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Aliases for FAM122B Gene

Aliases for FAM122B Gene

  • Family With Sequence Similarity 122B 2 3
  • Synoviocyte Proliferation Associated In Collagen-Induced Arthritis 2 3
  • Protein FAM122B 3
  • RP11-308B5.5 3
  • SPACIA2 3

External Ids for FAM122B Gene

Previous GeneCards Identifiers for FAM122B Gene

  • GC0XM133731
  • GC0XM133903
  • GC0XM123302

Summaries for FAM122B Gene

GeneCards Summary for FAM122B Gene

FAM122B (Family With Sequence Similarity 122B) is a Protein Coding gene. An important paralog of this gene is FAM122C.

Gene Wiki entry for FAM122B Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM122B Gene

Genomics for FAM122B Gene

Regulatory Elements for FAM122B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM122B Gene

134,769,566 bp from pter
134,797,232 bp from pter
27,667 bases
Minus strand

Genomic View for FAM122B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM122B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM122B Gene

Proteins for FAM122B Gene

  • Protein details for FAM122B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM122B
    Protein Accession:
    Secondary Accessions:
    • A8K902
    • Q6PIM2
    • Q6ZU47
    • Q6ZV64
    • Q6ZVE4
    • Q8TB75

    Protein attributes for FAM122B Gene

    247 amino acids
    Molecular mass:
    26928 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH32419.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM122B Gene


neXtProt entry for FAM122B Gene

Proteomics data for FAM122B Gene at MOPED

Post-translational modifications for FAM122B Gene

  • Isoform 3 and isoform 4 are phosphorylated on Ser-62 and Ser-64
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for FAM122B Gene

Domains for FAM122B Gene

Protein Domains for FAM122B Gene


Suggested Antigen Peptide Sequences for FAM122B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM122 family.
  • Belongs to the FAM122 family.
genes like me logo Genes that share domains with FAM122B: view

No data available for Gene Families for FAM122B Gene

Function for FAM122B Gene

Phenotypes for FAM122B Gene

MGI mutant phenotypes for FAM122B:
inferred from 1 alleles
GenomeRNAi human phenotypes for FAM122B:
genes like me logo Genes that share phenotypes with FAM122B: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM122B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM122B Gene

Localization for FAM122B Gene

Subcellular locations from

Jensen Localization Image for FAM122B Gene COMPARTMENTS Subcellular localization image for FAM122B gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM122B Gene

Pathways for FAM122B Gene

SuperPathways for FAM122B Gene

No Data Available

Interacting Proteins for FAM122B Gene

Gene Ontology (GO) - Biological Process for FAM122B Gene


No data available for Pathways by source for FAM122B Gene

Transcripts for FAM122B Gene

Unigene Clusters for FAM122B Gene

Family with sequence similarity 122B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM122B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM122B Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b · 12c · 12d
SP1: - - - - -
SP2: - -
SP3: - - -
SP4: - - -
SP5: - - - - -
SP7: - - - - -
SP8: - -
SP9: - -

Relevant External Links for FAM122B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM122B Gene

mRNA expression in normal human tissues for FAM122B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for FAM122B Gene

This gene is overexpressed in Fetal testis (35.1), Testis (20.4), and Fetal ovary (13.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM122B Gene

SOURCE GeneReport for Unigene cluster for FAM122B Gene Hs.404706

genes like me logo Genes that share expressions with FAM122B: view

Expression partners for FAM122B Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM122B Gene

Orthologs for FAM122B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM122B Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia FAM122B 35
  • 91.35 (n)
  • 93.61 (a)
FAM122B 36
  • 88 (a)
(Mus musculus)
Mammalia Fam122b 35
  • 87.31 (n)
  • 85.83 (a)
Fam122b 16
Fam122b 36
  • 82 (a)
(Rattus norvegicus)
Mammalia Fam122b 35
  • 87.31 (n)
  • 85.83 (a)
(Bos Taurus)
Mammalia FAM122B 36
  • 76 (a)
(Monodelphis domestica)
Mammalia FAM122B 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia FAM122B 36
  • 83 (a)
(Pan troglodytes)
Mammalia FAM122B 36
  • 98 (a)
(Gallus gallus)
Aves FAM122B 35
  • 78.2 (n)
  • 80.45 (a)
FAM122B 36
  • 78 (a)
(Anolis carolinensis)
Reptilia FAM122B 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC550042 35
  • 67.8 (n)
  • 64.91 (a)
(Danio rerio)
Actinopterygii fam122b 36
  • 61 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4497 36
  • 13 (a)
Species with no ortholog for FAM122B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM122B Gene

Gene Tree for FAM122B (if available)
Gene Tree for FAM122B (if available)

Paralogs for FAM122B Gene

Paralogs for FAM122B Gene

(4) SIMAP similar genes for FAM122B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM122B: view

Variants for FAM122B Gene

Sequence variations from dbSNP and Humsavar for FAM122B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2355301 -- 134,792,689(-) aagtc(A/G)cttgc intron-variant
rs5933461 -- 134,769,399(+) ACTTC(A/G/T)TTTTG downstream-variant-500B
rs5975479 -- 134,770,430(+) ATGCT(A/G)TAACA utr-variant-3-prime
rs5978041 -- 134,780,263(+) GTGAG(A/T)GCCCT intron-variant
rs7472274 -- 134,786,268(+) tccca(A/G)cattt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM122B Gene

Variant ID Type Subtype PubMed ID
esv2740487 CNV Deletion 23290073
esv2740488 CNV Deletion 23290073
esv2740489 CNV Deletion 23290073
dgv1381e201 CNV Deletion 23290073
dgv1382e201 CNV Deletion 23290073

Relevant External Links for FAM122B Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM122B Gene

Disorders for FAM122B Gene

No disorders were found for FAM122B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM122B Gene

Publications for FAM122B Gene

  1. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4

Products for FAM122B Gene

Sources for FAM122B Gene

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