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Aliases for FAM131C Gene

Aliases for FAM131C Gene

  • Family With Sequence Similarity 131, Member C 2 3
  • C1orf117 3 4
  • Chromosome 1 Open Reading Frame 117 2
  • Protein FAM131C 3

External Ids for FAM131C Gene

Previous HGNC Symbols for FAM131C Gene

  • C1orf117

Previous GeneCards Identifiers for FAM131C Gene

  • GC01M016258
  • GC01M016384
  • GC01M014902

Summaries for FAM131C Gene

GeneCards Summary for FAM131C Gene

FAM131C (Family With Sequence Similarity 131, Member C) is a Protein Coding gene. An important paralog of this gene is FAM131A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM131C Gene

Genomics for FAM131C Gene

Regulatory Elements for FAM131C Gene

Genomic Location for FAM131C Gene

16,057,769 bp from pter
16,073,632 bp from pter
15,864 bases
Minus strand

Genomic View for FAM131C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM131C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM131C Gene

Proteins for FAM131C Gene

  • Protein details for FAM131C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM131C
    Protein Accession:
    Secondary Accessions:
    • Q5T5Q5
    • Q8N3X3
    • Q8N9P9

    Protein attributes for FAM131C Gene

    280 amino acids
    Molecular mass:
    30351 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM131C Gene

Proteomics data for FAM131C Gene at MOPED

Post-translational modifications for FAM131C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM131C Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for FAM131C Gene

Domains for FAM131C Gene

Protein Domains for FAM131C Gene


Suggested Antigen Peptide Sequences for FAM131C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96AQ9
  • Belongs to the FAM131 family.
genes like me logo Genes that share domains with FAM131C: view

No data available for Gene Families for FAM131C Gene

Function for FAM131C Gene

Gene Ontology (GO) - Molecular Function for FAM131C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with FAM131C: view

Animal Model Products

CRISPR Products

miRNA for FAM131C Gene

miRTarBase miRNAs that target FAM131C

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM131C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM131C Gene

Localization for FAM131C Gene

Subcellular locations from

Jensen Localization Image for FAM131C Gene COMPARTMENTS Subcellular localization image for FAM131C gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM131C Gene

Pathways for FAM131C Gene

SuperPathways for FAM131C Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM131C Gene


No data available for Pathways by source for FAM131C Gene

Transcripts for FAM131C Gene

mRNA/cDNA for FAM131C Gene

Unigene Clusters for FAM131C Gene

Family with sequence similarity 131, member C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM131C

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM131C Gene

No ASD Table

Relevant External Links for FAM131C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM131C Gene

mRNA expression in normal human tissues for FAM131C Gene

mRNA differential expression in normal tissues according to GTEx for FAM131C Gene

This gene is overexpressed in Brain - Cerebellum (10.5), Brain - Cerebellar Hemisphere (9.7), and Brain - Spinal cord (cervical c-1) (5.6).

SOURCE GeneReport for Unigene cluster for FAM131C Gene Hs.126825

genes like me logo Genes that share expressions with FAM131C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for FAM131C Gene

Orthologs for FAM131C Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM131C Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM131C 35
  • 83.72 (n)
  • 77.69 (a)
FAM131C 36
  • 71 (a)
(Canis familiaris)
Mammalia FAM131C 35
  • 86.03 (n)
  • 83.09 (a)
FAM131C 36
  • 77 (a)
(Mus musculus)
Mammalia Fam131c 35
  • 81.99 (n)
  • 80.88 (a)
Fam131c 16
Fam131c 36
  • 77 (a)
(Pan troglodytes)
Mammalia FAM131C 35
  • 98.45 (n)
  • 98.21 (a)
FAM131C 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam131c 35
  • 82.26 (n)
  • 81.75 (a)
(Monodelphis domestica)
Mammalia FAM131C 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia FAM131C 36
  • 49 (a)
(Anolis carolinensis)
Reptilia FAM131C 36
  • 49 (a)
(Danio rerio)
Actinopterygii fam131c 35
  • 57.76 (n)
  • 49.5 (a)
fam131c 36
  • 33 (a)
Species with no ortholog for FAM131C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM131C Gene

Gene Tree for FAM131C (if available)
Gene Tree for FAM131C (if available)

Paralogs for FAM131C Gene

Paralogs for FAM131C Gene Pseudogenes for FAM131C Gene

genes like me logo Genes that share paralogs with FAM131C: view

Variants for FAM131C Gene

Sequence variations from dbSNP and Humsavar for FAM131C Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs945407 -- 16,058,959(+) GGACA(A/G)CCAGT intron-variant
rs945408 -- 16,058,968(+) GTGCT(C/G)CTCTG intron-variant
rs1055081 -- 16,058,004(-) TGTCT(G/T)CCCCC utr-variant-3-prime
rs1414499 -- 16,064,318(+) TCACC(C/T)GGATC intron-variant
rs1414500 -- 16,064,493(+) CCTGC(A/G)GTGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM131C Gene

Variant ID Type Subtype PubMed ID
nsv871162 CNV Gain 21882294
nsv508936 CNV Insertion 20534489
dgv174n71 CNV Loss 21882294
nsv833758 CNV Gain+Loss 17160897
dgv175n71 CNV Gain 21882294
dgv176n71 CNV Loss 21882294
nsv520148 CNV Loss 19592680
nsv871485 CNV Loss 21882294
nsv524045 CNV Loss 19592680
nsv470698 CNV Loss 18288195
nsv870526 CNV Loss 21882294
esv25815 CNV Gain 19812545
dgv177n71 CNV Loss 21882294
nsv829570 CNV Gain 20364138
esv2434454 CNV Deletion 19546169
esv995840 CNV Deletion 20482838
dgv19e201 CNV Deletion 23290073
nsv436443 CNV Deletion 17901297
dgv20e199 CNV Deletion 23128226
dgv1e19 CNV Loss 19470904
nsv871112 CNV Gain 21882294
esv32650 CNV Gain 17666407
esv6377 CNV Loss 19470904
esv2672024 CNV Deletion 23128226
esv2744386 CNV Deletion 23290073
nsv870466 CNV Loss 21882294
nsv870801 CNV Loss 21882294

Relevant External Links for FAM131C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM131C Gene

Disorders for FAM131C Gene

Relevant External Links for FAM131C

Genetic Association Database (GAD)

No disorders were found for FAM131C Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM131C Gene

Publications for FAM131C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PMID: 19734545) Need A.C. … Goldstein D.B. (Hum. Mol. Genet. 2009) 3 48
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for FAM131C Gene

Sources for FAM131C Gene

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