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Aliases for FAM133A Gene

Aliases for FAM133A Gene

  • Family With Sequence Similarity 133, Member A 2 3
  • Cancer/Testis Antigen 115 2 3
  • CT115 3

External Ids for FAM133A Gene

Previous GeneCards Identifiers for FAM133A Gene

  • GC0XP092815
  • GC0XP092929
  • GC0XP082751

Summaries for FAM133A Gene

GeneCards Summary for FAM133A Gene

FAM133A (Family With Sequence Similarity 133, Member A) is a Protein Coding gene. An important paralog of this gene is FAM133B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM133A Gene

Genomics for FAM133A Gene

Regulatory Elements for FAM133A Gene

Genomic Location for FAM133A Gene

93,673,736 bp from pter
93,712,274 bp from pter
38,539 bases
Plus strand

Genomic View for FAM133A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM133A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM133A Gene

Proteins for FAM133A Gene

  • Protein details for FAM133A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM133A
    Protein Accession:

    Protein attributes for FAM133A Gene

    248 amino acids
    Molecular mass:
    28941 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM133A Gene

Proteomics data for FAM133A Gene at MOPED

Post-translational modifications for FAM133A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM133A Gene

No data available for DME Specific Peptides for FAM133A Gene

Domains & Families for FAM133A Gene

Protein Domains for FAM133A Gene


Suggested Antigen Peptide Sequences for FAM133A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM133 family.
  • Belongs to the FAM133 family.
genes like me logo Genes that share domains with FAM133A: view

No data available for Gene Families for FAM133A Gene

Function for FAM133A Gene

Gene Ontology (GO) - Molecular Function for FAM133A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM133A: view

Phenotypes for FAM133A Gene

genes like me logo Genes that share phenotypes with FAM133A: view

Animal Model Products

CRISPR Products

miRNA for FAM133A Gene

miRTarBase miRNAs that target FAM133A

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM133A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM133A Gene

Localization for FAM133A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM133A Gene

Pathways & Interactions for FAM133A Gene

SuperPathways for FAM133A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM133A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM133A Gene

Drugs & Compounds for FAM133A Gene

No Compound Related Data Available

Transcripts for FAM133A Gene

mRNA/cDNA for FAM133A Gene

Unigene Clusters for FAM133A Gene

Family with sequence similarity 133, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM133A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM133A Gene

No ASD Table

Relevant External Links for FAM133A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM133A Gene

mRNA expression in normal human tissues for FAM133A Gene

mRNA differential expression in normal tissues according to GTEx for FAM133A Gene

This gene is overexpressed in Testis (x6.1), Brain - Hypothalamus (x4.5), and Brain - Nucleus accumbens (basal ganglia) (x4.4).

Protein differential expression in normal tissues from HIPED for FAM133A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (41.8) and Heart (24.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM133A Gene

SOURCE GeneReport for Unigene cluster for FAM133A Gene Hs.110069

genes like me logo Genes that share expression patterns with FAM133A: view

Protein tissue co-expression partners for FAM133A Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM133A Gene

Orthologs for FAM133A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM133A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM133A 35
  • 86.21 (n)
  • 82.27 (a)
FAM133A 36
  • 90 (a)
(Canis familiaris)
Mammalia FAM133A 35
  • 86.61 (n)
  • 89.04 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 66 (a)
(Gallus gallus)
Aves FAM133B 36
  • 70 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 69 (a)
(Danio rerio)
Actinopterygii fam133b 36
  • 58 (a)
Species with no ortholog for FAM133A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM133A Gene

Gene Tree for FAM133A (if available)
Gene Tree for FAM133A (if available)

Paralogs for FAM133A Gene

Paralogs for FAM133A Gene

(2) SIMAP similar genes for FAM133A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM133A: view

Variants for FAM133A Gene

Sequence variations from dbSNP and Humsavar for FAM133A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs967299 -- 93,712,554(-) TCAAC(A/G)GAATA downstream-variant-500B
rs980981 -- 93,692,149(-) gaatc(A/G)gtaag intron-variant
rs1053564 -- 93,709,422(+) ACCAT(G/T)GGGAA reference, missense
rs1123623 -- 93,691,719(+) gggtt(A/G)gattt intron-variant
rs1543865 -- 93,712,705(-) AGTGT(A/G)TTATC downstream-variant-500B

Variation tolerance for FAM133A Gene

Residual Variation Intolerance Score: 61.54% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.40; 42.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM133A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM133A Gene

Disorders for FAM133A Gene

Relevant External Links for FAM133A

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM133A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM133A Gene

Publications for FAM133A Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  2. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for FAM133A Gene

Sources for FAM133A Gene

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