Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM124A Gene

Aliases for FAM124A Gene

  • Family With Sequence Similarity 124A 2 3

External Ids for FAM124A Gene

Previous GeneCards Identifiers for FAM124A Gene

  • GC13P050695
  • GC13P051796
  • GC13P032585

Summaries for FAM124A Gene

GeneCards Summary for FAM124A Gene

FAM124A (Family With Sequence Similarity 124A) is a Protein Coding gene. An important paralog of this gene is FAM124B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM124A Gene

Genomics for FAM124A Gene

Regulatory Elements for FAM124A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM124A Gene

51,222,334 bp from pter
51,284,241 bp from pter
61,908 bases
Plus strand

Genomic View for FAM124A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM124A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM124A Gene

Proteins for FAM124A Gene

  • Protein details for FAM124A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM124A
    Protein Accession:
    Secondary Accessions:
    • A2A324
    • Q8N8P9
    • Q8NE66
    • Q96NJ9

    Protein attributes for FAM124A Gene

    546 amino acids
    Molecular mass:
    60104 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH34497.1; Type=Frameshift; Positions=286; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM124A Gene


neXtProt entry for FAM124A Gene

Proteomics data for FAM124A Gene at MOPED

Post-translational modifications for FAM124A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM124A Gene

No data available for DME Specific Peptides for FAM124A Gene

Domains & Families for FAM124A Gene

Protein Domains for FAM124A Gene


Suggested Antigen Peptide Sequences for FAM124A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM124 family.
  • Belongs to the FAM124 family.
genes like me logo Genes that share domains with FAM124A: view

No data available for Gene Families for FAM124A Gene

Function for FAM124A Gene

Gene Ontology (GO) - Molecular Function for FAM124A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM124A: view

Phenotypes for FAM124A Gene

GenomeRNAi human phenotypes for FAM124A:
genes like me logo Genes that share phenotypes with FAM124A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM124A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM124A Gene

Localization for FAM124A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM124A Gene

Pathways & Interactions for FAM124A Gene

SuperPathways for FAM124A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM124A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM124A Gene

Drugs & Compounds for FAM124A Gene

No Compound Related Data Available

Transcripts for FAM124A Gene

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM124A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM124A Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b
SP1: -
SP2: - -

Relevant External Links for FAM124A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM124A Gene

mRNA expression in normal human tissues for FAM124A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM124A Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x6.2).

Protein differential expression in normal tissues from HIPED for FAM124A Gene

This gene is overexpressed in Monocytes (18.0), Spleen (11.1), Uterus (7.7), and Lymph node (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM124A Gene

SOURCE GeneReport for Unigene cluster for FAM124A Gene Hs.71913

genes like me logo Genes that share expression patterns with FAM124A: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM124A Gene

Orthologs for FAM124A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM124A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM124A 35
  • 82.29 (n)
  • 76.47 (a)
FAM124A 36
  • 76 (a)
(Canis familiaris)
Mammalia FAM124A 35
  • 86.88 (n)
  • 85.92 (a)
FAM124A 36
  • 85 (a)
(Mus musculus)
Mammalia Fam124a 35
  • 79.23 (n)
  • 74.63 (a)
Fam124a 16
Fam124a 36
  • 73 (a)
(Pan troglodytes)
Mammalia FAM124A 35
  • 99.54 (n)
  • 99.66 (a)
FAM124A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam124a 35
  • 78.79 (n)
  • 74.63 (a)
(Monodelphis domestica)
Mammalia FAM124A 36
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia FAM124A 36
  • 72 (a)
(Gallus gallus)
Aves FAM124A 35
  • 63.69 (n)
  • 62.13 (a)
FAM124A 36
  • 55 (a)
(Anolis carolinensis)
Reptilia FAM124A 36
  • 47 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam124a 35
  • 60.03 (n)
  • 57.77 (a)
(Danio rerio)
Actinopterygii LOC556683 35
  • 56.03 (n)
  • 52.26 (a)
FAM124A 36
  • 39 (a)
Species with no ortholog for FAM124A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM124A Gene

Gene Tree for FAM124A (if available)
Gene Tree for FAM124A (if available)

Paralogs for FAM124A Gene

Paralogs for FAM124A Gene

(1) SIMAP similar genes for FAM124A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM124A: view

Variants for FAM124A Gene

Sequence variations from dbSNP and Humsavar for FAM124A Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
VAR_032098 -

Structural Variations from Database of Genomic Variants (DGV) for FAM124A Gene

Variant ID Type Subtype PubMed ID
nsv832610 CNV Gain 17160897
nsv832611 CNV Loss 17160897
esv2747418 CNV Deletion 23290073

Variation tolerance for FAM124A Gene

Residual Variation Intolerance Score: 74.71% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.81; 79.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM124A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM124A Gene

Disorders for FAM124A Gene

Relevant External Links for FAM124A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM124A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM124A Gene

Publications for FAM124A Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 67
  2. A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. (PMID: 24532677) Bossini-Castillo L. … Koeleman B.P. (Ann. Rheum. Dis. 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 67
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67

Products for FAM124A Gene

Sources for FAM124A Gene

Back to Top