-variant, downstream-variant-500B | |
| rs1000339723 | -- | 178,005,583(+) | ATGAA(A/G)TGCTG | upstream-variant-2KB | |
| rs1000481726 | -- | 178,016,005(+) | ACTGT(A/G)TACTC | intron-variant | |
| rs1000496265 | -- | 178,015,820(+) | GAGAA(C/T)TGACT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5844n100 | CNV | gain | 25217958 |
| nsv1115711 | CNV | duplication | 24896259 |
| nsv1120062 | OTHER | inversion | 24896259 |
| nsv509105 | CNV | insertion | 20534489 |
| nsv950729 | CNV | deletion | 24416366 |
| nsv968283 | CNV | duplication | 23825009 |
| nsv968284 | CNV | duplication | 23825009 |
| nsv969026 | CNV | duplication | 23825009 |
| nsv969092 | CNV | duplication | 23825009 |
| nsv980768 | CNV | duplication | 23825009 |
Gene Damage Index Score:
0.07;
1.61% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM153C Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM153C
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM153C Gene
Disorders for FAM153C Gene
Relevant External Links for FAM153C
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM153C
No disorders were found for FAM153C Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM153C Gene
Publications for FAM153C Gene
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for FAM153C Gene
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- Custom Antibody ServicesOriGene Antibodies for FAM153C
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- OriGene Purified Proteins for FAM153C
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- OriGene qPCR primer pairs for FAM153C
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- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM153C
- VectorBuilder custom plasmid, inducible vectors for FAM153C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM153C
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM153C Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
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- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
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- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
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- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
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- (141) ENCODE
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- (152) ProteoGenix
- (153) dbSUPER
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- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio