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Aliases for FAM151A Gene

Aliases for FAM151A Gene

  • Family With Sequence Similarity 151 Member A 2 3 5
  • Family With Sequence Similarity 151, Member A 2 3
  • C1orf179 3 4
  • Chromosome 1 Open Reading Frame 179 2
  • Hyporthetical Protein MGC27169 3

External Ids for FAM151A Gene

Previous HGNC Symbols for FAM151A Gene

  • C1orf179

Previous GeneCards Identifiers for FAM151A Gene

  • GC01M054847
  • GC01M055074
  • GC01M053189

Summaries for FAM151A Gene

GeneCards Summary for FAM151A Gene

FAM151A (Family With Sequence Similarity 151 Member A) is a Protein Coding gene. Diseases associated with FAM151A include renal hypodysplasia. An important paralog of this gene is FAM151B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM151A Gene

Genomics for FAM151A Gene

Regulatory Elements for FAM151A Gene

Genomic Location for FAM151A Gene

54,609,177 bp from pter
54,623,556 bp from pter
14,380 bases
Minus strand

Genomic View for FAM151A Gene

Genes around FAM151A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM151A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM151A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM151A Gene

Proteins for FAM151A Gene

  • Protein details for FAM151A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM151A
    Protein Accession:
    Secondary Accessions:
    • Q5VUG5
    • Q6DKH5
    • Q6UWV0
    • Q8NAX9
    • Q96KY5

    Protein attributes for FAM151A Gene

    585 amino acids
    Molecular mass:
    64028 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM151A Gene


neXtProt entry for FAM151A Gene

Proteomics data for FAM151A Gene at MOPED

Post-translational modifications for FAM151A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM151A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM151A Gene

Domains & Families for FAM151A Gene

Protein Domains for FAM151A Gene


Suggested Antigen Peptide Sequences for FAM151A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM151 family.
  • Belongs to the FAM151 family.
genes like me logo Genes that share domains with FAM151A: view

No data available for Gene Families for FAM151A Gene

Function for FAM151A Gene

genes like me logo Genes that share phenotypes with FAM151A: view

Animal Model Products

  • Taconic Biosciences Mouse Models for FAM151A

CRISPR Products

miRNA for FAM151A Gene

miRTarBase miRNAs that target FAM151A

miRNA Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM151A Gene

Localization for FAM151A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM151A Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FAM151A Gene COMPARTMENTS Subcellular localization image for FAM151A gene
Compartment Confidence
extracellular 5
nucleus 2
plasma membrane 2
endoplasmic reticulum 1
golgi apparatus 1
lysosome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for FAM151A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM151A: view

Pathways & Interactions for FAM151A Gene

SuperPathways for FAM151A Gene

No Data Available

Interacting Proteins for FAM151A Gene

Gene Ontology (GO) - Biological Process for FAM151A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM151A Gene

Drugs & Compounds for FAM151A Gene

No Compound Related Data Available

Transcripts for FAM151A Gene

mRNA/cDNA for FAM151A Gene

Unigene Clusters for FAM151A Gene

Family with sequence similarity 151, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM151A Gene

No ASD Table

Relevant External Links for FAM151A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM151A Gene

mRNA expression in normal human tissues for FAM151A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM151A Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x22.9) and Kidney - Cortex (x20.2).

Protein differential expression in normal tissues from HIPED for FAM151A Gene

This gene is overexpressed in Urine (34.2), Pancreatic juice (10.2), Kidney (8.8), Fetal gut (7.3), and Lymph node (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM151A Gene

SOURCE GeneReport for Unigene cluster for FAM151A Gene Hs.234786

genes like me logo Genes that share expression patterns with FAM151A: view

Protein tissue co-expression partners for FAM151A Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM151A Gene

Orthologs for FAM151A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM151A Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia FAM151A 35
  • 80.34 (n)
  • 73.16 (a)
FAM151A 36
  • 67 (a)
(Mus musculus)
Mammalia Fam151a 35
  • 77.61 (n)
  • 71.28 (a)
Fam151a 16
Fam151a 36
  • 68 (a)
(Pan troglodytes)
Mammalia FAM151A 35
  • 96.24 (n)
  • 95.04 (a)
FAM151A 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Fam151a 35
  • 76.35 (n)
  • 70.94 (a)
(Bos Taurus)
Mammalia FAM151A 36
  • 73 (a)
(Monodelphis domestica)
Mammalia FAM151A 36
  • 72 (a)
(Anolis carolinensis)
Reptilia FAM151A 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam151a 35
  • 53.86 (n)
  • 47.33 (a)
(Danio rerio)
Actinopterygii fam151a 35
  • 54.03 (n)
  • 46.86 (a)
fam151a 36
  • 41 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7231 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea mnr-1 36
  • 15 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
Species with no ortholog for FAM151A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM151A Gene

Gene Tree for FAM151A (if available)
Gene Tree for FAM151A (if available)

Paralogs for FAM151A Gene

Paralogs for FAM151A Gene

(1) SIMAP similar genes for FAM151A Gene using alignment to 2 proteins: Pseudogenes for FAM151A Gene

genes like me logo Genes that share paralogs with FAM151A: view

Variants for FAM151A Gene

Sequence variations from dbSNP and Humsavar for FAM151A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_037109 -
VAR_037110 -
VAR_037111 -
VAR_037112 -
VAR_037113 -

Structural Variations from Database of Genomic Variants (DGV) for FAM151A Gene

Variant ID Type Subtype PubMed ID
nsv461561 CNV Gain 19166990
nsv829904 CNV Loss 17160897
nsv516654 CNV Loss 19592680
nsv817614 CNV Gain 22305530
nsv461594 CNV Gain 19166990
dgv229n71 CNV Gain 21882294
nsv910 CNV Loss 18451855
esv2748330 CNV Deletion 23290073
esv33550 CNV Gain+Loss 17666407

Variation tolerance for FAM151A Gene

Residual Variation Intolerance Score: 96.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.86; 87.00% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM151A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM151A Gene

Disorders for FAM151A Gene

MalaCards: The human disease database

(1) MalaCards diseases for FAM151A Gene - From: GeneCards

Disorder Aliases PubMed IDs
renal hypodysplasia
  • renal hypoplasia, isolated
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for FAM151A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM151A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FAM151A Gene

Publications for FAM151A Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Localization of a gene for nonsyndromic renal hypodysplasia to chromosome 1p32-33. (PMID: 17273976) Sanna-Cherchi S. … Gharavi A.G. (Am. J. Hum. Genet. 2007) 2 3
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  4. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. (PMID: 23533145) Principe S. … Drake R.R. (Proteomics 2013) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for FAM151A Gene

Sources for FAM151A Gene

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