FAM133A Gene
protein-coding GIFtS: 39
GCID: GC0XP092929
|
|
family with sequence similarity 133, member A
| |
Aliases
for FAM133A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 133, Member A1 2 | | CT1151 2 | | FLJ376591 | | RP1-32F7.21 | | Cancer/Testis Antigen 1152 | | Protein FAM133A2 |
Export aliases for FAM133A gene to outside databasesPrevious GC identifers: GC0XP092815 GC0XP082751 |
Summaries
for FAM133A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM133A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM133A gene promoter:
TBP Bach1 GCNF STAT5A GATA-1 IRF-2 GCNF-1 GCNF-2 RSRFC4 ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM133A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM133A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq21.32 Ensembl cytogenetic band: Xq21.32 HGNC cytogenetic band: Xq21.32FAM133A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP092929: view genomic region
(about GC identifiers)
Start:
|
92,929,012 bp from pter |
End:
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92,967,273 bp from pter |
Size:
|
38,262 bases |
Orientation:
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plus strand |
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Proteins
for FAM133A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F133A_HUMAN, Q8N9E0 (See
protein sequence)Recommended Name: Protein FAM133A Size: 248 amino acids; 28941 DaExplore the universe of human proteins at neXtProt for FAM133A: NX_Q8N9E0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N9E0
FAM133A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001164580.1 NP_001164581.1 NP_001164582.1 NP_775969.1
ENSEMBL proteins: ENSP00000362169 ENSP00000441389 ENSP00000348067 ENSP00000318974
Human Recombinant Protein Products for FAM133A:
FAM133A Antibody Products:
Assay Products for FAM133A: |
Protein
Domains /
Families
for FAM133A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM133A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N9E0ProtoNet protein and cluster: Q8N9E0 UniProtKB/Swiss-Prot: F133A_HUMAN, Q8N9E0Similarity: Belongs to the FAM133 family |
Function
for FAM133A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for FAM133A:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM133A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM133A (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for FAM133A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM133A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM133A |
|
Pathways & Interactions
for FAM133A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM133A
|
Drugs & Compounds
for FAM133A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM133A
Search CenterWatch for drugs/clinical trials and news about FAM133A / F133A
|
Transcripts
for FAM133A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM133A gene (4 alternative transcripts): NM_001171109.1 NM_001171110.1 NM_001171111.1 NM_173698.2 Unigene Cluster for FAM133A: Family with sequence similarity 133, member A Hs.110069 [show with all ESTs]Unigene Representative Sequence: NM_0011711104 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000332647 ENST00000538690(uc022bzu.1) ENST00000355813(uc004efr.2 uc022bzv.1)
ENST00000322139(uc022bzw.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM133A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM133A (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): FAM133A (NM_173698) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM133A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM133A |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM133A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM133A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM133A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM133A |
Additional cDNA sequence: AK094978.1 BC113385.1 BC113387.1 4 DOTS entries: DT.206553 DT.100747128 DT.121298687 DT.121298737 24/28 AceView cDNA sequences (see all 28): W92969 AK094978 W78711 AI655800 BU194152 AI962308 NM_173698 BQ438275 AI339405 AI127575 BX095621 W92970 W80479 AI653208 AA609774 AI864183 AA909330 AW236582 BF968643 BX092755 AA625803 BE073134 AW629391 BE073127
GeneLoc Exon Structure
|
Expression
for FAM133A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM133A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGACCTGAA
About this image
See FAM133A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM133A
SOURCE GeneReport for Unigene cluster: Hs.110069
SABiosciences Custom PCR Arrays for FAM133A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM133A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM133A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM133A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM133A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM133A |
Orthologs
for FAM133A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM133A gene from 6/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC4205576 |
hypothetical protein LOC420557 |
73(a) |
1 → many |
2(22635559-22649971) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
69(a) |
1 → many |
6(21302197-21313657) |
zebrafish
(Danio rerio) |
Actinopterygii |
fam133b6 |
family with sequence similarity 133, member B |
57(a) |
1 → many |
19(41295613-41308285) |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
7(a) |
possible ortholog |
GroupUn.213(12601-14211) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G598006AT2G437956 |
uncharacterized protein |
17(a)13(a) |
many ↔ manymany ↔ many |
3(22094437-22096358) 2(18140944-18142369) |
rice
(Oryza sativa) |
Liliopsida |
-- |
protein FAM133, putative, expressed |
20(a) |
1 → many |
4(24656164-24658572) |
Species with no ortholog for FAM133A
ENSEMBL Gene Tree for FAM133A (if available)
TreeFam Gene Tree for FAM133A (if available) |
Paralogs
for FAM133A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM133A gene
- FAM133B2 CIR12
2 SIMAP similar genes for FAM133A using alignment to 1 protein entry: F133A_HUMAN:MGC40405 FAM133B
FAM133A for paralogs About GeneDecksing
5/6 Pseudogenes.org Pseudogenes for FAM133A (see all 6)
PGOHUM00000238809 PGOHUM00000239375 PGOHUM00000244464 PGOHUM00000259731 PGOHUM00000240399
|
Genomic Variants
for FAM133A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM133A (92929012 - 92967273 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM133A: --
Locus Specific Mutation Databases (LSDB): FAM133A
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM133A |
|
Disorders
/ Diseases
for FAM133A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM133A for disorders About GeneDecksing
1  disease for FAM133A: About MalaCardsmalaria
Export disorders for FAM133A gene to outside databases
|
Publications
for FAM133A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM133A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM133A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM133A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM133A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM133A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM133A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM133A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM133A gene:
Search GeneIP for patents involving FAM133A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM133A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM133A | | | OriGene Protein Over-expression Lysate for FAM133A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM133A | | OriGene 3'-UTR Clone for FAM133A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM133A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM133A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM133A |
| |  |  |  |  | | | | |
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 |
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 | | | FAM133A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM133A |
|  |  |  |  | | | | Search ThermoFisher Antibodies for FAM133A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM133A |
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