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Aliases for FAM134A Gene

Aliases for FAM134A Gene

  • Family With Sequence Similarity 134, Member A 2 3
  • C2orf17 3 4
  • Chromosome 2 Open Reading Frame 17 2
  • Protein FAM134A 3

External Ids for FAM134A Gene

Previous Symbols for FAM134A Gene

  • C2orf17

Summaries for FAM134A Gene

GeneCards Summary for FAM134A Gene

FAM134A (Family With Sequence Similarity 134, Member A) is a Protein Coding gene. An important paralog of this gene is FAM134C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM134A Gene

Genomics for FAM134A Gene

Genomic Location for FAM134A Gene

Start:
219,176,225 bp from pter
End:
219,185,479 bp from pter
Size:
9,255 bases
Orientation:
Plus strand

Genomic View for FAM134A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM134A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM134A Gene

Regulatory Elements for FAM134A Gene

Proteins for FAM134A Gene

  • Protein details for FAM134A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NC44-F134A_HUMAN
    Recommended name:
    Protein FAM134A
    Protein Accession:
    Q8NC44
    Secondary Accessions:
    • Q6P1P5
    • Q9H0K7

    Protein attributes for FAM134A Gene

    Size:
    543 amino acids
    Molecular mass:
    57830 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM134A Gene

Proteomics data for FAM134A Gene at MOPED

Post-translational modifications for FAM134A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM134A Gene

Domains for FAM134A Gene

Protein Domains for FAM134A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F134A_HUMAN
Family:
  • Belongs to the FAM134 family.:
    • Q8NC44
genes like me logo Genes that share domains with FAM134A: view

No data available for Gene Families for FAM134A Gene

Function for FAM134A Gene

Phenotypes for FAM134A Gene

GenomeRNAi human phenotypes for FAM134A:
genes like me logo Genes that share phenotypes with FAM134A: view

miRNA for FAM134A Gene

miRTarBase miRNAs that target FAM134A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM134A Gene

Localization for FAM134A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM134A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM134A Gene COMPARTMENTS Subcellular localization image for FAM134A gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 2
extracellular 2
cytoskeleton 1
cytosol 1

Gene Ontology (GO) - Cellular Components for FAM134A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM134A: view

Pathways for FAM134A Gene

SuperPathways for FAM134A Gene

No Data Available

Interacting Proteins for FAM134A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000395249%0d%0a9606.ENSP00000363970%0d%0a
Selected Interacting proteins: Q8NC44-F134A_HUMAN ENSP00000395249 for FAM134A Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for FAM134A Gene

None

No data available for Pathways by source for FAM134A Gene

Transcripts for FAM134A Gene

Unigene Clusters for FAM134A Gene

Family with sequence similarity 134, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM134A Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10
SP1:
SP2: -
SP3: -
SP4: - - - - -
SP5:
SP6:

Relevant External Links for FAM134A Gene

GeneLoc Exon Structure for
FAM134A
ECgene alternative splicing isoforms for
FAM134A

Expression for FAM134A Gene

mRNA expression in normal human tissues for FAM134A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM134A Gene

SOURCE GeneReport for Unigene cluster for FAM134A Gene Hs.516707

genes like me logo Genes that share expressions with FAM134A: view

Orthologs for FAM134A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM134A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM134A 36
  • 99.51 (n)
  • 99.45 (a)
FAM134A 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C2ORF17 37
  • 89 (a)
OneToOne
FAM134A 36
  • 90.49 (n)
  • 91.9 (a)
dog
(Canis familiaris)
Mammalia FAM134A 36
  • 89.62 (n)
  • 90.91 (a)
FAM134A 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam134a 36
  • 87.69 (n)
  • 87.83 (a)
Fam134a 16
Fam134a 37
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM134A 37
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 31 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Fam134a 36
  • 88.64 (n)
  • 89.66 (a)
chicken
(Gallus gallus)
Aves FAM134A 36
  • 67.43 (n)
  • 67.09 (a)
FAM134A 37
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM134A 37
  • 52 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.13426 36
tropical clawed frog
(Silurana tropicalis)
Amphibia fam134a 36
  • 61.87 (n)
  • 59.23 (a)
Str.17191 36
zebrafish
(Danio rerio)
Actinopterygii fam134a 36
  • 61.88 (n)
  • 59.23 (a)
fam134a 37
  • 45 (a)
OneToOne
Species with no ortholog for FAM134A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM134A Gene

ENSEMBL:
Gene Tree for FAM134A (if available)
TreeFam:
Gene Tree for FAM134A (if available)

Paralogs for FAM134A Gene

Paralogs for FAM134A Gene

Selected SIMAP similar genes for FAM134A Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with FAM134A: view

Variants for FAM134A Gene

Sequence variations from dbSNP and Humsavar for FAM134A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs7017 -- 219,183,428(+) AGGGT(C/T)AGGAA utr-variant-3-prime
rs1139920 -- 219,183,063(+) TTCTG(C/T)GTTCC utr-variant-3-prime
rs1139921 -- 219,183,079(+) GCTTT(A/G)TTTCC utr-variant-3-prime
rs1139922 -- 219,183,081(+) TTTAT(G/T)TCCCT utr-variant-3-prime
rs2272017 -- 219,181,627(+) TCCTG(C/G)TTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM134A Gene

Variant ID Type Subtype PubMed ID
nsv875868 CNV Gain 21882294
nsv508200 CNV Loss 20534489
nsv875869 CNV Loss 21882294
nsv3170 CNV Loss 18451855

Relevant External Links for FAM134A Gene

HapMap Linkage Disequilibrium report
FAM134A

Disorders for FAM134A Gene

No disorders were found for FAM134A Gene.

No data available for UniProtKB/Swiss-Prot for FAM134A Gene

Publications for FAM134A Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM134A Gene

  • antibodies-online peptides for FAM134A
  • antibodies-online antibodies for FAM134A
  • antibodies-online kits for FAM134A

Sources for FAM134A Gene

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