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Aliases for FAM150A Gene

Aliases for FAM150A Gene

  • Family With Sequence Similarity 150, Member A 2 3
  • RPLK9433 3
  • UNQ9433 3

External Ids for FAM150A Gene

Previous GeneCards Identifiers for FAM150A Gene

  • GC08M053611
  • GC08M053446
  • GC08M048914

Summaries for FAM150A Gene

GeneCards Summary for FAM150A Gene

FAM150A (Family With Sequence Similarity 150, Member A) is a Protein Coding gene. An important paralog of this gene is FAM150B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM150A Gene

Genomics for FAM150A Gene

Regulatory Elements for FAM150A Gene

Genomic Location for FAM150A Gene

Chromosome:
8
Start:
52,534,037 bp from pter
End:
52,565,507 bp from pter
Size:
31,471 bases
Orientation:
Minus strand

Genomic View for FAM150A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM150A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM150A Gene

Proteins for FAM150A Gene

  • Protein details for FAM150A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXT8-F150A_HUMAN
    Recommended name:
    Protein FAM150A
    Protein Accession:
    Q6UXT8
    Secondary Accessions:
    • B7ZMG9

    Protein attributes for FAM150A Gene

    Size:
    129 amino acids
    Molecular mass:
    14269 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM150A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM150A Gene

Proteomics data for FAM150A Gene at MOPED

Post-translational modifications for FAM150A Gene

  • Glycosylation at Thr 85
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM150A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM150A Gene

Domains & Families for FAM150A Gene

Protein Domains for FAM150A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM150A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UXT8

UniProtKB/Swiss-Prot:

F150A_HUMAN :
  • Belongs to the FAM150 family.
Family:
  • Belongs to the FAM150 family.
genes like me logo Genes that share domains with FAM150A: view

No data available for Gene Families for FAM150A Gene

Function for FAM150A Gene

Phenotypes for FAM150A Gene

GenomeRNAi human phenotypes for FAM150A:
genes like me logo Genes that share phenotypes with FAM150A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM150A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM150A Gene

Localization for FAM150A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM150A Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM150A Gene COMPARTMENTS Subcellular localization image for FAM150A gene
Compartment Confidence
extracellular 3

Gene Ontology (GO) - Cellular Components for FAM150A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM150A: view

Pathways & Interactions for FAM150A Gene

SuperPathways for FAM150A Gene

No Data Available

Interacting Proteins for FAM150A Gene

Gene Ontology (GO) - Biological Process for FAM150A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM150A Gene

Drugs & Compounds for FAM150A Gene

No Compound Related Data Available

Transcripts for FAM150A Gene

mRNA/cDNA for FAM150A Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM150A Gene

Family with sequence similarity 150, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM150A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM150A Gene

No ASD Table

Relevant External Links for FAM150A Gene

GeneLoc Exon Structure for
FAM150A
ECgene alternative splicing isoforms for
FAM150A

Expression for FAM150A Gene

mRNA expression in normal human tissues for FAM150A Gene

mRNA differential expression in normal tissues according to GTEx for FAM150A Gene

This gene is overexpressed in Thyroid (x7.5), Esophagus - Muscularis (x7.3), and Bladder (x6.0).

SOURCE GeneReport for Unigene cluster for FAM150A Gene Hs.527111

genes like me logo Genes that share expression patterns with FAM150A: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM150A Gene

Orthologs for FAM150A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM150A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM150A 35
  • 81.51 (n)
  • 79.83 (a)
dog
(Canis familiaris)
Mammalia LOC608857 35
  • 87.15 (n)
  • 83.33 (a)
FAM150A 36
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam150a 35
  • 85.39 (n)
  • 80.9 (a)
Fam150a 16
Fam150a 36
  • 72 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM150A 35
  • 99.74 (n)
  • 99.22 (a)
FAM150A 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100910984 35
  • 84.27 (n)
  • 79.78 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM150A 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM150A 36
  • 77 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii FAM150A 36
  • 38 (a)
OneToOne
Species with no ortholog for FAM150A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM150A Gene

ENSEMBL:
Gene Tree for FAM150A (if available)
TreeFam:
Gene Tree for FAM150A (if available)

Paralogs for FAM150A Gene

Paralogs for FAM150A Gene

(1) SIMAP similar genes for FAM150A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM150A: view

Variants for FAM150A Gene

Sequence variations from dbSNP and Humsavar for FAM150A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs879285 -- 52,567,197(+) GCAAA(A/C)CACTT upstream-variant-2KB
rs1440797 -- 52,535,383(-) tttgg(G/T)ggcaa intron-variant
rs1440798 -- 52,534,696(-) ACAGA(G/T)TCTTT intron-variant
rs1992361 -- 52,567,366(+) TAGTT(A/C)TGAAG upstream-variant-2KB
rs2033934 -- 52,552,089(-) gacat(A/G)atgac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM150A Gene

Variant ID Type Subtype PubMed ID
dgv7794n71 CNV Gain 21882294
nsv890902 CNV Gain 21882294
nsv890903 CNV Gain 21882294
dgv7795n71 CNV Gain 21882294
nsv890906 CNV Gain 21882294
nsv890907 CNV Gain 21882294
nsv465680 CNV Gain 19166990
nsv470213 CNV Gain 18288195

Variation tolerance for FAM150A Gene

Residual Variation Intolerance Score: 47.16% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.54; 11.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM150A Gene

HapMap Linkage Disequilibrium report
FAM150A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM150A Gene

Disorders for FAM150A Gene

Relevant External Links for FAM150A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM150A
genes like me logo Genes that share disorders with FAM150A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM150A Gene

Publications for FAM150A Gene

  1. Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome. (PMID: 25331893) Zhang H. … Williams L.T. (Proc. Natl. Acad. Sci. U.S.A. 2014) 67
  2. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for FAM150A Gene

Sources for FAM150A Gene

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