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Aliases for FAM122C Gene

Aliases for FAM122C Gene

  • Family With Sequence Similarity 122C 2 3

External Ids for FAM122C Gene

Previous GeneCards Identifiers for FAM122C Gene

  • GC0XP133768
  • GC0XP133941
  • GC0XP123328

Summaries for FAM122C Gene

GeneCards Summary for FAM122C Gene

FAM122C (Family With Sequence Similarity 122C) is a Protein Coding gene. An important paralog of this gene is FAM122B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM122C Gene

Genomics for FAM122C Gene

Regulatory Elements for FAM122C Gene

Genomic Location for FAM122C Gene

Start:
134,796,413 bp from pter
End:
134,855,119 bp from pter
Size:
58,707 bases
Orientation:
Plus strand

Genomic View for FAM122C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM122C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM122C Gene

Proteins for FAM122C Gene

  • Protein details for FAM122C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P4D5-F222C_HUMAN
    Recommended name:
    Protein FAM122C
    Protein Accession:
    Q6P4D5
    Secondary Accessions:
    • F5H036
    • Q8WVK9

    Protein attributes for FAM122C Gene

    Size:
    195 amino acids
    Molecular mass:
    22522 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM122C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM122C Gene

Proteomics data for FAM122C Gene at MOPED

Post-translational modifications for FAM122C Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM122C Gene

Domains for FAM122C Gene

Protein Domains for FAM122C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM122C Gene

Graphical View of Domain Structure for InterPro Entry

Q6P4D5

UniProtKB/Swiss-Prot:

F222C_HUMAN :
  • Q6P4D5
Family:
  • Belongs to the FAM122 family.
genes like me logo Genes that share domains with FAM122C: view

No data available for Gene Families for FAM122C Gene

Function for FAM122C Gene

Animal Model Products

CRISPR Products

miRNA for FAM122C Gene

miRTarBase miRNAs that target FAM122C

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM122C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM122C Gene

Localization for FAM122C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM122C Gene COMPARTMENTS Subcellular localization image for FAM122C gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM122C Gene

Pathways for FAM122C Gene

SuperPathways for FAM122C Gene

No Data Available

Interacting Proteins for FAM122C Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000359820%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000403397%0d%0a
Selected Interacting proteins: ENSP00000359820 for FAM122C Gene via STRING

Gene Ontology (GO) - Biological Process for FAM122C Gene

None

No data available for Pathways by source for FAM122C Gene

Transcripts for FAM122C Gene

Unigene Clusters for FAM122C Gene

Family with sequence similarity 122C:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM122C

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM122C Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c
SP1: - - - - - -
SP2: - - - - - -
SP3:
SP4: - - -
SP5: - - - -
SP6: - - - -
SP7:
SP8:

Relevant External Links for FAM122C Gene

GeneLoc Exon Structure for
FAM122C
ECgene alternative splicing isoforms for
FAM122C

Expression for FAM122C Gene

mRNA expression in normal human tissues for FAM122C Gene

mRNA differential expression in normal tissues according to GTEx for FAM122C Gene

This gene is overexpressed in Ovary (5.0).

Protein differential expression in normal tissues for FAM122C Gene

This gene is overexpressed in Amniocyte (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM122C Gene

SOURCE GeneReport for Unigene cluster for FAM122C Gene Hs.269127

genes like me logo Genes that share expressions with FAM122C: view

Expression partners for FAM122C Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM122C Gene

Orthologs for FAM122C Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM122C Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia FAM122C 36
  • 23 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 29 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Fam122c 36
  • 27 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 29 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia FAM122C 36
  • 88 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM122A 36
  • 30 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii fam122b 36
  • 25 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG4497 36
  • 8 (a)
OneToMany
Species with no ortholog for FAM122C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM122C Gene

ENSEMBL:
Gene Tree for FAM122C (if available)
TreeFam:
Gene Tree for FAM122C (if available)

Paralogs for FAM122C Gene

Paralogs for FAM122C Gene

Selected SIMAP similar genes for FAM122C Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM122C: view

Variants for FAM122C Gene

Sequence variations from dbSNP and Humsavar for FAM122C Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1047858 -- 134,844,683(+) CATTT(G/T)TCTCC intron-variant
rs3174459 -- 134,811,108(+) TTAAT(A/G)CAGTA intron-variant, utr-variant-3-prime
rs4486359 -- 134,823,749(+) AATCT(A/C)CAACA intron-variant
rs5933466 -- 134,837,032(+) gactc(C/T)gtctt intron-variant
rs5933467 -- 134,838,547(+) ATCCA(A/C)CCACC intron-variant

Relevant External Links for FAM122C Gene

HapMap Linkage Disequilibrium report
FAM122C
Locus Specific Mutation Databases (LSDB)
FAM122C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM122C Gene

Disorders for FAM122C Gene

No disorders were found for FAM122C Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM122C Gene

Publications for FAM122C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for FAM122C Gene

Sources for FAM122C Gene

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