FAM153A Gene
protein-coding GIFtS: 43
GCID: GC05M177134
|
|
family with sequence similarity 153, member A
| |
Aliases
for FAM153A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 153, Member A1 2 | | NY-REN-71 2 | | Renal Carcinoma Antigen NY-REN-72 3 | | NY REN 7 Antigen2 | | Protein FAM153A2 | | KIAA07523 |
Export aliases for FAM153A gene to outside databasesPrevious GC identifers: GC05M177071 GC05P172197 |
Summaries
for FAM153A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM153A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM153A gene promoter:
TBP RORalpha1 ISGF-3 IRF-7A GATA-1 RORalpha2
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM153A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM153A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35.3FAM153A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M177134: view genomic region
(about GC identifiers)
Start:
|
177,134,982 bp from pter |
End:
|
177,210,399 bp from pter |
Size:
|
75,418 bases |
Orientation:
|
minus strand |
|
Proteins
for FAM153A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F153A_HUMAN, Q9UHL3 (See
protein sequence)Recommended Name: Protein FAM153A Size: 310 amino acids; 34712 Da
Sequence caution: Sequence=BAA34472.1; Type=Erroneous initiation;
Secondary accessions: A8K0F3 O94852Explore the universe of human proteins at neXtProt for FAM153A: NX_Q9UHL3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UHL3
FAM153A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775934.3
ENSEMBL proteins: ENSP00000353887 ENSP00000422174 ENSP00000411506 ENSP00000426689 ENSP00000421623 ENSP00000425931 ENSP00000424904 ENSP00000423766 ENSP00000425021 ENSP00000377153
Human Recombinant Protein Products:
FAM153A Antibody Products:
Assay Products for FAM153A: |
Protein
Domains /
Families
for FAM153A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM153A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9UHL3ProtoNet protein and cluster: Q9UHL3 UniProtKB/Swiss-Prot: F153A_HUMAN, Q9UHL3Similarity: Belongs to the FAM153 family |
Function
for FAM153A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM153A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM153A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM153A (NM_173663) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM153A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM153A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM153A |
1 GenomeRNAi human phenotype for FAM153A:
|
Pathways & Interactions
for FAM153A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM153A
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for FAM153A (Q9UHL33 ENSP000003538874) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for FAM153A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM153A
Search CenterWatch for drugs/clinical trials and news about FAM153A / F153A
|
Transcripts
for FAM153A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM153A gene: NM_173663.3 Unigene Cluster for FAM153A: Family with sequence similarity 153, member A Hs.652754 [show with all ESTs]Unigene Representative Sequence: AF15509718/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000506011 ENST00000360669(uc003mib.1 uc021yix.1 uc010jkp.1)
ENST00000509607 ENST00000514899 ENST00000510276 ENST00000512544 ENST00000440605(uc003mic.3)
ENST00000513554 ENST00000505531 ENST00000512612 ENST00000515787 ENST00000503845
ENST00000504518 ENST00000505683 ENST00000503909 ENST00000507615 ENST00000506354
ENST00000503567
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM153A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM153A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM153A (NM_173663) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM153A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM153A |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM153A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM153A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM153A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM153A |
Additional cDNA sequence: AF155097.1 AK289518.1 4 DOTS entries: DT.91669153 DT.120872254 DT.120872242 DT.87009802 12 AceView cDNA sequences: AI684503 AL042189 AW665256 BQ428949 BQ711500 AA353592 CB998646 AL046089 BV189207 AW269432 BE763409 AI480077
GeneLoc Exon Structure
|
Expression
for FAM153A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM153A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM153A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM153A
SOURCE GeneReport for Unigene cluster: Hs.652754
SABiosciences Custom PCR Arrays for FAM153A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM153A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM153A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM153A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM153A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM153A |
Orthologs
for FAM153A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for FAM153A (if available)
TreeFam Gene Tree for FAM153A (if available) |
Paralogs
for FAM153A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM153A gene
- FAM153B2 FAM153C2
2 SIMAP similar genes for FAM153A using alignment to 8 protein entries: F153A_HUMAN (see all proteins):FAM153C FAM153B
FAM153A for paralogs About GeneDecksing
|
Genomic Variants
for FAM153A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM153A (177134982 - 177210399 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for FAM153A
5 CNVs: 51644 38797 36375 69252 7487 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM153A |
|
Disorders
/ Diseases
for FAM153A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM153A for disorders About GeneDecksing
3  diseases for FAM153A: About MalaCardsrenal carcinoma carcinoma renal cell carcinoma
Export disorders for FAM153A gene to outside databases
|
Publications
for FAM153A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM153A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM153A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2, 3 Scanlan M.J....Old L.J. (1999)
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2, 3 Nagase T.... Ohara O. (1998)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM153A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM153A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM153A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing FAM153A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM153A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM153A gene:
Search GeneIP for patents involving FAM153A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM153A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM153A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM153A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM153A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM153A | | OriGene 3'-UTR Clone for FAM153A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM153A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM153A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM153A | | OriGene Custom Protein Services for FAM153A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM153A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM153A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM153A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM153A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM153A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM153A |
| |
 |  |  |  | |
| | | | Search Tocris compounds for FAM153A |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | FAM153A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM153A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM153A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM153A |
|
|
|
|
