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Aliases for FAM134C Gene

Aliases for FAM134C Gene

  • Family With Sequence Similarity 134, Member C 2 3

External Ids for FAM134C Gene

Previous GeneCards Identifiers for FAM134C Gene

  • GC17M037986
  • GC17M040731
  • GC17M036496

Summaries for FAM134C Gene

GeneCards Summary for FAM134C Gene

FAM134C (Family With Sequence Similarity 134, Member C) is a Protein Coding gene. An important paralog of this gene is FAM134A.

Gene Wiki entry for FAM134C Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM134C Gene

Genomics for FAM134C Gene

Regulatory Elements for FAM134C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM134C Gene

42,579,508 bp from pter
42,610,623 bp from pter
31,116 bases
Minus strand

Genomic View for FAM134C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM134C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM134C Gene

Proteins for FAM134C Gene

  • Protein details for FAM134C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM134C
    Protein Accession:
    Secondary Accessions:
    • B3KR75

    Protein attributes for FAM134C Gene

    466 amino acids
    Molecular mass:
    51396 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM134C Gene


neXtProt entry for FAM134C Gene

Proteomics data for FAM134C Gene at MOPED

Post-translational modifications for FAM134C Gene

  • Ubiquitination at Lys115
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for FAM134C Gene

Domains for FAM134C Gene

Protein Domains for FAM134C Gene


Suggested Antigen Peptide Sequences for FAM134C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q86VR2
  • Belongs to the FAM134 family.
genes like me logo Genes that share domains with FAM134C: view

No data available for Gene Families for FAM134C Gene

Function for FAM134C Gene

Gene Ontology (GO) - Molecular Function for FAM134C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM134C: view
genes like me logo Genes that share phenotypes with FAM134C: view

Animal Model Products

CRISPR Products

miRNA for FAM134C Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM134C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM134C Gene

Localization for FAM134C Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM134C Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FAM134C Gene COMPARTMENTS Subcellular localization image for FAM134C gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM134C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM134C: view

Pathways for FAM134C Gene

SuperPathways for FAM134C Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM134C Gene


No data available for Pathways by source for FAM134C Gene

Transcripts for FAM134C Gene

Unigene Clusters for FAM134C Gene

Family with sequence similarity 134, member C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM134C

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM134C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM134C Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11
SP1: - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - - -
SP5: - -
SP6: - - - - - - -
SP8: - - -
SP9: - -

Relevant External Links for FAM134C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM134C Gene

mRNA expression in normal human tissues for FAM134C Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM134C Gene

SOURCE GeneReport for Unigene cluster for FAM134C Gene Hs.632262

genes like me logo Genes that share expressions with FAM134C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM134C Gene

Orthologs for FAM134C Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM134C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM134C 35
  • 99.86 (n)
  • 99.79 (a)
FAM134C 36
  • 100 (a)
(Bos Taurus)
Mammalia FAM134C 35
  • 91.13 (n)
  • 93.56 (a)
FAM134C 36
  • 94 (a)
(Canis familiaris)
Mammalia FAM134C 35
  • 92.27 (n)
  • 92.92 (a)
FAM134C 36
  • 93 (a)
(Mus musculus)
Mammalia Fam134c 35
  • 90.34 (n)
  • 91.2 (a)
Fam134c 16
Fam134c 36
  • 91 (a)
(Monodelphis domestica)
Mammalia FAM134C 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia FAM134C 36
  • 61 (a)
(Rattus norvegicus)
Mammalia Fam134c 35
  • 90.49 (n)
  • 90.99 (a)
(Gallus gallus)
Aves FAM134C 35
  • 70.34 (n)
  • 70.49 (a)
FAM134C 36
  • 68 (a)
(Anolis carolinensis)
Reptilia FAM134C 36
  • 62 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.30959 35
tropical clawed frog
(Silurana tropicalis)
Amphibia fam134c 35
  • 66.04 (n)
  • 66.82 (a)
Str.6330 35
(Danio rerio)
Actinopterygii fam134c 35
  • 61.19 (n)
  • 57.53 (a)
fam134c 36
  • 48 (a)
Species with no ortholog for FAM134C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM134C Gene

Gene Tree for FAM134C (if available)
Gene Tree for FAM134C (if available)

Paralogs for FAM134C Gene

Paralogs for FAM134C Gene

Selected SIMAP similar genes for FAM134C Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with FAM134C: view

Variants for FAM134C Gene

Sequence variations from dbSNP and Humsavar for FAM134C Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs492425 -- 42,597,917(-) cgcgg(G/T)ggctt intron-variant
rs626882 -- 42,597,940(+) ACGTT(A/T)TTTTA intron-variant
rs1504154 -- 42,599,344(+) GGTGG(C/T)AGGCT intron-variant
rs1517002 -- 42,583,451(-) TAGCT(A/C)CCTTT intron-variant
rs2138643 -- 42,602,775(+) tgttt(C/T)tacga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM134C Gene

Variant ID Type Subtype PubMed ID
dgv3172n71 CNV Loss 21882294
esv33998 OTHER Inversion 15654335

Relevant External Links for FAM134C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM134C Gene

Disorders for FAM134C Gene

No disorders were found for FAM134C Gene.

No data available for UniProtKB/Swiss-Prot for FAM134C Gene

Publications for FAM134C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for FAM134C Gene

  • antibodies-online peptides for FAM134C
  • antibodies-online antibodies for FAM134C
  • antibodies-online kits for FAM134C

Sources for FAM134C Gene

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