FAM132B Gene
protein-coding GIFtS: 34
GCID: GC02P239067 (predicted)
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family with sequence similarity 132, member B
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Aliases
for FAM132B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 132, Member B1 2 | | C1QTNF151 2 | | CTRP151 2 | | FLJ370341 | | Myonectin1 | | Protein FAM132B2 |
Export aliases for FAM132B gene to outside databasesPrevious GC identifers: GC02P238732 GC02P230863 |
Summaries
for FAM132B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM132B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NT_005120.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM132B gene promoter:
C/EBPbeta NF-kappaB MZF-1 PPAR-alpha NF-kappaB2 COMP1 STAT3 Pax-4a NF-kappaB1 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM132B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM132B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q37.3 Ensembl cytogenetic band: 2q37.3 HGNC cytogenetic band: 2q37.3FAM132B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P239067: view genomic region
(about GC identifiers)
Start:
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239,067,623 bp from pter |
End:
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239,077,541 bp from pter |
Size:
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9,919 bases |
Orientation:
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plus strand |
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Proteins
for FAM132B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F132B_HUMAN, Q4G0M1 (See
protein sequence)Recommended Name: Protein FAM132B precursor Size: 354 amino acids; 37279 Da
Subcellular location: Secreted (Potential)Explore the universe of human proteins at neXtProt for FAM132B: NX_Q4G0M1
FAM132B Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000442304 ENSP00000343261 ENSP00000349855
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
-- | -- | | GO:0005615 | extracellular space |
IEA | -- |
FAM132B for ontologies About GeneDecksing
FAM132B Antibody Products:
Assay Products for FAM132B: |
Protein
Domains /
Families
for FAM132B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM132B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q4G0M1ProtoNet protein and cluster: Q4G0M1 UniProtKB/Swiss-Prot: F132B_HUMAN, Q4G0M1Similarity: Belongs to the FAM132 family |
Function
for FAM132B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM132B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0042803 | protein homodimerization activity |
IEA | -- |
FAM132B for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Fam132btm1Lex for FAM132B
1 MGI phenotypic allele  for Fam132b (no phenotypes)
FAM132B for phenotypes About GeneDecksing
|
Pathways & Interactions
for FAM132B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM132B
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019217 | regulation of fatty acid metabolic process |
IEA | -- | | GO:2000193 | positive regulation of fatty acid transport |
IEA | -- |
FAM132B for ontologies About GeneDecksing
|
Drugs & Compounds
for FAM132B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM132B
Search CenterWatch for drugs/clinical trials and news about FAM132B / F132B 
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Transcripts
for FAM132B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Clusters for FAM132B: Family with sequence similarity 132, member B Hs.24951 [show with all ESTs], Hs.742300 [show with all ESTs]Unigene Representative Sequences: BC047423, AK0943537 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000486834 ENST00000546354 ENST00000481917 ENST00000473274(uc002vxt.3)
ENST00000479091 ENST00000344233 ENST00000357303(uc002vxu.3)
Additional cDNA sequence: AK094353.1 4 DOTS entries: DT.100748891 DT.100748889 DT.95193765 DT.100748890
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for FAM132B About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 |
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| SP1: | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | |
ECgene alternative splicing isoforms for FAM132B
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Expression
for FAM132B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM132B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGACACACA
About this image
Genevestigator expression for FAM132B
SOURCE GeneReport for Unigene clusters: Hs.24951 Hs.742300
SABiosciences Custom PCR Arrays for FAM132B
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM132B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM132B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM132B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM132B |
Orthologs
for FAM132B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM132B gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
FAM132B6 |
-- |
48(a) |
1 ↔ 1 |
3(35362782-35371547) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch1073-184j22.16 |
si:ch1073-184j22.1 |
37(a) |
1 ↔ 1 |
2(5005145-5032086) |
ENSEMBL Gene Tree for FAM132B (if available)
TreeFam Gene Tree for FAM132B (if available) |
Paralogs
for FAM132B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM132B gene
- FAM132A2
1 SIMAP similar gene for FAM132B using alignment to 3 protein entries: F132B_HUMAN (see all proteins):FAM132A
FAM132B for paralogs About GeneDecksing
|
Genomic Variants
for FAM132B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM132B (239067623 - 239077541 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM132B: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for FAM132B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM132B for disorders About MalaCards
FAM132B for disorders About GeneDecksing
OMIM gene information: 615099
OMIM disorders: --
Export disorders for FAM132B gene to outside databases
|
Publications
for FAM132B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM132B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM132B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Myonectin (CTRP15), a novel myokine that links skeleta l muscle to systemic lipid homeostasis. (PubMed id 22351773)1, 3 Seldin M.M....Wong G.W. (2012)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM132B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM132B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM132B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM132B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM132B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM132B gene:
Search GeneIP for patents involving FAM132B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM132B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM132B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM132B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM132B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM132B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM132B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM132B |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM132B |
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 | | | FAM132B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM132B |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM132B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM132B |
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