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Aliases for FAM153B Gene

Aliases for FAM153B Gene

  • Family With Sequence Similarity 153, Member B 2 3

External Ids for FAM153B Gene

Previous GeneCards Identifiers for FAM153B Gene

  • GC05P175444
  • GC05P175511
  • GC05P170477

Summaries for FAM153B Gene

GeneCards Summary for FAM153B Gene

FAM153B (Family With Sequence Similarity 153, Member B) is a Protein Coding gene. An important paralog of this gene is FAM153C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM153B Gene

Genomics for FAM153B Gene

Regulatory Elements for FAM153B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM153B Gene

Start:
176,060,689 bp from pter
End:
176,132,258 bp from pter
Size:
71,570 bases
Orientation:
Plus strand

Genomic View for FAM153B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM153B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM153B Gene

Proteins for FAM153B Gene

  • Protein details for FAM153B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7A2-F153B_HUMAN
    Recommended name:
    Protein FAM153B
    Protein Accession:
    P0C7A2
    Secondary Accessions:
    • A8MTI1

    Protein attributes for FAM153B Gene

    Size:
    387 amino acids
    Molecular mass:
    43591 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH28606.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM153B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM153B Gene

Proteomics data for FAM153B Gene at MOPED

Post-translational modifications for FAM153B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM153B Gene

No data available for DME Specific Peptides for FAM153B Gene

Domains for FAM153B Gene

Protein Domains for FAM153B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM153B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7A2

UniProtKB/Swiss-Prot:

F153B_HUMAN :
  • P0C7A2
Family:
  • Belongs to the FAM153 family.
genes like me logo Genes that share domains with FAM153B: view

No data available for Gene Families for FAM153B Gene

Function for FAM153B Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM153B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM153B Gene

Localization for FAM153B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM153B Gene COMPARTMENTS Subcellular localization image for FAM153B gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM153B Gene

Pathways for FAM153B Gene

SuperPathways for FAM153B Gene

No Data Available

Interacting Proteins for FAM153B Gene

Gene Ontology (GO) - Biological Process for FAM153B Gene

None

No data available for Pathways by source for FAM153B Gene

Transcripts for FAM153B Gene

mRNA/cDNA for FAM153B Gene

(5) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(21) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM153B Gene

Family with sequence similarity 153, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM153B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM153B Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1: -
SP2: - -
SP3: - - - - -
SP4:

Relevant External Links for FAM153B Gene

GeneLoc Exon Structure for
FAM153B
ECgene alternative splicing isoforms for
FAM153B

Expression for FAM153B Gene

mRNA expression in normal human tissues for FAM153B Gene

mRNA differential expression in normal tissues according to GTEx for FAM153B Gene

This gene is overexpressed in Brain - Cerebellum (5.7), Brain - Cerebellar Hemisphere (5.2), and Ovary (4.6).

SOURCE GeneReport for Unigene cluster for FAM153B Gene Hs.368516

genes like me logo Genes that share expressions with FAM153B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for FAM153B Gene

Orthologs for FAM153B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM153B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 75 (a)
ManyToMany
-- 36
  • 97 (a)
ManyToMany
FAM153B 35
  • 97.63 (n)
  • 93.87 (a)
Species with no ortholog for FAM153B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM153B Gene

ENSEMBL:
Gene Tree for FAM153B (if available)
TreeFam:
Gene Tree for FAM153B (if available)

Paralogs for FAM153B Gene

Paralogs for FAM153B Gene

Selected SIMAP similar genes for FAM153B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM153B: view

Variants for FAM153B Gene

Sequence variations from dbSNP and Humsavar for FAM153B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs869567 -- 176,098,789(+) GTCCT(C/T)AGGAG intron-variant
rs1966016 -- 176,107,653(-) TGTTT(G/T)ACATT intron-variant
rs2334806 -- 176,095,936(+) TGCTC(A/T)AAGGC intron-variant
rs2334811 -- 176,112,443(+) ACAGT(A/G)GTCAC intron-variant
rs4269301 -- 176,086,397(+) TTGTC(C/G)CAGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM153B Gene

Variant ID Type Subtype PubMed ID
nsv883122 CNV Gain 21882294
dgv6371n71 CNV Gain 21882294
dgv1876e1 CNV Complex 17122850
esv34563 CNV Gain 17911159
nsv883126 CNV Gain 21882294
dgv1877e1 CNV Complex 17122850
dgv6373n71 CNV Gain 21882294
nsv883133 CNV Gain 21882294
nsv883134 CNV Gain 21882294
esv2421778 CNV Duplication 20811451
nsv441977 CNV CNV 18776908
dgv6374n71 CNV Gain 21882294
nsv428131 CNV Gain 18775914
nsv883137 CNV Loss 21882294
nsv10778 CNV Loss 18304495

Relevant External Links for FAM153B Gene

HapMap Linkage Disequilibrium report
FAM153B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM153B Gene

Disorders for FAM153B Gene

No disorders were found for FAM153B Gene.

No data available for UniProtKB/Swiss-Prot for FAM153B Gene

Publications for FAM153B Gene

  1. A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library. (PMID: 9776767) BA1ssow K. … Walter G. (Nucleic Acids Res. 1998) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4

Products for FAM153B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM153B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM153B
    • Block miRNA regulation of FAM153B using miScript Target Protectors

    Sources for FAM153B Gene

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