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Aliases for FAM131A Gene

Aliases for FAM131A Gene

  • Family With Sequence Similarity 131, Member A 2 3
  • C3orf40 3 4
  • Chromosome 3 Open Reading Frame 40 2
  • Protein FAM131A 3
  • FLAT715 3
  • PRO1378 3

External Ids for FAM131A Gene

Previous Symbols for FAM131A Gene

  • C3orf40

Summaries for FAM131A Gene

GeneCards Summary for FAM131A Gene

FAM131A (Family With Sequence Similarity 131, Member A) is a Protein Coding gene. An important paralog of this gene is FAM131C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM131A Gene

Genomics for FAM131A Gene

Genomic Location for FAM131A Gene

Start:
184,335,926 bp from pter
End:
184,346,275 bp from pter
Size:
10,350 bases
Orientation:
Plus strand

Genomic View for FAM131A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM131A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM131A Gene

Regulatory Elements for FAM131A Gene

Proteins for FAM131A Gene

  • Protein details for FAM131A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXB0-F131A_HUMAN
    Recommended name:
    Protein FAM131A
    Protein Accession:
    Q6UXB0
    Secondary Accessions:
    • D3DNT6
    • G5E9B1
    • Q8TA84

    Protein attributes for FAM131A Gene

    Size:
    335 amino acids
    Molecular mass:
    36108 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM131A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM131A Gene

Proteomics data for FAM131A Gene at MOPED

Post-translational modifications for FAM131A Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM131A Gene

Domains for FAM131A Gene

Protein Domains for FAM131A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F131A_HUMAN
Family:
  • Belongs to the FAM131 family.:
    • Q6UXB0
genes like me logo Genes that share domains with FAM131A: view

No data available for Gene Families for FAM131A Gene

Function for FAM131A Gene

Phenotypes for FAM131A Gene

GenomeRNAi human phenotypes for FAM131A:
genes like me logo Genes that share phenotypes with FAM131A: view

miRNA for FAM131A Gene

miRTarBase miRNAs that target FAM131A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM131A Gene

Localization for FAM131A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM131A Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM131A Gene COMPARTMENTS Subcellular localization image for FAM131A gene
Compartment Confidence
extracellular 3
lysosome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for FAM131A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM131A: view

Pathways for FAM131A Gene

SuperPathways for FAM131A Gene

No Data Available

Interacting Proteins for FAM131A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000373360%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000373360 Q6UXB0-F131A_HUMAN for FAM131A Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM131A Gene

None

No data available for Pathways by source for FAM131A Gene

Transcripts for FAM131A Gene

Unigene Clusters for FAM131A Gene

Family with sequence similarity 131, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM131A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d
SP1: - - - -
SP2: - - - - -
SP3: - - - -
SP4: - -
SP5:
SP6: - - - - - -
SP7:

Relevant External Links for FAM131A Gene

GeneLoc Exon Structure for
FAM131A
ECgene alternative splicing isoforms for
FAM131A

Expression for FAM131A Gene

mRNA expression in normal human tissues for FAM131A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM131A Gene

SOURCE GeneReport for Unigene cluster for FAM131A Gene Hs.591307

genes like me logo Genes that share expressions with FAM131A: view

Orthologs for FAM131A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM131A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM131A 36
  • 99 (n)
  • 98.91 (a)
FAM131A 37
  • 78 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM131A 36
  • 92.99 (n)
  • 96.17 (a)
FAM131A 37
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM131A 36
  • 93.17 (n)
  • 96.72 (a)
FAM131A 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam131a 36
  • 89.72 (n)
  • 93.89 (a)
Fam131a 16
Fam131a 37
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM131A 37
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM131A 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam131a 36
  • 88.98 (n)
  • 93.06 (a)
chicken
(Gallus gallus)
Aves FAM131A 36
  • 68.87 (n)
  • 64.67 (a)
FAM131A 37
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM131A 37
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam131a 36
  • 59.24 (n)
  • 60.83 (a)
zebrafish
(Danio rerio)
Actinopterygii FAM131A 37
  • 51 (a)
OneToOne
zgc:165508 36
  • 59.95 (n)
  • 63.88 (a)
Species with no ortholog for FAM131A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM131A Gene

ENSEMBL:
Gene Tree for FAM131A (if available)
TreeFam:
Gene Tree for FAM131A (if available)

Paralogs for FAM131A Gene

Paralogs for FAM131A Gene

Selected SIMAP similar genes for FAM131A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM131A: view

Variants for FAM131A Gene

Sequence variations from dbSNP and Humsavar for FAM131A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1105000 -- 184,338,098(+) GGAAA(C/T)GGGAA intron-variant
rs1881973 -- 184,338,313(-) ATTGC(C/G)GTATC intron-variant
rs2293604 -- 184,336,894(-) CTGAT(A/G)CACAG intron-variant, upstream-variant-2KB
rs2889404 -- 184,340,356(-) gctac(A/G)gtgca intron-variant
rs3064290 -- 184,343,993(-) GTCTC(-/AA/TA)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM131A Gene

Variant ID Type Subtype PubMed ID
nsv878057 CNV Loss 21882294
nsv878060 CNV Loss 21882294
nsv829813 CNV Loss 17160897
esv2422400 CNV Duplication 17116639
esv2726297 CNV Deletion 23290073

Relevant External Links for FAM131A Gene

HapMap Linkage Disequilibrium report
FAM131A

Disorders for FAM131A Gene

No disorders were found for FAM131A Gene.

No data available for UniProtKB/Swiss-Prot for FAM131A Gene

Publications for FAM131A Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for FAM131A Gene

Sources for FAM131A Gene

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