FAM131C Gene
protein-coding GIFtS: 39
GCID: GC01M016384
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family with sequence similarity 131, member C(Previous name: chromosome 1 open reading frame 117 )
(Previous symbol: C1orf117)
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Aliases
for FAM131C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 131, Member C1 2 | | C1orf1171 2 3 | | FLJ367661 | | Chromosome 1 Open Reading Frame 1171 | | RP11-5P18.92 | | Protein FAM131C2 |
Export aliases for FAM131C gene to outside databasesPrevious GC identifers: GC01M016258 GC01M014902 |
Summaries
for FAM131C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM131C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM131C gene promoter:
HFH-3 Brachyury LCR-F1 E47 AREB6 CREB FOXI1 POU2F1 deltaCREB POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM131C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM131C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.13 Ensembl cytogenetic band: 1p36.13 HGNC cytogenetic band: 1p36.13FAM131C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M016384: view genomic region
(about GC identifiers)
Start:
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16,384,264 bp from pter |
End:
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16,400,127 bp from pter |
Size:
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15,864 bases |
Orientation:
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minus strand |
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Proteins
for FAM131C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F131C_HUMAN, Q96AQ9 (See
protein sequence)Recommended Name: Protein FAM131C Size: 280 amino acids; 30351 Da
Secondary accessions: Q5T5Q5 Q8N3X3 Q8N9P9Explore the universe of human proteins at neXtProt for FAM131C: NX_Q96AQ9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96AQ9
FAM131C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_872429.2
ENSEMBL proteins: ENSP00000364814
Human Recombinant Protein Products:
FAM131C Antibody Products:
Assay Products for FAM131C: |
Protein
Domains /
Families
for FAM131C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM131C for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96AQ9ProtoNet protein and cluster: Q96AQ9 UniProtKB/Swiss-Prot: F131C_HUMAN, Q96AQ9Similarity: Belongs to the FAM131 family |
Function
for FAM131C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM131C (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM131C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM131C (NM_182623) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM131C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM131C |
|
Pathways & Interactions
for FAM131C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM131C
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/7 Interacting proteins for FAM131C (Q96AQ93 ENSP000003648144) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
|
Drugs & Compounds
for FAM131C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM131C
Search CenterWatch for drugs/clinical trials and news about FAM131C / F131C
|
Transcripts
for FAM131C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM131C gene: NM_182623.2 Unigene Cluster for FAM131C: Family with sequence similarity 131, member C Hs.126825 [show with all ESTs]Unigene Representative Sequence: BC0373942 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000375662(uc001axz.4) ENST00000494078
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM131C (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM131C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM131C (NM_182623) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM131C | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM131C |
Additional cDNA sequence: AK094085.1 BC016848.1 BC037394.1 6 DOTS entries: DT.102118 DT.100722130 DT.121415159 DT.121415045 DT.121415064 DT.121415170 24/31 AceView cDNA sequences (see all 31): AI690510 BC016848 BI915295 BM546083 NM_182623 AK094085 BM264211 BM263911 BC037394 BE672097 AL529663 AL522414 R61730 BQ067964 CA424474 AL522415 AA931428 AI864545 CA773504 BM807463 T10170 AW450211 AL529662 BX329825
GeneLoc Exon Structure
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Expression
for FAM131C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM131C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAGAACTG
About this image
See FAM131C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM131C
SOURCE GeneReport for Unigene cluster: Hs.126825
SABiosciences Custom PCR Arrays for FAM131C
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM131C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM131C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM131C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM131C |
Orthologs
for FAM131C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM131C gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
FAM131C6 |
-- |
53(a) |
1 ↔ 1 |
GL343609.1(381876-386456) |
zebrafish
(Danio rerio) |
Actinopterygii |
fam131c1 |
family with sequence similarity 131, member C |
56.81(n)
48.28(a) |
|
619198 NM_001033590.1 NP_001028762.1 |
ENSEMBL Gene Tree for FAM131C (if available)
TreeFam Gene Tree for FAM131C (if available) |
Paralogs
for FAM131C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM131C gene
- FAM131B2 FAM131A2
FAM131C for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for FAM131C
PGOHUM00000243909
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Genomic Variants
for FAM131C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM131C (16384264 - 16400127 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for FAM131C
5 CNVs: 22889 6792 97300 63115 74196 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM131C |
|
Disorders
/ Diseases
for FAM131C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM131C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM131C gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM131C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)1 Toyoshima M....Grandori C. (2012)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
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External Searches for FAM131C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM131C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM131C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM131C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM131C | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM131C gene:
Search GeneIP for patents involving FAM131C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM131C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM131C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM131C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM131C | | | OriGene Protein Over-expression Lysate for FAM131C | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM131C | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM131C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM131C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM131C | | OriGene Custom Protein Services for FAM131C | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM131C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM131C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM131C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM131C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM131C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM131C |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM131C |
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 | | | FAM131C Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibodies for FAM131C |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM131C |
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