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Aliases for FAM150B Gene

Aliases for FAM150B Gene

  • Family With Sequence Similarity 150 Member B 2 3 5
  • Family With Sequence Similarity 150, Member B 2 3
  • PRO1097 3
  • RGPG542 3

External Ids for FAM150B Gene

Summaries for FAM150B Gene

GeneCards Summary for FAM150B Gene

FAM150B (Family With Sequence Similarity 150 Member B) is a Protein Coding gene. An important paralog of this gene is FAM150A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM150B Gene

Genomics for FAM150B Gene

Regulatory Elements for FAM150B Gene

Promoters for FAM150B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM150B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM150B Gene

Chromosome:
2
Start:
279,558 bp from pter
End:
288,880 bp from pter
Size:
9,323 bases
Orientation:
Minus strand

Genomic View for FAM150B Gene

Genes around FAM150B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM150B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM150B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM150B Gene

Proteins for FAM150B Gene

  • Protein details for FAM150B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UX46-F150B_HUMAN
    Recommended name:
    Protein FAM150B
    Protein Accession:
    Q6UX46
    Secondary Accessions:
    • B5MC76

    Protein attributes for FAM150B Gene

    Size:
    152 amino acids
    Molecular mass:
    16915 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM150B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM150B Gene

Proteomics data for FAM150B Gene at MOPED

Post-translational modifications for FAM150B Gene

No Post-translational modifications

Other Protein References for FAM150B Gene

No data available for DME Specific Peptides for FAM150B Gene

Domains & Families for FAM150B Gene

Protein Domains for FAM150B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM150B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UX46

UniProtKB/Swiss-Prot:

F150B_HUMAN :
  • Belongs to the FAM150 family.
Family:
  • Belongs to the FAM150 family.
genes like me logo Genes that share domains with FAM150B: view

No data available for Gene Families for FAM150B Gene

Function for FAM150B Gene

Phenotypes for FAM150B Gene

genes like me logo Genes that share phenotypes with FAM150B: view

Animal Model Products

CRISPR Products

miRNA for FAM150B Gene

miRTarBase miRNAs that target FAM150B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM150B Gene

Localization for FAM150B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM150B Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM150B Gene COMPARTMENTS Subcellular localization image for FAM150B gene
Compartment Confidence
extracellular 5

No data available for Gene Ontology (GO) - Cellular Components for FAM150B Gene

Pathways & Interactions for FAM150B Gene

SuperPathways for FAM150B Gene

No Data Available

Interacting Proteins for FAM150B Gene

Gene Ontology (GO) - Biological Process for FAM150B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM150B Gene

Drugs & Compounds for FAM150B Gene

No Compound Related Data Available

Transcripts for FAM150B Gene

Unigene Clusters for FAM150B Gene

Family with sequence similarity 150, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM150B Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1: - - - -
SP2: -
SP3: -
SP4:

Relevant External Links for FAM150B Gene

GeneLoc Exon Structure for
FAM150B
ECgene alternative splicing isoforms for
FAM150B

Expression for FAM150B Gene

mRNA expression in normal human tissues for FAM150B Gene

mRNA differential expression in normal tissues according to GTEx for FAM150B Gene

This gene is overexpressed in Adrenal Gland (x8.5), Ovary (x4.8), and Pancreas (x4.3).

Protein differential expression in normal tissues from HIPED for FAM150B Gene

This gene is overexpressed in Testis (44.9) and Ovary (24.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM150B Gene



SOURCE GeneReport for Unigene cluster for FAM150B Gene Hs.355207

genes like me logo Genes that share expression patterns with FAM150B: view

Protein tissue co-expression partners for FAM150B Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM150B Gene

Orthologs for FAM150B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM150B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM150B 35
  • 82.11 (n)
  • 82.11 (a)
mouse
(Mus musculus)
Mammalia Fam150b 35
  • 78.59 (n)
  • 81.3 (a)
Fam150b 16
Fam150b 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM150B 35
  • 99.34 (n)
  • 98.68 (a)
FAM150B 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam150b 35
  • 79.13 (n)
  • 82.11 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM150B 36
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM150B 36
  • 50 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM150B 35
  • 69.52 (n)
  • 72.65 (a)
FAM150B 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM150B 36
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam150b 35
  • 63.96 (n)
  • 59.46 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100329254 35
  • 57.65 (n)
  • 54.1 (a)
fam150ba 36
  • 43 (a)
OneToMany
fam150bb 36
  • 35 (a)
OneToMany
Species with no ortholog for FAM150B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM150B Gene

ENSEMBL:
Gene Tree for FAM150B (if available)
TreeFam:
Gene Tree for FAM150B (if available)

Paralogs for FAM150B Gene

Paralogs for FAM150B Gene

(1) SIMAP similar genes for FAM150B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM150B: view

Variants for FAM150B Gene

Sequence variations from dbSNP and Humsavar for FAM150B Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs7568664 -- 280,939(+) CTGCC(A/G)TCCTT intron-variant
rs7605824 -- 280,819(+) AACGC(A/G)GCAAA intron-variant
rs10193373 -- 281,886(+) CTGTG(C/G/T)GACAC intron-variant
rs10182453 -- 280,938(+) CCTGC(C/T)ATCCT intron-variant
rs12714404 -- 282,462(+) CTGTC(G/T)AAAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM150B Gene

Variant ID Type Subtype PubMed ID
nsv873529 CNV Gain 21882294
nsv833159 CNV Loss 17160897
essv2780 CNV CNV 17122850
dgv1137e1 CNV Complex 17122850
nsv873530 CNV Gain 21882294
nsv873531 CNV Gain 21882294
essv3569 CNV CNV 17122850
nsv833170 CNV Loss 17160897

Variation tolerance for FAM150B Gene

Gene Damage Index Score: 0.08; 1.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM150B Gene

HapMap Linkage Disequilibrium report
FAM150B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM150B Gene

Disorders for FAM150B Gene

Relevant External Links for FAM150B

Genetic Association Database (GAD)
FAM150B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM150B

No disorders were found for FAM150B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM150B Gene

Publications for FAM150B Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4 67
  2. Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome. (PMID: 25331893) Zhang H. … Williams L.T. (Proc. Natl. Acad. Sci. U.S.A. 2014) 3
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for FAM150B Gene

Sources for FAM150B Gene

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