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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAM13A Gene

protein-coding   GIFtS: 54
GCID: GC04M089647

Family With Sequence Similarity 13, Member A

(Previous names: family with sequence similarity 13, member A1)
(Previous symbol: FAM13A1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Family With Sequence Similarity 13, Member A1 2     ARHGAP482
FAM13A11 2 3 5     FAM13A1_v2 Protein2
Family With Sequence Similarity 13, Member A11 2     Protein FAM13A2
KIAA09143 5     

External Ids:    HGNC: 193671   Entrez Gene: 101442   Ensembl: ENSG000001386407   OMIM: 6132995   UniProtKB: O949883   

Export aliases for FAM13A gene to outside databases

Previous GC identifers: GC04M089866 GC04M085399


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FAM13A Gene: 
FAM13A (family with sequence similarity 13, member A) is a protein-coding gene. Diseases associated with FAM13A include chronic obstructive pulmonary disease, and kidney disease, and among its related super-pathways are Signaling by Rho GTPases and Signaling by GPCR. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is FAM13B.

Gene Wiki entry for FAM13A (Family with sequence similarity 13, member A1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM13A gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   HNF-3beta   Meis-1b   RORalpha1   Nkx3-1 v2   Nkx3-1 v3   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAM13A promoter sequence
   Search SABiosciences Chromatin IP Primers for FAM13A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM13A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q22.1   Ensembl cytogenetic band:  4q22.1   HGNC cytogenetic band: 4q22.1

FAM13A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM13A gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M089647:  view genomic region     (about GC identifiers)

Start:
89,647,106 bp from pter      End:
90,032,549 bp from pter
Size:
385,444 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FA13A_HUMAN, O94988 (See protein sequence)
Recommended Name: Protein FAM13A  
Size: 1023 amino acids; 116932 Da
Sequence caution: Sequence=BAA74937.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAC03636.1; Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: B4DLC1 Q24JP0 Q5PR21 Q8NBA3
Alternative splicing: 5 isoforms:  O94988-4   O94988-1   O94988-3   O94988-5   O94988-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM13A: NX_O94988

Explore proteomics data for FAM13A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O94988

  • FAM13A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FAM13A Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001015045.1  NP_001252507.1  NP_001252508.1  NP_001252509.1  NP_055698.2  

    ENSEMBL proteins: 
     ENSP00000378450   ENSP00000264344   ENSP00000427189   ENSP00000421914   ENSP00000421562  
     ENSP00000423252   ENSP00000427077   ENSP00000425784   ENSP00000423800   ENSP00000426517  
     ENSP00000422345   ENSP00000421269  
    Reactome Protein details: O94988
    Human Recombinant Protein Products for FAM13A: 
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    Novus Biologicals FAM13A Protein
    Novus Biologicals FAM13A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM13A 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--

    FAM13A for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for FAM13A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARHGAP: Rho GTPase activating proteins

    2 InterPro protein domains:
     IPR008936 Rho_GTPase_activation_prot
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry O94988

    ProtoNet protein and cluster: O94988

    UniProtKB/Swiss-Prot: FA13A_HUMAN, O94988
    Similarity: Belongs to the FAM13 family
    Similarity: Contains 1 Rho-GAP domain


    FAM13A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
         
    FAM13A for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FAM13A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAM13A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM13A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM13A 

    miRNA
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    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM13A (see all 61):
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    SwitchGear 3'UTR luciferase reporter plasmidFAM13A 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM13A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FAM13A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for FAM13A
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    FAM13A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM13A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/7 Interacting proteins for FAM13A (O949883 ENSP000002643444) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATF2P153363I2D: score=2 
    JUNP054123I2D: score=2 
    MEF2CQ064133I2D: score=2 
    RAPGEF2Q9Y4G83I2D: score=2 
    MAP3K10Q027793I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    FAM13A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAM13A (FA13A)

    Search CenterWatch for drugs/clinical trials and news about FAM13A / FA13A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAM13A gene (5 alternative transcripts): 
    NM_001015045.2  NM_001265578.1  NM_001265579.1  NM_001265580.1  NM_014883.3  

    Unigene Cluster for FAM13A:

    Family with sequence similarity 13, member A
    Hs.97270  [show with all ESTs]
    Unigene Representative Sequence: NM_014883
    18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000395002(uc003hsa.1 uc003hsb.1 uc003hsd.1 uc003hsc.1 uc011cdq.1 uc010ikr.1)
    ENST00000264344(uc011cdp.1 uc003hse.1 uc003hsf.1) ENST00000509478
    ENST00000511573 ENST00000503556 ENST00000511976 ENST00000508369 ENST00000513837
    ENST00000506433 ENST00000504229 ENST00000502811 ENST00000504836(uc003hsg.1)
    ENST00000508360 ENST00000511623 ENST00000507352 ENST00000515155 ENST00000502914
    ENST00000502459(uc003hsh.1)
    miRNA
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    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM13A (see all 61):
    hsa-miR-582-3p hsa-miR-607 hsa-miR-106a hsa-miR-485-3p hsa-miR-4305 hsa-miR-30d hsa-miR-301a hsa-miR-218
    SwitchGear 3'UTR luciferase reporter plasmidFAM13A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FAM13A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM13A
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM13A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM13A
    Sirion Biotech Customized lentivirus for stable overexpression of FAM13A 
                         Customized lentivirus expression plasmids for stable overexpression of FAM13A 
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    OriGene qSTAR qPCR primer pairs in human, mouse for FAM13A
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM13A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM13A

    Additional mRNA sequence: 

    AB020721.2 AF009202.1 AK027138.1 AK091328.1 AK091787.1 AK091881.1 AK123724.1 AK296932.1 
    AK298262.1 BC033006.1 BC041029.1 BC053569.1 BC058029.1 BC063126.1 BC086875.1 BX647410.1 

    24/27 DOTS entries (see all 27):

    DT.91852767  DT.100785857  DT.121257620  DT.91753707  DT.100020622  DT.95079716  DT.454578  DT.91753709 
    DT.121257545  DT.75135814  DT.100020547  DT.91750420  DT.101983381  DT.91721242  DT.100679264  DT.100735515 
    DT.99932895  DT.121257630  DT.121257618  DT.121257518  DT.121257629  DT.40218134  DT.40278706  DT.65286087 

    24/210 AceView cDNA sequences (see all 210):

    AA873757 CR615111 BC063126 AW613883 AB020721 CR610852 AW029578 F05350 
    BM787723 AA418884 D62906 F01608 BC033006 AW512166 BQ012433 BF195814 
    BP373366 CD677419 AI269099 AA324372 BQ014173 AI568115 Z41156 BU741924 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for FAM13A (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b · 9c · 9d ^ 10a · 10b · 10c ^ 11a ·
    SP1:                                                              -                 -     -     -                                                               
    SP2:                          -                                   -                 -     -     -                                                               
    SP3:                                                              -                 -     -     -                                                               
    SP4:                          -                                   -                 -                                                                           
    SP5:                                                              -     -           -     -     -                                                               

    ExUns: 11b ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b · 16c ^ 17a · 17b · 17c ^ 18a · 18b
    SP1:                                                                    -     -                           
    SP2:                                                                    -     -                           
    SP3:                                            -     -                 -     -                           
    SP4:                                            -     -                 -     -                           
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for FAM13A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAM13A expression in normal human tissues (normalized intensities)      FAM13A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTAGTCTGT
    FAM13A Expression
    About this image


    FAM13A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/10 selected tissues (see all 10) fully expand
     
     Blood Brain Barrier (Nervous System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Intestine (Gastrointestinal Tract)
             small intestine   
     
     Testis (Reproductive System)
             Sertoli cells Seminiferous Tubules

    See FAM13A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAM13A

    SOURCE GeneReport for Unigene cluster: Hs.97270

    UniProtKB/Swiss-Prot: FA13A_HUMAN, O94988
    Tissue specificity: Isoform 1 is widely expressed, with highest expression in skeletal muscle, thymus, brain and
    lung. Isoform 3 is less abundant than isoform 1 and predominantly expressed in kidney, pancreas,liver, lung and
    thymus

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM13A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FAM13A gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam13a1 , 5 family with sequence similarity 13, member A1, 5 83.09(n)1
    83.63(a)1
      6 (27.93 cM)5
    589091  NM_153574.21  NP_705802.11 
     589320905 
    chicken
    (Gallus gallus)
    Aves FAM13A1 family with sequence similarity 13, member A 74.41(n)
    77.39(a)
      422515  XM_420478.3  XP_420478.3 
    lizard
    (Anolis carolinensis)
    Reptilia FAM13A6
    Uncharacterized protein
    72(a)
    1 ↔ 1
    5(45888336-46040429)
    zebrafish
    (Danio rerio)
    Actinopterygii fam13a1 family with sequence similarity 13, member A 62.98(n)
    62.63(a)
      559330  XM_678637.3  XP_683729.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG64246
    --
    20(a)
    1 → many
    2R(13590840-13606832)


    ENSEMBL Gene Tree for FAM13A (if available)
    TreeFam Gene Tree for FAM13A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAM13A gene
    FAM13B2  FAM13C2  
    18/24 SIMAP similar genes for FAM13A using alignment to 9 protein entries:     FA13A_HUMAN (see all proteins) (see all similar genes):
    FAM13B    ARHGAP1    ARHGAP20    ARHGAP22    ARHGAP31    ABR
    ARHGAP25    ARHGAP32    ARHGAP8    KIAA0053    ARHGAP24    ARHGAP33
    SNX26    ARAP1    PRR5-ARHGAP8    CHN1    ARHGAP9    ARHGAP27

    FAM13A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6297 SNPs in FAM13A are shown (see all 6297)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30678071,2
    C--85613368(+) CTTAG-/GAA   
       
    /GGAA
    ATTGT
    2 -- int1 cds11NA 2
    rs672123881,2
    C--85628375(+) ACACA-/TAGTCTG 1 -- int11Minor allele frequency- TA:0.00NA 2
    rs567107051,2
    C--85698317(+) TTTTT-/T/TTT 
     TTTTTTT
    GAGAC
    1 -- int11NA 2
    rs1931957621,2
    --89651785(+) TAATCC/TACCCT 5 -- int10--------
    rs1428662011,2
    --89651823(+) CAGGCA/GTGAGC 5 -- int10--------
    rs1510725101,2
    --89651967(+) TTTTAC/TTTAGA 5 -- int10--------
    rs1409244841,2
    --89652111(+) CGGCCA/GCTTGG 5 -- int10--------
    rs76626801,2
    C,F--89652128(+) TCTAGC/TTTCTT 5 -- int13Minor allele frequency- T:0.22WA NA EA 358
    rs76874351,2
    C--89652146(+) AAGCGC/TTGGTG 5 -- int10--------
    rs1855482041,2
    --89652248(+) CATTAA/GTCTTG 5 -- int10--------

    HapMap Linkage Disequilibrium report for FAM13A (89647106 - 89897106 bp, first 250kb of FAM13A)

    Structural Variations
         Database of Genomic Variants (DGV) 10/20 variations for FAM13A (see all 20):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2647176CNV Deletion19546169
    esv2727954CNV Deletion23290073
    esv1054095CNV Deletion17803354
    esv2660897CNV Deletion23128226
    esv2669940CNV Deletion23128226
    esv1378129CNV Deletion17803354
    esv1010735CNV Deletion20482838
    esv2727955CNV Deletion23290073
    esv1980466CNV Deletion18987734
    esv2589450CNV Deletion19546169

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613299    OMIM disorders: --

    3 diseases for FAM13A:    About MalaCards
    chronic obstructive pulmonary disease    kidney disease    mental retardation

    1 disease from the University of Copenhagen DISEASES database for FAM13A:
    Chronic obstructive pulmonary disease

    FAM13A for disorders           About GeneDecksing

    Genetic Association Database (GAD): FAM13A
    Human Genome Epidemiology (HuGE) Navigator: FAM13A (8 documents)

    Export disorders for FAM13A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAM13A gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with FAM13A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A genome-wide association study of COPD identifies a s usceptibility locus on chromosome 19q13. (PubMed id 22080838)1, 4 Cho M.H.... . (2012)
    2. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Meta-analyses of genome-wide association studies iden tify multiple loci associated with pulmonary function. (PubMed id 20010835)1, 4 Hancock D.B....London S.J. (2010)
    5. Variants in FAM13A are associated with chronic obstru ctive pulmonary disease. (PubMed id 20173748)1, 4 Cho M.H....Silverman E.K. (2010)
    6. Genomewide association study of movement-related adve rse antipsychotic effects. (PubMed id 19875103)1, 4 Aberg K....van den Oord E.J. (2010)
    7. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    8. Loci Identified by Genome-wide Association Studies In fluence Different Disease-related Phenotypes in Chronic Obstructive Pulmonary D isease. (PubMed id 20656943)1, 4 Pillai S.G....Silverman E.K. (2010)
    9. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1, 4 Yoshida T....Yamada Y. (2009)
    10. Cloning and characterization of FAM13A1--a gene near a milk protein QTL on BTA6: evidence for population-wide linkage disequilibrium in Israeli Holsteins. (PubMed id 15234000)1, 2 Cohen M.... Seroussi E. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10144 HGNC: 19367 AceView: FAM13A1 Ensembl:ENSG00000138640 euGenes: HUgn10144
    ECgene: FAM13A H-InvDB: FAM13A

    (According to HUGE)
    About This Section
    HUGE: KIAA0914

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAM13A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FAM13A gene:
    Search GeneIP for patents involving FAM13A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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