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FAM135A Gene

protein-coding   GIFtS: 50
GCID: GC06P071122

Family With Sequence Similarity 135, Member A

(Previous name: KIAA1411)
(Previous symbol: KIAA1411)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 135, Member A1 2
KIAA14111 2 3
Protein FAM135A2

External Ids:    HGNC: 210841   Entrez Gene: 575792   Ensembl: ENSG000000822697   UniProtKB: Q9P2D63   

Export aliases for FAM135A gene to outside databases

Previous GC identifers: GC06P071179 GC06P068321


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM135A Gene:
FAM135A (family with sequence similarity 135, member A) is a protein-coding gene. An important paralog of this gene is FAM135B.

Gene Wiki entry for FAM135A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM135A gene promoter:
         STAT1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU6F1 (c2)   POU3F2   SRY   STAT2   STAT3   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM135A promoter sequence
   Search Chromatin IP Primers for FAM135A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM135A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q13   Ensembl cytogenetic band:  6q13   HGNC cytogenetic band: 6q13

FAM135A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM135A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P071122:  view genomic region     (about GC identifiers)

Start:
71,122,644 bp from pter      End:
71,270,877 bp from pter
Size:
148,234 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: F135A_HUMAN, Q9P2D6 (See protein sequence)
Recommended Name: Protein FAM135A  
Size: 1515 amino acids; 169840 Da
Sequence caution: Sequence=AAH65767.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BAA90995.1;
Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BAA92649.1; Type=Erroneous initiation;
Sequence=CAB66754.1; Type=Erroneous initiation; Sequence=CAI42417.1; Type=Erroneous gene model prediction;
Secondary accessions: A2RRQ5 Q3C0H3 Q5JXK0 Q5JXK1 Q68DW0 Q6P081 Q9H0F2 Q9NU48 Q9NUQ5 Q9NXL5
Alternative splicing: 4 isoforms:  Q9P2D6-1   Q9P2D6-2   Q9P2D6-3   Q9P2D6-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM135A: NX_Q9P2D6

Explore proteomics data for FAM135A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM135A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001099001.1  NP_001156001.1  NP_065870.3  

    ENSEMBL proteins: 
     ENSP00000410768   ENSP00000423785   ENSP00000422406   ENSP00000421505   ENSP00000425101  
     ENSP00000409201   ENSP00000354913   ENSP00000194672   ENSP00000423307   ENSP00000359510  

    FAM135A Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for FAM135A

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR007751 DUF676_lipase-like
     IPR022122 DUF3657

    Graphical View of Domain Structure for InterPro Entry Q9P2D6

    ProtoNet protein and cluster: Q9P2D6

    UniProtKB/Swiss-Prot: F135A_HUMAN, Q9P2D6
    Similarity: Belongs to the FAM135 family


    Find genes that share domains with FAM135A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008374O-acyltransferase activity ----
    GO:0016788hydrolase activity, acting on ester bonds ----
         
    Find genes that share ontologies with FAM135A           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FAM135A:
     Decreased influenza A/WSN/33 r 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM135A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM135A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM135A

    miRNA
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    miRTarBase miRNAs that target FAM135A:
    hsa-mir-92a-3p (MIRT049264), hsa-let-7d-5p (MIRT032108), hsa-mir-26b-5p (MIRT030246), hsa-mir-155-5p (MIRT021063), hsa-mir-335-5p (MIRT019033)

    Block miRNA regulation of human, mouse, rat FAM135A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM135A (see all 52):
    hsa-miR-21* hsa-miR-323-3p hsa-miR-548j hsa-let-7d hsa-miR-15a hsa-miR-503 hsa-miR-25 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidFAM135A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM135A

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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM135A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM135A

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    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM135A 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM135A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM135A
    Interactions:

        Search GeneGlobe Interaction Network for FAM135A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for FAM135A (Q9P2D62, 3 ENSP000001946724) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCBD1P614573I2D: score=1 
    UTP18ENSP000002252984STRING: ENSP00000225298
    AATFENSP000002254024STRING: ENSP00000225402
    SLC27A1ENSP000002525954STRING: ENSP00000252595
    SLC27A2ENSP000002678424STRING: ENSP00000267842
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006505GPI anchor metabolic process ----
    GO:0006629lipid metabolic process ----
    GO:0006886intracellular protein transport ----

    Find genes that share ontologies with FAM135A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM135A (F135A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM135A gene (3 alternative transcripts): 
    NM_001105531.2  NM_001162529.1  NM_020819.4  

    Unigene Cluster for FAM135A:

    Family with sequence similarity 135, member A
    Hs.211700  [show with all ESTs]
    Unigene Representative Sequence: NM_001162529
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514185 ENST00000418814(uc003pfi.3 uc003pfj.3 uc003pfn.3 uc010kan.2)
    ENST00000505769 ENST00000515323 ENST00000508844 ENST00000515280 ENST00000507085
    ENST00000457062 ENST00000361499 ENST00000194672(uc003pfl.3) ENST00000505868(uc003pfo.1)
    ENST00000393299(uc003pfk.3) ENST00000425415(uc003pfm.1) ENST00000507049
    ENST00000505675(uc003pfp.3) ENST00000370479(uc003pfh.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat FAM135A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM135A (see all 52):
    hsa-miR-21* hsa-miR-323-3p hsa-miR-548j hsa-let-7d hsa-miR-15a hsa-miR-503 hsa-miR-25 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidFAM135A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM135A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM135A
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    OriGene clones in human, mouse for FAM135A (see all 18)
    OriGene ORF clones in mouse, rat for FAM135A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): FAM135A (NM_020819)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM135A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM135A
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for FAM135A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM135A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM135A
      QuantiFast Probe-based Assays in human, mouse, rat FAM135A

    Additional mRNA sequence: 

    AB037832.1 AJ420590.1 AK000183.1 AK001911.1 AK002067.1 AK023639.2 AK128547.1 AK225230.1 
    AL136820.1 BC030797.1 BC065767.1 BC131782.1 CR749254.1 

    15 DOTS entries:

    DT.409200  DT.121389394  DT.102825397  DT.100752259  DT.91743328  DT.95367685  DT.92067539  DT.40270649 
    DT.40306706  DT.91988973  DT.40202562  DT.92412760  DT.97822260  DT.121389386  DT.97812874 

    Selected AceView cDNA sequences (see all 89):

    AB037832 BM789688 AL704083 BC065767 CK903384 BQ721634 BX494830 BQ024339 
    AA314195 BC030797 T16333 AL699036 AK001911 AL043412 BM461890 BX484049 
    BX480918 CK903383 BM801396 AJ420590 AU136559 BU686042 AK128547 CD644029 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM135A (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20a · 20b ^ 21a ·
    SP1:                                                              -                 -                                                           -               
    SP2:                                      -                                         -                 -                                         -               
    SP3:                                                                                -                                                                           
    SP4:                                                                                                                                            -               
    SP5:                                                                                                                                            -           -   

    ExUns: 21b ^ 22a · 22b ^ 23a · 23b
    SP1:        -                     
    SP2:        -                     
    SP3:                              
    SP4:        -                     
    SP5:  -     -                     


    ECgene alternative splicing isoforms for FAM135A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM135A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FAM135A Expression
    About this image


    FAM135A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    FAM135A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM135A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.211700

    UniProtKB/Swiss-Prot: F135A_HUMAN, Q9P2D6
    Tissue specificity: Ubiquitous

        Custom PCR Arrays for FAM135A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM135A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM135A gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam135a1 , 5 family with sequence similarity 135, member A1, 5 87.39(n)1
    84.37(a)1
      1 (9.87 cM)5
    681871  NM_026604.41  NP_080880.41 
     240107585 
    chicken
    (Gallus gallus)
    Aves FAM135A1 family with sequence similarity 135, member A 75.69(n)
    72.46(a)
      421871  XM_419888.4  XP_419888.2 
    lizard
    (Anolis carolinensis)
    Reptilia FAM135A6
    family with sequence similarity 135, member A
    64(a)
    1 ↔ 1
    1(167592416-167660958)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC041740.12   -- 78.8(n)    BC041740.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5664351 novel protein similar to H.sapiens FAM135A, family more 62.32(n)
    62.75(a)
      566435  NM_001145594.1  NP_001139066.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG323336
    --
    30(a)
    1 → many
    3L(1275956-1295699)
    worm
    (Caenorhabditis elegans)
    Secernentea C09D4.41 C09D4.4 45.38(n)
    30(a)
      172200  NM_059206.2  NP_491607.2 


    ENSEMBL Gene Tree for FAM135A (if available)
    TreeFam Gene Tree for FAM135A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM135A gene
    FAM135B2  
    1 SIMAP similar gene for FAM135A using alignment to 6 protein entries:     F135A_HUMAN (see all proteins):
    FAM135B

    Find genes that share paralogs with FAM135A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM135A (see all 2761)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1997074691,2
    C--71121249(-) TTGGGA/GGGAGT 2 -- us2k10--------
    rs1451028221,2
    --71121360(+) TCTGAA/GCTTCA 2 -- us2k10--------
    rs1389868341,2
    --71121515(+) TGTGAA/TTTGAA 2 -- us2k10--------
    rs1844940441,2
    --71121579(+) TGCACA/GGACGT 2 -- us2k10--------
    rs69127161,2
    C,F,H--71121612(+) TTACTA/GTATTT 2 -- us2k115Minor allele frequency- G:0.08NS EA NA WA CSA 1752
    rs624203221,2
    F--71121613(+) TACTAC/TATTTT 2 -- us2k11Minor allele frequency- T:0.50NA 2
    rs58772531,2
    C--71121638(+) AAAAA-/ACAGAA 2 -- us2k1 tfbs3 trp30--------
    rs69324701,2
    C,F--71121673(+) TTTGAG/AGCTAA 2 -- us2k1 tfbs35Minor allele frequency- A:0.18NA WA EA 362
    rs1868279361,2
    --71121787(+) ATTCAC/TACAAA 2 -- us2k10--------
    rs1917082951,2
    --71121854(+) AAGCCA/GGGCAC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for FAM135A (71122644 - 71270877 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for FAM135A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv886146CNV Loss21882294
    nsv886145CNV Loss21882294
    nsv886144CNV Gain21882294
    nsv524328CNV Gain19592680
    nsv886142CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with FAM135A           About GenesLikeMe

    Genetic Association Database (GAD): FAM135A
    Human Genome Epidemiology (HuGE) Navigator: FAM135A (3 documents)

    Export disorders for FAM135A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM135A gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with FAM135A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Genome-wide searching of rare genetic variants in WTCCC data. (PubMed id 20549515)1, 4 Feng T. and Zhu X. (Hum. Genet. 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    6. Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants. (PubMed id 20970119)1 Malki K....Schalkwyk L.C. (Biol. Psychiatry 2011)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Exclusion of four candidate genes, KHDRBS2, PTP4A1, KIAA1411 and OGFRL1, as causative of autosomal recessive retinitis pigmentosa. (PubMed id 16192744)2 Abd El-Aziz M.M.... Bhattacharya S.S. (Ophthalmic Res. 2006)
    10. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57579 HGNC: 21084 AceView: KIAA1411 Ensembl:ENSG00000082269 euGenes: HUgn57579
    ECgene: FAM135A H-InvDB: FAM135A

    (According to HUGE)
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    HUGE: KIAA1411

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM135A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM135A gene:
    Search GeneIP for patents involving FAM135A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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