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Aliases for FAM153A Gene

Aliases for FAM153A Gene

  • Family With Sequence Similarity 153 Member A 2 3 5
  • Family With Sequence Similarity 153, Member A 2 3
  • Renal Carcinoma Antigen NY-REN-7 3 4
  • NY REN 7 Antigen 2 3
  • NY-REN-7 3
  • KIAA0752 4

External Ids for FAM153A Gene

Previous GeneCards Identifiers for FAM153A Gene

  • GC05M177071
  • GC05P172197
  • GC05M177134

Summaries for FAM153A Gene

GeneCards Summary for FAM153A Gene

FAM153A (Family With Sequence Similarity 153 Member A) is a Protein Coding gene. An important paralog of this gene is FAM153C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM153A Gene

Genomics for FAM153A Gene

Regulatory Elements for FAM153A Gene

Enhancers for FAM153A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM153A on UCSC Golden Path with GeneCards custom track

Promoters for FAM153A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM153A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM153A Gene

177,707,981 bp from pter
177,783,398 bp from pter
75,418 bases
Minus strand

Genomic View for FAM153A Gene

Genes around FAM153A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM153A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM153A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM153A Gene

Proteins for FAM153A Gene

  • Protein details for FAM153A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM153A
    Protein Accession:
    Secondary Accessions:
    • A8K0F3
    • O94852

    Protein attributes for FAM153A Gene

    310 amino acids
    Molecular mass:
    34712 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA34472.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FAM153A Gene

Proteomics data for FAM153A Gene at MOPED

Post-translational modifications for FAM153A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM153A Gene

Domains & Families for FAM153A Gene

Protein Domains for FAM153A Gene


Suggested Antigen Peptide Sequences for FAM153A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM153 family.
  • Belongs to the FAM153 family.
genes like me logo Genes that share domains with FAM153A: view

No data available for Gene Families for FAM153A Gene

Function for FAM153A Gene

Phenotypes for FAM153A Gene

GenomeRNAi human phenotypes for FAM153A:
genes like me logo Genes that share phenotypes with FAM153A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM153A Gene

Localization for FAM153A Gene

Subcellular locations from

Jensen Localization Image for FAM153A Gene COMPARTMENTS Subcellular localization image for FAM153A gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM153A Gene

Pathways & Interactions for FAM153A Gene

SuperPathways for FAM153A Gene

No Data Available

Interacting Proteins for FAM153A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000353887 Q9UHL3-F153A_HUMAN for FAM153A Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM153A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM153A Gene

Drugs & Compounds for FAM153A Gene

No Compound Related Data Available

Transcripts for FAM153A Gene

mRNA/cDNA for FAM153A Gene

Unigene Clusters for FAM153A Gene

Family with sequence similarity 153, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM153A Gene

No ASD Table

Relevant External Links for FAM153A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM153A Gene

mRNA expression in normal human tissues for FAM153A Gene

mRNA differential expression in normal tissues according to GTEx for FAM153A Gene

This gene is overexpressed in Brain - Cerebellum (x4.8), Brain - Cerebellar Hemisphere (x4.4), and Spleen (x4.3).

SOURCE GeneReport for Unigene cluster for FAM153A Gene Hs.652754

genes like me logo Genes that share expression patterns with FAM153A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM153A Gene

Orthologs for FAM153A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM153A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM153B 35
  • 97.31 (n)
  • 93.23 (a)
-- 36
  • 75 (a)
-- 36
  • 96 (a)
Species with no ortholog for FAM153A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM153A Gene

Gene Tree for FAM153A (if available)
Gene Tree for FAM153A (if available)

Paralogs for FAM153A Gene

Paralogs for FAM153A Gene

(2) SIMAP similar genes for FAM153A Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with FAM153A: view

Variants for FAM153A Gene

Sequence variations from dbSNP and Humsavar for FAM153A Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs870107 -- 177,741,444(+) TAACT(A/G)CAAAA intron-variant
rs870108 -- 177,741,451(+) AAAAA(A/C)GGACC intron-variant
rs904690 -- 177,728,645(+) tcacc(G/T)caacc intron-variant
rs904703 -- 177,739,118(+) CGTTG(G/T)TTGGG intron-variant, reference, missense
rs904705 -- 177,740,345(+) GCTCA(C/T)GCTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM153A Gene

Variant ID Type Subtype PubMed ID
nsv883182 CNV Gain 21882294
nsv519647 CNV Loss 19592680
esv33718 CNV Gain 17666407
nsv442969 CNV CNV 18776908
nsv508389 CNV Loss 20534489
nsv5150 CNV Loss 18451855
esv25576 CNV Gain+Loss 19812545

Variation tolerance for FAM153A Gene

Gene Damage Index Score: 6.34; 76.77% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM153A Gene

Disorders for FAM153A Gene

Relevant External Links for FAM153A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM153A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM153A Gene

Publications for FAM153A Gene

  1. Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PMID: 10508479) Scanlan M.J. … Old L.J. (Int. J. Cancer 1999) 2 3 4 67
  2. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 9872452) Nagase T. … Ohara O. (DNA Res. 1998) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for FAM153A Gene

Sources for FAM153A Gene