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Aliases for FAM131A Gene

Aliases for FAM131A Gene

  • Family With Sequence Similarity 131, Member A 2 3
  • C3orf40 3 4
  • Chromosome 3 Open Reading Frame 40 2
  • Protein FAM131A 3
  • FLAT715 3
  • PRO1378 3

External Ids for FAM131A Gene

Previous HGNC Symbols for FAM131A Gene

  • C3orf40

Previous GeneCards Identifiers for FAM131A Gene

  • GC03P185538
  • GC03P184053
  • GC03P181460

Summaries for FAM131A Gene

GeneCards Summary for FAM131A Gene

FAM131A (Family With Sequence Similarity 131, Member A) is a Protein Coding gene. An important paralog of this gene is FAM131C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM131A Gene

Genomics for FAM131A Gene

Regulatory Elements for FAM131A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM131A Gene

184,335,926 bp from pter
184,346,275 bp from pter
10,350 bases
Plus strand

Genomic View for FAM131A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM131A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM131A Gene

Proteins for FAM131A Gene

  • Protein details for FAM131A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM131A
    Protein Accession:
    Secondary Accessions:
    • D3DNT6
    • G5E9B1
    • Q8TA84

    Protein attributes for FAM131A Gene

    335 amino acids
    Molecular mass:
    36108 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM131A Gene


neXtProt entry for FAM131A Gene

Proteomics data for FAM131A Gene at MOPED

Post-translational modifications for FAM131A Gene

No Post-translational modifications

Antibody Products

No data available for DME Specific Peptides for FAM131A Gene

Domains for FAM131A Gene

Protein Domains for FAM131A Gene


Suggested Antigen Peptide Sequences for FAM131A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM131 family.
  • Belongs to the FAM131 family.
genes like me logo Genes that share domains with FAM131A: view

No data available for Gene Families for FAM131A Gene

Function for FAM131A Gene

Phenotypes for FAM131A Gene

GenomeRNAi human phenotypes for FAM131A:
genes like me logo Genes that share phenotypes with FAM131A: view

Animal Model Products

CRISPR Products

miRNA for FAM131A Gene

miRTarBase miRNAs that target FAM131A

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM131A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM131A Gene

Localization for FAM131A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM131A Gene


Subcellular locations from

Jensen Localization Image for FAM131A Gene COMPARTMENTS Subcellular localization image for FAM131A gene
Compartment Confidence
extracellular 3
lysosome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for FAM131A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM131A: view

Pathways for FAM131A Gene

SuperPathways for FAM131A Gene

No Data Available

Interacting Proteins for FAM131A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000373360 Q6UXB0-F131A_HUMAN for FAM131A Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM131A Gene


No data available for Pathways by source for FAM131A Gene

Transcripts for FAM131A Gene

Unigene Clusters for FAM131A Gene

Family with sequence similarity 131, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM131A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM131A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d
SP1: - - - -
SP2: - - - - -
SP3: - - - -
SP4: - -
SP6: - - - - - -

Relevant External Links for FAM131A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM131A Gene

mRNA expression in normal human tissues for FAM131A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM131A Gene

SOURCE GeneReport for Unigene cluster for FAM131A Gene Hs.591307

genes like me logo Genes that share expressions with FAM131A: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for FAM131A Gene

Orthologs for FAM131A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM131A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM131A 35
  • 92.99 (n)
  • 96.17 (a)
FAM131A 36
  • 96 (a)
(Canis familiaris)
Mammalia FAM131A 35
  • 93.17 (n)
  • 96.72 (a)
FAM131A 36
  • 96 (a)
(Mus musculus)
Mammalia Fam131a 35
  • 89.72 (n)
  • 93.89 (a)
Fam131a 16
Fam131a 36
  • 94 (a)
(Pan troglodytes)
Mammalia FAM131A 35
  • 99 (n)
  • 98.91 (a)
FAM131A 36
  • 78 (a)
(Rattus norvegicus)
Mammalia Fam131a 35
  • 88.98 (n)
  • 93.06 (a)
(Monodelphis domestica)
Mammalia FAM131A 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia FAM131A 36
  • 76 (a)
(Gallus gallus)
Aves FAM131A 35
  • 68.87 (n)
  • 64.67 (a)
FAM131A 36
  • 57 (a)
(Anolis carolinensis)
Reptilia FAM131A 36
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam131a 35
  • 59.24 (n)
  • 60.83 (a)
(Danio rerio)
Actinopterygii zgc:165508 35
  • 59.95 (n)
  • 63.88 (a)
FAM131A 36
  • 51 (a)
Species with no ortholog for FAM131A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM131A Gene

Gene Tree for FAM131A (if available)
Gene Tree for FAM131A (if available)

Paralogs for FAM131A Gene

Paralogs for FAM131A Gene

(2) SIMAP similar genes for FAM131A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM131A: view

Variants for FAM131A Gene

Sequence variations from dbSNP and Humsavar for FAM131A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1105000 -- 184,338,098(+) GGAAA(C/T)GGGAA intron-variant
rs1881973 -- 184,338,313(-) ATTGC(C/G)GTATC intron-variant
rs2293604 -- 184,336,894(-) CTGAT(A/G)CACAG intron-variant, upstream-variant-2KB
rs2889404 -- 184,340,356(-) gctac(A/G)gtgca intron-variant
rs3064290 -- 184,343,993(-) GTCTC(-/AA/TA)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM131A Gene

Variant ID Type Subtype PubMed ID
nsv878057 CNV Loss 21882294
nsv878060 CNV Loss 21882294
nsv829813 CNV Loss 17160897
esv2422400 CNV Duplication 17116639
esv2726297 CNV Deletion 23290073

Relevant External Links for FAM131A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM131A Gene

Disorders for FAM131A Gene

No disorders were found for FAM131A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM131A Gene

Publications for FAM131A Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for FAM131A Gene

Sources for FAM131A Gene

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