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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAM129B Gene

protein-coding   GIFtS: 49
GCID: GC09M130267

family with sequence similarity 129, member B

(Previous name: chromosome 9 open reading frame 88 )
(Previous symbol: C9orf88)
 Explore 1 disease affiliated with
FAM129B via our new
 Human Malady Compendium 
Biological research products
for FAM129B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Family With Sequence Similarity 129, Member B1 2     FLJ222981
C9orf881 2 3     Chromosome 9 Open Reading Frame 881
MINERVA1 2 3     MEG-32
BA356B19.61     OC582
Melanoma Invasion By ERK2 3     Niban-Like Protein 12
DKFZP434H08201     Meg-33
FLJ135181     Protein FAM129B3
FLJ221511     

External Ids:    HGNC: 252821   Entrez Gene: 648552   Ensembl: ENSG000001368307   OMIM: 6140455   UniProtKB: Q96TA13   

Export aliases for FAM129B gene to outside databases

Previous GC identifers: GC09M129309 GC09M099885


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NIBL1_HUMAN, Q96TA1
Function: May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM129B gene promoter:
         c-Fos   PPAR-gamma1   AP-1   NCX/Ncx   c-Jun   PPAR-gamma2   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAM129B promoter sequence
   Search SABiosciences Chromatin IP Primers for FAM129B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM129B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.13

FAM129B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM129B gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M130267:  view genomic region     (about GC identifiers)

Start:
130,267,618 bp from pter      End:
130,341,268 bp from pter
Size:
73,651 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NIBL1_HUMAN, Q96TA1 (See protein sequence)
Recommended Name: Niban-like protein 1  
Size: 746 amino acids; 84138 Da
Subcellular location: Cytoplasm, cytosol. Cell junction, adherens junction. Note=In exponentially growing cells,
exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In
melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation
Secondary accessions: Q4LE55 Q5VVW6 Q5VVW7 Q9BUS2 Q9NT35
Alternative splicing: 2 isoforms:  Q96TA1-1   Q96TA1-2   

Explore the universe of human proteins at neXtProt for FAM129B: NX_Q96TA1

Post-translational modifications:

  • Phosphorylated at Ser-641, Ser-646, Ser-692 and Ser-696 by the BRAF/MKK/ERK signaling cascade. In melanoma cells, the
  • C-terminal phosphorylation may prevent targeting to the plasma membrane1
  • As apoptosis proceeds, degraded via an proteasome-independent pathway, probably by caspases (PubMed:21148485)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96TA1

  • FAM129B Protein expression data from MOPED and PaxDb:    About this image 
    FAM129B Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001030611.1  NP_073744.2  

    ENSEMBL proteins: 
     ENSP00000362411   ENSP00000362409  

    Human Recombinant Protein Products for FAM129B: 
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    Uscn Proteins for FAM129B

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634NOT nucleus IDA--
    GO:0005829cytosol IDA--
    GO:0005912adherens junction IDA--

    FAM129B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FAM129B for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR026088 Niban_like

    Graphical View of Domain Structure for InterPro Entry Q96TA1

    ProtoNet protein and cluster: Q96TA1

    1 Blocks protein family: IPB001849 Pleckstrin-like

    UniProtKB/Swiss-Prot: NIBL1_HUMAN, Q96TA1
    Similarity: Belongs to the Niban family
    Similarity: Contains 1 PH domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NIBL1_HUMAN, Q96TA1
    Function: May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005543phospholipid binding IEA--
         
    FAM129B for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for FAM129B:
     Decreased cell number, increas  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for FAM129B 

    miRNA
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    miRTarBase miRNAs that target FAM129B:
    hsa-mir-124 (MIRT004925)

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    hsa-miR-142-5p hsa-miR-125a-5p hsa-miR-411 hsa-miR-106a hsa-miR-124 hsa-miR-125b hsa-miR-93 hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidFAM129B 3' UTR sequence
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM129B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1MAP Kinase Signaling
    MAP Kinase Signaling1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for FAM129B
        MAP Kinase Signaling



    FAM129B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM129B

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/743 Interacting proteins for FAM129B (Q96TA11, 2, 3 ENSP000003624094) via UniProtKB, MINT, STRING, and/or I2D (see all 743)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZNF512BQ96KM62, 3MINT-60822 I2D: score=2 
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    KEAP1Q141453, ENSP000001711114I2D: score=2 STRING: ENSP00000171111
    ABCF1Q8NE712MINT-7945693 MINT-7947479
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043066negative regulation of apoptotic process IMP--

    FAM129B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAM129B
    Search CenterWatch for drugs/clinical trials and news about FAM129B / NIBL1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAM129B gene (2 alternative transcripts): 
    NM_001035534.1  NM_022833.2  

    Unigene Cluster for FAM129B:

    Family with sequence similarity 129, member B
    Hs.522401  [show with all ESTs]
    Unigene Representative Sequence: NM_022833
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373314(uc004bri.3) ENST00000373312(uc004brh.3 uc004brj.4)
    ENST00000478917 ENST00000468379 ENST00000484348 ENST00000465154 ENST00000476091


    miRNA
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    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM129B (see all 18):
    hsa-miR-142-5p hsa-miR-125a-5p hsa-miR-411 hsa-miR-106a hsa-miR-124 hsa-miR-125b hsa-miR-93 hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidFAM129B 3' UTR sequence
    Inhib. RNA
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    Sirion Biotech Custom design and validation of potent shRNA sequences against FAM129B 
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    Additional cDNA sequence: 

    AB210016.1 AF151783.1 AF192911.1 AK023580.1 AK025804.1 AK025951.1 AL137555.1 BC001979.1 
    BC018849.2 BC023210.1 BC110345.1 

    18 DOTS entries:

    DT.100803359  DT.40121502  DT.445956  DT.100802521  DT.100038716  DT.102834539  DT.75199470  DT.121147553 
    DT.91742274  DT.100813600  DT.121147609  DT.70102968  DT.85105661  DT.92032142  DT.95269138  DT.95346269 
    DT.99958544  DT.91945768 

    24/498 AceView cDNA sequences (see all 498):

    BQ650809 BQ434790 BQ900276 BP366066 AI362616 BQ948083 BX280720 BM450097 
    CB136900 BU631348 NM_022833 BM720223 CO250152 BQ883654 BU190217 BQ919097 
    BQ958860 BQ647726 AW630976 BC018849 BQ882950 AI500700 BI334843 AJ403121 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FAM129B (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20a · 20b
    SP1:                    -     -     -     -     -                                         -                                                                     
    SP2:                    -     -     -     -     -                                         -                                                                     
    SP3:                    -     -     -     -     -                       -     -     -     -     -     -     -     -     -     -     -     -                     
    SP4:        -     -     -     -     -     -     -                                                                                                               
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for FAM129B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAM129B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTCTACTAA
    FAM129B Expression
    About this image
    See FAM129B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAM129B

    SOURCE GeneReport for Unigene cluster: Hs.522401
        SABiosciences Custom PCR Arrays for FAM129B

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM129B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FAM129B gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves FAM129B1 family with sequence similarity 129, member B 79.66(n)
    78.29(a)
      771307  XM_003642273.1  XP_003642321.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM129B6
    --
    65(a)
    1 ↔ 1
    GL343556.1(8068-55260)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.81242 Transcribed sequence with moderate similarity to protein more 76.84(n)    BX710375.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam129ba1 family with sequence similarity 129, member Ba 65.27(n)
    60.18(a)
      563073  NM_001080586.1  NP_001074055.1 


    ENSEMBL Gene Tree for FAM129B (if available)
    TreeFam Gene Tree for FAM129B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAM129B gene
    FAM129A2  FAM129C2  
    1 SIMAP similar gene for FAM129B using alignment to 2 protein entries:     NIBL1_HUMAN (see all proteins):
    FAM129A

    FAM129B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1394 NCBI SNPs in FAM129B are shown (see all 1394    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs48371581,2
    C,F,A,H--130267156(+) TCTCTC/TGAGGC 2 -- int1 ds500111Minor allele frequency- T:0.14NS EA NA WA 776
    rs122357401,2
    C,F--130267331(+) CTGCTG/ACCATC 2 -- ds5001 int16Minor allele frequency- A:0.19NA EA 248
    rs1828030891,2
    --130267374(+) GAGGGC/GCACCC 2 -- int1 ds50010--------
    rs562477391,2
    C--130267406(+) GCTGCC/GTGTGC 2 -- int1 ds50010--------
    rs1382237671,2
    --130267541(+) AAGCCA/GAGCCG 2 -- ds5001 int10--------
    rs1436038031,2
    --130267547(+) AGCCGC/TATGGG 2 -- ds5001 int10--------
    rs22452841,2
    C,F,A--130267563(+) AGACAT/CAGTCC 2 -- ds5001 int19Minor allele frequency- C:0.38NA WA CSA EA 370
    rs1460473021,2
    --130267759(+) AGATGC/TGCCAG 2 -- ut310--------
    rs12771,2
    C,A,H--130267777(+) GGCTGG/CGGCAG 2 -- ut31 ese313Minor allele frequency- C:0.46MN EA NA CSA WA 2241
    rs12761,2
    C,F,A,H--130267856(+) GTCTAG/CGGCAC 2 -- ut31 ese314Minor allele frequency- C:0.24EA MN NS NA CSA WA 2431

    HapMap Linkage Disequilibrium report for FAM129B (130267618 - 130341268 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FAM129B: --

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FAM129B for disorders           About GeneDecksing

    OMIM gene information: 614045    OMIM disorders: --

    1 disease for FAM129B:    About MalaCards
    melanoma


    Export disorders for FAM129B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAM129B gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with FAM129B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. (PubMed id 19362540)1, 2, 3 Old W.M....Ahn N.G. (2009)
    2. FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells. (PubMed id 21148485)1, 2 Chen S....Evans D.R. (2011)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 3 Ota T.... Sugano S. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64855 HGNC: 25282 AceView: C9orf88 Ensembl:ENSG00000136830 euGenes: HUgn64855
    ECgene: FAM129B H-InvDB: FAM129B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAM129B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FAM129B gene:
    Search GeneIP for patents involving FAM129B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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