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Aliases for FAM149A Gene

Aliases for FAM149A Gene

  • Family With Sequence Similarity 149, Member A 2 3
  • Protein FAM149A 3
  • MSTP119 3
  • MST119 3

External Ids for FAM149A Gene

Previous GeneCards Identifiers for FAM149A Gene

  • GC04P187304
  • GC04P187026
  • GC04P182817

Summaries for FAM149A Gene

GeneCards Summary for FAM149A Gene

FAM149A (Family With Sequence Similarity 149, Member A) is a Protein Coding gene. An important paralog of this gene is FAM149B1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM149A Gene

Genomics for FAM149A Gene

Regulatory Elements for FAM149A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM149A Gene

186,104,419 bp from pter
186,172,667 bp from pter
68,249 bases
Plus strand

Genomic View for FAM149A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM149A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM149A Gene

Proteins for FAM149A Gene

  • Protein details for FAM149A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM149A
    Protein Accession:
    Secondary Accessions:
    • B5MDB8
    • Q2TAN6
    • Q7Z2S5
    • Q9Y4T9

    Protein attributes for FAM149A Gene

    773 amino acids
    Molecular mass:
    82698 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI10817.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAQ13641.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAQ13641.1; Type=Frameshift; Positions=635; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM149A Gene


neXtProt entry for FAM149A Gene

Proteomics data for FAM149A Gene at MOPED

Post-translational modifications for FAM149A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM149A Gene

Domains for FAM149A Gene

Protein Domains for FAM149A Gene


Suggested Antigen Peptide Sequences for FAM149A Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM149 family.
  • Belongs to the FAM149 family.
genes like me logo Genes that share domains with FAM149A: view

No data available for Gene Families for FAM149A Gene

Function for FAM149A Gene

Animal Model Products

CRISPR Products

miRNA for FAM149A Gene

miRTarBase miRNAs that target FAM149A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM149A Gene

Localization for FAM149A Gene

Subcellular locations from

Jensen Localization Image for FAM149A Gene COMPARTMENTS Subcellular localization image for FAM149A gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM149A Gene

Pathways for FAM149A Gene

SuperPathways for FAM149A Gene

No Data Available

Interacting Proteins for FAM149A Gene

Selected Interacting proteins: A5PLN7-F149A_HUMAN for FAM149A Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM149A Gene


No data available for Pathways by source for FAM149A Gene

Transcripts for FAM149A Gene

Unigene Clusters for FAM149A Gene

Family with sequence similarity 149, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM149A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c
SP2: -
SP3: -

Relevant External Links for FAM149A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM149A Gene

mRNA expression in normal human tissues for FAM149A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for FAM149A Gene

This gene is overexpressed in Testis (52.5) and Adipocyte (13.8).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM149A Gene

SOURCE GeneReport for Unigene cluster for FAM149A Gene Hs.744961

genes like me logo Genes that share expressions with FAM149A: view

Expression partners for FAM149A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM149A Gene

Orthologs for FAM149A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM149A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM149A 35
  • 77.8 (n)
  • 69.94 (a)
FAM149A 36
  • 41 (a)
(Canis familiaris)
Mammalia FAM149A 35
  • 79.9 (n)
  • 71.93 (a)
FAM149A 36
  • 59 (a)
(Mus musculus)
Mammalia Fam149a 35
  • 73.7 (n)
  • 68.48 (a)
Fam149a 16
Fam149a 36
  • 41 (a)
(Pan troglodytes)
Mammalia FAM149A 35
  • 98.5 (n)
  • 95.76 (a)
(Rattus norvegicus)
Mammalia Fam149a 35
  • 73.88 (n)
  • 68.07 (a)
(Monodelphis domestica)
Mammalia FAM149A 36
  • 38 (a)
(Ornithorhynchus anatinus)
Mammalia FAM149A 36
  • 35 (a)
(Gallus gallus)
Aves FAM149A 35
  • 59.96 (n)
  • 50.31 (a)
FAM149A 36
  • 38 (a)
(Anolis carolinensis)
Reptilia FAM149A 36
  • 37 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam149a 35
  • 59.27 (n)
  • 51.8 (a)
(Danio rerio)
Actinopterygii si:ch211-51g4.5 35
  • 48.61 (n)
  • 37.04 (a)
FAM149A 36
  • 23 (a)
Species with no ortholog for FAM149A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM149A Gene

Gene Tree for FAM149A (if available)
Gene Tree for FAM149A (if available)

Paralogs for FAM149A Gene

Paralogs for FAM149A Gene

genes like me logo Genes that share paralogs with FAM149A: view

Variants for FAM149A Gene

Sequence variations from dbSNP and Humsavar for FAM149A Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs876332 -- 186,145,486(-) CAAAA(A/T)TTTCT intron-variant
rs907438 -- 186,145,044(-) GGCAC(C/G)GTCAG utr-variant-5-prime, intron-variant
rs1398009 -- 186,129,495(+) GATTC(C/T)GCTTC intron-variant
rs1398010 -- 186,129,600(+) TGACC(A/T)GCAAA intron-variant
rs1398011 -- 186,129,817(+) GTACA(C/T)GTCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM149A Gene

Variant ID Type Subtype PubMed ID
dgv683n27 CNV Gain 19166990
dgv5851n71 CNV Gain 21882294
nsv470097 CNV Gain 18288195
dgv5852n71 CNV Gain 21882294
nsv461864 CNV Gain 19166990
nsv830172 CNV Loss 17160897
dgv5853n71 CNV Loss 21882294
nsv508340 CNV Loss 20534489
esv2728928 CNV Deletion 23290073
nsv524972 CNV Loss 19592680
nsv4642 CNV Loss 18451855
esv33576 CNV Gain 17666407
esv991339 CNV Deletion 20482838
dgv47n50 CNV Loss 21212237
dgv99n16 CNV Deletion 17901297
esv2568129 CNV Deletion 19546169
dgv996e199 CNV Deletion 23128226
nsv820150 CNV Gain 19587683
dgv916n67 CNV Loss 20364138
nsv820551 CNV Deletion 20802225
esv270972 CNV Insertion 20981092
esv274663 CNV Insertion 20981092
dgv135e180 CNV Gain 20482838
esv27795 CNV Gain 19812545
esv32667 CNV Gain 17666407
nsv514284 CNV Loss 21397061

Relevant External Links for FAM149A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM149A Gene

Disorders for FAM149A Gene

Relevant External Links for FAM149A

Genetic Association Database (GAD)

No disorders were found for FAM149A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM149A Gene

Publications for FAM149A Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PMID: 19460752) Yeung M.L. … Jeang K.T. (J. Biol. Chem. 2009) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM149A Gene

Sources for FAM149A Gene

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